LOCUS       NM_207683               6280 bp    mRNA    linear   ROD 08-JUN-2024
DEFINITION  Mus musculus phosphatidylinositol-4-phosphate 3-kinase catalytic
            subunit type 2 gamma (Pik3c2g), transcript variant 1, mRNA.
ACCESSION   NM_207683 XM_001481182 XM_001481183 XM_001481184
VERSION     NM_207683.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6280)
  AUTHORS   Scortegagna,M., Berthon,A., Settas,N., Giannakou,A., Garcia,G.,
            Li,J.L., James,B., Liddington,R.C., Vilches-Moure,J.G.,
            Stratakis,C.A. and Ronai,Z.A.
  TITLE     The E3 ubiquitin ligase Siah1 regulates adrenal gland organization
            and aldosterone secretion
  JOURNAL   JCI Insight 2 (23), 97128 (2017)
   PUBMED   29212953
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6280)
  AUTHORS   Xing,Y., Morohashi,K.I., Ingraham,H.A. and Hammer,G.D.
  TITLE     Timing of adrenal regression controlled by synergistic interaction
            between Sf1 SUMOylation and Dax1
  JOURNAL   Development 144 (20), 3798-3807 (2017)
   PUBMED   28893949
REFERENCE   3  (bases 1 to 6280)
  AUTHORS   Braccini,L., Ciraolo,E., Campa,C.C., Perino,A., Longo,D.L.,
            Tibolla,G., Pregnolato,M., Cao,Y., Tassone,B., Damilano,F.,
            Laffargue,M., Calautti,E., Falasca,M., Norata,G.D., Backer,J.M. and
            Hirsch,E.
  TITLE     PI3K-C2gamma is a Rab5 effector selectively controlling endosomal
            Akt2 activation downstream of insulin signalling
  JOURNAL   Nat Commun 6, 7400 (2015)
   PUBMED   26100075
  REMARK    GeneRIF: PI3K-C2gamma-KO mice display reduced liver glycogen
            accumulation and develop hyperlipidemia, adiposity and insulin
            resistance with age or high-fat diet.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6280)
  AUTHORS   Mountford,J.K., Petitjean,C., Putra,H.W., McCafferty,J.A.,
            Setiabakti,N.M., Lee,H., Tonnesen,L.L., McFadyen,J.D.,
            Schoenwaelder,S.M., Eckly,A., Gachet,C., Ellis,S., Voss,A.K.,
            Dickins,R.A., Hamilton,J.R. and Jackson,S.P.
  TITLE     The class II PI 3-kinase, PI3KC2alpha, links platelet internal
            membrane structure to shear-dependent adhesive function
  JOURNAL   Nat Commun 6, 6535 (2015)
   PUBMED   25779105
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6280)
  AUTHORS   Pihlajoki,M., Gretzinger,E., Cochran,R., Kyronlahti,A., Schrade,A.,
            Hiller,T., Sullivan,L., Shoykhet,M., Schoeller,E.L., Brooks,M.D.,
            Heikinheimo,M. and Wilson,D.B.
  TITLE     Conditional mutagenesis of Gata6 in SF1-positive cells causes
            gonadal-like differentiation in the adrenal cortex of mice
  JOURNAL   Endocrinology 154 (5), 1754-1767 (2013)
   PUBMED   23471215
REFERENCE   6  (bases 1 to 6280)
  AUTHORS   Yu,W., Sun,X., Tang,H., Tao,Y. and Dai,Z.
  TITLE     Inhibition of class II phosphoinositide 3-kinase gamma expression
            by p185(Bcr-Abl) contributes to impaired chemotaxis and aberrant
            homing of leukemic cells
  JOURNAL   Leuk Lymphoma 51 (6), 1098-1107 (2010)
   PUBMED   20536348
  REMARK    GeneRIF: Data reveals that class II phosphoinositide 3-kinase gamma
            (PI3KC2gamma) expression is markedly down-regulated by
            p185(Bcr-Abl) but not p185(Delta176-426).
REFERENCE   7  (bases 1 to 6280)
  AUTHORS   Xu,H., Su,Z., Wu,J., Yang,M., Penninger,J.M., Martin,C.M.,
            Kvietys,P.R. and Rui,T.
