LOCUS       NM_001039045            3288 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus phosphatidylinositol glycan anchor biosynthesis, class
            C (Pigc), transcript variant 2, mRNA.
ACCESSION   NM_001039045
VERSION     NM_001039045.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3288)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ171161.1, AK152660.1 and CAAA01056494.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK161117.1, SRR1660815.259761.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                CJ171161.1         1-10
            11-1476             AK152660.1         2-1467
            1477-3288           CAAA01056494.1     32554-34365
FEATURES             Location/Qualifiers
     source          1..3288
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 69.95 cM"
     gene            1..3288
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
                     /note="phosphatidylinositol glycan anchor biosynthesis,
                     class C"
                     /db_xref="GeneID:67292"
                     /db_xref="MGI:MGI:1914542"
     exon            1..92
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            93..3288
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             304..1197
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
                     /EC_number="2.4.1.198"
                     /note="PIG-C; phosphatidylinositol-glycan biosynthesis
                     class C protein"
                     /codon_start=1
                     /product="phosphatidylinositol
                     N-acetylglucosaminyltransferase subunit C"
                     /protein_id="NP_001034134.1"
                     /db_xref="CCDS:CCDS15419.1"
                     /db_xref="GeneID:67292"
                     /db_xref="MGI:MGI:1914542"
                     /translation="MCAQRVTDTPEVKWQKVLYERQPFPDNYVDQRFLEELRKNIYAR
                     KYQYWAVVFESSVVIQQLCSVCVFVVIWWYMDEGLLAPQWLFGTGLASSLVGYVLFDL
                     IDGGDGRKKSGRTRWADLKSTLVFITFTYGFSPVLKTLTESVSTDTIYAMAVFMLLGH
                     LIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFIMVTFAIQIFALWPMLQK
                     KLKAYTPRSYVGVTLLFAFSAFGGLLSISAVGAILFALLLFSISCLCPYYLIHLQLFK
                     ENIHGPWDEAEIKEDLSRFLS"
     regulatory      1459..1464
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1477
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
                     /note="major polyA site"
     regulatory      2629..2634
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
                     /note="hexamer: TATAAA"
     polyA_site      2651
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
     regulatory      2746..2751
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2769
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
     regulatory      2993..2998
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
                     /note="hexamer: CATAAA"
     polyA_site      3013
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
     regulatory      3069..3074
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3099
                     /gene="Pigc"
                     /gene_synonym="3110030E07Rik"
ORIGIN      
        1 agtagtcccc ttccaagccg gcgtcccgga tgtagaagta gctaggcggc cgctcttctc
       61 ggtcgtgcac ccccctaaag agcttggtgc aggaatttag ctgtgttgtc ctgaccctca
      121 ggacaaactc atctaatgca ggctcagctt gtactgaagg ctttgtaaac aaggaaagtt
      181 ctgtagggta tcagcatggc atttccagag agttcttaat ctacagattt atcaagaacc
      241 agaaccccat ggacgtccct gagggagatt gagccaacct ggatttgagg aaagaatgag
      301 ataatgtgtg ctcaacgtgt aacagacacc ccagaagtca agtggcagaa ggttttatat
