LOCUS       NM_153179              12928 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus polycystic kidney and hepatic disease 1 (Pkhd1), mRNA.
ACCESSION   NM_153179
VERSION     NM_153179.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 12928)
  AUTHORS   Fox,J.C., Hahnenstein,S.T., Hassan,F., Grund,A., Haffner,D. and
            Ziegler,W.H.
  TITLE     Defects of renal tubular homeostasis and cystogenesis in the Pkhd1
            knockout
  JOURNAL   iScience 27 (4), 109487 (2024)
   PUBMED   38550996
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12928)
  AUTHORS   Harafuji,N., Yang,C., Wu,M., Thiruvengadam,G., Gordish-Dressman,H.,
            Thompson,R.G., Bell,P.D., Rosenberg,A.Z., Dafinger,C., Liebau,M.C.,
            Bebok,Z., Caldovic,L. and Guay-Woodford,L.M.
  TITLE     Differential regulation of MYC expression by PKHD1/Pkhd1 in human
            and mouse kidneys: phenotypic implications for recessive polycystic
            kidney disease
  JOURNAL   Front Cell Dev Biol 11, 1270980 (2023)
   PUBMED   38125876
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 12928)
  AUTHORS   Walker,R.V., Yao,Q., Xu,H., Maranto,A., Swaney,K.F.,
            Ramachandran,S., Li,R., Cassina,L., Polster,B.M., Outeda,P.,
            Boletta,A., Watnick,T. and Qian,F.
  TITLE     Fibrocystin/Polyductin releases a C-terminal fragment that
            translocates into mitochondria and suppresses cystogenesis
  JOURNAL   Nat Commun 14 (1), 6513 (2023)
   PUBMED   37845212
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 12928)
  AUTHORS   Yang,C., Harafuji,N., Caldovic,L., Yu,W., Boddu,R.,
            Bhattacharya,S., Barseghyan,H., Gordish-Dressman,H., Foreman,O.,
            Bebok,Z., Eicher,E.M. and Guay-Woodford,L.M.
  TITLE     Pkhd1cyli/cyli mice have altered renal Pkhd1 mRNA processing and
            hormonally sensitive liver disease
  JOURNAL   J Mol Med (Berl) 101 (9), 1141-1151 (2023)
   PUBMED   37584738
REFERENCE   5  (bases 1 to 12928)
  AUTHORS   Ishimoto,Y., Menezes,L.F., Zhou,F., Yoshida,T., Komori,T., Qiu,J.,
            Young,M.F., Lu,H., Potapova,S., Outeda,P., Watnick,T. and
            Germino,G.G.
  TITLE     A novel ARPKD mouse model with near-complete deletion of the
            Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus
            presents with multiple phenotypes but not renal cysts
  JOURNAL   Kidney Int 104 (3), 611-616 (2023)
   PUBMED   37419448
  REMARK    GeneRIF: A novel ARPKD mouse model with near-complete deletion of
            the Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus
            presents with multiple phenotypes but not renal cysts.
REFERENCE   6  (bases 1 to 12928)
  AUTHORS   Hiesberger,T., Shao,X., Gourley,E., Reimann,A., Pontoglio,M. and
            Igarashi,P.
  TITLE     Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal
            domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis
  JOURNAL   J Biol Chem 280 (11), 10578-10586 (2005)
   PUBMED   15647252
  REMARK    GeneRIF: the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal
            domain has a role in Pkhd1 (ARPKD) gene transcription and renal
            cystogenesis
REFERENCE   7  (bases 1 to 12928)
  AUTHORS   Hiesberger,T., Bai,Y., Shao,X., McNally,B.T., Sinclair,A.M.,
            Tian,X., Somlo,S. and Igarashi,P.
  TITLE     Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene
            expression and produces renal cysts in mice
  JOURNAL   J Clin Invest 113 (6), 814-825 (2004)
   PUBMED   15067314
REFERENCE   8  (bases 1 to 12928)
  AUTHORS   Zhang,M.Z., Mai,W., Li,C., Cho,S.Y., Hao,C., Moeckel,G., Zhao,R.,
            Kim,I., Wang,J., Xiong,H., Wang,H., Sato,Y., Wu,Y., Nakanuma,Y.,
            Lilova,M., Pei,Y., Harris,R.C., Li,S., Coffey,R.J., Sun,L., Wu,D.,
            Chen,X.Z., Breyer,M.D., Zhao,Z.J., McKanna,J.A. and Wu,G.
  TITLE     PKHD1 protein encoded by the gene for autosomal recessive
            polycystic kidney disease associates with basal bodies and primary
            cilia in renal epithelial cells
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2311-2316 (2004)
   PUBMED   14983006
  REMARK    GeneRIF: In cultured renal cells, the PKHD1 gene product
            colocalized with polycystin-2, the gene product of autosomal
            dominant polycystic disease type 2.
REFERENCE   9  (bases 1 to 12928)
  AUTHORS   Nagasawa,Y., Matthiesen,S., Onuchic,L.F., Hou,X., Bergmann,C.,
            Esquivel,E., Senderek,J., Ren,Z., Zeltner,R., Furu,L., Avner,E.,
            Moser,M., Somlo,S., Guay-Woodford,L., Buttner,R., Zerres,K. and
            Germino,G.G.
  TITLE     Identification and characterization of Pkhd1, the mouse orthologue
            of the human ARPKD gene
  JOURNAL   J Am Soc Nephrol 13 (9), 2246-2258 (2002)
   PUBMED   12191969
  REMARK    GeneRIF: key features of human PKHD1 are highly conserved in the
            mouse suggesting that the complicated pattern of splicing is likely
            to be functionally important.
