LOCUS       NM_020035               4266 bp    mRNA    linear   ROD 17-DEC-2022
DEFINITION  Mus musculus phosphatidylinositol glycan anchor biosynthesis, class
            O (Pigo), transcript variant 1, mRNA.
ACCESSION   NM_020035
VERSION     NM_020035.3
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4266)
  AUTHORS   Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H,
            Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T,
            Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P,
            Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ,
            Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD,
            Flicek P, Skarnes WC, Mallon AM and Parkinson H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   2  (bases 1 to 4266)
  AUTHORS   Shishioh N, Hong Y, Ohishi K, Ashida H, Maeda Y and Kinoshita T.
  TITLE     GPI7 is the second partner of PIG-F and involved in modification of
            glycosylphosphatidylinositol
  JOURNAL   J Biol Chem 280 (10), 9728-9734 (2005)
   PUBMED   15632136
REFERENCE   3  (bases 1 to 4266)
  AUTHORS   Hong Y, Maeda Y, Watanabe R, Inoue N, Ohishi K and Kinoshita T.
  TITLE     Requirement of PIG-F and PIG-O for transferring phosphoethanolamine
            to the third mannose in glycosylphosphatidylinositol
  JOURNAL   J Biol Chem 275 (27), 20911-20919 (2000)
   PUBMED   10781593
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC092394.1 and BU708685.1.
            
            [WARNING] On Jul 26, 2023 this sequence was replaced by
            NM_020035.4.
            
            On Mar 10, 2015 this sequence version replaced NM_020035.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092394.1, AB038560.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4254              BC092394.1         1-4254
            4255-4266           BU708685.1         485-496
FEATURES             Location/Qualifiers
     source          1..4266
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4"
     gene            1..4266
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /note="phosphatidylinositol glycan anchor biosynthesis,
                     class O"
                     /db_xref="GeneID:56703"
                     /db_xref="MGI:MGI:1861452"
     exon            1..1212
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /inference="alignment:Splign:2.1.0"
     CDS             678..3983
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /note="isoform 1 is encoded by transcript variant 1; GPI
                     ethanolamine phosphate transferase 3;
                     phosphatidylinositol-glycan biosynthesis class O protein"
                     /codon_start=1
                     /product="GPI ethanolamine phosphate transferase 3 isoform
                     1"
                     /protein_id="NP_064419.2"
                     /db_xref="CCDS:CCDS18088.1"
                     /db_xref="GeneID:56703"
                     /db_xref="MGI:MGI:1861452"
                     /translation="MNILFSPRMRKVSVLLFLAWVCFLFYAGIALFTSGFLLTRLELT
                     NQSSCQELPGPGPLPWGSHGKPGACWMPSRFSRVVLVLIDALRFDFAQPQRSHVPGEP
                     PVSVPFLGKLGSLQRILESQPHHGRLYRSQVDPPTTTMQRLKALTTGSLPTFIDAGSN
                     FASHAIVEDNVIQQLNSAGRRVVFMGDDTWRDLFPGAFSQAFFFSSFNVRDLHTVDNG
                     ILEHLYPTLDGGSWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLIERLEN
                     DTLLVVAGDHGMTMNGDHGGDSELEVSAALFLYSPTALFPSVPPEEPEVIPQVSLVPT
                     LALLLGLPIPFGNTGEVMAELFSGGSDSSHPHSSALAQVSALHINAQQVSRFLHTYSA
                     ATQDLQVKELHRLQTLFSKASARYQHFLRDPQEAEAALSTLTAEFQQFLRGARALCIE
