LOCUS       NM_028521               2104 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus phosphatase, orphan 2 (Phospho2), mRNA.
ACCESSION   NM_028521
VERSION     NM_028521.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2104)
  AUTHORS   Roberts,S.J., Stewart,A.J., Schmid,R., Blindauer,C.A., Bond,S.R.,
            Sadler,P.J. and Farquharson,C.
  TITLE     Probing the substrate specificities of human PHOSPHO1 and PHOSPHO2
  JOURNAL   Biochim Biophys Acta 1752 (1), 73-82 (2005)
   PUBMED   16054448
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK006724.1.
            
            On Apr 6, 2007 this sequence version replaced NM_028521.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK006724.1, SRR1660815.63348.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2104              AK006724.1         2-2105
FEATURES             Location/Qualifiers
     source          1..2104
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 40.95 cM"
     gene            1..2104
                     /gene="Phospho2"
                     /gene_synonym="1700048E23Rik; Phos2"
                     /note="phosphatase, orphan 2"
                     /db_xref="GeneID:73373"
                     /db_xref="MGI:MGI:1920623"
     exon            1..220
                     /gene="Phospho2"
                     /gene_synonym="1700048E23Rik; Phos2"
                     /inference="alignment:Splign:2.1.0"
     exon            221..256
                     /gene="Phospho2"
                     /gene_synonym="1700048E23Rik; Phos2"
                     /inference="alignment:Splign:2.1.0"
     exon            257..411
                     /gene="Phospho2"
                     /gene_synonym="1700048E23Rik; Phos2"
                     /inference="alignment:Splign:2.1.0"
     exon            412..2104
                     /gene="Phospho2"
                     /gene_synonym="1700048E23Rik; Phos2"
                     /inference="alignment:Splign:2.1.0"
     CDS             438..1163
                     /gene="Phospho2"
                     /gene_synonym="1700048E23Rik; Phos2"
                     /EC_number="3.1.3.74"
                     /codon_start=1
                     /product="pyridoxal phosphate phosphatase PHOSPHO2"
                     /protein_id="NP_082797.1"
                     /db_xref="CCDS:CCDS16099.1"
                     /db_xref="GeneID:73373"
                     /db_xref="MGI:MGI:1920623"
                     /translation="MKVLLVFDFDNTIIDDNSDTWIVQCAPDKKLPIELQDSYQKGLW
                     TEFMGRVFKYLRDEGVKADELKRAVTSLPFTSGMIELLSFLRMNKDRFDCIIISDSNS
                     IFIDWVLEAAAFHDVFDHVFTNPASFDSSGRLTVKNYHAHSCTRCPKNLCKNTVLGEF
                     IDKQLQKGVRYTRIVYIGDGGNDVCPVTFLKKNDVAMPREGYTLHRTLAKMSQNLEPM
                     ESSIVVWSSGVEIISHLQFLIKM"
     regulatory      1151..1156
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Phospho2"
                     /gene_synonym="1700048E23Rik; Phos2"
                     /note="hexamer: AATAAA"
     polyA_site      1174
                     /gene="Phospho2"
                     /gene_synonym="1700048E23Rik; Phos2"
                     /note="major polyA site"
     polyA_site      2000
                     /gene="Phospho2"
                     /gene_synonym="1700048E23Rik; Phos2"
     polyA_site      2017
                     /gene="Phospho2"
                     /gene_synonym="1700048E23Rik; Phos2"
ORIGIN      
        1 gctgatgctg gcggcccgct gcgacccagg cctgggtcag tgaggagccc tcggtcccgc
       61 tcggccgctg ccgcttttct cactcgctgc gctagtttgg aaccggccgg tgtgcgagtc
      121 gaggcccagg ctgggtgcga gcttctactc tgcgccccgc tggctgaggt gaaggacagc
      181 cctttgacca ccgagccaca aggattaaag gacagaaaag gttttctatc agagatgttc
      241 cactgtaata atgctggagt taaaaagtct ttgttccttt gctgcatatc agagcaattt
      301 ctctgcatac agaactggag taatgtttac aaacagctgg caaattgaag actgcagtgg
      361 cctaacctct gtgctgaagt agcattaatt ggactgcaag taccagtttg gggtaaccca
      421 agtctgttcc tggaaccatg aaagttctgt tggtgtttga ctttgacaat acaatcatag
      481 acgacaacag tgacacctgg attgtacagt gtgctccaga caaaaagctt cccattgagc
      541 tacaagattc ttatcaaaag gggctttgga cagaatttat gggcagagtc tttaaatatt
      601 tgagagatga gggggtaaaa gcagatgaac tgaagagggc agtgacttca ctgcccttca
      661 cctcagggat gatagaactt ctcagcttcc tgaggatgaa taaggacaga tttgactgca
      721 tcatcatttc ggattcaaat tccatcttca tagactgggt tctagaagct gctgcctttc
      781 acgatgtctt tgatcacgtg tttaccaatc cagcatcctt tgatagcagt ggtcgtctca
      841 cagtgaaaaa ttaccatgct cattcttgca ctaggtgccc aaagaatctt tgcaaaaata
      901 cagttttggg agaatttata gataaacagt tacaaaaggg cgtgagatat acacggattg
      961 tttatatagg tgatggtgga aatgatgtct gcccagtaac ttttttaaag aaaaatgatg
     1021 ttgccatgcc acgggaagga tatactttac atagaactct tgccaaaatg tctcaaaatc
     1081 ttgagcctat ggaatcttct attgtagttt ggtcttcagg tgttgaaata atttctcatt
     1141 tacaatttct aataaagatg tgatatgcca acaattgaaa ggtgtattag ttgaggttgg
     1201 gctcggcaac ataaaactaa attcccaata ttagaacctt taaaaatgtg agaggttttc
     1261 ctctttaaag aattctggtg gtatgtcaag gccacttcgt tgctcagcca atctcagctt
     1321 ctgcttctaa ccccgtgatt tgaaattgat atctaaagct caagtcctca caacagacat
     1381 tgtgaccagc aagaatcagg gccataggat ttttaccctt tgttcaggaa tgttttccaa
     1441 ttgtaccaaa cagttctgtt tgaataccac tagccaaaac ctggtcagag ccttccctaa
     1501 ctgcacagat gggaaatgca gctttcattc caggtagtcc tgtgcccagg aaaaagagga
     1561 aaaacaaaat acataattga ggtatgtgga gctcatagtc tatactaagg atggttaata
     1621 gattgttttg tttttatttc tgaagaaagt ggctttattt tactttttat gaaatagtta
     1681 caaatgttga aagtagctca tgagctctct tcccctgatg tcaagtcatg aagagaccca
     1741 agtgtgttca agattcagct tcacccacaa cccgctagga ctgaggaagg cattattgct
     1801 ggaggtgtaa tggatcttac tgcctaacag gagcactgaa gactgccttc atccaagagg
     1861 gcccagcatg gggatatacg ccttggatca tcgctgccaa agccttaggc aagtgcatgc
     1921 ttgaacccta ttgtgatgag cgtcaagttg gtggagaagc tttgtgctga gcctgaagat
     1981 caaactaatc aggcatctgt gaaaaaaaga gagaaaaccc tagagacttg gttgtggtgt
     2041 gttaaggatg ccaactgaag actacttcaa atgcaagaaa taaaactggc tttattttct
     2101 caac
//