  TITLE     The alarmin cytokine, high mobility group box 1, is produced by
            viable cardiomyocytes and mediates the lipopolysaccharide-induced
            myocardial dysfunction via a TLR4/phosphatidylinositol 3-kinase
            gamma pathway
  JOURNAL   J Immunol 184 (3), 1492-1498 (2010)
   PUBMED   20028656
  REMARK    GeneRIF: Lipopolysaccharide can induce high mobility group box 1
            (HMGB1) secretion by viable cardiac myocytes through a toll-like
            receptor 4/phosphatidylinositol 3-kinase gamma signaling pathway.
REFERENCE   8  (bases 1 to 6280)
  AUTHORS   Kamda,J.D. and Singer,S.M.
  TITLE     Phosphoinositide 3-kinase-dependent inhibition of dendritic cell
            interleukin-12 production by Giardia lamblia
  JOURNAL   Infect Immun 77 (2), 685-693 (2009)
   PUBMED   19047410
REFERENCE   9  (bases 1 to 6280)
  AUTHORS   Lee,A.W. and States,D.J.
  TITLE     Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism
            for proliferation and survival in myeloid cells
  JOURNAL   Cell Death Differ 13 (11), 1900-1914 (2006)
   PUBMED   16514418
REFERENCE   10 (bases 1 to 6280)
  AUTHORS   Misawa,H., Ohtsubo,M., Copeland,N.G., Gilbert,D.J., Jenkins,N.A.
            and Yoshimura,A.
  TITLE     Cloning and characterization of a novel class II phosphoinositide
            3-kinase containing C2 domain
  JOURNAL   Biochem Biophys Res Commun 244 (2), 531-539 (1998)
   PUBMED   9514948
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122511.5, AB008791.1, AK076317.1, AC174651.2, AC153381.2 and
            AC159545.18.
            
            On Feb 7, 2018 this sequence version replaced NM_207683.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC150813.1, AB008791.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849386
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-12                AC122511.5         47039-47050         c
            13-84               AC122511.5         44736-44807         c
            85-342              AC122511.5         42962-43219         c
            343-1096            AC122511.5         38557-39310         c
            1097-1179           AC122511.5         34544-34626         c
            1180-1337           AC122511.5         31247-31404         c
            1338-1452           AC122511.5         27331-27445         c
            1453-1555           AC122511.5         11891-11993         c
            1556-1584           AC122511.5         3933-3961           c
            1585-1875           AB008791.1         1600-1890
            1876-2575           AK076317.1         1545-2244
            2576-2604           AC174651.2         33357-33385
            2605-2793           AC174651.2         39873-40061
            2794-2887           AC174651.2         53846-53939
            2888-2982           AC174651.2         57565-57659
            2983-3163           AC153381.2         73996-74176         c
            3164-3271           AC153381.2         70395-70502         c
            3272-3364           AC153381.2         65182-65274         c
            3365-3494           AC153381.2         62667-62796         c
