LOCUS       NM_001360106            3418 bp    mRNA    linear   ROD 31-JUL-2024
DEFINITION  Mus musculus pitrilysin metallepetidase 1 (Pitrm1), transcript
            variant 2, mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001360106 XM_006516508
VERSION     NM_001360106.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3418)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3418)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3418)
  AUTHORS   Du,F., Yu,Q., Yan,S., Zhang,Z., Vangavaragu,J.R., Chen,D., Yan,S.F.
            and Yan,S.S.
  TITLE     Gain of PITRM1 peptidase in cortical neurons affords protection of
            mitochondrial and synaptic function in an advanced age mouse model
            of Alzheimer's disease
  JOURNAL   Aging Cell 20 (5), e13368 (2021)
   PUBMED   33951271
REFERENCE   4  (bases 1 to 3418)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3418)
  AUTHORS   Perez-Garcia,V., Fineberg,E., Wilson,R., Murray,A., Mazzeo,C.I.,
            Tudor,C., Sienerth,A., White,J.K., Tuck,E., Ryder,E.J., Gleeson,D.,
            Siragher,E., Wardle-Jones,H., Staudt,N., Wali,N., Collins,J.,
            Geyer,S., Busch-Nentwich,E.M., Galli,A., Smith,J.C., Robertson,E.,
            Adams,D.J., Weninger,W.J., Mohun,T. and Hemberger,M.
  TITLE     Placentation defects are highly prevalent in embryonic lethal mouse
            mutants
  JOURNAL   Nature 555 (7697), 463-468 (2018)
   PUBMED   29539633
REFERENCE   6  (bases 1 to 3418)
  AUTHORS   Town,L., McGlinn,E., Fiorenza,S., Metzis,V., Butterfield,N.C.,
            Richman,J.M. and Wicking,C.
  TITLE     The metalloendopeptidase gene Pitrm1 is regulated by hedgehog
            signaling in the developing mouse limb and is expressed in muscle
            progenitors
  JOURNAL   Dev Dyn 238 (12), 3175-3184 (2009)
   PUBMED   19877269
  REMARK    GeneRIF: Pitrm1 is expressed in Pax3-expressing myoblast
            progenitors in the limb, the dermomyotome, and developing muscles
            of the face and torso.
REFERENCE   7  (bases 1 to 3418)
  AUTHORS   Chen,H.W., Chen,J.J., Yu,S.L., Li,H.N., Yang,P.C., Su,C.M.,
            Au,H.K., Chang,C.W., Chien,L.W., Chen,C.S. and Tzeng,C.R.
  TITLE     Transcriptome analysis in blastocyst hatching by cDNA microarray
  JOURNAL   Hum Reprod 20 (9), 2492-2501 (2005)
   PUBMED   15919778
REFERENCE   8  (bases 1 to 3418)
  AUTHORS   Ehrich,T.H., Hrbek,T., Kenney-Hunt,J.P., Pletscher,L.S., Wang,B.,
            Semenkovich,C.F. and Cheverud,J.M.
  TITLE     Fine-mapping gene-by-diet interactions on chromosome 13 in a LG/J x
            SM/J murine model of obesity
  JOURNAL   Diabetes 54 (6), 1863-1872 (2005)
   PUBMED   15919810
REFERENCE   9  (bases 1 to 3418)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   10 (bases 1 to 3418)
  AUTHORS   Suemizu,H., Aiba,K., Yoshikawa,T., Sharov,A.A., Shimozawa,N.,
            Tamaoki,N. and Ko,M.S.
  TITLE     Expression profiling of placentomegaly associated with nuclear
            transplantation of mouse ES cells
  JOURNAL   Dev Biol 253 (1), 36-53 (2003)
   PUBMED   12490196
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159228.2.
