LOCUS       NM_172705               3128 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus PHD finger protein 13 (Phf13), mRNA.
ACCESSION   NM_172705
VERSION     NM_172705.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3128)
  AUTHORS   Frohns,A., Frohns,F., Naumann,S.C., Layer,P.G. and Lobrich,M.
  TITLE     Inefficient double-strand break repair in murine rod photoreceptors
            with inverted heterochromatin organization
  JOURNAL   Curr Biol 24 (10), 1080-1090 (2014)
   PUBMED   24794298
  REMARK    GeneRIF: Rods fail to robustly accumulate active ATM at DNA
            double-strand breakd, exhibit low KAP1 levels, and display high
            levels of SPOC1, a factor suppressing KAP1 phosphorylation. This
            results in dramatically reduced KAP1 phosphorylation.
REFERENCE   2  (bases 1 to 3128)
  AUTHORS   Bordlein,A., Scherthan,H., Nelkenbrecher,C., Molter,T., Bosl,M.R.,
            Dippold,C., Birke,K., Kinkley,S., Staege,H., Will,H. and
            Winterpacht,A.
  TITLE     SPOC1 (PHF13) is required for spermatogonial stem cell
            differentiation and sustained spermatogenesis
  JOURNAL   J Cell Sci 124 (Pt 18), 3137-3148 (2011)
   PUBMED   21852425
  REMARK    GeneRIF: indispensable for stem cell differentiation in the testis
            and for sustained spermatogenesis
REFERENCE   3  (bases 1 to 3128)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 3128)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 3128)
  AUTHORS   Mohrmann,G., Hengstler,J.G., Hofmann,T.G., Endele,S.U., Lee,B.,
            Stelzer,C., Zabel,B., Brieger,J., Hasenclever,D., Tanner,B.,
            Sagemueller,J., Sehouli,J., Will,H. and Winterpacht,A.
  TITLE     SPOC1, a novel PHD-finger protein: association with residual
            disease and survival in ovarian cancer
  JOURNAL   Int J Cancer 116 (4), 547-554 (2005)
   PUBMED   15825179
REFERENCE   6  (bases 1 to 3128)
  AUTHORS   Okada,A., Kushima,K., Aoki,Y., Bialer,M. and Fujiwara,M.
  TITLE     Identification of early-responsive genes correlated to valproic
            acid-induced neural tube defects in mice
  JOURNAL   Birth Defects Res A Clin Mol Teratol 73 (4), 229-238 (2005)
   PUBMED   15799026
REFERENCE   7  (bases 1 to 3128)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC059282.1 and BC020286.1.
            
            On Jan 10, 2008 this sequence version replaced NM_172705.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY069976.2, AK132066.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2406              BC059282.1         1-2406
            2407-3128           BC020286.1         1456-2177
FEATURES             Location/Qualifiers
     source          1..3128
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 82.81 cM"
     gene            1..3128
                     /gene="Phf13"
                     /gene_synonym="Phf5; SPOC1"
                     /note="PHD finger protein 13"
                     /db_xref="GeneID:230936"
                     /db_xref="MGI:MGI:2446217"
     exon            1..354
                     /gene="Phf13"
                     /gene_synonym="Phf5; SPOC1"
                     /inference="alignment:Splign:2.1.0"
     CDS             316..1206
                     /gene="Phf13"
                     /gene_synonym="Phf5; SPOC1"
                     /note="PHD zinc finger protein PHF5"
                     /codon_start=1
                     /product="PHD finger protein 13"
                     /protein_id="NP_766293.2"
                     /db_xref="CCDS:CCDS51388.1"
                     /db_xref="GeneID:230936"
                     /db_xref="MGI:MGI:2446217"
                     /translation="MDSDSCAAAFHPEEYSPTCKRRRTVEDFNKFCTFVLAYAGYIPY
                     PKEELPLRSSPSPANSTAGTIDSDGWDTGFSDITPSVPDRCFSHLQPSLLQRAKPSNY
                     LLDRKTTDKLKKKKRRKRRDSDIPVKEGFRESLLKLEAADPYVETPSSPTMQDIPQAS
                     ADPCSGWDSDTPSSGSCATVSPDQVTEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIM
                     VDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDS
                     KFDIRRSNRSRMGSRKLFLD"
     exon            355..456
                     /gene="Phf13"
                     /gene_synonym="Phf5; SPOC1"
                     /inference="alignment:Splign:2.1.0"
     exon            457..979
                     /gene="Phf13"
                     /gene_synonym="Phf5; SPOC1"
                     /inference="alignment:Splign:2.1.0"