            3495-3631           AC153381.2         58563-58699         c
            3632-3801           AC153381.2         57682-57851         c
            3802-3958           AC153381.2         42605-42761         c
            3959-4068           AC153381.2         35989-36098         c
            4069-4258           AC153381.2         21809-21998         c
            4259-4380           AC153381.2         21215-21336         c
            4381-4489           AC153381.2         17680-17788         c
            4490-4565           AC153381.2         12-87               c
            4566-4660           AC159545.18        139015-139109
            4661-4786           AC159545.18        160739-160864
            4787-6280           AC159545.18        170824-172317
FEATURES             Location/Qualifiers
     source          1..6280
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 69.7 cM"
     gene            1..6280
                     /gene="Pik3c2g"
                     /gene_synonym="PI3K-C2-gamma"
                     /note="phosphatidylinositol-4-phosphate 3-kinase catalytic
                     subunit type 2 gamma"
                     /db_xref="GeneID:18705"
                     /db_xref="MGI:MGI:1203730"
     CDS             419..4939
                     /gene="Pik3c2g"
                     /gene_synonym="PI3K-C2-gamma"
                     /EC_number="2.7.1.137"
                     /EC_number="2.7.1.154"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ptdIns-3-kinase C2 subunit gamma; phosphatidylinositol
                     4-phosphate 3-kinase C2 domain-containing subunit gamma;
                     phosphatidylinositol 3-kinase, C2 domain containing, gamma
                     polypeptide; phosphatidylinositol 3-kinase C2
                     domain-containing subunit gamma"
                     /codon_start=1
                     /product="phosphatidylinositol 3-kinase C2
                     domain-containing subunit gamma isoform 1"
                     /protein_id="NP_997566.2"
                     /db_xref="GeneID:18705"
                     /db_xref="MGI:MGI:1203730"
                     /translation="MAYSWQTEPNRTEPQEDGSDTQQFHHTNQHLSSSQVRLGFDQLV
                     EEINNKTPLSESEKEEDTYFVPDAPNLGSKWPSIYETHPRYFSEFTSQSPDSSQLRFG
                     KLSAIGFNPAVLPTHQLIHEGASWRNPSGKYHGIEYPRFDALPPSSTGQGECNPQGQS
                     GTKHHNYCGEHEGNLPHHHSSYSIDSIPNREKRRSGDVNLVEPSLEFSKDSFLPRTSE
                     NVSVESTEPIGCPIEIVEVPQGSNKNLASFCNKVKKIRESYHASDINSNSGKIWAITT
                     AYPSRLFADTKFRVKISIDNSAQLLLLMPHANYLVKDLIAEILLLCANEPLSPKEYLL
                     SVCGSEEFLQMDHSLGGHKIFQKNKSVIQLHLQKNRDTPGKLSRKSEDDHSPFHLNQL
                     LEFTHIWKISRQCLSTVMKKYNLHVEHLLKPQKDMEEKHLSSMVSGNQHTSQPHVNNV
                     LEEVKNICSVLGCIETKQVSDAVKELNLILQRPSQNFHQNSETSKKGFIERVTAELSR
                     SIYQLIDVYCSTFCTDFQPVHTPGGVSRVHAGLQSHLSFTVCSLHNVPETWAHSYKAF
                     SFSCWLTYAGKKLCQVKSCRPLPVTKSFSLLVNWNEIINFPLEIKSLPRESMLIIKLF
                     GIDSATHSTNLLAWTCLPLFPRQESVLGSRLFSVTLQSEPPIEMIAPGVWDGSQPSPL
