LOCUS       NM_172822               2184 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus phosphatidylinositol glycan anchor biosynthesis, class
            Z (Pigz), mRNA.
ACCESSION   NM_172822
VERSION     NM_172822.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2184)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2184)
  AUTHORS   Rutkowski,T.P., Purcell,R.H., Pollak,R.M., Grewenow,S.M.,
            Gafford,G.M., Malone,T., Khan,U.A., Schroeder,J.P., Epstein,M.P.,
            Bassell,G.J., Warren,S.T., Weinshenker,D., Caspary,T. and
            Mulle,J.G.
  TITLE     Behavioral changes and growth deficits in a CRISPR engineered mouse
            model of the schizophrenia-associated 3q29 deletion
  JOURNAL   Mol Psychiatry 26 (3), 772-783 (2021)
   PUBMED   30976085
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124681.3.
            
            On Aug 1, 2009 this sequence version replaced NM_172822.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK089183.1, AK087516.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-193               AC124681.3         86536-86728
            194-387             AC124681.3         94598-94791
            388-2184            AC124681.3         96935-98731
FEATURES             Location/Qualifiers
     source          1..2184
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 22.4 cM"
     gene            1..2184
                     /gene="Pigz"
                     /gene_synonym="F630022B06Rik"
                     /note="phosphatidylinositol glycan anchor biosynthesis,
                     class Z"
                     /db_xref="GeneID:239827"
                     /db_xref="MGI:MGI:2443822"
     exon            1..193
                     /gene="Pigz"
                     /gene_synonym="F630022B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            194..387
                     /gene="Pigz"
                     /gene_synonym="F630022B06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             264..1946
                     /gene="Pigz"
                     /gene_synonym="F630022B06Rik"
                     /note="PIG-Z; GPI-MT-IV; GPI mannosyltransferase IV;
                     phosphatidylinositol-glycan biosynthesis class Z protein;
                     phosphatidylinositol glycan, class Z"
                     /codon_start=1
                     /product="GPI mannosyltransferase 4"
                     /protein_id="NP_766410.2"
                     /db_xref="CCDS:CCDS28109.1"
                     /db_xref="GeneID:239827"
                     /db_xref="MGI:MGI:2443822"
                     /translation="MMVAAQVIWGSFSLLRVLWCLLPQTGYIHPDEFFQSPEVMAEDI
                     LGVQATRPWEFYPSSSCRTVVFPLLTSGSTFWLLRLWEELGLWPGLVSGYMLLVGPRF
                     LLTALSFALDWAVYDLAPLWGADRWNALCLLSGSYVTLVFYTRTFSNTIEGLLFTWLL
                     VLVSPGVVRSPTSKKPTPGPRWHRYLLGVILAAGFFNRPTFLAFALAPLSLWGIHRAS
                     ELGGIRALIQEALVLLPGAALAAVLCVATDSWYFSSLSRSTGVFLTPANFLYYNLDPQ
                     NLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQQLHACLRASPQTGLSRVRGARGL
                     LSSSKSYLLLFYFTPLLLLSAFSHQEARFLIPLLVPLVLLCSPQTQPIPWKGTLVLFN