REFERENCE   10 (bases 1 to 12928)
  AUTHORS   Xiong,H., Chen,Y., Yi,Y., Tsuchiya,K., Moeckel,G., Cheung,J.,
            Liang,D., Tham,K., Xu,X., Chen,X.Z., Pei,Y., Zhao,Z.J. and Wu,G.
  TITLE     A novel gene encoding a TIG multiple domain protein is a positional
            candidate for autosomal recessive polycystic kidney disease
  JOURNAL   Genomics 80 (1), 96-104 (2002)
   PUBMED   12079288
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB661186.1, AY438374.1, AC161178.16, AY130764.1, AC166770.7 and
            AC166488.5.
            
            On Feb 24, 2007 this sequence version replaced NM_153179.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY130764.1, AY438374.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-547               BB661186.1         10-556
            548-1456            AY438374.1         422-1330
            1457-1735           AC161178.16        112155-112433
            1736-1825           AC161178.16        114142-114231
            1826-1916           AC161178.16        114319-114409
            1917-2059           AC161178.16        115530-115672
            2060-2187           AC161178.16        118484-118611
            2188-2363           AC161178.16        119269-119444
            2364-2502           AC161178.16        122816-122954
            2503-2630           AC161178.16        124436-124563
            2631-2815           AC161178.16        127001-127185
            2816-2938           AC161178.16        128224-128346
            2939-3044           AC161178.16        129836-129941
            3045-3320           AC161178.16        130488-130763
            3321-3451           AC161178.16        137588-137718
            3452-3587           AC161178.16        140624-140759
            3588-3783           AC161178.16        143301-143496
            3784-3851           AC161178.16        144122-144189
            3852-5453           AC161178.16        153767-155368
            5454-5597           AC161178.16        157735-157878
            5598-5817           AC161178.16        168920-169139
            5818-9161           AY130764.1         5810-9153
            9162-10037          AC166770.7         110499-111374       c
            10038-10364         AY438374.1         9915-10241
            10365-11996         AY130764.1         10357-11988
            11997-12928         AC166488.5         109881-110812
FEATURES             Location/Qualifiers
     source          1..12928
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 6.27 cM"
     gene            1..12928
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /note="polycystic kidney and hepatic disease 1"
                     /db_xref="GeneID:241035"
                     /db_xref="MGI:MGI:2155808"
     exon            1..147
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            148..284
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     CDS             230..12409
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /note="polyductin; TIG multiple domains 1; tigmin;
                     polycystic kidney and hepatic disease 1 protein;
                     fibrocystin"
                     /codon_start=1
                     /product="fibrocystin precursor"
                     /protein_id="NP_694819.2"
                     /db_xref="CCDS:CCDS14841.1"
                     /db_xref="GeneID:241035"
                     /db_xref="MGI:MGI:2155808"
                     /translation="MMLAWLVSLLSMEVLLLAKPYSSFQFEPAEGSLAGGTWITVVFD
                     GLDRSILYPNNGSQLQIDLVSVAIPTLRIPCDVSPAFVDLPVVTCQTRSLPSEADAGP
                     YSLEMRSGEQVLGTPCPGSLDSCTFKFSKDQTPVLYQVYPASGVPGEVVSVYGRVITT
                     WLETFDPDVDYIESPLILEAREDKWLTPCSLINRQTGSCFPIQEEHGLGNVQCRVEGD
                     YIGSQNVSFSVFNKGRSMVHKEAWLISAKQELFLYQTYPEILSVFPKVGSLGGRTDII
                     ITGDFFDPSARVTIAGIPCDIRYVSPRKIECTTRAPGNEARLTAPQAGNRGLRFEVGD
                     ATKDVELTEATPGYRWQIVPNASSPSGFWSKEGRPFRARLSGFFVAPQTNNYTFWIQA
                     DSQASLCFSSSEEPRTKVEVASVGVGTADWFDSWEQIGNEGSWHQKTTKLELQGGAKY
                     YLEAEQHGIAPSRGMRIGVQIHNTWLNPDVVNTYLLEKHQIRARAQRLPEIQVLHVSG
                     KGNFFLTWGNVSSQPVPANATAQQIQTTIEELLVVKCNLAPFSAHVLLRLGFEQGLEG
                     SRSDGVRTSSTEPFCGRFSLGQLGHLILIPEAADKGYQLDRYPYLCLAYRGHMNKTLD
