LOCUS       NM_178621               2873 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus phytanoyl-CoA hydroxylase interacting protein-like
            (Phyhipl), transcript variant 1, mRNA.
ACCESSION   NM_178621
VERSION     NM_178621.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2873)
  AUTHORS   Sugimoto,H., Horii,T., Hirota,J.N., Sano,Y., Shinoda,Y., Konno,A.,
            Hirai,H., Ishizaki,Y., Hirase,H., Hatada,I., Furuichi,T. and
            Sadakata,T.
  TITLE     The Ser19Stop single nucleotide polymorphism (SNP) of human PHYHIPL
            affects the cerebellum in mice
  JOURNAL   Mol Brain 14 (1), 52 (2021)
   PUBMED   33712038
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2873)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK032166.1, AK029522.1 and AC122896.4.
            
            On Jul 1, 2009 this sequence version replaced NM_178621.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029522.1, AK032166.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1958              AK032166.1         2-1959
            1959-2673           AK029522.1         1946-2660
            2674-2674           AC122896.4         93621-93621         c
            2675-2873           AK029522.1         2662-2860
FEATURES             Location/Qualifiers
     source          1..2873
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 36.69 cM"
     gene            1..2873
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /note="phytanoyl-CoA hydroxylase interacting protein-like"
                     /db_xref="GeneID:70911"
                     /db_xref="MGI:MGI:1918161"
     exon            1..287
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /inference="alignment:Splign:2.1.0"
     CDS             185..1312
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="phytanoyl-CoA hydroxylase-interacting
                     protein-like isoform 1"
                     /protein_id="NP_848736.2"
                     /db_xref="CCDS:CCDS23914.1"
                     /db_xref="GeneID:70911"
                     /db_xref="MGI:MGI:1918161"
                     /translation="MEVPRLDHALSSPSSPCEEIKNLSLEAIQLCDRDGNKSQDSGIA
                     EMEELPVPHNIKINNITCDSFKISWDMDSKSKDRITHYFIDLNKKENKNSNKFKHKDV
                     PTKLVAKAVPLPMTVRGHWFLSPRTEYTVAVQTASKQVDGDYVVSEWSEIIEFCTADY
                     SKVHLTQLLEKADVIAGRMLKFSVFYRNQHKEYFDYVREHYGNAMQPSIKDNSGSHGS
                     PISGKLEGIFFSCSTEFNTGKPPQDSPYGRYRFEIAAEKLFNPNTNLYFGDFYCMYTA
                     YHYVILVIAPVGSPGDEFCKQRLPQLNSKDNNFLTCTEEDGVLVYHHAQDVILEVIYT
                     DPVALSLGTVAEITGHQLMSLSTANAKKDPSCKTCNISVGR"
     exon            288..484
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /inference="alignment:Splign:2.1.0"
     exon            485..659
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /inference="alignment:Splign:2.1.0"
     exon            660..777
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /inference="alignment:Splign:2.1.0"
     exon            778..2873
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1659..1664
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /note="hexamer: AATAAA"
     polyA_site      1682
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /note="major polyA site"
     regulatory      1821..1826
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /note="hexamer: AATAAA"
     polyA_site      1841
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
     regulatory      2002..2007
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /note="hexamer: ATTAAA"
     polyA_site      2024
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
     regulatory      2281..2286
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
                     /note="hexamer: AATAAA"
