LOCUS       NM_028132               2334 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus phosphoglucomutase 1 (Pgm1), mRNA.
ACCESSION   NM_028132
VERSION     NM_028132.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2334)
  AUTHORS   Balakrishnan,B., Altassan,R., Budhraja,R., Liou,W., Lupo,A.,
            Bryant,S., Mankouski,A., Radenkovic,S., Preston,G.J., Pandey,A.,
            Boudina,S., Kozicz,T., Morava-Kozicz,E. and Lai,K.
  TITLE     AAV-based gene therapy prevents and halts the progression of
            dilated cardiomyopathy in a mouse model of phosphoglucomutase 1
            deficiency (PGM1-CDG)
  JOURNAL   Transl Res 257, 1-14 (2023)
   PUBMED   36709920
REFERENCE   2  (bases 1 to 2334)
  AUTHORS   Conte,F., Ashikov,A., Mijdam,R., van de Ven,E.G.P., van
            Scherpenzeel,M., Veizaj,R., Mahalleh-Yousefi,S.P., Post,M.A.,
            Huijben,K., Panneman,D.M., Rodenburg,R.J.T., Voermans,N.C.,
            Garanto,A., Koopman,W.J.H., Wessels,H.J.C.T., Noga,M.J. and
            Lefeber,D.J.
  TITLE     In Vitro Skeletal Muscle Model of PGM1 Deficiency Reveals Altered
            Energy Homeostasis
  JOURNAL   Int J Mol Sci 24 (9), 8247 (2023)
   PUBMED   37175952
  REMARK    GeneRIF: In Vitro Skeletal Muscle Model of PGM1 Deficiency Reveals
            Altered Energy Homeostasis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2334)
  AUTHORS   Roberts,G.A.G. and Tunster,S.J.
  TITLE     Characterising the dynamics of placental glycogen stores in the
            mouse
  JOURNAL   Placenta 99, 131-140 (2020)
   PUBMED   32798765
REFERENCE   4  (bases 1 to 2334)
  AUTHORS   Balakrishnan,B., Verheijen,J., Lupo,A., Raymond,K., Turgeon,C.,
            Yang,Y., Carter,K.L., Whitehead,K.J., Kozicz,T., Morava,E. and
            Lai,K.
  TITLE     A novel phosphoglucomutase-deficient mouse model reveals aberrant
            glycosylation and early embryonic lethality
  JOURNAL   J Inherit Metab Dis 42 (5), 998-1007 (2019)
   PUBMED   31077402
REFERENCE   5  (bases 1 to 2334)
  AUTHORS   Zurkirchen,L., Varum,S., Giger,S., Klug,A., Hausel,J., Bossart,R.,
            Zemke,M., Cantu,C., Atak,Z.K., Zamboni,N., Basler,K. and Sommer,L.
  TITLE     Yin Yang 1 sustains biosynthetic demands during brain development
            in a stage-specific manner
  JOURNAL   Nat Commun 10 (1), 2192 (2019)
   PUBMED   31097699
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2334)
  AUTHORS   Lalley,P.A., Minna,J.D. and Francke,U.
  TITLE     Conservation of autosomal gene synteny groups in mouse and man
  JOURNAL   Nature 274 (5667), 160-163 (1978)
   PUBMED   662012
REFERENCE   7  (bases 1 to 2334)
  AUTHORS   Lalley,P.A., Francke,U. and Minna,J.D.
  TITLE     Homologous genes for enolase, phosphogluconate dehydrogenase,
            phosphoglucomutase, and adenylate kinase are syntenic on mouse
            chromosome 4 and human chromosome 1p
  JOURNAL   Proc Natl Acad Sci U S A 75 (5), 2382-2386 (1978)
   PUBMED   209463
REFERENCE   8  (bases 1 to 2334)
  AUTHORS   Francke,U., Lalley,P.A., Moss,W., Ivy,J. and Minna,J.D.
  TITLE     Gene mapping in Mus musculus by interspecific cell hybridization:
            assignment of the genes for tripeptidase-1 to chromosome 10,
            dipeptidase-2 to chromosome 18, acid phosphatase-1 to chromosome
            12, and adenylate kinase-1 to chromosome 2
  JOURNAL   Cytogenet Cell Genet 19 (2-3), 57-84 (1977)
   PUBMED   198184
REFERENCE   9  (bases 1 to 2334)
  AUTHORS   Krog,H.H., Wysocka,M., Kisielow,P. and Radzikowski,C.
  TITLE     Genetic characterization of important mouse strains used in cancer
            research
  JOURNAL   Hereditas 87 (2), 201-204 (1977)
   PUBMED   75870
REFERENCE   10 (bases 1 to 2334)
  AUTHORS   Chapman,V.M.
  TITLE     6-Phosphogluconate dehydrogenase (PGD) genetics in the mouse:
            linkage with metabolically related enzyme loci
  JOURNAL   Biochem Genet 13 (11-12), 849-856 (1975)
   PUBMED   1200981
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK152923.1 and AK147982.1.
            
            [WARNING] On Apr 15, 2024 this sequence was replaced by
            NM_028132.4.