                     MTVSFLFGFQTIMKNITCDWSLTDPHPESWQFTCINLWDTCLCHSEDIQSSLANTPLL
                     AHRIDIRPVVPEAGLLYVDEIILADTNVTVSQADSGRACPGGNVVESVSVVGVPPVYS
                     ISSWLAGCGSELPLITACSVSTEGTGDGSELIEVTAQRLQRTSPPLGGHFFLYLSDTV
                     IPDVPVRMSARQLHKLLQDSADESTSGYLNAGDFTVTEDLNSCYEHVWTLSWTTQTGD
                     LPNFIRVSDQNLTGVNPTVTARVVYDGGVFLGPIFGDMLATANQQTQVAVQVNDIPAY
                     CSGSCSFQYQQESTPSVDHVWYSLGSDVNLLVHFTGTGFPRDTQFLQVTVNKTSCEVL
                     FSNETNVACELALLPVGVHQIFMLVIPSGLAVHASGEDLLLHVEPRLDAVEPSTAAEI
                     GGRWVTLRGSSLEGVSLVLFGTQSCVIDAIRSNSQQIQCKVPPRGKDGYTVNVTVISG
                     DHSTVLARAFTYVSSLNPVIVSLSRNRSSIAGGEILFLGMSLLVNYTDLDVQIHVQDT
                     SAQVLSQTAWGLEVVLPPLVPGIHVISAFINGVSIRSQGVDLYIQYLTEVFSVEPCSG
                     SLLGGTLLSLLGTGLGRDPALIRVLVDNHPCDIVNLTEVNIWCETPPAVLPPRADVLT
                     VLASVEIWAGNTSFFHGPSLVGKGFTFTYEAAATPVVTAMWGEFRNNSVRFYVEGSNI
                     SDSVILLGSLKCELEVQFFGDSMNLSGCFFPLHSLEAGVYTLQVRHKRMGFANMSVVP
                     QKFELSPQIIAIFPTHGSKCGGTVLTVKGMAFSSRKRSVHVDISGPFACMILSLEDHT
                     VLCQTRFVGDQFSEASLALNITVLVNGLTSKCKGNCTLFIEEAATPIVDALTISISGS
                     LTMVLMRGRRLATTADEPIAFVDDQLPCHTTFFNTSHVACQIRDLAPGFHYLSAVHTS
                     AGYACLNSVSRNFFIVPQVLDYFPKDFSIHGGSLLTIKGTALRGWKATVVYVGRQACL
                     TVNFSSDFIQCIVPAGNGSAALEIDVNGVLYHIGLVDYSSIFTPELLSVSRSQDILTF
                     TVARISGAANVDIFIGTSPCLGVAGNRTVLQCMVPLLPAGEYLVTGYDHSRGWASSTL
                     ILVLRATVTSVTKNYGCLGGRLLHVLGAGFSPGNISAAVCGAPCQVLANATVSAFSCL
                     VLPLHVSLAFLCDLRHAEDSCKVRSSTYLRCDLTVSMGTERLPGSWPYVYLCEESSLC
                     LFEPDHWTESVFPSFSGLFLSPKVERDEVLIYNSSCNITMETEAEMECEMPNQPITAK
                     ITEIQKSWGQNTQGNFSFQFCRRWSRPHSWFPQRVPHDGDSVTVETGHLLLLDANTSF
                     LNSLHIKGGKLIFMDPGPIELRAHSILITDGGELHIGSEEKPFQGKARIKIYGSVHST
                     PFFPYGVKFLAVRNGTLSLHGSVPEVTVTYLQAAAHAGDKVLTLGEAVDWKPGDEAVI
                     TSGMTVAGAEATEVVVVETVHNADLHLRNPLRYSYDFRENWVAGENPILKPTVALLSR
                     NIIIQGNFTLERVKLLNSCQEANTAKGNLKHCLYSKSEKMLGARDLGARVIIQSFPEE
                     PSFVKLKGVQFRDLGQAFHKHLSSLALVGAMRGSYIQSCSVWNSFSRGLSMHRTWGLK
                     VDSNVFYKIVGHALLLGSYLDGRFSTSETVTGRKNGWWEQGSTIRNNVIISVSAAEGL
                     SGSEMLAPAGIYTFSPTNVMEGNRVCAAGYGYVFHLVTSQTLQAPLLSFNWNTAHSCT
                     RYGLLVYPKFQPPWNNDTGFTLFQNFMVWGSAGGAQIFRSNNLHLKNFQVYACRDFGI
                     DILESDANTLITDSFLLGHFTHKGSLCMSAGIKTPQRWELTISNTTFVNFDGNCVAIR
                     TCSGCFQGQGGYTVKTRQLKFVNSSNLVAFPFPHAAVLEDLDGSLSGKNGSHVLASME
                     TLSDTCLTNASFSQIVPGSVCGEAVLFHRMSIALANSLDVPKNLTITDISNKTITVNY
                     VEDTLSNYYGWMALLLDQETYSLQFESPWMNRSLQYSATFDSFAPGNYLLIMHRDLPP
                     YPDILLRCGSQVGHSLPFHPLPSQDRACDWFFNRQLRQLTYLVSGEGQVKVFLQLKPG
                     VPPSVSASTSVPESASRWSLPETWQDVEKGWGGYNHTIPGPGDDVLILPNKTVLVDTD
                     LPVLRCLYVMGTLEFPVDRSNVLSVACLLIAGGELKVGTLENPLEKDQRLLIFLRASE
                     EVVCDYFEGIHVDPGTIGVYGKLRLHSAYPKKSWVHLGADIAPGNERIIVHNAVDWQP
                     HDTIVLSSSSYEAHEAEVLTVKEVKGHHIRIYERLKHRHIGSTHTMEDGQQVHLAAEV
                     GLLTRNIRIQPDSSCRGRLLVGSFRKSSGEDFSGVLQLLNVEIQNMGLPLYSSIEFTG
                     VSAGSWVISSTVHQSCSVGIHASSSHGVILTDNVVFGTNGHGIDVEGQNYSLTNNLVI
                     LTMQSANSSPWVAGIKVNYAEDIILHGNVVAGSERLGFHVGGHGCSSEVLWSDNVVHS
                     SLHGLHLYKKHESNNCTGVSGFMAFKNFDYGAMVQTENSVDIQNITLVDNTVGLLAIT
                     YVSSALLSSVSTVQITLRNSVIVATSSSFDCIHDRKAPQSANWTSTDRAPSNPRGGRI
                     GILWPVSASEPNAWPQEPWHKVRSRHSVPGIMKLQDVTFSSFVKSCYSNDLDVCILPN
                     EYSTGVMYPITAERTRMLGIKDKNKFYFPVLQSSKDLVGTICPTLVCEYPRKYLFTDL
                     DGRTLGLPPPVSVFPRTEEEWTGSFLNTGIFREEQKCTFRAMNQGFFCKQTEHAVLIL
                     DNVDATWTIPKSHPLVSVTNGFVDTFSIVKDSDLCPPTSSLSTFYSILPTRQMTKVCF
                     PEQTPPFLRFLLLGNQRASKLILAVFYNEIQSPHVFLDKSFIPPTPLESAFSLLAEPS
                     GANYFDIMNNLLYVVLQGEEPVEIHSSVSIHLALTVTFSVLEKGWERAMLESLSDFFQ
                     IDPNQIRLTLEMPGNKETLEAIANSERKRKRNCPSVTCGGPSIRYGQRRPLMAEMTSL
                     KITPATTLETFSKVIVIEVGDLPNIRNSEPIQSLPSNRLQRLVNQVITAQQTGALENV
                     LGMTVGALLVTQSKGVTGYRNASSLITGNLIYTRPSELSILVQPSDGEVGIELPVQPR
                     LVFLDEKNERVESLGLPSEPWIISVSLEGASESVLKGCTLAETRDGYVTFSRLAVLIS
