LOCUS       NM_025411               1554 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus PITH (C-terminal proteasome-interacting domain of
            thioredoxin-like) domain containing 1 (Pithd1), mRNA.
ACCESSION   NM_025411 XM_913437
VERSION     NM_025411.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1554)
  AUTHORS   Kondo,H., Matsumura,T., Kaneko,M., Inoue,K., Kosako,H., Ikawa,M.,
            Takahama,Y. and Ohigashi,I.
  TITLE     PITHD1 is a proteasome-interacting protein essential for male
            fertilization
  JOURNAL   J Biol Chem 295 (6), 1658-1672 (2020)
   PUBMED   31915251
  REMARK    GeneRIF: PITHD1 is a proteasome-interacting protein essential for
            male fertilization.
REFERENCE   2  (bases 1 to 1554)
  AUTHORS   Lu,B., Sun,X., Chen,Y., Jin,Q., Liang,Q., Liu,S., Li,Y., Zhou,Y.,
            Li,W. and Huang,Z.
  TITLE     Novel function of PITH domain-containing 1 as an activator of
            internal ribosomal entry site to enhance RUNX1 expression and
            promote megakaryocyte differentiation
  JOURNAL   Cell Mol Life Sci 72 (4), 821-832 (2015)
   PUBMED   25134913
REFERENCE   3  (bases 1 to 1554)
  AUTHORS   Li,H., Bishop,K.M. and O'Leary,D.D.
  TITLE     Potential target genes of EMX2 include Odz/Ten-M and other gene
            families with implications for cortical patterning
  JOURNAL   Mol Cell Neurosci 33 (2), 136-149 (2006)
   PUBMED   16919471
REFERENCE   4  (bases 1 to 1554)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY044314.1 and BC052695.1.
            
            On Oct 30, 2007 this sequence version replaced NM_025411.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF400670.1, AK004208.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               BY044314.1         1-100
            101-1554            BC052695.1         1-1454
FEATURES             Location/Qualifiers
     source          1..1554
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 68.34 cM"
     gene            1..1554
                     /gene="Pithd1"
                     /gene_synonym="1110049F12Rik; Trp26"
                     /note="PITH (C-terminal proteasome-interacting domain of
                     thioredoxin-like) domain containing 1"
                     /db_xref="GeneID:66193"
                     /db_xref="MGI:MGI:1913443"
     exon            1..307
                     /gene="Pithd1"
                     /gene_synonym="1110049F12Rik; Trp26"
                     /inference="alignment:Splign:2.1.0"
     exon            308..351
                     /gene="Pithd1"
                     /gene_synonym="1110049F12Rik; Trp26"
                     /inference="alignment:Splign:2.1.0"
     exon            352..429
                     /gene="Pithd1"
                     /gene_synonym="1110049F12Rik; Trp26"
                     /inference="alignment:Splign:2.1.0"
     exon            430..534
                     /gene="Pithd1"
                     /gene_synonym="1110049F12Rik; Trp26"
                     /inference="alignment:Splign:2.1.0"
     exon            535..643
                     /gene="Pithd1"
                     /gene_synonym="1110049F12Rik; Trp26"
                     /inference="alignment:Splign:2.1.0"
     exon            644..1538
                     /gene="Pithd1"
                     /gene_synonym="1110049F12Rik; Trp26"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1518..1523
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pithd1"
                     /gene_synonym="1110049F12Rik; Trp26"
                     /note="hexamer: AATAAA"
     polyA_site      1538
                     /gene="Pithd1"
                     /gene_synonym="1110049F12Rik; Trp26"
                     /note="major polyA site"
ORIGIN      
        1 ttttacgacg cctcggtggc ggcgcttggc ggtcgtcgcg gagccgagtg agctccgggt
       61 gagcggcggt gccgagggag tcacaggcga gccggcgggc ggcgtcgcca tgtcgcacgg
      121 ccacagccac ggcgggggcg gctgtcgctg cgccgctgag cgcgaggagc cgcccgagca
      181 gcgcggcctg gcctacgggc tgtacctgcg catcgacctg gagcgactgc agtgcctcaa
      241 cgagagccgc gagggcagcg gccgcggcgt cttcaagccg tgggaggagc ggaccgaccg
      301 ctccaagttt gttgaaagtg atgcggacga agagctcctg tttaatattc cgtttacggg
      361 caatgtcaag ctgaaaggcg tcatcataat gggcgaggat gatgactcgc acccctcgga
      421 gatgagactg tacaagaaca ttccacagat gtcatttgat gacacagaaa gggagccaga
      481 gcagaccttc agtctgaacc gagacattac aggagaatta gaatatgcta cgaaaatctc
      541 caggttttca aatgtctatc atctttccat tcatatttca aaaaactttg gagcagatac
      601 gacgaagatc ttttatattg gcctgcgggg agagtggact gagcttcgcc ggcatgaggt
      661 gaccatctgc aactatgaag cgtcagccaa cccagcagac caccgggtgc atcaggtcac
      721 cccgcagaca cacttcattt cttaagggcc agccggggct ccctcagatg cgctgttagt
      781 gaagatgtgc gaccacctgc tgggaaggac agaggatgct ccagcaagag ttgcctgcca
      841 gagctttggc caggctttgt ctcggggttg ctgcaggaac ctggcctgtg gaaaccgcct
      901 caccaccagg agcggtatgg gtgccaaggg atagtctctc tctaaggcac tgcagaaact
      961 gggtcttagg ctgggtggca tctgtcagtc atgaataatg ctcacttccc agtctgtggc
     1021 cacgggatcc catgtgtctt tttgcttgtg gcagatttct tgtgtggttt gtcctttttc
     1081 aaaaaggatg cttccttgac cgtaggaatc cttctgaaac ccgagtttcg tgtttgaatt
     1141 agccatcagg agggtctcca gctagaaaca cttcgtccct gcttgctcct cctcctgtca
     1201 ttgctcagca ttcgtgtcag ggtgcctagc tggtgtcaca tatcagacac aagtgtccca
     1261 caatggtggt tggaaaggaa ggagtctcct gatacatgac tgcttgggga aggtcttaca
     1321 cagtctagcc aaatagttgc gagtcctttc cctgtgtggg tgacctggtt ggggtaaaac
     1381 tgagacagta aagattcctc ttgggacctc cttggtgttt ccctgcttct aactcatgtt
     1441 ataaacccag ggctggagtc tggagaccct gctccttctg ttcatggctt tcattcatgg
     1501 tgactaatga gcttcctaat aaatccttag agacttaaaa aaaaaaaaaa aaaa
//
