LOCUS       NM_201406               2464 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus phosphatidylinositol glycan anchor biosynthesis, class
            S (Pigs), transcript variant 1, mRNA.
ACCESSION   NM_201406 XM_142436 XM_203412
VERSION     NM_201406.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2464)
  AUTHORS   Powles,N., Babbs,C., Ficker,M., Schimmang,T. and Maconochie,M.
  TITLE     Identification and analysis of genes from the mouse otic vesicle
            and their association with developmental subprocesses through in
            situ hybridization
  JOURNAL   Dev Biol 268 (1), 24-38 (2004)
   PUBMED   15031102
REFERENCE   2  (bases 1 to 2464)
  AUTHORS   Ohishi,K., Inoue,N. and Kinoshita,T.
  TITLE     PIG-S and PIG-T, essential for GPI anchor attachment to proteins,
            form a complex with GAA1 and GPI8
  JOURNAL   EMBO J 20 (15), 4088-4098 (2001)
   PUBMED   11483512
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591070.19.
            
            On Mar 17, 2023 this sequence version replaced NM_201406.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058979.1, AK166408.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                AL591070.19        21482-21544         c
            64-203              AL591070.19        21119-21258         c
            204-315             AL591070.19        20904-21015         c
            316-405             AL591070.19        16951-17040         c
            406-497             AL591070.19        16232-16323         c
            498-705             AL591070.19        14356-14563         c
            706-848             AL591070.19        13160-13302         c
            849-963             AL591070.19        12087-12201         c
            964-1109            AL591070.19        10502-10647         c
            1110-1210           AL591070.19        9881-9981           c
            1211-1421           AL591070.19        8555-8765           c
            1422-2464           AL591070.19        7214-8256           c
FEATURES             Location/Qualifiers
     source          1..2464
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 46.74 cM"
     gene            1..2464
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /note="phosphatidylinositol glycan anchor biosynthesis,
                     class S"
                     /db_xref="GeneID:276846"
                     /db_xref="MGI:MGI:2687325"
     exon            1..63
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..1697
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /note="isoform 1 is encoded by transcript variant 1; GPI
                     transamidase component PIG-S; phosphatidylinositol-glycan
                     biosynthesis class S protein; phosphatidylinositol glycan,
                     class S homolog"
                     /codon_start=1
                     /product="GPI transamidase component PIG-S isoform 1"
                     /protein_id="NP_958808.1"
                     /db_xref="CCDS:CCDS25100.1"
                     /db_xref="GeneID:276846"
                     /db_xref="MGI:MGI:2687325"
                     /translation="MAAAGAAATDLEVVRGKRSALFFAAVAILLGLPLWWKTTETYRA
                     PLPYSDISGLNALLLRLMVPVTVVFTRDSVPLDDQEKLPFTVVHEREIPLKYKMKIKC
                     RFQKAYRRALEHEEEALSLGSVHEAEAMLAEPEKQAEGSLTVYVISEHSSLLPQDMMS
                     YIGPERTAVVRGLIHREAFNIIGRRIVQVAQAMSLTEDVLAAALADHLPEDKWSSDKR
                     RPLKSSLGYEITFSLLNPDPKSHDVHWDIEGAVQRFVQPFLNRLSVAGNFSVDSQILY
                     YAMLGVNPRFDPASSSYSLAMHSLPHVINPVESRLGSSAASLYPVLHFLLYVPELAHS
                     PLYIQDKDGAPVATNAFHSPRWGGIMVYNVDPKIYNASELPVRVEVDMVRVMEVFLAQ
                     LRLLFGIAQPQVPPKCLLSGPKSEGLMTWELDRLLWARSVENLATATTTLTSLAQLLG
                     KISNIVIKDDVASEVYRAVAAVQKAAKALALGHLSSAFAASQEAVTSSERAFFDPSLL
                     HLLYFPDDQKFAIYIPLFLPMAVPILLSLVKIFQETRKSWKKPEKID"
     exon            64..203
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     exon            204..315
