LOCUS       NM_019996               1893 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus phosphorylated adaptor for RNA export (Phax),
            transcript variant 1, mRNA.
ACCESSION   NM_019996
VERSION     NM_019996.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1893)
  AUTHORS   Segref,A., Mattaj,I.W. and Ohno,M.
  TITLE     The evolutionarily conserved region of the U snRNA export mediator
            PHAX is a novel RNA-binding domain that is essential for U snRNA
            export
  JOURNAL   RNA 7 (3), 351-360 (2001)
   PUBMED   11333016
REFERENCE   2  (bases 1 to 1893)
  AUTHORS   Ohno,M., Segref,A., Bachi,A., Wilm,M. and Mattaj,I.W.
  TITLE     PHAX, a mediator of U snRNA nuclear export whose activity is
            regulated by phosphorylation
  JOURNAL   Cell 101 (2), 187-198 (2000)
   PUBMED   10786834
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ157832.1, BC049590.1 and AK012949.1.
            
            On Jul 9, 2009 this sequence version replaced NM_019996.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK012949.1, BC061110.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-154               CJ157832.1         1-154
            155-1372            BC049590.1         1-1218
            1373-1893           AK012949.1         1242-1762
FEATURES             Location/Qualifiers
     source          1..1893
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 30.63 cM"
     gene            1..1893
                     /gene="Phax"
                     /gene_synonym="2810055C14Rik; 4933427L19Rik; D18Ertd65e;
                     p55; Rnuxa"
                     /note="phosphorylated adaptor for RNA export"
                     /db_xref="GeneID:56698"
                     /db_xref="MGI:MGI:1891839"
     exon            1..265
                     /gene="Phax"
                     /gene_synonym="2810055C14Rik; 4933427L19Rik; D18Ertd65e;
                     p55; Rnuxa"
                     /inference="alignment:Splign:2.1.0"
     CDS             170..1327
                     /gene="Phax"
                     /gene_synonym="2810055C14Rik; 4933427L19Rik; D18Ertd65e;
                     p55; Rnuxa"
                     /note="isoform 1 is encoded by transcript variant 1; RNA
                     U, small nuclear RNA export adaptor; phosphorylated
                     adapter RNA export protein; RNA U small nuclear RNA export
                     adapter protein; phosphorylation regulated"
                     /codon_start=1
                     /product="phosphorylated adapter RNA export protein
                     isoform 1"
                     /protein_id="NP_064380.3"
                     /db_xref="CCDS:CCDS29259.1"
                     /db_xref="GeneID:56698"
                     /db_xref="MGI:MGI:1891839"
                     /translation="MALEAGDMEEGQLSDSDSDMTVVPSDRPLQMAKVLGGGSAACAP
                     VSHYRTVKHVDSSEESLDSDDDCSLWKRKRQKCHNTPPKPEPFPFGPSGQKTALNGGK
                     KVNNIWGAVLQEQNQDAVATELGILGMEGSIDRSRQSETYNYLLAKKLAKKESQEYTK
                     ELDKDLDEYMHGDKKPGSKEDENGQGHLKRKRPVRDRLGNRVEMNYKGRYEITEEDAP
                     EKVADEIAFRLQEPKKDLIARVVRILGNKKAIELLMETAEVEQNGGLFIMNGSRRRTP
                     GGVFLNLLKNTPSISEEQIKDIFYVENQKEYENKKAARKRRTQLLGKKMKQAIKSLNF
                     QEDDDTSRETFASDTNEALASLDEAQEGPGETKLDAEEAIEVDHPQDLDIF"
     exon            266..852
                     /gene="Phax"
                     /gene_synonym="2810055C14Rik; 4933427L19Rik; D18Ertd65e;
                     p55; Rnuxa"
                     /inference="alignment:Splign:2.1.0"
     exon            853..973
                     /gene="Phax"
                     /gene_synonym="2810055C14Rik; 4933427L19Rik; D18Ertd65e;