            
            On Apr 22, 2009 this sequence version replaced NM_028132.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC080801.1, SRR1660821.94549.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                AK152923.1         1-29
            30-2334             AK147982.1         2-2306
FEATURES             Location/Qualifiers
     source          1..2334
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 45.71 cM"
     gene            1..2334
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /note="phosphoglucomutase 1"
                     /db_xref="GeneID:72157"
                     /db_xref="MGI:MGI:97565"
     exon            1..361
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..1804
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /EC_number="5.4.2.2"
                     /note="glucose phosphomutase 1; phosphoglucomutase 2"
                     /codon_start=1
                     /product="phosphoglucomutase-1"
                     /protein_id="NP_082408.3"
                     /db_xref="CCDS:CCDS18388.1"
                     /db_xref="GeneID:72157"
                     /db_xref="MGI:MGI:97565"
                     /translation="MVKIVTVKTQAYPDQKPGTSGLRKRVKVFQSNANYAENFIQSIV
                     STVEPALRQEATLVVGGDGRFYMTEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSCI
                     IRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAIC
                     PDLKVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRNIFDFNALKELLSGPNRL
                     KIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETM
                     KSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARS
                     MPTSGALDRVANATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGL
                     WAVLAWLSILATRKQSVEDILKDHWQKFGRNFFTRYDYEEVEAEGANKMMKDLEALML
                     DRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISKNQGLRLIFADGSRIIFRLSGTG
                     SAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT"
     exon            362..524
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /inference="alignment:Splign:2.1.0"
     exon            525..671
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /inference="alignment:Splign:2.1.0"
     exon            672..797
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /inference="alignment:Splign:2.1.0"
     exon            798..988
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1143
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1259
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1395
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1579
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /inference="alignment:Splign:2.1.0"
     exon            1580..1714
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /inference="alignment:Splign:2.1.0"
     exon            1715..2334
                     /gene="Pgm1"
                     /gene_synonym="2610020G18Rik; Pgm-2; Pgm1a; Pgm2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgggccgt gggcaggccc tgggccatcg tttccagggc aagagcagag cggaccctga
       61 gccctctgca gcagccagag ccgcagccac tgtcgcctcg cagccaaccg ccaccatggt
      121 gaagatcgtg acagtgaaga cgcaggcata tccggatcag aagccgggca ccagcggatt
      181 gcggaagcga gtgaaggttt tccagagcaa cgccaactat gcggagaatt tcatccagag
      241 catcgtctct accgtggagc cggcgctgag gcaggaggcc acgctggttg tgggcgggga
      301 cggccgcttc tacatgaccg aggccatcca gctcatcgta cgcatcgctg cagccaacgg
      361 gattggtcgc ctggttattg ggcagaatgg aatactctcc acccctgccg tatcttgcat
      421 catccgaaaa atcaaagcta ttggtgggat cattctgaca gccagccata atccaggagg
      481 gcccaatgga gattttggaa ttaaattcaa tatttctaat gggggtcctg ctccagaagc
      541 aatcactgat aaaattttcc aaatcagcaa gacaatcgaa gaatatgcca tttgccctga
      601 cttgaaggta gacctcggtg ttctgggaaa gcagcagttt gacttggaaa acaagttcaa
      661 gcccttcaca gtggagattg tggactcagt ggaggcctat gccacaatgc tgagaaacat
      721 cttcgatttc aacgcactga aggagctact ctctggtcca aacagactga agatccgcat
      781 agacgccatg cacggagttg tgggaccgta cgtaaagaag atcctctgtg aagaacttgg
      841 tgcccctgca aactcagctg tgaactgtgt tcccctggag gattttggag gccaccatcc
      901 cgaccccaat ctcacctatg ctgctgacct agtggagacc atgaagtcag gagagcatga
      961 tttcggggct gcctttgatg gtgacgggga tcgaaacatg attctgggca agcacgggtt
     1021 ctttgtgaat ccttctgact ctgtggctgt catcgctgcc aacatcttca gcattccgta
     1081 cttccagcag accggggtcc gtggctttgc acgcagcatg cccacaagtg gtgctctgga
     1141 ccgggtagca aatgccacaa agatcgcttt gtatgagacc ccaactggct ggaagttttt
     1201 tgggaatttg atggatgcaa gcaagctgtc cctctgtgga gaggagagct ttgggaccgg
     1261 ttcggaccat atccgagaga aagatggact gtgggccgtc ctggcctggc tctccattct
     1321 ggccacccgc aaacagagcg tggaggacat cctcaaagac cactggcaga agtttggtcg
     1381 gaacttcttt accaggtatg actacgagga ggtggaagct gagggtgcaa acaaaatgat
     1441 gaaggacctg gaggccctga tgctggaccg ctcctttgtg gggaagcagt tctcagcaaa
     1501 cgataaagtc tacactgtgg agaaagcgga taactttgaa tatagtgacc cagtagatgg
     1561 aagcatttca aaaaatcagg gcttgcggct tatttttgca gatggttctc gtatcatctt
     1621 cagactgagt ggcaccggga gtgcaggggc taccatccgg ctgtatattg atagctacga
     1681 gaaggacgtt gccaagatca accaggaccc ccaggtgatg ctggcgcccc tgatctccat
     1741 tgctctgaaa gtgtcccagc tccaggagag gacgggtcgc actgcgccca ctgtcatcac
     1801 ctagaaagat ggccagatgt ggcacgtccc tcccccagga ctatccacgc cacctgattg
     1861 aagagcacgg acagaaacag tgtatttgcc tgggcctttt aggactcggt cttgattttt
     1921 tacttcccac tttgataaac agccatttgt gaggcactgc cactgtgtgg gggagaggga
     1981 aagcagaccc gagggcctgc acctgtgtct gttccttctc ttgccctatt aaattgctgc
     2041 tgtgtgagcc cttgtctccc tacatcaggt acagtacact acactgtaaa gatttggagg
     2101 tggagggtca gcaacaaggc catctcctgt ccatggagtg tgcctgtaaa atgatatcaa
     2161 agttcctgct tcactgtgaa agtctcccca tgtgtgttta catgtaatcc aacagaatac
     2221 ggttcctggt gccttctctc tgagtgagat gtgcttgcct tcagacctct gtgttatttt
     2281 gcatctccca tctgcacaga tatttggggt attaaagcag aatgtgctac ggtt
//
