LOCUS       NM_001413419            5734 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus pleckstrin homology like domain, family B, member 1
            (Phldb1), transcript variant 1, mRNA.
ACCESSION   NM_001413419
VERSION     NM_001413419.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5734)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5734)
  AUTHORS   Zhou,Q.L., Jiang,Z.Y., Mabardy,A.S., Del Campo,C.M.,
            Lambright,D.G., Holik,J., Fogarty,K.E., Straubhaar,J., Nicoloro,S.,
            Chawla,A. and Czech,M.P.
  TITLE     A novel pleckstrin homology domain-containing protein enhances
            insulin-stimulated Akt phosphorylation and GLUT4 translocation in
            adipocytes
  JOURNAL   J Biol Chem 285 (36), 27581-27589 (2010)
   PUBMED   20587420
  REMARK    GeneRIF: PHLDB1 is a novel modulator of Akt protein kinase
            activation by insulin.
REFERENCE   3  (bases 1 to 5734)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5734)
  AUTHORS   Kerns,R.T., Ravindranathan,A., Hassan,S., Cage,M.P., York,T.,
            Sikela,J.M., Williams,R.W. and Miles,M.F.
  TITLE     Ethanol-responsive brain region expression networks: implications
            for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J
            mice
  JOURNAL   J Neurosci 25 (9), 2255-2266 (2005)
   PUBMED   15745951
REFERENCE   5  (bases 1 to 5734)
  AUTHORS   Katoh,M. and Katoh,M.
  TITLE     Identification and characterization of human LL5A gene and mouse
            Ll5a gene in silico
  JOURNAL   Int J Oncol 23 (5), 1477-1483 (2003)
   PUBMED   14532993
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC142113.2 and AC151971.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219380.22414.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-74                AC142113.2         110308-110381       c
            75-155              AC142113.2         103203-103283       c
            156-279             AC142113.2         102234-102357       c
            280-450             AC142113.2         101193-101363       c
            451-576             AC151971.3         4377-4502
            577-1928            AC151971.3         6111-7462
            1929-2210           AC151971.3         10854-11135
            2211-2351           AC151971.3         11488-11628
            2352-2489           AC151971.3         11716-11853
            2490-2618           AC151971.3         14254-14382
            2619-2774           AC151971.3         14736-14891
            2775-2885           AC151971.3         18605-18715
            2886-2975           AC151971.3         18884-18973
            2976-3119           AC151971.3         19540-19683
            3120-3260           AC151971.3         21690-21830
            3261-3401           AC151971.3         23080-23220
            3402-3504           AC151971.3         23327-23429
            3505-3799           AC151971.3         24556-24850
            3800-3890           AC151971.3         24934-25024
            3891-4037           AC151971.3         26593-26739
            4038-4154           AC151971.3         28286-28402
            4155-4257           AC151971.3         28645-28747
            4258-4343           AC151971.3         34074-34159
            4344-5734           AC151971.3         35078-36468
FEATURES             Location/Qualifiers
     source          1..5734
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 24.84 cM"
     gene            1..5734
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /note="pleckstrin homology like domain, family B, member
                     1"
                     /db_xref="GeneID:102693"
                     /db_xref="MGI:MGI:2143230"
     exon            1..74
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            75..155
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            156..279
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            280..450
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            451..576
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            577..1928
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            1929..2210
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2211..2351
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2352..2489