                     SWARFSLVRMAGGAALLAAACLLCLLASQLAVAPGFLFRPLLLIPVAWGLTWTILYAG
                     VSVTTGSKIDLVVLGAVAAAGSLLPFLWKAWVSRGSKRPLAPLLPVPRPVLILLLIRL
                     ATFFSDSFVVAEARATPFLLGSLVFFLVAQLHWEGQLLPPKPLTMSRLGSSAPTAPPR
                     HSGAHALWLGIGLLLFTRLAGLFHRCPEETPACRSSPWLSPLASMVGGRAKNLWYGAC
                     VGALVALLVVVRLWLRRYGNLKSPEPPVLFVRWGMPLMVLGTAAYWALASGAEEAPPR
                     LRALVAGASAVLPRAVMGLAALGLVLLLWRPVTVLVKAGAATSRTRTILTPFSGPPTS
                     QADLDYVVPQIYRHMQEEFQGRLERTKAQGPITVAAYQLGSVYSAAMVTALLLLAFPL
                     MLLHVERVSLVFLLLFLQSFLLLHLLAAGTPVATPGPFTVLWQAVSAWVLLATQTFYS
                     TGHQPVFSAIHWHAAFVGFPDGHGSSTWLPALLVGANTFASHLLFAVGCPLLLLWPFL
                     CERQGPKRRQPLPGSESEARVRPEEEEELQEPLMEMRLRDAPNHFNAALLQLGLKYLF
                     ILGAQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIALVMRVDVAV
                     SSWFKKLVLAQQR"
     exon            1213..1356
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1480
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1640
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /inference="alignment:Splign:2.1.0"
     exon            1641..1823
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /inference="alignment:Splign:2.1.0"
     exon            1824..3351
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /inference="alignment:Splign:2.1.0"
     exon            3352..3558
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /inference="alignment:Splign:2.1.0"
     exon            3559..3782
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /inference="alignment:Splign:2.1.0"
     exon            3783..3853
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /inference="alignment:Splign:2.1.0"
     exon            3854..4266
                     /gene="Pigo"
                     /gene_synonym="PIG-O"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccaaggtctc cctgttacct ctgttactgt cacccctagg acgggtgtct cagcttactg
       61 ccggggtgcc cagtatcaga gggagcatgt ccaggtgttg gccgggttcc caccggagga
      121 gacagagctg ccgggacttc tggatcccag cttagctcaa tgggctttat accgggcttc
      181 ctggggacgt cgttccttcg gttttttctt gagcctggcc gcccggaagc ggagcaagac
      241 tcctccccgt cgtttcctcg gttcccgcca ggcggcgccg tttactcaat ccagttaatc
      301 cgtgtggttt ctgtctattg ccaccctgga aatgttgagt tagtccgaag agagccattg
      361 aaatggactg tcagagaaca atctacctac catttggaat agtcttcctc ctagactgtg
      421 gtttgacagc attagatctc ccggttggat atgcacaggc tcccgtgctc acccccagaa
      481 cctgaatcgg taggtgtagc ctgggcgtca ggttgagatc caaggtctca gcctctcacc
      541 gtcagatggt atgactggta gaaacagctg caacgagtta gctatggttt gtttacgtcc
      601 tgaagtttat agcagtacgt gattgttgtt gggcattgtt ttgagagcca aaacgtccat
      661 ggtttcttcg caccccaatg aacattctct tctctcccag gatgcggaag gtgtctgtgc
      721 tcctcttctt agcctgggtc tgttttcttt tctacgctgg cattgcactc ttcaccagtg
      781 gcttccttct cactcgtctg gagctcacca atcaaagcag ctgccaagag ctcccaggcc
      841 ctggtccctt gccgtgggga agtcatggaa agcctggggc ttgctggatg ccttcccgct
      901 tctccagggt ggttttggta ctgatagacg ctctgcggtt tgactttgcc cagcctcagc
      961 gctcgcatgt gcctggggaa cctcctgtct ccgtgccttt tctgggaaaa ttaggttcct
     1021 tgcagaggat cctagagagt caaccccacc atggccggct gtaccgatct caggtggacc
     1081 cccccacgac caccatgcag cgtctaaagg ctctcaccac tggctcgctg ccgactttca
     1141 ttgatgctgg cagtaacttt gccagccatg ctatagtgga agataatgtc atccaacagc
     1201 tcaacagtgc aggaaggcgt gtagtcttca tgggagatga tacctggaga gacctcttcc
     1261 ccggagcctt ttctcaagct ttcttcttct catccttcaa tgtcagagac ctgcacacag
     1321 tggataacgg catcttggaa cacctctatc ctaccctgga cggcggttcg tgggatgtgc