                     GSNWHLFFTVISPPGTNFTARSRTFVVLPVASKERSTIILALSLCSVASWVALSCLVC
                     CWFKKSKTRKIKPEDISESQAKEQKKNTHNSSKPRGLQAKTAKENTLMGEDMRMKVMQ
                     GMQSQFPQHSMDGVSKRKVSRLAVTEERTTTPAPKIPRITCVPGSLAQQLTLQEPGNW
                     QEAQQQLLRYQLAGRNQLLLLRPDLRQERKQGQEPSQLDKGSDCTGLSQEKATCIPTE
                     TFSLHTAPPETIQ"
     exon            285..362
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            363..504
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            505..613
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            614..671
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            672..750
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            751..825
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            826..890
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            891..930
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1001
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1103
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1104..1199
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1341
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1342..1456
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1457..1735
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1736..1825
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1826..1916
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1917..2059
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2060..2187
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2188..2363
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2364..2502
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2503..2630
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2631..2815
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2816..2938
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2939..3044
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            3045..3320
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            3321..3451
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            3452..3587
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            3588..3783
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            3784..3851
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            3852..5453
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            5454..5597
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            5598..5817
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            5818..5968
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            5969..6125
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            6126..6338
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            6339..6546
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            6547..6704
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            6705..6896
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            6897..7022
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            7023..7079
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            7080..7210
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            7211..7323
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            7324..7429
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            7430..7564
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            7565..7697
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            7698..7944
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            7945..8122
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            8123..8318
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            8319..8384
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            8385..8513
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            8514..8651
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            8652..8765
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            8766..8853
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            8854..9008
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            9009..9161
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            9162..10037