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2490..2618
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2619..2774
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2775..2885
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2886..2975
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2976..3119
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            3120..3260
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            3261..3401
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            3402..3504
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            3505..3799
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            3800..3890
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            3891..4037
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            4038..4154
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            4155..4257
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            4258..4343
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            4344..5734
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5712..5717
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /note="hexamer: AATAAA"
     polyA_site      5734
                     /gene="Phldb1"
                     /gene_synonym="D330037A14Rik; Ll5a; Ll5alpha"
                     /note="major polyA site"
ORIGIN      
        1 agagtcttcg ccagcctgag gccgccgcgg cccacttggg caaaggggcc ggtgtccccc
       61 caactcccca caaggagttc tggcgccctt ggatcatgga tcctctcaat aggagccagc
      121 taggccctgg atgcaagacc caggctgtag tgcagaaagg gccattggat ctgattgaga
      181 cgggtcaagg actgaaggtg cagacggaca aacctcatct ggtgagcctg ggcagcggga
      241 gactcagcac agcgatcact ctcctgccgc tggaggaagg gaggacagtc attggttctg
      301 cagccaggga catctcactg cagggtccag gcctggctcc agaacactgc tacatcgaga
      361 atctgcgggg cactctcacc ctgtaccctt gtggcaatgc ctgcactatt gatgggctcc
      421 ctgttcggca gcccacccgg ctcactcagg gctgcatgtt gtgtctgggt caatccacct
      481 tcctgcgctt taaccatcca gccgaagcca agtggatgaa aagtatgatt ccagcagggg
      541 tccgggcccc agggcccacc tacaaccctg gctctgctga atcggagagc ctggtcaatg
      601 ggaaccacac agcacaacct gcaacccggg caccgtcagc ctgtgccagc cacagttccc
      661 tggtgagctc tattgaaaag gacctgcagg aaatcatgga ttcattggtg ctagaggagc
      721 ctggagctgc aggcaagaag cctgctgcca catccccatt gtcgccaatg gctaacggcg
      781 ggcgctacct gttgtcccct ccaaccagcc ccggtgccat gtctgtgggc tccagctatg
      841 agaacacctc tccagccttc tctccacttt cctcaccagc cagcagcgga agctgtgcta
      901 gccattcacc aagtgggcag gagccaggac cctctgtgcc cccattggtg cctgcccgct
      961 cctctagcta ccatttggct ctgcaacctc cacagtctcg cccaagtggt tcccgctcct
     1021 ctgacagtcc ccggctgggc agaaaagggg gtcatgagag acctcccagc cctggtctcc
     1081 ggggtcttct gacggacagt cctgccgcta ccgtcttggc tgaggcccgc agaaccactg
     1141 agagtccccg gctaggtggg cagttacctg tggtggctat cagcctgagt gaatacccat
     1201 cttccggtgc ccgcagccaa cccgccagta ttcctggcag ccccaagttc cagtctccag
     1261 tgcctgctcc ccgaaacaag atcggcacac tccaggaccg ccctcccagt cctttccgtg
     1321 agcccccagg cacagagcgg gtactaacaa gcagcccctc tcgacaactg gtgggcagaa
     1381 cattttcgga tgggttagca gcaactcgta ccctccagcc gcctgagagt ccccgcctgg
     1441 gccggagggg cctggacagt atgcgggaac tgcccccgtt gagtccatct ctgtctcgaa
     1501 gggctctgtc cccactgcca gcccggactg ccccagatcc caagctaagc agggaagtgg
     1561 ccgagagtcc ccggccccgg cgctgggcag cccacgggac ttcacctgag gacttctccc
     1621 tgactctagg agcacggggt cgcaggactc ggagtccctc gcccaccctc ggggagtccc
     1681 tggcacctcg caagggtagc ttcagtggca ggctgagccc agcttacagt ctgggctctc
     1741 ttactggggc ttcacctcgt cagagccccc gtgctcagcg gaagctctcc agtggggact
     1801 tgcgggtacc cattccaagg gagaggaaaa acagcatcac ggagatcagc gacaatgagg
     1861 acgaacttct ggagtaccac cgtcggcagc gccaagagcg gctccgggag caggagatgg
     1921 agaggctgga acgccagcgc ctggagacca tcctgaacct gtgtgctgag tacagccgag
     1981 ctgacggggg acctgagact ggggagctgc ccagtattgg agaggccacg gcagcgctgg
     2041 ccttggcagg caggaggccc tcaagaggct tggcaggagc catagtagtc tccggaaggt
     2101 gcggcgagga gtctggaggt gcctcccagc gcctgtggga gagcatggag cgctctgatg
     2161 aagagaatct caaagaggaa tgcagcagca ccgagagcac ccagcaggag catgaagacg
     2221 ctcctggcgc gaagcaccaa ggcgaggtgc tggctgtgga agaggagcgg gctcaggttc
     2281 tggggcgagt agaacagctg aagatccgag tgaaggagct ggaacagcag ctgcaggagg