                     TLQIDFPDAGWEYLKPESEENRTDHEEPPRECLKHIAKLSQKKSPLLLSEEKRRYLWF
                     YRLYCNNENSSLPLVLGSAPGWDEETVSEMHAILRRWTFSHPWEALGLLTSRFPDQDI
                     REVAVQQLDTLLTDELLDCLPQLVQAVKFEWNLESPLVELLLRRSLQSIRVAHRLYWL
                     LRDAQGEAYFKSWYQELLAALQFCAGEALNEELSKEQKLVKLLGDIGEKVKSASDPQR
                     KDVLKKEIGSLEEFFKDIKTCHLPLNPALCIKGIDRDACSYFTSNASPLKITFINANP
                     MGKNISVIFKAGDDLRQDMLALQIIQVMDNAWLQEGLDMQMITYGCLSTGRAQGFIEM
                     VPDAVTLAKIHLHSGLIGPLKENTIKKWFSQHNHLKEDYEKALRNFFYSCAGWCVVTF
                     ILGVCDRHNDNIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEG
                     GKNTQHFQDFVELCCRAYNIVRKHSQLILSLLEMMLHAGLPELRGIEDLKYVHNNLRP
                     QDTDLEATSHFTKKIKESLECFPVKLNNLIHTLAQMPALSLAKPAPQTLLQESCILNK
                     TRTIQRVTILGFSKTHSNLYLMEVTCSDNRRSLTKKSFEQFYRLHSQMQKQFSSLALP
                     EFPHWWHLPFTDSDHKRIRDLSHYVEQVLRGSYEVANSDCVLSFFLSEHIQPTLEDSP
                     FVDPGENSLDKSPKVQLLMTYEDSRLTILVKHLKNIHLPDGSVPSAHVEIYLLPHPSE
                     VRRKKTKCVPKCTDPTYNEIVVYDEVLGLQGHVLMLIVKSKTVFVGAVNIQLCSVPLN
                     EEKWYPLGNSII"
     regulatory      6259..6264
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pik3c2g"
                     /gene_synonym="PI3K-C2-gamma"
                     /note="hexamer: AATAAA"
     polyA_site      6280
                     /gene="Pik3c2g"
                     /gene_synonym="PI3K-C2-gamma"
                     /note="major polyA site"
ORIGIN      
        1 aaacacatga atgtctttcc agaagccgtg ttatctgtga tgggtacatt ttctgcatcg
       61 ttcggaaaat acagaaggat tagtttgctg tgttaagtct cacagatggc catttaggaa
      121 taaagcattg gttttagctc acagttcaaa gcagagtcca tcatgattgg gagctgaggc
      181 aactcggcca caccccttcc acaagcaaca atggaaggat acataaatgg attctgcttc
      241 ttggatcctt ttctccaatt ctccaaagtt caataataat ccatttatgg aatggagcca
      301 cccacggtag gcgggaggtc ctcatcaatt agcacaacca aggaaaattt agaatttctt
      361 ttataatatc aagaagacat ttggagccaa ataaatcctc tgttacacaa aatcaaaaat
      421 ggcatacagt tggcaaacag agccaaatcg cactgaacca caggaagatg gatctgatac
      481 ccaacaattt caccatacaa accagcacct ttcttccagt caagtcaggt tgggttttga
      541 tcagctggtg gaagagatca ataataagac tccactgtct gagagtgaaa aggaagaaga
      601 cacgtatttt gtgccagatg caccaaactt gggttcaaaa tggccatcca tatatgaaac
      661 acacccaaga tacttcagtg aattcacttc tcagagccct gactcctccc agcttcggtt
      721 tggaaaacta tcagccattg gttttaatcc tgctgtacta ccaacccatc agctcattca
      781 tgagggagct tcctggagaa atcccagtgg aaaatatcat ggcatcgagt atcccagatt
      841 cgatgctcta cctccatcat ccactggcca gggtgagtgt aatccacaag gacaatcagg
      901 aaccaaacat cataactact gtggagaaca tgaaggcaat ctcccccatc atcattcatc
      961 ctactcaata gactccatac cgaatagaga gaaaagaagg agtggagatg tgaaccttgt
     1021 agaaccttct ctggagttct ctaaagactc ctttctaccc aggacatcgg agaacgtgtc
     1081 agtggaaagc acagagccga ttggttgtcc cattgaaata gttgaggtac cccaagggag
     1141 taacaagaac ctggcctcct tttgtaacaa agtaaaaaag ataagagaat cgtaccatgc
     1201 aagtgacatt aattccaatt ctgggaagat ctgggccatc accacagcct atccatctcg
     1261 gctcttcgct gacaccaaat tcagagtaaa aatttctatt gataactcag cccaactcct