     1381 tgatcgctca cttcctgggt gtggatcact gtggtcacaa gcacggccct caccaccctg
     1441 aaatggccaa gaaacttagc cagatggacc aggtgataca gggactcata gaacgcctgg
     1501 agaatgacac actgctggtg gtagccggtg accatgggat gaccatgaat ggggaccatg
     1561 gaggggacag tgagctggag gtgtcagctg cacttttcct gtacagcccc acagctctct
     1621 tccctagtgt cccacccgag gagccggagg ttattcctca ggtcagcctt gtgcccacgc
     1681 tggcactgct gctaggcctg cccatcccgt ttgggaacac tggggaagtg atggcagagc
     1741 tattctcagg tggcagtgac tcctcccatc ctcactcctc tgcgctagcc caagtctcgg
     1801 ctctccacat caatgcccag caggtgtccc ggtttcttca tacctactcg gctgcgactc
     1861 aggatctcca agttaaagaa cttcatcggc tgcagacgct cttctccaag gcctctgcgc
     1921 gttaccagca ctttctgcgg gatccccaag aggctgaggc agcgctgagc acattgactg
     1981 ctgagttcca gcagttcctg cggggagctc gggccctgtg catcgagtct tgggcccgct
     2041 tctctctggt ccgaatggca gggggcgctg ctcttttggc tgctgcctgc cttctctgcc
     2101 tgcttgcttc ccagttggca gtcgccccag gctttctctt ccgcccacta ctgctaatac
     2161 ctgtagcctg gggcctaact tggaccatcc tgtatgctgg agtctcggta actactgggt
     2221 cgaagataga cttagtggtt ctgggggctg tggctgcagc cggttcactc ctcccttttc
     2281 tgtggaaagc ttgggttagc agggggtcta agaggccact ggctccccta cttcctgtcc
     2341 ctagacctgt cctaatatta ctgctcattc gcttggccac cttcttctcg gatagctttg
     2401 ttgttgctga ggccagggcc acccccttcc ttctgggctc tctcgttttc ttcctggttg
     2461 ctcagctcca ctgggagggt cagctactgc cacccaaacc actcacgatg tcccgccttg
     2521 gctcttctgc cccaacagcg cccccacggc acagtggcgc gcatgccctg tggcttggaa
     2581 ttgggttgct tttatttaca aggctcgctg ggctttttca ccgctgcccg gaagagacac
     2641 ctgcctgtcg ctcctctccc tggctgagtc ctctggcatc tatggtggga ggtcgagcca
     2701 agaatttgtg gtacggagct tgcgtggggg cactggtggc cctgttagtc gtcgtgcgct
     2761 tgtggcttcg ccgctatggt aatctcaaga gtcctgagcc ccctgtgctc tttgtgcgct
     2821 gggggatgcc tctcatggta ctgggcacgg ctgcctactg ggcactggca tcaggtgcag
     2881 aggaagcacc accacgcctc cgggccctgg tcgccggggc atcagctgtg ctgcctcggg
     2941 ctgtgatggg gctggctgcc ttggggctcg tgctgctgct ctggaggcct gtgacagtgc
     3001 tggtgaaagc tggggctgct acttcaagga ccaggactat cctcactccc ttctcaggtc
     3061 cccctacttc tcaggctgac ctcgactatg tagtcccaca aatctaccgc cacatgcagg
     3121 aggagttcca gggccggctc gagaggacta aagctcaggg tcccataacc gtggctgcct
     3181 atcagttggg aagcgtgtac tcggctgcta tggtcacggc cctcctcctc ttggccttcc
     3241 cacttatgct gttgcatgta gagcgggtca gcctggtgtt cctgctcctg tttctgcaga
     3301 gcttccttct cctgcatctg ctggccgctg ggacaccagt cgccacccct ggccctttta
     3361 ctgtgctgtg gcaggcagtc tcagcttggg tccttctggc tacccagacc ttctactcca
     3421 caggccacca gcctgtcttt tcagccatcc attggcacgc agcctttgtg ggcttcccag
     3481 acggccatgg ctcttctacc tggttgcctg ccttactagt gggagctaac acctttgcct
     3541 cccacctcct cttcgcagta ggctgcccac tgctcctgct ctggcccttc ctgtgtgagc
     3601 gtcaagggcc aaagagaagg cagcccctcc cgggaagtga gtctgaagcc agagtccggc
     3661 ctgaggaaga ggaggagctg caggagccac tgatggagat gcgcctccgg gatgctccga
     3721 atcacttcaa tgcagccctg ttgcagctgg gcctcaagta cctctttatc cttggagctc
     3781 agattctagc ttgtgccttg gcagcttcca tcctccgcag gcacctcatg gtctggaagg
     3841 tgtttgctcc caagttcatt tttgaagccg taggtttcat cgtgagcagt gtgggacttc
     3901 tcctgggcat agcattggtg atgcgagtgg atgtcgctgt gagttcctgg ttcaaaaaac
     3961 tagttctggc ccagcagagg tagcccaggc tgtgctcgtt ggcgtctggc catggagaga
     4021 gctggggact aatccggcct gacctgtact ggtgctggat tctgcaagag actccgacac
     4081 acctcttgag ccaccctgta accagagact gctcaactct gggactttat tattttataa
     4141 ctgagaatca tctggagccc gagcccgagc ccgagccttc cctcctgggt tggatacatc
     4201 tgacggacaa caggggcggc taccaaagtg gaataaaaga acaatgtgaa tgttttatgt
     4261 agctaa
//
