LOCUS       NP_666093                330 aa            linear   ROD 28-APR-2025
DEFINITION  phytanoyl-CoA hydroxylase-interacting protein [Mus musculus].
ACCESSION   NP_666093 XP_001000600 XP_900409 XP_923749
VERSION     NP_666093.1
DBSOURCE    REFSEQ: accession NM_145981.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 330)
  AUTHORS   Raspa,M., Guan,M., Paoletti,R., Montoliu,L., Ayadi,A.,
            Marschall,S., Fray,M. and Scavizzi,F.
  CONSRTM   EMMA/Infrafrontier Technical Working Group
  TITLE     Dry ice is a reliable substrate for the distribution of frozen
            mouse spermatozoa: A multi-centric study
  JOURNAL   Theriogenology 96, 49-57 (2017)
   PUBMED   28532839
REFERENCE   2  (residues 1 to 330)
  AUTHORS   Kim,M.Y., Jeong,B.C., Lee,J.H., Kee,H.J., Kook,H., Kim,N.S.,
            Kim,Y.H., Kim,J.K., Ahn,K.Y. and Kim,K.K.
  TITLE     A repressor complex, AP4 transcription factor and geminin,
            negatively regulates expression of target genes in nonneuronal
            cells
  JOURNAL   Proc Natl Acad Sci U S A 103 (35), 13074-13079 (2006)
   PUBMED   16924111
REFERENCE   3  (residues 1 to 330)
  AUTHORS   Koh,J.T., Jeong,B.C., Kim,J.H., Ahn,Y.K., Lee,H.S., Baik,Y.H. and
            Kim,K.K.
  TITLE     Changes underlying arrhythmia in the transgenic heart
            overexpressing Refsum disease gene-associated protein
  JOURNAL   Biochem Biophys Res Commun 313 (1), 156-162 (2004)
   PUBMED   14672712
REFERENCE   4  (residues 1 to 330)
  AUTHORS   Koh,J.T., Choi,H.H., Ahn,K.Y., Kim,J.U., Kim,J.H., Chun,J.Y.,
            Baik,Y.H. and Kim,K.K.
  TITLE     Cardiac Characteristics of Transgenic Mice Overexpressing Refsum
            Disease Gene-Associated Protein within the Heart
  JOURNAL   Biochem Biophys Res Commun 286 (5), 1107-1116 (2001)
   PUBMED   11527414
REFERENCE   5  (residues 1 to 330)
  AUTHORS   Koh,J.T., Lee,Z.H., Ahn,K.Y., Kim,J.K., Bae,C.S., Kim,H.H.,
            Kee,H.J. and Kim,K.K.
  TITLE     Characterization of mouse brain-specific angiogenesis inhibitor 1
            (BAI1) and phytanoyl-CoA alpha-hydroxylase-associated protein 1, a
            novel BAI1-binding protein
  JOURNAL   Brain Res Mol Brain Res 87 (2), 223-237 (2001)
   PUBMED   11245925
REFERENCE   6  (residues 1 to 330)
  AUTHORS   Lee,Z.H., Kim,H., Ahn,K.Y., Seo,K.H., Kim,J.K., Bae,C.S. and
            Kim,K.K.
  TITLE     Identification of a brain specific protein that associates with a
            refsum disease gene product, phytanoyl-CoA alpha-hydroxylase
  JOURNAL   Brain Res Mol Brain Res 75 (2), 237-247 (2000)
   PUBMED   10686344
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK049900.1.
            
            On or before Aug 17, 2006 this sequence version replaced
            XP_900409.2, XP_923749.2, XP_001000600.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK049900.1, BC030494.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 36.32 cM"
     Protein         1..330
                     /product="phytanoyl-CoA hydroxylase-interacting protein"
                     /note="lupus nephritis-associated peptide 1 interacting
                     protein; PAHXAP1; phytanoyl-CoA hydroxylase-associated
                     protein 1"
                     /calculated_mol_wt=37424
     Region          5..112
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Site            14
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000305; propagated from
                     UniProtKB/Swiss-Prot (Q8K0S0.1)"
     Site            order(96..97,104..105)
                     /site_type="active"
                     /note="Cytokine receptor motif [active]"
                     /db_xref="CDD:238020"
     Region          111..330
                     /region_name="PHYHIP_C"
                     /note="Phytanoyl-CoA hydroxylase-interacting protein
                     C-terminus; pfam19281"
                     /db_xref="CDD:437113"
     Site            325
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000305; propagated from
                     UniProtKB/Swiss-Prot (Q8K0S0.1)"
     CDS             1..330
                     /gene="Phyhip"
                     /gene_synonym="C630010D02Rik; Lnap1ip; PAHX-AP#1;
                     PAHX-AP1"
                     /coded_by="NM_145981.3:308..1300"
                     /db_xref="CCDS:CCDS36971.1"
                     /db_xref="GeneID:105653"
                     /db_xref="MGI:MGI:1860417"
ORIGIN      
        1 mellstphsi einnitcdsf riswamedsd lervthyfid lnkkenknsn kfkhrdvptk
       61 lvakavplpm tvrghwflsp rteysvavqt avkqsdgeyl vsgwsetvef ctgdyakehl
      121 aqlqekaeqi agrmlrfsvf yrnhhkeyfq harthcgnvl qpylkdnsgs hgsptsgmlh
      181 gvffscntef ntgqppqdsp ygrwrfqipa qrlfnpstnl yfadfycmyt ayhyailvla
      241 pkgslgdrfc rdrlplldia cnkfltcsve dgelifrhaq dlileiiyte pvdlslgtlg
      301 eisghqlmsl stadakkdps cktcnisvgr
//