     1321 ccttcttatg ccacacgcta attatcttgt caaagaccta attgctgaaa ttctactttt
     1381 atgtgcaaat gagccgcttt cccccaaaga gtatcttcta agtgtatgcg gttctgagga
     1441 atttttacag atggatcact ctctaggggg ccacaaaata ttccagaaaa ataaatctgt
     1501 cattcaactt catcttcaga aaaacaggga cactccagga aaattatccc ggaagagtga
     1561 agatgaccac agtccgtttc atctgaacca acttctagaa tttacacata tctggaaaat
     1621 atccagacaa tgcctctcca cagtaatgaa aaaatacaac ctccacgtgg aacacctgtt
     1681 gaaaccccag aaagacatgg aggagaaaca tttgtcgtcc atggtttctg gtaaccaaca
     1741 cacttctcag ccacatgtga ataatgttct tgaagaagtt aaaaacatat gcagtgtttt
     1801 ggggtgtatt gaaaccaaac aagtttcaga tgccgtgaaa gaactaaatc taattctgca
     1861 gagaccatca cagaattttc atcagaattc agagacttca aaaaaaggct tcatagagag
     1921 agtgacagct gaactatcaa ggtccatcta tcagctaatc gacgtgtact gcagtacctt
     1981 ctgtacagat ttccagcctg tgcacacacc cggaggtgtc tcccgtgtcc acgctgggct
     2041 ccagtcccac ctgagcttca cggtgtgttc cctgcacaat gtcccagaga cttgggcaca
     2101 cagctacaaa gcattttcgt tttcctgctg gctcacatat gctgggaaga agctgtgcca
     2161 agtgaaaagc tgcagacccc tgccagtcac aaagtcattc tcccttttgg tcaactggaa
     2221 tgaaataatc aattttcctc ttgagataaa gtcacttcca agagaatcca tgctcattat
     2281 aaaactgttc gggattgact ctgccaccca cagcacaaat ctgctggcct ggacctgcct
     2341 tccactgttt ccaagacagg agtctgtgct ggggtctagg ctgttcagtg tgacgttaca
     2401 gagtgagcct cctatcgaaa tgatagctcc aggcgtatgg gatgggagcc agccttcccc
     2461 actgaccctg cagatagatt ttccagacgc cgggtgggag tatctgaaac ctgagtctga
     2521 agagaacaga actgaccatg aagagccgcc aagagagtgt ttaaaacaca tcgccaaact
     2581 ctcccagaag aagtctccct tgctactttc tgaggaaaag aggagatatt tgtggtttta
     2641 tcgtctctac tgcaacaatg agaactcctc cctccctttg gtcttgggca gcgcccctgg
     2701 ttgggatgaa gagacagttt ctgaaatgca tgcaatcttg agaaggtgga cgttttcaca
     2761 cccatgggaa gctcttggtc ttttgacttc caggtttcca gaccaagaca ttcgtgaagt
     2821 tgccgttcaa caattagaca ccctcttgac tgacgagctg ctggactgcc tcccacagct
     2881 agtgcaggct gtcaagtttg agtggaacct cgaaagtccc ttggtggaac tcctgcttcg
     2941 tcgctccttg caaagcatcc gagtggctca ccgtctgtac tggctgctac gggatgccca
     3001 aggtgaagcc tactttaaaa gctggtatca ggagcttttg gccgctctcc agttctgtgc
     3061 aggagaagcc ctgaatgaag agctttccaa ggagcagaaa cttgtcaaac ttctgggtga
     3121 tattggagaa aaagtgaagt cagccagtga ccctcagaga aaggatgtgc taaagaaaga
     3181 gattggcagt ctagaagaat tctttaaaga tataaagact tgccatcttc ctctgaaccc
     3241 ggcactgtgc ataaaaggaa ttgatcggga tgcttgctcg tatttcacat ccaacgcttc
     3301 gccattgaag attactttca tcaatgctaa tccaatgggc aaaaatatca gtgttatttt
     3361 taaggccgga gatgatcttc ggcaggatat gcttgctctg cagattattc aagtgatgga
     3421 caacgcttgg ctgcaggagg gcctcgatat gcaaatgatc acttatggat gtctatccac
     3481 aggaagagcc caaggattca tagagatggt gcctgatgct gtaaccctgg ccaagatcca
     3541 tctgcactct gggctgatcg gacccctgaa agaaaacacc atcaagaagt ggttcagtca
     3601 gcacaaccac ttaaaggaag attatgagaa ggccttgagg aacttctttt actcttgtgc
     3661 tggctggtgt gtggtgacat tcatcttggg agtctgtgac cgacataatg acaatatcat
     3721 gctgacaaag tcaggtcaca tgtttcatat tgactttgga aaattcttgg gtcatgcgca