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            10038..10206
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            10207..10364
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            10365..11382
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            11383..11518
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            11519..11606
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            11607..11714
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            11715..11873
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            11874..11996
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     exon            11997..12928
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      12905..12910
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /note="hexamer: AATAAA"
     polyA_site      12928
                     /gene="Pkhd1"
                     /gene_synonym="FPC; Tigm1"
                     /note="major polyA site"
ORIGIN      
        1 gtgagttcca gtccaacagg aagtgagcta cctgcatctt agctagctag ctagctagct
       61 gcaggctggc ctgtcaccga ataacgcggc ttcgtttaga aggggacggt ttctctcatt
      121 tgaggcacaa ggctgacaca gcatcaggca caaaaactac atggcacaaa tcaaccctaa
      181 aaatgcttct aatatctgag gaatctcaag agagctgagc taactggaca tgatgcttgc
      241 ctggctggtc tctctgctga gtatggaagt actactgtta gcaaagcctt actcgagttt
      301 ccagtttgaa cccgcagaag gtagccttgc aggaggaaca tggatcacag ttgtatttga
      361 cggtttggat agaagtattc tttaccccaa caatggctct cagctgcaga tagacctggt
      421 gagtgtggca atacctacct tgaggatccc ctgtgacgtc tctccggcct tcgtggattt
      481 gcctgtggtg acatgccaga cgaggtctct tccatcagaa gcagatgcag ggccatactc
      541 cctggaaatg cgctctgggg agcaagtgct aggcactcca tgtcctggat cactagatag
      601 ctgtactttc aagttttcca aggatcagac acctgtttta tatcaagttt acccagcaag
      661 tggagttcca ggagaagtag tgtccgtgta cggccgggtc atcactacct ggctggagac
      721 cttcgatcct gatgtggact acatagagag cccattgatc ctagaagcta gagaagacaa
      781 atggcttact ccctgttccc ttataaacag gcagacagga agctgttttc ccatccagga
      841 ggagcatggc cttgggaatg tgcagtgtcg tgtggaaggc gattatattg gttctcagaa
      901 tgttagtttt tcagtattta acaaggggag gtcgatggtg cataaggaag cctggctcat
      961 cagtgctaaa caggaactgt tcctgtacca gacataccca gaaatcttat ccgtgtttcc
     1021 aaaagttggg agccttgggg gaagaacgga catcatcatt acgggagatt tctttgaccc
     1081 ttctgcccgg gttaccattg caggcatccc atgtgatatt agatatgtgt ctcccaggaa
     1141 gattgagtgc actaccaggg ctccaggaaa tgaagcaagg ctcactgctc ctcaggcagg
     1201 caatcgagga ctccgttttg aagttggaga tgctactaag gatgtggagc tgactgaagc
     1261 caccccaggg tacaggtggc agatagttcc taatgccagt tctccatctg gcttttggtc
     1321 aaaggaaggg agacctttca gagcacggct cagtgggttc ttcgtggcgc cacagacaaa
     1381 caattacaca ttctggatcc aggcagacag ccaagcttcc ttgtgtttca gttcttcaga
     1441 ggagccaagg accaaggtag aagtggcctc tgttggggtt ggcactgctg actggtttga
     1501 ctcttgggag cagatcggga atgaagggag ctggcaccag aagacaacca agctagaact
     1561 gcagggcgga gccaagtact acttggaagc agagcaacat gggatagctc ccagcagagg
     1621 gatgagaatt ggtgtccaga tccacaacac ctggttgaat ccagatgtgg tcaacactta
     1681 ccttctggag aaacaccaga tccgagctcg agcccagaga cttccagaaa tacaggtgtt
     1741 gcatgtgtca ggtaaaggaa actttttcct tacttggggc aatgtctcca gccaaccagt
     1801 tcctgcaaat gccacagccc aacagatcca aaccaccatt gaagagttgc ttgtggtgaa
     1861 atgcaatctg gcaccgtttt cggcccatgt tcttctccgg cttggatttg agcaaggttt
     1921 agaaggctcc aggtctgatg gggtccgcac cagttcaact gaacccttct gtggcagatt
     1981 cagccttggt caacttggac atcttatcct aattccagag gctgccgaca agggctatca
     2041 gctggatcga tacccgtatc tgtgccttgc gtacagaggc catatgaaca agaccctgga
     2101 catgactgtt tctttcctct ttggcttcca aactatcatg aagaatatca cctgtgattg
     2161 gagtcttacc gatccccacc ctgagagctg gcagttcact tgcattaacc tctgggacac
     2221 atgtctatgt cactctgagg atatccagtc ttctctggca aacaccccat tgctggctca
     2281 tcggattgac atccgccccg tggttccgga ggcaggcctg ctctatgtgg atgaaattat
     2341 tcttgcagat accaacgtaa cagtttctca agctgattct ggaagagcct gcccaggtgg
     2401 gaatgtggtg gagtcagtat cggtggtggg agtccctccg gtctacagca taagctcctg
     2461 gttggcagga tgtggctcag agctccctct catcactgca tgctctgtgt ccacggaggg
     2521 aacaggagat ggatctgaat tgattgaggt gacagctcaa agactccaga ggacaagccc
     2581 acctttggga ggacacttct tcctttacct ctctgacaca gtgatacctg atgttccggt
