LOCUS       NP_001371131             224 aa            linear   ROD 09-JUN-2024
DEFINITION  paired immunoglobulin-like type 2 receptor beta-2 isoform 2
            precursor [Mus musculus].
ACCESSION   NP_001371131 XP_006504669
VERSION     NP_001371131.1
DBSOURCE    REFSEQ: accession NM_001384202.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 224)
  AUTHORS   Wilson,M.D., Cheung,J., Martindale,D.W., Scherer,S.W. and Koop,B.F.
  TITLE     Comparative analysis of the paired immunoglobulin-like receptor
            (PILR) locus in six mammalian genomes: duplication, conversion, and
            the birth of new genes
  JOURNAL   Physiol Genomics 27 (3), 201-218 (2006)
   PUBMED   16926269
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125063.4.
            
            On Jun 5, 2020 this sequence version replaced XP_006504669.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13861890.199564.1,
                                           SRR5189682.152943.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..224
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 76.85 cM"
     Protein         1..224
                     /product="paired immunoglobulin-like type 2 receptor
                     beta-2 isoform 2 precursor"
                     /note="paired immunoglobulin-like type 2 receptor beta-2;
                     activating receptor PILR-beta-2"
                     /calculated_mol_wt=22319
     sig_peptide     1..31
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=3137
     Region          40..134
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          56..60
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409377"
     Region          75..83
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409377"
     Site            90
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q2YFS1.1)"
     Site            107
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q2YFS1.1)"
     Region          115..119
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409377"
     Region          129..134
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409377"
     Site            160
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q2YFS1.1)"
     Site            196..216
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q2YFS1.1)"
     CDS             1..224
                     /gene="Pilrb2"
                     /gene_synonym="EG545812"
                     /coded_by="NM_001384202.1:106..780"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2"
                     /db_xref="GeneID:545812"
                     /db_xref="MGI:MGI:2450535"
ORIGIN      
        1 mallislpge tpamaqilll lssaclhagn sarsnggndf gvnqpercsg vqggsidipf
       61 sfyfpwklak dpqmsiawrw kdffghfiyn ssmpfihehf kgrlilnwtq gqtsgvlril
      121 nfkesdqtwy fcrvflqtte gikfwqslpg tqltltqaln ttmrspfivt sefttagleh
      181 trdkrnpslm nlgamvtmll akvvviilvy gwmiflrwkq rpah
//