     exon            980..3128
                     /gene="Phf13"
                     /gene_synonym="Phf5; SPOC1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3107..3112
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Phf13"
                     /gene_synonym="Phf5; SPOC1"
                     /note="hexamer: AATAAA"
     polyA_site      3128
                     /gene="Phf13"
                     /gene_synonym="Phf5; SPOC1"
                     /note="major polyA site"
ORIGIN      
        1 cggggagccg gtcgggttcc cgctcgctgt ctccgccgcc gccccccaca gtgcctctcc
       61 cgcctctcca cagcgcgggt cgtgggagct gcatcctcca ctcagttcgc tgtggacact
      121 ccagttcggg atcagcgagc ctgcgacgcg acatcccgac acccccgtca cctccagccc
      181 gggcgacccc tccccggccg ggtccgccct cgccctgtgc ggtgccggag ccccctggcc
      241 ctgagcgtcc cgtgggcccg ctcccgcact ccggcctcgg cactcccaca gccgccgccg
      301 ccccccaccc ggaacatgga ctccgactcc tgcgccgccg ccttccaccc cgaggagtac
      361 tcccccactt gtaagaggcg ccggactgtg gaagacttca acaaattctg caccttcgtc
      421 ttggcatatg cgggctacat cccctaccca aaggaggagc tccccctgag gagcagtccc
      481 agccccgcca acagcactgc cgggaccatt gacagcgacg gctgggacac tggtttctct
      541 gacatcacgc cttcagtgcc cgaccgatgc ttcagccacc tgcagccttc cctcttgcag
      601 agagctaagc ccagtaacta ccttctggac aggaagacaa ctgacaagct gaagaagaag
      661 aagaggagga agcgcaggga cagcgacata cctgtgaagg agggattcag ggagagcctg
      721 ctgaagctgg aagctgcaga cccatatgtg gagactccct caagccccac catgcaggat
      781 attccccagg cgtctgctga cccctgctca ggctgggact ctgacacacc ctcaagtggc
      841 tcttgtgcta ctgtgtcacc tgatcaggtc acagaaataa aaactgaagg aaaacggact
      901 attgtccgcc agggaaagca ggtggtgttc cgagacgaag acagcactgg caatgatgaa
      961 gacatcatgg tggactcaga tgatgattcc tgggacctcg tcacctgttt ctgcatgaag
     1021 ccctttgccg gccgccccat gatcgagtgt aacgagtgcc acacctggat tcacctgtcc
     1081 tgtgcaaaga tccgcaagtc caatgtcccg gaagtttttg tctgccaaaa gtgccgggac
     1141 tccaagtttg atatccgtcg ctccaaccgg tcccgaatgg gctcccggaa gctgtttctg
     1201 gactgatctg gagctgtgga ggagataggc gggactggaa gggcctgggc tctagcctcc
     1261 cttagttgag cacagaactc acagctctgg tgcaggcaga ccctgccact caggtgccta
     1321 agcaaaggac aagccgtcca gatagaactg tacatagcta gtgagcagat caaaccgtga
     1381 gagctgctgc tccagctatg ttctctgcat tggaggcaga cagagcacca ggtctgcttc
     1441 agctaacagt gagggcacac agtcattgtt agccagtcgc cgccattggg agccggtgct
     1501 agctgtcctg tctccgctgt gctcgggagt ggaggtgttg tgtttccctg gctgtttgtt
     1561 ctcagtgttg ctcttttatc acaagtgtct atacagcagc cgtccaagtt gcccgccctt
     1621 ttgtggtctc acttccttgc ctcagttgta cttgctgagc tgctgagctg tggtctggtg
     1681 tccccaagag gagccctggg tgggggggca gtggttcttt gggttttcac ggttggttta
     1741 aagggacaat gtgtagccgc ctttccacag agtgagggtt ggggtggagg tgttctgtgt
     1801 tcataactca gtttcttgtt ttgcacgatg taaaaaacaa aaagcatatt tttttcccca
     1861 caatacagcc caaagtattt gccactgtta cactgggtgt cccagctctg ctggtggtgc
     1921 ccagtccagt aacagtccac agaagacact gtccttgggc cctgtgtgct gttcttcaga
     1981 taatgggtga aaagaatggg cattctgcct tccatacagg ttcctggggc aaggcaaggt
     2041 ctgagtgcta gagcaccagc ttgcagagtt tcagaggtgt gaaccagagc cctggtctga
     2101 gtgagggctg gctcagctcc tggacactgg tggtcctggg gcagagggaa aggaggaaga
     2161 gggcgttggc tctcaaacca gcatctccag tgctcattct ttctccgtag tgtttcctac
     2221 ccagttgtca cgcgtattct ttgttagcct gagacagagc agagtggcca gtgtgtcacc
     2281 tttcttcccc ttcctggagt acctttgtaa ggtcacaggc attctcccac attgtcttaa
     2341 gcaccaaagg agctcagagt gtagactgta acttggcaaa tcagagcctt tttttaaaaa
     2401 aaaaaataat agcatctttc tcactcaccc agtttaactt tctttctttt tttaaatcct
     2461 gttgctcata ttaaagtaga agtactgctg agctctgtag attgtgcaga cctcaagggg
     2521 agagctcttc taaagagaag ctgtgataga aacagtcttg cccccaggct attgtgtggc
     2581 tctgatggga caaataccca ggacaagtta gaggaatttg ccaaagacct gccccatgac
     2641 agttgttgtc cagtgtcttc accctgagaa taaccaaagt tgcagtagtt tttttttctt
     2701 tttaagtgca tttaagaata tgtgtggttt tgttgtggaa cagtggagct ggccattatt
     2761 acatgtgctc agagatcaat gcctctggaa tacatttgac atctgtttgt gtttgcttgc
     2821 tttgttttta aggggatctt tccctgtggg tggtgtcaga atttggacac cttggtttgg
     2881 gggtaggttg agctgggcag ctgcaatcag cttgtttatg caaactgggc gtgagcctct
     2941 ctgggctcct ggttgatggc taatgctggg agggaagggt cagccccaag tagacccttc
     3001 ccgtgggctt tggccaggcc agacacaaca tcgtttacat gttctgtgta attataaagt
     3061 ttatgtgtat aaagcaagct gtttctgtga aactgtatat tttgtaaata aagatattgc
     3121 tactttga
//