     2641 gcgcatgtct gcccgacagc tgcataagct actgcaggac agtgctgatg agtccacatc
     2701 tggatatctc aatgccggtg acttcactgt gacagaggat ctgaattcct gctatgaaca
     2761 tgtgtggact ctttcttgga ccactcagac tggggatttg cccaatttta tcagggtctc
     2821 tgatcaaaat cttactgggg tgaatcccac tgtaactgct cgcgtggtat atgatggtgg
     2881 agttttcctt ggacccatct ttggagacat gttggctact gccaaccagc aaactcaggt
     2941 ggctgtacag gtgaatgaca taccagccta ttgttcaggc tcctgttctt tccaatacca
     3001 gcaagagtca actcccagtg tggatcatgt gtggtactcc cttggaagcg atgtcaactt
     3061 gctggttcat tttactggaa ctggtttccc tagagacacc cagttcttac aggtcacggt
     3121 gaacaaaact agctgtgaag ttcttttctc aaatgaaacc aatgtggcct gtgagctggc
     3181 tctgctacca gttggagtgc accagatttt tatgctggtg ataccgtcag gccttgctgt
     3241 tcatgccagt ggagaagacc tcctcctgca tgtggaaccc aggctggatg ctgtggagcc
     3301 ttctacagct gcagagattg gaggacggtg ggttactctc cgaggctcta gtttggaagg
     3361 tgttagcctg gtgttatttg gaactcagtc atgtgtcatt gatgccatta gaagcaattc
     3421 acaacaaatt caatgcaaag tcccacctag ggggaaagat ggatacactg tgaatgtgac
     3481 tgtgatcagt ggcgaccact ctacagttct tgccagagca tttacatatg tctcctcttt
     3541 aaatccagtg attgtgtcat tgagcagaaa cagaagcagc atagcaggag gtgagattct
     3601 gttccttggg atgtcactgc tggtgaacta cacagatctg gatgtgcaaa tccatgtgca
     3661 ggatacttct gctcaggtcc tttcacagac agcgtgggga ctggaggtag tgttgcctcc
     3721 actagtacct ggcatccatg tgatttcagc attcatcaat ggagtcagta ttcgttcaca
     3781 aggggttgat ctctatatcc agtacctcac tgaagttttc agcgtggaac cttgctctgg
     3841 gtctctcttg ggtggaactc tcctcagtct cttaggaaca ggactgggca gagacccagc
     3901 tctgattcgg gtgcttgtgg acaatcatcc ttgtgatatt gtgaacttaa cggaagtgaa
     3961 catttggtgt gagactcctc cagctgtact accacccagg gcagatgttc tcactgtcct
     4021 agcctctgtg gagatctggg ctggcaacac ttccttcttc catggaccaa gcttggtggg
     4081 gaagggcttt accttcacat atgaagcagc agcaacacca gtggtcactg ctatgtgggg
     4141 agaattcagg aacaacagtg tgaggtttta tgtggaagga agtaacatct ctgactcagt
     4201 cattcttttg gggtccttga aatgtgaact tgaagtacaa ttttttggtg atagcatgaa
     4261 cttgtctggg tgcttttttc ctctccatag tttggaagcc ggggtctata ctctccaagt
     4321 tcgtcacaag aggatggggt ttgccaatat gtctgtggtg cctcagaaat ttgagttgtc
     4381 acctcagatt attgccatct tcccaacaca tgggtctaaa tgtggtggga cagtacttac
     4441 tgtgaagggc atggccttca gttccagaaa gaggtcagtt catgttgaca tttcaggccc
     4501 ttttgcttgc atgattttga gtttggaaga ccacacagtc ctatgccaga ccagatttgt
     4561 gggtgaccaa ttttctgaag catcactggc tctaaacatc acagttctgg tcaatgggct
     4621 gaccagcaag tgtaagggga actgtacact cttcatagag gaagcagcaa ctcctattgt
     4681 ggatgctttg actataagca tcagtgggtc tctaaccatg gtgctgatga gaggccggag
     4741 gttagctacc actgctgatg agccaatagc atttgtggat gatcaacttc cctgccacac
     4801 aacattcttc aataccagcc atgtggcatg ccagataaga gatttggccc caggcttcca
     4861 ctatctgtca gctgttcata caagtgctgg atatgcttgc ctcaatagtg tttctagaaa
     4921 cttcttcatc gtgcctcagg tgcttgatta ttttcctaag gactttagca tccatggtgg
     4981 aagtctcttg acgataaaag gcacagccct gcgaggatgg aaagctacag ttgtctatgt
     5041 tggccggcag gcttgtctaa cagtgaactt cagctctgac ttcatccagt gcattgttcc
     5101 tgcaggaaat ggctctgctg ctctggaaat tgatgtgaat ggagttttat accacatagg
     5161 acttgttgat tacagcagta tcttcacccc agaattgctt tctgtttcac ggagccaaga
     5221 catcttaacc tttacagtgg cccggatctc aggggctgca aatgttgaca tttttattgg
     5281 gacatcaccg tgtctaggtg ttgctggcaa ccgtacagtt ctccagtgca tggtccctct
     5341 gcttcctgct ggggagtatc ttgtcacagg ttatgatcac agccgagggt gggcctcatc
     5401 cactctcatt cttgtgctga gagccactgt gacctcagtg accaagaact atggttgcct
     5461 gggtggaagg cttttgcatg tgctcggagc aggattttct ccagggaaca tctcagctgc
     5521 cgtatgtggt gctccatgcc aagtcttggc taatgcgaca gtgtctgcct tcagctgctt
     5581 ggttctgccc ctgcatgtgt ccttggcttt cctatgtgac ctgaggcatg cagaagacag
     5641 ctgtaaagtc aggagctcca cctacttgcg atgtgatttg actgtctcca tggggacaga
     5701 gagactgcct ggatcctggc cttatgtcta cctttgtgaa gagagttccc tgtgcctctt
     5761 cgaaccagat cactggacag agtcagtctt tccatcgttc tcaggcctct tcctcagccc
     5821 taaagtggaa agagatgaag ttctcatcta taatagctcc tgtaacatta ccatggaaac
     5881 tgaggcagag atggagtgtg agatgcctaa tcagccaatt accgccaaga ttactgaaat
     5941 acagaaaagc tggggccaga acactcaggg caacttttcc ttccaattct gccgaaggtg
     6001 gtccaggcct cacagttggt ttcctcaaag agtgccacac gatggcgaca gtgtcacagt
