LOCUS       NM_001418159            1700 bp    mRNA    linear   ROD 17-JUL-2024
DEFINITION  Mus musculus PICALM interacting mitotic regulator (Pimreg),
            transcript variant 3, mRNA.
ACCESSION   NM_001418159
VERSION     NM_001418159.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1700)
  AUTHORS   Hashimoto,K., Ohira,M., Kodama,A., Kimoto,M., Inoue,M., Tone,S.,
            Usui,Y., Hanashima,A., Goto,T., Ogura,Y., Ujihara,Y. and Mohri,S.
  TITLE     Loss of connectin novex-3 leads to heart dysfunction associated
            with impaired cardiomyocyte proliferation and abnormal nuclear
            mechanics
  JOURNAL   Sci Rep 14 (1), 13727 (2024)
   PUBMED   38877142
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1700)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1700)
  AUTHORS   Xu,Z.S., Zhang,H.X., Li,W.W., Ran,Y., Liu,T.T., Xiong,M.G.,
            Li,Q.L., Wang,S.Y., Wu,M., Shu,H.B., Xia,H. and Wang,Y.Y.
  TITLE     FAM64A positively regulates STAT3 activity to promote Th17
            differentiation and colitis-associated carcinogenesis
  JOURNAL   Proc Natl Acad Sci U S A 116 (21), 10447-10452 (2019)
   PUBMED   31061131
  REMARK    GeneRIF: regulates Th17 differentiation and colitis and
            inflammation-associated cancer by modulating transcriptional
            activity of STAT3
REFERENCE   4  (bases 1 to 1700)
  AUTHORS   Hashimoto,K., Kodama,A., Honda,T., Hanashima,A., Ujihara,Y.,
            Murayama,T., Nishimatsu,S.I. and Mohri,S.
  TITLE     Fam64a is a novel cell cycle promoter of hypoxic fetal
            cardiomyocytes in mice
  JOURNAL   Sci Rep 7 (1), 4486 (2017)
   PUBMED   28667270
  REMARK    GeneRIF: Expression of a non-degradable Fam64a mutant suggested
            that optimum Fam64a expression and subsequent degradation by
            anaphase-promoting complex/cyclosome (APC/C) during the
            metaphase-to-anaphase transition are required for fetal
            cardiomyocyte division. We propose that Fam64a is a novel cell
            cycle promoter of hypoxic fetal cardiomyocytes in mice.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1700)
  AUTHORS   Naiman,N., Fujioka,K., Fujino,M., Valerius,M.T., Potter,S.S.,
            McMahon,A.P. and Kobayashi,A.
  TITLE     Repression of Interstitial Identity in Nephron Progenitor Cells by
            Pax2 Establishes the Nephron-Interstitium Boundary during Kidney
            Development
  JOURNAL   Dev Cell 41 (4), 349-365 (2017)
   PUBMED   28535371
REFERENCE   6  (bases 1 to 1700)
  AUTHORS   Archangelo,L.F., Greif,P.A., Holzel,M., Harasim,T., Kremmer,E.,
            Przemeck,G.K., Eick,D., Deshpande,A.J., Buske,C., de Angelis,M.H.,
            Saad,S.T. and Bohlander,S.K.
  TITLE     The CALM and CALM/AF10 interactor CATS is a marker for
            proliferation
  JOURNAL   Mol Oncol 2 (4), 356-367 (2008)
   PUBMED   19383357
REFERENCE   7  (bases 1 to 1700)
  AUTHORS   Trimarchi,J.M., Stadler,M.B. and Cepko,C.L.