                     ILGALIFGCLHQGGLVPGLKYLEQIVHTPDLSGTTTHYTLLFTHTYMPPQHLLHLSGL
                     GSPVEVVDMGGAEDRVLCQALNNFSRQPACQLAGEPWPCRLFVVTPGTNRHALEKCRF
                     PLKNETLLFPHLTLEDPPALSSLLSGAWRKHLSLHVIELETPVVTKQPKAQP"
     exon            388..2184
                     /gene="Pigz"
                     /gene_synonym="F630022B06Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtagctagtt ctgcctgatc ccttggccta attccctggt tgaagtccag agtcggccgt
       61 ggagagggaa cgccatcgcc ccaccccgcc ctgcagccct ctgtcccgca ggcgcagggc
      121 gttagggccg cgggtgcagg ctttcgctcc aggcgaccag ggttgccagc gcggcaggtg
      181 cagcaccgct cggatgtaga tctttggact ggcacccgtg agaactgtga cagactttcc
      241 agtcctgtgc ctgacaactc gatatgatgg tggcagccca ggtgatttgg ggtagcttca
      301 gcctgcttcg tgtcttatgg tgtctccttc cccagactgg ctacatacac ccagatgaat
      361 tcttccagtc acctgaggtc atggcagagg acatcctggg tgtgcaggct acacggccct
      421 gggaatttta ccccagcagc tcctgccgca ctgtggtctt cccactgctg acctctggct
      481 ctaccttctg gttactcagg ctctgggaag agctggggct ctggcctggt ctggtgagtg
      541 gctacatgct gctggtgggg ccccgattcc ttctcaccgc cctctccttt gccctggact
      601 gggctgtgta cgatctggcc ccgttgtggg gggcagatcg ttggaatgcc ttgtgcctgc
      661 tgtctggttc ctatgtcacc ctggttttct acacaagaac cttctccaac accatcgagg
      721 gactgctctt cacctggctg ctggtgctgg tgtcccctgg tgtggtaagg agtcctacat
      781 caaagaagcc taccccaggt ccacggtggc acagatatct tcttggtgtt atcttggctg
      841 ctggcttctt caaccggcca acctttctag cctttgctct ggcccccctc tctctctggg
      901 gcatccatag agcttcagaa cttggtggca tcagggccct gatccaggag gccctggtgc
      961 tgttgccagg ggctgctctt gctgcagtgc tgtgtgtagc cacggacagc tggtacttct
     1021 ccagcctctc gagatccaca ggcgtctttc tcacacctgc caacttcttg tactacaacc
     1081 tggaccccca aaaccttgcc aggcacggca cacacgcacg gctcactcac ttggcagtca
     1141 atggcttcct gctctttggg gtgttgcatg ctcaagctct gcaggctgca tggcaacaac
     1201 tccacgcctg cctccgtgca tccccacaaa cgggtctctc cagggtgcgg ggtgcccggg
     1261 gtctgttgtc tagctccaag tcttatctcc tcctcttcta ctttacaccc ctgctcctgc
     1321 tttctgcctt cagccatcaa gaggctagat ttctgattcc cctcctagtc cctctagtcc
     1381 tgctgtgcag tccacaaacc caacctatac cctggaaagg caccctggtc ctcttcaaca
     1441 tcctgggcgc tctcatcttt ggttgcctgc atcagggagg tctggtaccg ggcctgaagt
     1501 acctggagca gatagtccac acgcctgacc tctcaggcac gaccacccac tacacacttc
     1561 tcttcacaca cacctacatg cctccccagc acctcttaca cctctcaggc ctgggatcac
     1621 ccgtggaggt ggtagacatg ggtggggctg aggacagggt cctgtgtcaa gccctgaaca
     1681 acttcagcag acaacctgcc tgccaactgg ctggtgagcc atggccctgt cggctctttg
     1741 tggtaactcc tgggaccaac aggcacgctc tggagaagtg ccgttttccc ctcaagaatg
     1801 agactctctt gtttccccac ttgaccctgg aggaccctcc agccctgtcc tctctgctca
     1861 gtggggcttg gaggaagcac cttagtctcc atgtcataga actggagacg cctgttgtga
     1921 caaagcagcc caaggctcag ccatagaagc cattccacct tctacacagg ctgctgggct
     1981 gggacattgg aacaggagcc ccgctgctct ctcttctggg cacagcctaa ggttgtttta
     2041 ggcgagccca cattcctctg ccttagacaa ccaaagatct gaccagtcat ggtctcaata
     2101 gcatgggcac ctgtctgctt ctatgccatt atttccaatc attgtcatgt ttaaaatata
     2161 tagtagcacc tggttatgaa agac
//