     3781 aacatttggc ggtatcaaaa gggacagagc ccctttcatt tttacttcag agatggagta
     3841 ctttattact gagggtggaa aaaacacaca gcattttcaa gacttcgtgg agctttgctg
     3901 cagagcttac aacatcgtca ggaaacacag ccagttgatc ctgagccttc tagagatgat
     3961 gctgcatgca ggactgcctg agctaagggg aatcgaagac ctgaagtatg tacataacaa
     4021 tcttcgccca caagacacag acctggaagc cacaagtcat ttcaccaaga agataaagga
     4081 aagtctggag tgtttcccag tgaaattgaa taacctgatc cacacacttg cacagatgcc
     4141 agccttaagc cttgccaaac ctgcccctca gactcttctc caggaatcct gcatcctgaa
     4201 taagaccagg acaattcaga gagtcacaat tttagggttc agcaagacac acagcaacct
     4261 gtacctgatg gaggtgacat gcagtgacaa taggagaagc ctgaccaaga agtccttcga
     4321 gcagttttac agacttcaca gccaaatgca gaagcagttc tcctccttgg ctctcccaga
     4381 atttcctcac tggtggcatc tacctttcac agactcagat cacaagagaa tcagagatct
     4441 gagtcactac gtggaacagg tgctacgcgg atcttatgaa gttgcaaaca gtgattgtgt
     4501 acttagcttt tttctctctg aacatattca accaacactt gaagactctc catttgtgga
     4561 cccaggtgag aactctctag acaagagccc taaggtgcag ttactgatga cgtatgagga
     4621 ctcgaggctc accatcctag tgaaacactt gaaaaacatc catctcccag atggctctgt
     4681 gcccagtgca catgttgaaa tttatcttct accacatccc agtgaagttc ggagaaagaa
     4741 aacaaagtgt gttccaaaat gcactgaccc aacttacaat gaaattgtgg tatatgatga
     4801 agtcttgggg ctccagggcc atgttttaat gcttatcgtg aagagcaaaa ctgtatttgt
     4861 gggagcagtt aacatccagc tctgcagtgt acccctcaat gaagaaaagt ggtacccact
     4921 aggaaacagt atcatctgac taacgccacg agcgtatgca ttactgctta agtacttgta
     4981 tgttttcagc ttctacttgc ctctgtcaca tatgcaaggc atctttctcc tgggagatag
     5041 cttcgagcag tggctctcag ccttcctaaa gctgtggccc tttaatatag ctcctggtgg
     5101 ttgtagtgac ccaaaccata aaattacttt agttgctact tcataattgt aattttgata
     5161 ctgttgtgaa ttgcaatgta attatctgat atacaggatc tctactatgt gacccatgtg
     5221 ataaaaggga catttgactc ccccaaaggg ccgtggccta tgggttgaga accatagaat
     5281 gtgaaggtta caaaagaacc agatcaaaat ctgccttttg tagctatttc ttccctatct
     5341 tgtccttatt ttcttatcat attttctcct tggaatatcc atcatgtaaa attccatatg
     5401 caaagtaatc aaagagtgat tattttcaat atgcattttg aaagcaacgt aagttcacat
     5461 tttgtcttaa ttgcttgttg aggtcaaaaa ttatattttc aaggtgtttc tctaaagctg
     5521 ggagaagttc atgaatgaat ctaaaggcta agaatacctg caatatattc caagcttaaa
     5581 tatgtgtaca aaccacatgt ctagtcatga gtggatttac tgagagaact ggtgatctcc
     5641 caccatatgc tataattttt ctatcaagaa aaggcctaag attttctatt acatagattt
     5701 ttttctttaa gaatttcatg cctatatata atgcctttca ttactctagt ttctctctgt
     5761 ttttgttgct cccacaccca tcaacaactg ttcttctcaa aaaaatcctg tattcctata
     5821 ggaaattttg tttttaagat gggaatcttg ctatatatcc tagctgacct agaacttact
     5881 atgtagacca agctgggccc aaaatcacag tggtcctcct gcctctgttt ccctatggct
     5941 gggactccaa atcattggtc ctgatctgta atctttaaat tcagttctta gaatttgatg
     6001 ttgactaatc cattgtcatt gtgtctccca gcctccaatg tgctcacacc ttaagtctta
     6061 ctaatcccaa actcagaatg tcagactttc aagttcactg tttataactc tttttcactt
     6121 gttaaatgct atcattgcac tcgaacctac cccctgttct caccatgaac agagtagatg
     6181 atcttacaga gtgttaccag catagtagac aaacccagag tagtgcgcct tcaagataat
     6241 caaactggag gttctaaaaa taaaacatct accatgtaaa
//