            
            On Jan 27, 2018 this sequence version replaced XM_006516508.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK164235.1, AK167426.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-73                AC159228.2         120694-120766       c
            74-173              AC159228.2         119241-119340       c
            174-280             AC159228.2         116183-116289       c
            281-432             AC159228.2         115590-115741       c
            433-547             AC159228.2         113455-113569       c
            548-644             AC159228.2         113275-113371       c
            645-805             AC159228.2         112221-112381       c
            806-932             AC159228.2         111035-111161       c
            933-1021            AC159228.2         110679-110767       c
            1022-1150           AC159228.2         109440-109568       c
            1151-1264           AC159228.2         108780-108893       c
            1265-1361           AC159228.2         108225-108321       c
            1362-1496           AC159228.2         106836-106970       c
            1497-1635           AC159228.2         105409-105547       c
            1636-1752           AC159228.2         103816-103932       c
            1753-1885           AC159228.2         101441-101573       c
            1886-2006           AC159228.2         100139-100259       c
            2007-2083           AC159228.2         99948-100024        c
            2084-2249           AC159228.2         99558-99723         c
            2250-2350           AC159228.2         98221-98321         c
            2351-2471           AC159228.2         95762-95882         c
            2472-2543           AC159228.2         94492-94563         c
            2544-2656           AC159228.2         93794-93906         c
            2657-2782           AC159228.2         91408-91533         c
            2783-2928           AC159228.2         90337-90482         c
            2929-3031           AC159228.2         89403-89505         c
            3032-3418           AC159228.2         88887-89273         c
FEATURES             Location/Qualifiers
     source          1..3418
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 3.25 cM"
     gene            1..3418
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /note="pitrilysin metallepetidase 1"
                     /db_xref="GeneID:69617"
                     /db_xref="MGI:MGI:1916867"
     exon            1..73
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..3125
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /note="isoform 2 is encoded by transcript variant 2;
                     pitrilysin metalloprotease 1; presequence protease,
                     mitochondrial; pitrilysin metalloproteinase 1; nuclear
                     transplantation upregulated protein 1"
                     /codon_start=1
                     /product="presequence protease, mitochondrial isoform 2"
                     /protein_id="NP_001347035.1"
                     /db_xref="GeneID:69617"
                     /db_xref="MGI:MGI:1916867"
                     /translation="MWRFSGRRGLCAVQRLSCGVHHRVWREKSDQACERALQYKVGEK
                     IHGFTVNQVTPVPELFLTAVKLSHDNTGARYLHLAREDKNNLFSVQFRTTPMDSTGVP
                     HVLEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAMTASDYTIYPFSTQNPKDFQNLLS
                     VYLDATFFPCLRELDFWQEGWRLEHENPRDPQTPLIFKGVVFNEMKGAFTDNERIFSQ
                     HLQNKLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFQLEGHL
                     KQIHEEALSKFQRLEQSTAVPAQPHWDKPREFHITCGPDSLATETAKQTTVSVSFLLP
                     DITDTFEAFTLSLLSSLLIAGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGL
                     QGIAEKDVKTVRELVDRTIEEVIEKGFEDDRIEALLHKIEIQTKHQSASFGLTLTSYI
                     ASCWNHDGDPVELLQIGSQLTRFRKCLKENPKFLQEKVEQYFKNNQHKLTLSMKPDDK
                     YYEKQTQMETEKLEQKVNSLSPADKQQIYEKGLELQTQQSKHQDASCLPALKVSDIEP
                     SMPFTKLDIGLAAGDIPVQYCPQPTNGMVYFRAFSSLNTLPEDLRPIVPLFCSVLTKL
                     GCGILNYREQAQQIELKTGGMSVTPHVLPDDSQLDTYEQGVLFSSLCLERNLPDMMHL
                     WSEIFNNPCFEEEEHFKVLVKMTAQELSNGISDSGHLYAALRASKTLTPSGDLQETFS
                     GMDQVKVMKRIAEMTDIKPILRKLPRIKKYLLNCDNMRCSVNATPQQMPQAEKEVENF
                     LRNVGRSKKERKPVRPHIVEKPTPSGPSGAAHVSGSQIVRKLVTDPTFKPCQMKTHFV
                     LPFPVNYIGECVRTVPYADPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLTHSG
                     IFTLYSYRDPNSIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDSPVAPSDKGM
                     DHFLYGLSDEMKQAYREQLFAVNHDKLTSVSHKYLGIGKSTHGLAILGPENSKIAKDP
                     SWIIK"
     exon            74..173
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            174..280
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            281..432
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            433..547
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            548..644
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            645..805
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            806..932
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1021
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1150
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1264
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1361
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            1362..1496