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     exon            316..405
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     exon            406..497
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     exon            498..705
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     exon            706..848
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     exon            849..963
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1109
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1210
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1421
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..2464
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2438..2443
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /note="hexamer: ATTAAA"
     polyA_site      2459
                     /gene="Pigs"
                     /gene_synonym="Gm393; Gm689"
                     /note="major polyA site"
ORIGIN      
        1 atcggcgacc tgggcagccg gaagggacca tggcggccgc aggagctgcg gccacggacc
       61 tagaggtggt ccggggcaag cgttccgcgc ttttcttcgc cgcggtggcc atccttctgg
      121 gactgccgct ctggtggaag acgacggaga cttaccgggc cccattgcct tactcagaca
      181 tcagtgggct gaatgctctg ctgctccggc tcatggtgcc agtcacagtt gtgtttactc
      241 gggactctgt gcccctggac gaccaagaga agctaccttt caccgttgtg catgagcgag
      301 agatccctct gaaatacaag atgaaaatca agtgccgttt ccagaaggcc taccggagag
      361 ctttggagca cgaggaggag gcgctgtccc tgggcagtgt gcacgaggca gaagccatgt
      421 tagctgagcc ggagaagcaa gctgagggct ccttgactgt gtatgtgatc tcggagcact
      481 cctcccttct tccccaggac atgatgagct acattgggcc tgagaggacg gcagttgtcc
      541 gggggctgat ccacagggaa gccttcaaca tcatcggccg tcgcatagtc caggtcgccc
      601 aggccatgtc cttgacggag gatgtgcttg ctgctgcctt ggccgaccac ctgcccgagg
      661 acaagtggag ctctgacaag aggcggccgc tcaagtccag cttaggctat gaaatcactt
      721 tcagtttact caacccagac cccaagtccc acgatgtcca ctgggacatt gagggagctg
      781 tccagcgctt tgtgcagcct ttcctgaatc gcctcagtgt tgcgggcaat ttctctgtgg
      841 actctcagat cctatactat gccatgctcg gcgtgaaccc ccgctttgac ccagcctcat
      901 ccagctactc cttggctatg cacagcctgc cccacgtcat caacccagtg gagtcccgac
      961 tcgggtccag cgctgcctcc ctgtaccctg tactccactt tctgctctat gtgcctgagc
     1021 ttgcccactc cccgctgtac attcaggaca aggacggagc tccagtggcc accaatgcct
     1081 tccacagtcc ccgctggggt ggcattatgg tatacaatgt tgatccgaag atctataatg
     1141 cttctgagct gccagtgagg gttgaggtgg acatggtgcg ggtgatggag gtattcctgg
     1201 ctcagctgag gctgctcttt ggaattgctc agccccaggt gcctcccaaa tgcctgctct
     1261 caggaccaaa gagtgaagga ctcatgacct gggagctgga ccgattgctc tgggctcgct
     1321 ccgtggagaa cctggccacg gccaccacca ccctcacctc cctggcccag cttctgggga
     1381 agatcagcaa cattgtcatc aaggatgatg tggcttctga ggtatatagg gctgtggctg
     1441 ccgtccagaa ggcagcaaag gccttagccc ttgggcacct gtcgtccgcc tttgctgcca
     1501 gccaggaagc cgtgacctcc tccgagcgcg ccttttttga cccctccctc ctccacctct
     1561 tgtatttccc cgacgaccag aagtttgcta tctacattcc cctcttcctg cccatggctg
     1621 tgcccatcct cctgtccctg gttaagatct ttcaggaaac tcgcaagtcc tggaaaaagc
     1681 ctgagaagat agactgatcc gggcagcatg tcagagggag ccctcctctc tagccacgct
     1741 gggagggtgt tgggccaaga gaccaaggca aggtctgctg gtgatgacat gtcttcactc
     1801 tcgcccgtgg gctctctacg gatggcactc cacgatgggc tcccttcccc tcctagtcca
     1861 ctggcttgct cctccatgcc tacaagcctc agaaggtacc cttcctgatc tccatatctg
     1921 gctcgaactt gaaagccttt gtgtgcctac ctctggacag gggtactttg tccttgcagc
     1981 ctgtcagcac agcatacaaa cgcactgaga ggtgaattta ggggagtact tgagttgaat
     2041 tgtagccctg tcctctccac ttctgagacc acctccctcc ttcctcagct tcttgactgg
     2101 cgtcacccac tggggacagc ctggtctagg aggcagtggc ttaggatctt ctaccttgtg
     2161 gctaaggttc ccctctaccc tttcagagag gtagtgtgga acaggagaaa acatttctga
     2221 cttggaaccc aacaggcctg aatcagactc cggcttctgc acttaacaga ctagagagca
     2281 tcagctaagc cgctcctcgc tcctcacctg agcctcaggt ttccattggt gggaaagcac
     2341 tgatgatgtc accctcagaa aggggctgga ttaaatgtga taagcctgta aaagtgttct
     2401 gtatattggg ctctttaaaa acatacatta gactgttatt aaacgttggt tgaatatgag
     2461 ttga
//
