LOCUS       NM_026737               1648 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus PHD finger protein 5A (Phf5a), mRNA.
ACCESSION   NM_026737
VERSION     NM_026737.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1648)
  AUTHORS   Zhang,R., Wang,D., Ruan,G.X., Wang,R., Li,Y., Chen,W., Huang,H.,
            Wang,J., Meng,L., Zhu,Z., Lei,D., Xu,S. and Ou,X.
  TITLE     Spliceosome component PHD finger 5A is essential for early B
            lymphopoiesis
  JOURNAL   Development 151 (2) (2024)
   PUBMED   38095286
REFERENCE   2  (bases 1 to 1648)
  AUTHORS   Strikoudis,A., Lazaris,C., Trimarchi,T., Galvao Neto,A.L., Yang,Y.,
            Ntziachristos,P., Rothbart,S., Buckley,S., Dolgalev,I.,
            Stadtfeld,M., Strahl,B.D., Dynlacht,B.D., Tsirigos,A. and
            Aifantis,I.
  TITLE     Regulation of transcriptional elongation in pluripotency and cell
            differentiation by the PHD-finger protein Phf5a
  JOURNAL   Nat Cell Biol 18 (11), 1127-1138 (2016)
   PUBMED   27749823
  REMARK    GeneRIF: Phf5a controls differentiation of adult myoblasts
REFERENCE   3  (bases 1 to 1648)
  AUTHORS   Shimizu,H., Kubo,A., Uchibe,K., Hashimoto,M., Yokoyama,S.,
            Takada,S., Mitsuoka,K. and Asahara,H.
  TITLE     The AERO system: a 3D-like approach for recording gene expression
            patterns in the whole mouse embryo
  JOURNAL   PLoS One 8 (10), e75754 (2013)
   PUBMED   24146773
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1648)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 1648)
  AUTHORS   Rzymski,T., Grzmil,P., Meinhardt,A., Wolf,S. and Burfeind,P.
  TITLE     PHF5A represents a bridge protein between splicing proteins and
            ATP-dependent helicases and is differentially expressed during
            mouse spermatogenesis
  JOURNAL   Cytogenet Genome Res 121 (3-4), 232-244 (2008)
   PUBMED   18758164
  REMARK    GeneRIF: results indicate that PHF5A resembles a protein which
            interacts with splicing factors U2AF1 and SFRS5 and helicases EP400
            and DDX1 and functions as a bridge protein between these proteins
REFERENCE   6  (bases 1 to 1648)
  AUTHORS   Trappe,R., Ahmed,M., Glaser,B., Vogel,C., Tascou,S., Burfeind,P.
            and Engel,W.
  TITLE     Identification and characterization of a novel murine multigene
            family containing a PHD-finger-like motif
  JOURNAL   Biochem Biophys Res Commun 293 (2), 816-826 (2002)
   PUBMED   12054543
  REMARK    GeneRIF: molecular cloning and characterization of Phf5a
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK143590.1.