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            1497..1635
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            1636..1752
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..1885
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..2006
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            2007..2083
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            2084..2249
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            2250..2350
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            2351..2471
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            2472..2543
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            2544..2656
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            2657..2782
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            2783..2928
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            2929..3031
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
     exon            3032..3418
                     /gene="Pitrm1"
                     /gene_synonym="2310012C15Rik; mKIAA1104; MP-1; MP1; Ntup1;
                     PreP"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacgctggtc acatgccatg tggcgcttca gcggtcggcg gggactctgc gctgtacagc
       61 ggctgagctg cggggtacac cacagagtat ggagggagaa gagtgaccaa gcctgtgaac
      121 gagctctaca gtataaagtg ggagagaaaa tccacgggtt cactgtaaac caggtcactc
      181 ctgtccccga gctgttcctg acagccgtga agctcagcca tgacaacacg ggagccagat
      241 acctgcacct ggcaagggaa gacaagaaca acttattcag tgtgcagttc cgcacaaccc
      301 caatggatag cactggggtc ccacatgttc tcgagcatac ggtcctgtgc ggctctcaga
      361 agtacccgtg cagagatcct ttcttcaaaa tgctcaacag gtcactgtcc acatttatga
      421 atgccatgac agccagcgat tacacgatat atccgttttc cactcaaaat cccaaagatt
      481 ttcagaacct cctctccgtg tatttggatg caactttctt cccctgcttg agggaactgg
      541 acttctggca ggaaggatgg cgtctggagc atgagaatcc ccgagaccct cagacgccct
      601 tgatctttaa gggggtcgtc ttcaacgaga tgaaaggggc atttacagac aatgagagga
      661 tattctccca gcacctgcag aacaagctgc ttcctgacca cacctactcc gtggtttctg
      721 gaggggaccc actgtgcatc ccggagctca cgtgggaaca gctgaaacag ttccacgcta
      781 ctcattatca cccaagcaat gccaggttct tcacttatgg caattttcag ctggaaggac
      841 acctgaaaca aattcacgaa gaagccctga gtaaattcca gagattggag cagagtacag
      901 cagtgcctgc ccagccgcac tgggataagc ctagggaatt ccatataaca tgtggcccag
      961 attcactagc tacggagact gccaagcaga caactgtcag cgttagcttc ctcttaccgg
     1021 atatcactga cacatttgaa gccttcacct tgagccttct gtcctccctc ctgattgctg
     1081 gacccaactc ccccttctac aaagctttga tcgagtctgg actcggcaca gacttttctc
     1141 ctgatgttgg atataatggc tatacacggg aggcttactt cagtgtcggg ctccaaggga
     1201 tcgcagagaa agatgtcaag acggtcagag agctcgtaga caggacaatc gaagaagtta
     1261 tagagaaagg atttgaagat gatcggattg aagctctgct tcataaaatc gaaattcaaa
     1321 cgaagcatca gtcagccagc tttggcctga ccctgacgtc atatatagct tcttgctgga
     1381 accatgatgg ggaccctgtg gagctcctgc agattggaag tcagctgact agatttagga
     1441 agtgccttaa ggaaaatcca aaatttttac aagaaaaagt agaacaatat tttaagaaca
     1501 atcagcacaa gctgacttta tccatgaagc cagacgacaa gtattatgaa aagcaaactc
     1561 agatggagac agaaaagctg gagcaaaagg tgaattctct ctccccggcg gacaagcagc
     1621 agatctacga gaaaggttta gaactacaga cgcagcaaag taaacatcaa gacgcctcct
     1681 gcctcccagc attgaaagtc tcggacattg agccctccat gcctttcacc aagcttgaca
     1741 tcggccttgc agctggagac atccctgtgc agtactgccc acagcccacc aacggcatgg
     1801 tgtatttccg agccttttcc agtttaaaca cgctgccgga ggacctgagg cccattgtgc
     1861 ctctcttttg cagcgtgctg accaagctgg gttgtggcat ccttaactac agagagcaag
     1921 cccaacagat tgagctcaag acaggaggca tgagtgtcac gccccatgtg ctccctgacg
     1981 actcacagct ggatacctac gagcagggtg tgttattttc atctctctgc ctggagcgga
     2041 acctgccaga catgatgcat ctgtggagcg aaatatttaa caatccatgc tttgaagaag
     2101 aagaacactt caaagtgttg gtgaagatga ccgctcagga gctctccaat ggaatttcag
     2161 actcggggca tctctatgca gccctcagag caagcaagac actgacacct tcaggggact
     2221 tgcaggagac cttcagtggg atggatcagg tgaaggtgat gaaaagaatt gcagagatga
     2281 cagacatcaa gcccatcctg agaaaactgc cccggatcaa gaagtatcta ctaaactgtg
     2341 acaacatgag atgctcagtg aatgccaccc ctcagcagat gcctcaggca gaaaaagagg
     2401 tggaaaactt ccttagaaat gttggccgaa gcaaaaagga acggaagcct gtccgcccgc
     2461 atattgtcga gaaacccaca cccagtggcc ccagtggagc tgcacatgtc agtgggtccc
     2521 agatcgtcag aaaattggtg acagacccca ccttcaaacc ctgccagatg aagacacatt
     2581 ttgtgctgcc cttccctgtg aattacattg gcgagtgtgt caggactgtc ccgtatgctg
     2641 atccagacca tgccagcctt aagatccttg cccgtctaat gacagctaaa ttcttgcata
     2701 cggaaattcg agagaagggg ggtgcttatg gtggcggtgc taaactcacc cacagtggga
     2761 ttttcacgct ttactcttac agggatccca attccataga aacactccag tcttttggga
     2821 aagctgtaga ctgggctaag tctggaaagt tcacacagca ggacattgat gaagccaagc
     2881 tgtctgtttt ctctactgtg gattctcctg ttgctccatc cgataaagga atggaccact
     2941 tcttgtatgg cctctccgat gagatgaagc aggcataccg agaacagctc tttgctgtca
     3001 accacgacaa actgacctct gtgagccata aataccttgg catcgggaag agcacacacg
     3061 gcctggctat cctcggacca gagaactcaa aaattgccaa agacccatca tggatcataa
     3121 aataatgagt gccacatatc tttgagtatg tgtaagaaac cagaggctct taacagctga
     3181 gcctctgagc taaatttaat gcggatgatc acaagagtta ctagtttctt tgttcggaaa
     3241 atcagttagc catataaaaa ccaaccaaag gtgtttattg actggcaaaa actctgaagg
     3301 aaattctgag accatgaaga aatcattaat catgcattaa atgacagcag tgagcaaatt
     3361 aagcctctga aacattacta agcctagaat atgtatttta aatataaaag ccaactcc
//