     6061 ggagaccggt cacctgctac tgcttgatgc gaacactagc ttcctgaact ccctgcacat
     6121 taaaggtggc aagctgatct tcatggatcc aggacccatt gagctcagag cccactccat
     6181 ccttattaca gatggtggag agctccatat tggatctgag gaaaagcctt tccaaggcaa
     6241 agctcggatc aaaatctatg gaagtgtcca ttccactccc ttctttccct atggagtcaa
     6301 gttcctagct gtgaggaatg gaactctttc cctgcatggt tcagttccag aggttactgt
     6361 cacctatctt caagcagctg cacatgcagg agacaaagtg ttgactctgg gggaagctgt
     6421 ggactggaag cctggggatg aggctgtcat taccagtggg atgactgtag caggagctga
     6481 agcaacagaa gttgttgttg tagaaactgt ccacaatgca gacctccatc tcaggaaccc
     6541 cctgagatat tcctatgatt tcagagagaa ctgggtagct ggagagaatc ctattttgaa
     6601 gccaacagtt gctctcctca gcaggaacat tatcatccaa ggaaacttca cacttgagag
     6661 ggtaaagctt ctcaattcat gccaggaggc caacactgct aaaggtaact tgaagcactg
     6721 tttgtattct aagagtgaga agatgctggg agccagggat ctgggggcca gagtcatcat
     6781 tcagtccttc ccagaggaac ccagcttcgt caagctgaag ggagtgcagt tcagagacct
     6841 gggacaggcc ttccataagc acctgagctc actcgcactg gtgggagcta tgagaggctc
     6901 ttatatccaa agctgttcag tgtggaactc cttcagcaga ggccttagca tgcacaggac
     6961 ctggggtctg aaggtggaca gcaatgtatt ctataagatt gtagggcatg ccctgctgct
     7021 ggggtcctac ctggacggaa ggtttagcac tagtgagact gttactggaa gaaaaaatgg
     7081 ttggtgggaa cagggaagta caataagaaa caatgtgatc atcagtgttt ctgcagctga
     7141 gggactgtcc ggttctgaaa tgttggcacc agctggcatc tacactttca gtcccaccaa
     7201 tgtgatggag ggcaacagag tgtgtgcagc tggctatgga tatgtcttcc accttgtgac
     7261 cagccaaaca ttacaagctc cactcctctc attcaattgg aatactgctc attcttgtac
     7321 aagatatggt ctccttgtat atcctaaatt tcaaccacct tggaataatg acactggctt
     7381 cactctgttc caaaacttca tggtttgggg aagtgctggt ggtgcccaga tttttagaag
     7441 taacaatcta cacctgaaaa acttccaagt ttatgcatgc agagattttg gaattgacat
     7501 tttggaaagt gatgcgaaca ctttgattac cgacagcttt ttacttggtc atttcaccca
     7561 caagggaagt ctatgtatgt cagctgggat caaaactccc caaagatggg aactgaccat
     7621 ttcgaacaca acttttgtta attttgatgg caactgtgtg gccatcagaa cctgttctgg
     7681 ctgtttccaa ggacagggtg gctatactgt gaagaccagg caattgaagt ttgtaaactc
     7741 ttcaaattta gtagcatttc catttcctca tgcagcagtt ctggaagact tagacgggtc
     7801 cctgtctggg aaaaatgggt ctcatgttct tgcatctatg gaaaccctct cagacacatg
     7861 cttgaccaat gcaagcttca gtcagattgt ccctggcagc gtctgtggcg aagctgttct
     7921 cttccatcgt atgtctattg ctctagccaa tagccttgat gttcctaaga atttaaccat
     7981 tactgacatc agtaataaga caatcactgt caattatgtg gaagacaccc tgtctaacta
     8041 ctacggctgg atggctctgc tcttggatca agagacctac tcgctgcagt ttgagagccc
     8101 ttggatgaac agatctctgc agtactcagc aacgtttgac agctttgctc ctggaaatta
     8161 cctcctgata atgcacaggg acctaccacc ttatcctgac atcctcctca gatgtgggag
     8221 tcaggtgggc cattcacttc catttcatcc tttgcctagt caagacagag cctgtgattg
     8281 gttcttcaat aggcaattga ggcagctcac ctacctggtt tcaggtgaag gtcaagttaa
     8341 ggtatttctc caactgaagc ctggtgtacc tccaagtgtt tcagcttcta catcagtacc
     8401 tgaatcagct tcaagatggt ctcttcctga aacatggcaa gatgttgaaa aaggctgggg
     8461 aggatacaac cacaccatcc caggacccgg tgatgatgtc ttgattttac ccaacaagac
     8521 tgttcttgtg gatactgatc tcccagtgct tcgatgcctc tatgtgatgg gtaccttaga
     8581 attccctgtg gacagaagca acgttctgag tgtggcatgc ttactcattg caggagggga
     8641 gctgaaagta ggcactttgg aaaacccctt agaaaaggac caaagacttc tgatattcct
     8701 tagagcctca gaagaagtcg tctgtgacta ttttgaagga attcatgttg acccaggaac
     8761 aattggagtt tatgggaaac ttcgccttca cagtgcttat cctaagaaat cctgggtaca
     8821 ccttggagct gacattgcac cgggaaatga gaggattatt gtacacaatg cagtggattg
     8881 gcagcctcat gacacaattg tcctcagctc ttcttcttat gaggctcatg aggcagaggt
     8941 cctcactgtg aaggaagtca agggccatca catcaggatc tatgaacgtc taaagcacag
     9001 gcacattgga agtacccaca ccatggagga tggtcaacag gttcatttgg ctgctgaggt
     9061 tgggctgttg accagaaaca ttagaattca gcctgactca tcctgtagag ggagactcct
     9121 tgtggggtcc ttcaggaagt ctagcggaga agacttttct ggtgttcttc aacttctcaa
     9181 tgtagaaatt cagaacatgg ggttgccatt gtattcatct attgaattca ctggtgtatc
     9241 agctggatcc tgggtaatat cttctactgt gcatcaaagt tgcagtgtgg gcatccatgc
     9301 atcttccagc catggcgtga ttttaactga taatgtagtg tttggcacaa atggccatgg
     9361 catcgatgtg gagggtcaga actattctct caccaataac cttgtcattc tgacaatgca
     9421 gtcagcaaac tcatctcctt gggtggcagg aatcaaagtg aactatgcag aggacatcat