  TITLE     Individual retinal progenitor cells display extensive heterogeneity
            of gene expression
  JOURNAL   PLoS One 3 (2), e1588 (2008)
   PUBMED   18270576
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX119911.6.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.3217950.1,
                                           SRR13861894.2424288.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-266               BX119911.6         5025-5290
            267-587             BX119911.6         6001-6321
            588-865             BX119911.6         7965-8242
            866-961             BX119911.6         8663-8758
            962-1015            BX119911.6         9324-9377
            1016-1700           BX119911.6         9671-10355
FEATURES             Location/Qualifiers
     source          1..1700
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 43.81 cM"
     gene            1..1700
                     /gene="Pimreg"
                     /gene_synonym="2610008F03Rik; 6720460F02Rik; CATS; Fam64a"
                     /note="PICALM interacting mitotic regulator"
                     /db_xref="GeneID:109212"
                     /db_xref="MGI:MGI:1924434"
     exon            1..266
                     /gene="Pimreg"
                     /gene_synonym="2610008F03Rik; 6720460F02Rik; CATS; Fam64a"
                     /inference="alignment:Splign:2.1.0"
     exon            267..587
                     /gene="Pimreg"
                     /gene_synonym="2610008F03Rik; 6720460F02Rik; CATS; Fam64a"
                     /inference="alignment:Splign:2.1.0"
     exon            588..865
                     /gene="Pimreg"
                     /gene_synonym="2610008F03Rik; 6720460F02Rik; CATS; Fam64a"
                     /inference="alignment:Splign:2.1.0"
     exon            866..961
                     /gene="Pimreg"
                     /gene_synonym="2610008F03Rik; 6720460F02Rik; CATS; Fam64a"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1015
                     /gene="Pimreg"
                     /gene_synonym="2610008F03Rik; 6720460F02Rik; CATS; Fam64a"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1700
                     /gene="Pimreg"
                     /gene_synonym="2610008F03Rik; 6720460F02Rik; CATS; Fam64a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1677..1682
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pimreg"
                     /gene_synonym="2610008F03Rik; 6720460F02Rik; CATS; Fam64a"
                     /note="hexamer: AATAAA"
     polyA_site      1695
                     /gene="Pimreg"
                     /gene_synonym="2610008F03Rik; 6720460F02Rik; CATS; Fam64a"
                     /note="major polyA site"
ORIGIN      
        1 agtcccagcc tatcgctttg acaaaactac ttatcgtggg agagaagtta ggcggggtga
       61 aggactgaaa ggggcgcgtg ccctgggtgg cggtgacctg aacccccgca gcatcctgca
      121 ccctgacctg catgcttgaa gaagagagct tgggagaacg atggactagg cgcggtcgcc
      181 tgggaccaag cagccgggat gtagggaggc gggctggtcg gtaacagtga tccggtggcg
      241 acctggaccc ctctgcggcg agccaggatc tagcgggcag cggaaactgg accaagcaca
      301 tggcgtctca gtggcagggc atgaggacct ctgtgcgcag acgatcactc ctaaaggagg
      361 aacagctaga gaagaaggag gtgacccggt ctgctggggg tcatccggag accggtccct
      421 tgggctccct gtgcagacaa ttccaaagga ggctgcctct gagagcggtc agcctgaacc
      481 tcggtaacgg cccctcctgg aaacgcctgg aaagtccaga gccagagcag caaggtcttc
      541 aggctgcagc tcgctcagcc aaaagcgcct tgggtgccat gtcccagagg atccaggagt
      601 cctgtcagag tggcaccaag tggctgatgg agacacaggt gaaagtgaga aggaagcgag
      661 gagcccagaa agacagaggg tcaccaccac ccagtctgag ccagaagaac actcggctat
      721 gcagggccaa ccgggatgct agagtcgggg gacatcttcg cctctctggc cagatgggtc
      781 cgcatgccca tcgccgtcag cggctaagga gggagtctgc cctccggagc ccctgttcct
      841 ccacagaacc tctctgctct cccagtgagt ctgacagtga cctagagcct gtgggagccg
      901 gaatccagca tcttcagaag ctgtctcaaa ggctggacag agccatcaag gctgaagaga
      961 gtggtgacat gaccgtctcc cttatccgtg aatgaggaca gcaagcatcc tacaggaagc
     1021 cggctctgtc caaccaccaa gccaccagga tgtccatgct gcccaaccca tgaacttcct
     1081 ggagacagca ttgggtttat cagcatcccc aggccactgc taacaaggat ttgactaaca
     1141 tagggtccag aacccttcta cttcagccat atctgggccc actggtaacc actggccaca
     1201 gcctgagagt tatttaggaa gaccttgaag aggtgatggg aactgcccat gttcccccag
     1261 gggactcctg gactcgggca cacccatctg gctctccagc ttcatagttg tccatccata
     1321 ttaggaatgt accagaagat gctagatagt tctgagtctg gaaactagga ccaaggacct
     1381 gcaggagtca tcccacaaac cctccccctg tattcccagg gcagagattc cggaggaccc
     1441 actttcactg ctgcttccca cccccaggac cccacaggaa gagaggaggt atttgcagac
     1501 tgcaagcctc agctcacgga gcctacttat cttctccatg taggggcact agcgtgcctg
     1561 gaggggaatg ctgttcgaaa gcagtttctt ctctttgtaa attatttaag acatctgcta
     1621 tgtcattcta ttaaaaagat accagtgtgt catttgtagg tcacattgtt tttcgtaata
     1681 aaagctcgct ttccatgctt
//