     polyA_site      2300
                     /gene="Phyhipl"
                     /gene_synonym="4921522K17Rik; PHY2"
ORIGIN      
        1 agtctacgag ccgcgcactc gaaggagctt ctgccgccgc tgccgccgcc gccaccacca
       61 ccgccgccgc cgcctcggcc gcgactcccg accggaggtt gccctcgtcc tcagccttct
      121 caggcctttc ccgcccttcg ccccgccggc cgctggcgcc tggcttcgac gcggggtcgc
      181 gaagatggag gtgccgcgcc tggaccatgc cctcagcagc cccagtagtc cgtgtgagga
      241 gatcaagaac ctcagcctgg aggccatcca gctgtgcgac cgtgatggta acaaatcaca
      301 agacagtggc atagcagaga tggaagagct acctgtccca cataacatca aaataaataa
      361 catcacatgt gactccttca agatctcatg ggatatggac tccaagtcga aggaccgcat
      421 cacgcactac ttcattgacc tcaacaagaa agagaacaag aactcgaaca agtttaaaca
      481 caaggatgtt ccaacaaaat tggtggccaa agctgttcct ttgccaatga ctgttcgtgg
      541 acactggttt ttgagcccaa ggactgagta tacagtagcg gtacagactg cctcaaaaca
      601 ggttgatggt gattacgtcg tgtctgaatg gagtgagatt atagaattct gtacagcaga
      661 ttactccaaa gttcatctaa cacagctgct ggagaaggct gacgtgattg caggacgcat
      721 gcttaagttc tctgttttct atcggaacca gcacaaagag tattttgact atgtgagaga
      781 acactatggg aatgctatgc agccttccat caaggataac agtggtagcc atggctcacc
      841 catcagtggg aaactggaag gcatcttctt cagctgcagc actgagttca atacagggaa
      901 gccaccccag gattcaccat atggaagata caggtttgag attgcagcag aaaaactttt
      961 caaccccaat actaacttat actttgggga cttctactgt atgtacacgg cttatcatta
     1021 tgtgattctt gtcattgccc ctgtgggatc accaggagat gaattttgta agcagcgcct
     1081 tcctcaacta aattccaagg ataataattt tttgacctgt acagaagaag atggggtgct
     1141 ggtgtaccac cacgcccagg atgtcatttt agaagtcatt tacactgacc ctgtggctct
     1201 ttccctgggc accgtggcag aaatcactgg tcatcagctc atgagtttgt ctactgcaaa
     1261 tgcaaagaaa gaccccagct gcaaaacctg taacatcagt gtcggacgct aacaccactt
     1321 tcgccccttc cccgccccac acaccctgtc ttcccatagg agcattaccc tctgttgtcc
     1381 atctgccatc agatgtcccc actgaagcat gcatatgccg ctgtcaccaa aagcaaactc
     1441 tgtcattcag agcctttccg tgtctcctct tgcccgccct tgtccaccac tttcaacgat
     1501 gtccccaggt tgtcctgaca ctgtttgcct agatgctgca atgcttttat gtttccttta
     1561 tgccaaacat aacaagacag ttatatagac cgctttagca aagtacaaaa taatggctta
     1621 tcaatggtgt ttaaatgtgc atccatttta atctactgaa taaatatcgg gataactcca
     1681 aaccgcatga gagagagtaa ttgcagcatg agttaaatcc taaaagccta gacttgtcag
     1741 cacttccgcc ttgttgtttg acagtgttat ttatgttatt tatattagct aacaggaaac
     1801 agttactgtg ctttcaacat aataaatata atagaaaaat attttatttg tacgttgtat
     1861 aaaatattta caatcatata gaatatagtt acattttaat agcaattgta tacatctcac
     1921 gaaaccattt cccttatcaa agatgtaatt tgtaaacctc aaatagttgt gtatctgtcc
     1981 tgttacaagt agatgacttc gattaaacaa atttatgaag gccattactc tgattcataa
     2041 acagcaggtg aatacagaga gaacaacacg cctctgacat agtctgtgtc tagaatctgg
     2101 gttgggtttt tttttccgcc caagcaatag gaaaatctga gtttcttcaa caccatgctt
     2161 aaacatgaca gaaaacagaa ataggaacaa tgttgataat gagaaaatgt ctacctgtta
     2221 cttgatttta caaaaaccaa accagtaagt gtgtgagtgg agaaaaagca agatacacta
     2281 aataaagcaa ataaaaggtc tcttggtgat ttccaagctt ttcaccctgt gcagaatgaa
     2341 tgcagctcac aagaaagtta tttcacttta taaagtacag accttggaac attaagaaag
     2401 atgcatattc ccaatggaaa aatagttata taatcttagt ataggaaaca agaaaatcag
     2461 caatagtact atggtcacat taggttatta ctgcagacac atctatccaa aatacctatt
     2521 ttaatatttt actttaatat aaacatttgt cagtcataga caaagataat tcacaaagta
     2581 catgccatcc aagtgaactt tggtaactgg aaatgtaaat tttcaaataa cagataaaat
     2641 aatgcactac tttcatatag aaataagaga ttagcagtga cacagtcgag ttattttaga
     2701 gtgctgaacg cctacaggct tacaggacaa ggtagtggat gttgtctcgc ttaaattacc
     2761 ttccttctag ctgttttcct ccctgggtga agagcagaaa ttttctttgt ctcaccaatg
     2821 tatttaaacc atgctctttc catacatcaa taaaatcaat ttggggccac tac
//