     9481 tctccatggc aatgtggtgg caggatctga gagacttggc tttcatgtcg gtggtcatgg
     9541 gtgctcctct gaagtgcttt ggtctgataa tgtggtccac tcaagcctcc atggccttca
     9601 cctctacaag aaacatgaat ccaataactg tactggtgtc tctggattta tggcttttaa
     9661 gaactttgac tatggtgcca tggttcagac agagaatagt gtggacatac agaatatcac
     9721 tctggtagac aatactgttg gtcttttggc tatcacatat gtatcttctg ctctcctgag
     9781 ctctgtcagt actgtacaga ttacacttag gaattcagtc attgtggcca ctagctcctc
     9841 ttttgactgc atccacgaca gaaaggctcc tcagtcagcc aactggacat caacagatag
     9901 agcaccttcc aatcccagag gaggccgaat cggtattctg tggcctgttt ctgcctcaga
     9961 accaaatgca tggccccagg agccatggca caaagtaagg agccgtcatt cagtcccagg
    10021 aattatgaag cttcaagatg tcaccttttc tagttttgtg aagagttgct atagcaacga
    10081 cctggatgtc tgcatcctgc ctaatgagta tagcactgga gtcatgtacc caataacagc
    10141 agagaggacc agaatgctgg ggataaagga caaaaacaag ttctactttc ctgtattaca
    10201 gtccagcaaa gacttagtgg gaaccatttg tcccacattg gtctgtgaat atccaagaaa
    10261 atacctcttc acagatcttg atgggagaac actgggtcta cccccaccag tttctgtgtt
    10321 tccaaggaca gaggaagagt ggactggatc gttcctcaat acaggtatat tcagagaaga
    10381 acagaaatgc acattccgag cgatgaacca gggcttcttc tgtaagcaga ctgagcatgc
    10441 ggtcctaatt ctcgataatg ttgatgcaac ttggacaatc cccaaatcac acccacttgt
    10501 atctgttact aatggctttg tggacacatt tagcattgtg aaggacagtg atttatgccc
    10561 tcccacaagc tctctgtcta ctttttattc catcttgccc accagacaaa tgaccaaggt
    10621 atgctttcca gagcaaactc ctccattcct gcgttttctt ctattgggaa accaaagagc
    10681 ctccaagctc atcttggctg tattctacaa tgagattcag agccctcatg ttttcttaga
    10741 caagagcttt attccaccta ctccattaga gtcagcattt tcattgttgg ctgagccctc
    10801 tggtgccaac tattttgaca tcatgaataa cctcttgtat gttgtcctgc aaggagagga
    10861 gcctgttgaa atacattcaa gtgtttccat tcatttggct ttgactgtga cattttcagt
    10921 cctagaaaag ggctgggaga gagcaatgct tgaaagccta agtgacttct ttcagattga
    10981 cccaaaccaa atcagactca ctcttgagat gcctggcaac aaagagacct tagaggccat
    11041 tgcaaacagt gaaagaaaac gaaagcgcaa ttgcccatct gtaacttgtg gtggcccttc
    11101 tatcagatat ggtcaacgta gacctctcat ggcagaaatg acatcactta agatcacacc
    11161 agcaacaact ctggaaactt tctcaaaggt gattgtcatt gaagttggtg acctgccaaa
    11221 cataaggaac agtgaaccca ttcagtcctt accaagtaac agattacaga gattggtgaa
    11281 ccaggttatc actgctcaac agactggagc tctagaaaat gtcctaggta tgactgttgg
    11341 ggccctacta gtgactcagt ccaagggagt cacaggatat agaaatgcaa gtagtttaat
    11401 aactgggaac ctgatataca cccggccctc agagctttcc atcctggtgc agccttctga
    11461 tggagaagtg ggaatagaat tgccagttca gccacggctt gtcttcctgg atgagaagaa
    11521 tgagagagta gagtctttgg gtctcccctc agaaccctgg attatttcag tttctctaga
    11581 gggagcatct gaatcagtgc ttaaagggtg taccctggca gaaacacggg atggctatgt
    11641 gaccttttct agattggctg tcttgatctc tgggtcaaac tggcacttgt tttttactgt
    11701 tatatcccct ccaggtacta attttacagc tcgatcaagg accttcgttg tcttgcctgt
    11761 ggctagcaag gagagatcaa ctatcatctt ggccttgtcc ctgtgctcag tggcatcatg
    11821 ggtggctctg agctgtctcg tttgctgctg gtttaagaaa agcaaaacca gaaaaataaa
    11881 accagaagac atatctgaat cccaggctaa ggaacaaaag aagaataccc ataattcctc
    11941 caaacccaga ggactacaag caaagacagc aaaagagaac actttgatgg gagaagatat
    12001 gagaatgaag gtcatgcagg gaatgcagag ccagtttccc caacactcaa tggatggagt
    12061 gtccaaaagg aaagttagcc gccttgctgt tacagaggaa agaacaacta cacctgcccc
    12121 aaagattccc agaatcacct gtgttccagg atctcttgct cagcagctga cactgcagga
    12181 gcctgggaac tggcaggagg cccaacagca gttgctcaga taccagctgg caggccgcaa
    12241 tcagctgctc ctgttacgcc cagacctcag gcaagagagg aaacagggtc aggagcctag
    12301 ccagctggac aaagggagtg actgcactgg actgtctcaa gagaaggcca cttgcattcc
    12361 cactgagact ttcagcctcc atactgctcc accagaaacc atccagtaac agctgtgggc
    12421 atggagcact gtatgaaaag gagaaaatgt tcaaaattat ttctgcattg taaatgggaa
    12481 aggagaggtc tgatctgttt ggacaaataa ggagaatgtg aactctaaat ctttaaactt
    12541 taatatggaa gacagtcagg caaatgcttg tatactgaga ttgtaatcaa tcatgtctct
    12601 tgtacctctc attgatccta accaattcca gcaaataata ggacctcaaa aacttgctga
    12661 tattttctgg ggttcaaact ggttacgttg cagccaactt aatacctgtg ctataaatac
    12721 tgaatttcag taagcaggaa ctgtgattaa gattccctat agtcaacact caggatgctt
    12781 taggcttgtc ttatggaaga cctgttatag ctttagttag ctgatgttgt atctgcagtg
    12841 ctatagaaat acccaggaga tattttacac caacgtttac cctccctcca aacagagtta
    12901 acttaataaa agttacttgt agatttta
//