     2341 cagcccgaga ggccgagatg gagagagcac tgctgcaggg ggagcgggag gcagagcgag
     2401 cctcgctgca gaaggaacaa agggcggtgg accagctgca ggagaagttg gtggccttgg
     2461 agacaggcat ccagaaggac agggacaagg agagggcgga gctggccgcg ggacggaggc
     2521 acctggaggc ccgccaggcg ctctacgccg agctccagac gcagctcgat aactgccccg
     2581 agtcagtgcg ggaacagtta caggagcagc tgagaaggga ggcagacgct ctagagactg
     2641 agacaaagct ctttgaggac ctggagttcc agcagctgga gcgtgagagt cgcgtggagg
     2701 aggagcggga gctggccggc caagggctgc tgcggagcaa ggctgagttg ctgcgcagtg
     2761 tgagcaagag gaaggagcgc ctagctgtac tggacagtca ggctgggcag atccgggccc
     2821 aggcagtaca ggagtcagag cgtctggccc gggaaaagaa tgctgccctg cagctactgc
     2881 aaaaggagaa ggagaagctg aatgtccttg agaggagata ccattcgctc acggggggca
     2941 ggccttttcc gaagaccacc tccaccctca aagaggctca gctactcatc tccgaggcct
     3001 cagagatagg gctggagacc aaagctctgg gccagtcccc aaggtcttct gaggctgggg
     3061 cctcctctgt tctcttaacc cctcctgctt ccactcagct ctgtcccaaa gcacaagaga
     3121 tggagaagct gctgctccct gctgtagact tagagcagtg gtaccaggag ttgatgtccg
     3181 ggctggggac tggccttgct gcagcctccc ctcgctcctc tcccccgcct ttgcctgcca
     3241 aagcttcccg tcagctgcag gtttaccgct ccaagatgga tagtgatgcg gccagccccc
     3301 tgcccaggac ccgtagcggc cctctcccct cctcctcagg ctcctcctcc tcctcttcac
     3361 agctcagcgt ggctaccctg ggccgtagtc cttccccaaa gagtgctctg ctcgcccaga
     3421 atggcaccag tagccttcct cgcaacctgg cagccacact gcaggacatt gagaccaagc
     3481 gccagctggc cctacagcaa aagggacacc aagtgatcga ggagcaacgg aggagactgg
     3541 cggagctgaa gcagaaggcg gcggcagagg ctcagtgcca gtgggatgcc ttgcatggtg
     3601 cagggccctt ttcagcaggc ccttcaggct tccctgcact catgcatcat tccatcctgc
     3661 atcacctgcc agctggccgg gagcgtggag aggagggcga gcacgcttac gacaccctga
     3721 gcctggagag ttcagacagc atggagacca gcatctctac aggcggcaac tctgcctgtt
     3781 ccccggacaa catgtccagc gccagtggtc tggacatggg caagatcgag gaaatggaga
     3841 agatgctaaa ggaagctcac gcagagaaga gccggctcat ggagtccagg gagcgggaga
     3901 tggagcttcg gaggcaggcc ctggaggagg aacggaggag gcgggagcaa gtggagcggc
     3961 ggctgcagag tgagagcgcc cgcaggcagc agctggtgga gaaagaagtc aagctccggg
     4021 aaaagcagtt ctcccaggca cggcctctta cacgttacct tcccaaccgg aaggaggact
     4081 ttgatctgaa gacccacata gagtcatcag gccacggggt ggacacctgc ctacatgtgg
     4141 tgcttagcag caaggtgtgc cgtggctacc tgatcaagat gggtggcaag attaaatcgt
     4201 ggaagaagcg ctggtttgtc tttgatcggc tgaagcgcac cctttcctat tacgtggaca
     4261 aacatgagac gaagctgaag ggggtcatct atttccaggc catcgaggaa gtgtactatg
     4321 accacctgcg cagcgcagcc aagagtccga atccggccct caccttctgt gtgaagaccc
     4381 atgaccggtt gtactacatg gtggccccgt ctgcagaggc catgcgcatc tggatggatg
     4441 tcatcgtcac gggggccgag ggctacactc aattcatgaa ctaactaccc tgcacctcct
     4501 gggttcccca gctcagcccc aggactccgt gccctgccac ctgccactct gcttgtccct
     4561 ggggacagtg gcacattggg cacggggctg caaaggatcg ggatgtagtt gagtacctcg
     4621 gggcttttgt gcaagaagac aaattgtgtt atgaggagtt tggtgcttgg gaattgagct
     4681 ccagtcccta aagagccagc agagaggaaa ggaagaggga gaggccttgt cggtcctggg
     4741 agtccagaag ttcaggttcc ctcctgggtc cagcaggctg aagaggctgc tgagctgcgc
     4801 tctcggctct gtcccggcac ccacccaccc cagcttgttt tctctttgta aaggacaaac
     4861 tatggtacca gaatctgcca aagatcccct tctcatctca tcccctctgc aggggctggg
     4921 aggggtcctg agcagagcca cgtgcagagc tggggagcgg ctcaggcccc aaccccatct
     4981 gcctcctcct cttcttcctc ttcctcctcc tcccacctcc cacttgtcac tactcagctc
     5041 aaggaccaga gacctcaagt gtcactttcg aggtccagcc ccatcatcct gttacaagcc
     5101 cgtcatcctt gtctccatgg tgaccgcttc atcaccatgg ttacacacta attgccatgg
     5161 ccactctgtg gctttgccca ctgcttctgg ctgtgggcca catgagggta cgtgccatca
     5221 tctctccaac ccaggcctgg gggcatgtca catggtggga ggagatggaa ttcctcccgg
     5281 ctgcagtgtg tctccagccc ccagcccagc ccctctccct tttactgtgc cttgcttaga
     5341 gccagaaggg atgatgtcct gggatccaag accagaggga cagcatcact gaggggagag
     5401 gaagctgaga ggtctgccct cccattctaa caggactagt tcccagtgag gaacaagggt
     5461 agctcagagt gcctgcaaag aagcctgagt tggggctggg gcgggcagaa gcagaggccc
     5521 tgagctgtgg taatctccct tcagtttccc aaaggtgatg ggaaaggaga acggaggata
     5581 agtctccagc tggctggcct cagccttgcg ccttaacact aagccacctt ccctgccctc
     5641 cccagcactg ggcccttagt tgctgggcct ggttgggtgt tttgcagtat ttgtaagcat
     5701 ttcagcagaa caataaaagc attttgacta tgta
//