            
            On Apr 5, 2007 this sequence version replaced NM_026737.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143590.1, BC025161.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1648              AK143590.1         2-1649
FEATURES             Location/Qualifiers
     source          1..1648
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 38.26 cM"
     gene            1..1648
                     /gene="Phf5a"
                     /gene_synonym="1110007B08Rik"
                     /note="PHD finger protein 5A"
                     /db_xref="GeneID:68479"
                     /db_xref="MGI:MGI:2156864"
     exon            1..80
                     /gene="Phf5a"
                     /gene_synonym="1110007B08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..361
                     /gene="Phf5a"
                     /gene_synonym="1110007B08Rik"
                     /note="SF3b14b; PHD finger-like domain protein 5A;
                     splicing factor 3B-associated 14 kDa protein"
                     /codon_start=1
                     /product="PHD finger-like domain-containing protein 5A"
                     /protein_id="NP_081013.1"
                     /db_xref="CCDS:CCDS27674.1"
                     /db_xref="GeneID:68479"
                     /db_xref="MGI:MGI:2156864"
                     /translation="MAKHHPDLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVR
                     ICDECNYGSYQGRCVICGGPGVSDAYYCKECTIQEKDRDGCPKIVNLGSSKTDLFYER
                     KKYGFKKR"
     exon            81..104
                     /gene="Phf5a"
                     /gene_synonym="1110007B08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            105..271
                     /gene="Phf5a"
                     /gene_synonym="1110007B08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            272..1648
                     /gene="Phf5a"
                     /gene_synonym="1110007B08Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      821..826
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Phf5a"
                     /gene_synonym="1110007B08Rik"
                     /note="hexamer: AATAAA"
     polyA_site      847
                     /gene="Phf5a"
                     /gene_synonym="1110007B08Rik"
                     /note="major polyA site"
ORIGIN      
        1 ttccggccgc cggcttggaa aaagagttat ggctaaacat catccagatt tgattttctg
       61 ccgcaagcag gctggtgtgg ctatcggaag actgtgtgaa aaatgtgacg gcaagtgtgt
      121 gatctgtgat tcctacgtgc gtccctgcac cctggtccgc atatgtgatg agtgtaacta
      181 tggatcttac cagggccggt gtgtaatctg tggcggcccc ggagtctccg atgcctacta
      241 ctgtaaagag tgcaccattc aggagaagga tagagatggt tgtccaaaga ttgtcaattt
      301 ggggagctct aagacagacc tgttctatga acgcaaaaaa tacggcttca agaagaggtg
      361 atgggtgggt ggctccttcc tcccccatca aactgctgca gctgccagaa tagacgccta
      421 ctaccaccgc ctaaagggaa cggagctgag tgtcaccaga gcagcctgct agtgctagtg
      481 tcctggcccc tgccactagc aagtgcccat ggagcatctg gcagactgga ggagacgttg
      541 ctcgcttagt ccctagttcc ctttttgttt tgagttggaa aagcaaggct ctgttctcca
      601 cattgatcct ttcaactcaa aagcctcaaa acaagttggt gtgtgtcctt ggtgatgaaa
      661 ctgtcccggc agaagtgtgg tcttgcagca gctatgatgg ggttgtcctg tgaccctcag
      721 tgtggccagg tgtgacctga acagtaatgt gacctgacaa tttgcaggtg gtgctgggct
      781 cgtgttattt tccttgtaag ttggaagttt caattacgct aataaagttg gctaccttcc
      841 ccgttaactt tgaacgtcta cttttagtca tctaggtttt ggtgactaga accaacctag
      901 aggctgtggg gctaatgatg gacgggcaga ctggaggaga cgttgctcgc tttgccctct
      961 catggaaaga actcagagga ccctgagggt gaatgaggcc attttagttt tagggtgttt
     1021 ttttttttcc atatccaaat ttttattttt gtctcactca atagctcagg ctggcctgaa
     1081 aactattggt gatcctcctg ccttagcctt tagagtcttg acatttcata tgtaaatgac
     1141 cagacctgag ttttctaata ccgatttcaa agagatgtcc tacagtaatg gtgaggaaaa
     1201 taagataaaa ttaggttgat taattagagg aactttggtt tgtttcctgc agtgtatata
     1261 atttatttga agggtatgtt tcctttttta aaaaatgtaa gattttgtgt atgaatgttt
     1321 tgtttgcatg tatgtatgtg tgcatgcttg gtacctagag ttaagggcag cagacacccc
     1381 tggagttctg ggtggatatg aactaccatg tgagtgctgg gaatcaaacc tagggccttt
     1441 tcaagagcaa cggtcatctc accagcccca acaaatatct tgtaaattac ccaaattaga
     1501 aaattcagcc atatccatct atgtgggtca gttcattgct gcctactgat gggagagttg
     1561 tcagggaggg cgttggcctt gtttgtactc caacctagta acaaagtcat ggcaagaaat
     1621 aaacttttaa gggttttggt ttgagtcc
//