      361 gagcggcagc cgttccctga taactatgtt gaccagaggt tcctggaaga actccggaaa
      421 aacatctatg cccggaagta ccagtactgg gctgtggtat ttgagtccag tgtggtgata
      481 cagcagctgt gcagtgtctg tgtttttgta gtgatctggt ggtacatgga tgagggtctt
      541 ctggctcccc agtggctttt tgggaccgga ctggcatctt ccttggttgg gtatgtttta
      601 ttcgatctta tcgatggagg tgatggacgg aagaagagtg ggcggacccg gtgggccgac
      661 ctgaagagta ctctggtctt tatcactttc acttacggtt tttcacctgt gctaaagacc
      721 ctgacggagt ctgtcagtac agacactatc tacgccatgg cagtctttat gctgttaggc
      781 catctcatct tctttgatta cggtgccaat gctgctattg tatccagcac cctgtccttg
      841 aacatggcca tctttgcttc tgtttgcctg gcctcacgcc tcccccggtc actccacgcc
      901 ttcattatgg tgacgtttgc tatccagatc tttgcactgt ggcccatgtt acagaagaaa
      961 ctgaaggcgt acaccccgcg aagctatgta ggggtcactt tgctttttgc cttttctgcc
     1021 tttggaggtc ttctgtccat tagtgctgtg ggagccatac tctttgctct cctgctgttt
     1081 tccatctcct gtctctgccc ttactacctc attcatctgc agctttttaa ggaaaatatt
     1141 cacgggcctt gggatgaagc tgaaatcaag gaagacttgt ctaggttcct tagctaatct
     1201 agggaccttc atttcattat taagaccagc ggaaagactt cgagcctaac cggtgcaaca
     1261 tttaaaggca ggggtccact cttgaagcag ccgactgatc tagatggtag agctgagatc
     1321 agaagaaagc atttaaccaa gggcttaggg gagggtgctt gtccttcagt tattttgtga
     1381 ctgaaaaagc tttctggtgc tgttatgaat tattgtcctt tattccctgt aacaaatgat
     1441 gtaatgtggg ttctgcttat taaaaaagta atatccattg cattgtctag tattttaaaa
     1501 aaaacaaaac aaggaaaccc ttatttatgt gtgtataaga gagggggttt gtctatttcc
     1561 agtatgtatg tcccacgcat caaattcagg ccctggcaac aggcctttac cagctgagcc
     1621 atcacactgg ccctgtctca tttttatgag agcataagac aaaagtagta tgaaggtgtg
     1681 tgtgtgtgtg taaaagtgta atcagttgtt tagccttttc tgtgtatact aagggacacc
     1741 tttatatatc tagagcccaa atttgagaat ccctgatggt ggcatccagt ttgttgtcca
     1801 ataccacaga agtggtcact caaggagagc tacatgccat agaaacaaaa cgttagcgat
     1861 atgaaagagg ctggagggtg agttcatctc aggcagttag gaaaccagag gtgacattta
     1921 atttactcgt ggaggatagc aggtgaaagc ctttgagaaa cagataggta atactagtga
     1981 gaatggaaaa ctatggacca agcaagtgtg cccagtgagg gcagctgtta ccgctccaaa
     2041 agtgttgttt ctactcagtt tgggagtcat acctgtggct cagagaaagt aaatattgca
     2101 gtaactgtga ttctgattcg taatatgaat atactttgtg aactgtctca aatttaattc
     2161 agattacaaa aacatttgca ggcaagatgt gactacatat gatagtcaaa gcacaatgat
     2221 gggaacgtga tgggatttag tcacagagat ctgggggagg aacgaaagag tgggagcttg
     2281 agtcactgag ttcggctctg ttgatcaagt aattggaccc tgctgctggt gatgagcaat
     2341 ccatcttgtc taaagatggg acaaattgtg aagtctggaa ttacctaacc gttcagttct
     2401 cagctttcac ctttaatatt gaagaattgt tgcaatagat aagctgtgtg aagcgtcttg
     2461 aagagagccc aacccgaagc tcgatgttag tgctgagcac ctcaaatgca aaattctgaa
     2521 atctgaaatg ctccaggatc tgctctgaaa ggttttgagc accaatgcta tgccctgtga
     2581 aaattctaca ttctattcca tgaaatctgt gcaaaactat ttaagaagta taaaactgtc
     2641 ttaatatggt atataagttg tatatgaagt aattaagtct tatgtttaga tgggtcctgt
     2701 tctcaagcta tctctatgta aaaatttcaa aatctgaggg aaaaaattaa aaatgttttt
     2761 ggtattggat aagggacatt ggaggtgtca taacagttgg aatgtaggtt aaatttgaag
     2821 agggcaaagg cacaaaatga atgaggtact ttctccagtg gctgcttcca tctgtgcaag
     2881 tggtacttgc cctctgcttg ttgtaagtag tctcaaatta gaactaacaa gcgggtagta
     2941 gtatagcata ttactatact gtgaagtaat cctttttatt tttctggttt ctcataaaaa
     3001 tcttgacgag gaatttcaac taatgccatt tttttatgtt tactgttatt gatgaagatt
     3061 gtttcatgat taaaaaaaaa gtgggttatt gtcccccaag atcacttacc ctgctttctc
     3121 aaacccacgg gcacttggtt tgggggggaa aagacaaaga actgccccat ggagcccaaa
     3181 gcatccaggc attgcctgtg atggattgta cacattgtgt ctccaaattg gcacgaatta
     3241 ttcatcgttc acatcaacgg atggcagttg gatgtaaaaa ggtattgt
//