                     p55; Rnuxa"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1057
                     /gene="Phax"
                     /gene_synonym="2810055C14Rik; 4933427L19Rik; D18Ertd65e;
                     p55; Rnuxa"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1893
                     /gene="Phax"
                     /gene_synonym="2810055C14Rik; 4933427L19Rik; D18Ertd65e;
                     p55; Rnuxa"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1350..1355
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Phax"
                     /gene_synonym="2810055C14Rik; 4933427L19Rik; D18Ertd65e;
                     p55; Rnuxa"
                     /note="hexamer: AATAAA"
     polyA_site      1372
                     /gene="Phax"
                     /gene_synonym="2810055C14Rik; 4933427L19Rik; D18Ertd65e;
                     p55; Rnuxa"
     regulatory      1663..1668
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Phax"
                     /gene_synonym="2810055C14Rik; 4933427L19Rik; D18Ertd65e;
                     p55; Rnuxa"
                     /note="hexamer: ATTAAA"
     polyA_site      1685
                     /gene="Phax"
                     /gene_synonym="2810055C14Rik; 4933427L19Rik; D18Ertd65e;
                     p55; Rnuxa"
                     /note="major polyA site"
ORIGIN      
        1 gcggaactcg cctcccagcg ctgagttttg tgatggtgac gctcgcccgg gcctgcggag
       61 gcgccgccct agcgctcgcc cgcacggggg cgccgcagca ccgccctaag gccttccctc
      121 ctccgccgcc cgccggaagc gctctcctga ccctgcgcgc cgcgggaaga tggcgctgga
      181 agctggcgac atggaagagg ggcagctttc cgactcggat tccgacatga cggtcgtccc
      241 cagcgatagg cctctgcaaa tggcgaaagt cctaggtggg ggcagcgctg cgtgcgcacc
      301 ggtgtcacat tatcggactg ttaaacatgt ggactccagc gaggagagtc tagattccga
      361 tgacgattgc tctctttgga aacgcaagcg acagaagtgt cataatactc ctcccaagcc
      421 agagcctttc ccatttggac caagtggtca gaaaacggct ctcaacggag gaaagaaggt
      481 gaacaacatc tggggcgcgg tgctccagga acagaatcaa gatgcggtgg ccactgaact
      541 cggcatcttg ggaatggaag gctccattga cagaagcagg cagtctgaga cctataacta
      601 tttgcttgct aagaaacttg ctaagaagga atctcaagag tacacaaagg aattagacaa
      661 agatctagat gaatatatgc atggtgacaa aaaaccaggg tcaaaggaag acgagaatgg
      721 gcaaggtcac ctcaagcgga aacgacctgt cagagacaga ctgggtaaca gagtggaaat
      781 gaactacaaa gggcgctatg agatcacaga agaggatgct cccgagaaag tagccgatga
      841 gatcgccttc aggttgcagg aacccaagaa ggacctgata gcccgagtag tgaggatact
      901 tgggaacaaa aaggccattg aacttctgat ggaaacagct gaagtcgagc aaaatggtgg
      961 tcttttcata atgaatggta gccgaagaag aacacccggt ggagtctttc tgaatctcct
     1021 gaagaacaca cccagcatca gcgaggaaca gattaaggac attttctacg ttgaaaatca
     1081 aaaggaatat gaaaataaaa aagctgctag aaaaagaaga acacagcttt tggggaagaa
     1141 aatgaaacaa gctattaaaa gtctgaactt ccaggaggac gatgacacat ctcgagaaac
     1201 gtttgcaagt gacactaatg aggccctggc ctctctcgac gaagcccagg aaggacctgg
     1261 cgagaccaag ctggatgctg aggaggccat tgaggtggac caccctcagg acttggacat
     1321 cttctgagca cactggggac attttgaaga ataaaccttt gtttaaaaag ttgttaccat
     1381 ttctactgag gttgctttac tgtgtactga gactagagaa aggggcgctg ttcctgtttc
     1441 tgtgtatgtg atgtatgtgg acaggggtgc gctcggcagc agcgtggagg gagggctgtg
     1501 tctctcggtg cacggcacgg gttaaatctc attctgtggc atgtgctgtc tgttagcctg
     1561 agtggggctg tgacctctgt tcagcccact gtttcatgcc attaagacac ttcggttttc
     1621 tgactcatct tggtgaacta tgctttggtt ttaacacatt ccattaaaat atcctgtaac
     1681 atgtataaat tgttcagctg ttacattcag taatgggaag ggtcttggtg tgggctgacc
     1741 cctcccacct cagcctgatc agggctgaga taggagctta ggccctgtgt ctactacttt
     1801 gtatcattct ttaaaacgtt aatttattac tgtgtgcatg agagaggagg tgtggaggcc
     1861 atgcttatgg tggttaaagg gcattttgtg gag
//
