LOCUS       NM_001033537            2424 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus post-GPI attachment to proteins 3 (Pgap3), mRNA.
ACCESSION   NM_001033537 XM_354640 XM_895146 XM_903034 XM_915283 XM_923647
            XM_923653
VERSION     NM_001033537.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2424)
  AUTHORS   Wang,Y., Murakami,Y., Yasui,T., Wakana,S., Kikutani,H.,
            Kinoshita,T. and Maeda,Y.
  TITLE     Significance of glycosylphosphatidylinositol-anchored protein
            enrichment in lipid rafts for the control of autoimmunity
  JOURNAL   J Biol Chem 288 (35), 25490-25499 (2013)
   PUBMED   23864655
REFERENCE   2  (bases 1 to 2424)
  AUTHORS   Murakami,H., Wang,Y., Hasuwa,H., Maeda,Y., Kinoshita,T. and
            Murakami,Y.
  TITLE     Enhanced response of T lymphocytes from Pgap3 knockout mouse:
            Insight into roles of fatty acid remodeling of GPI anchored
            proteins
  JOURNAL   Biochem Biophys Res Commun 417 (4), 1235-1241 (2012)
   PUBMED   22227195
  REMARK    GeneRIF: the response of T cells was enhanced in Pgap3 knockout
            mice in both in vitro and in vivo studies, including alloreactive
            response, antigen-specific immune response, and experimental
            autoimmune encephalomyelitis.
REFERENCE   3  (bases 1 to 2424)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591390.8.
            
            On Sep 14, 2006 this sequence version replaced NM_001033537.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK078974.1, AK170817.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-276               AL591390.8         105079-105354
            277-374             AL591390.8         106587-106684
            375-527             AL591390.8         107521-107673
            528-590             AL591390.8         113812-113874
            591-652             AL591390.8         114428-114489
            653-789             AL591390.8         114756-114892
            790-994             AL591390.8         115078-115282
            995-2424            AL591390.8         115468-116897
FEATURES             Location/Qualifiers
     source          1..2424
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 61.75 cM"
     gene            1..2424
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /note="post-GPI attachment to proteins 3"
                     /db_xref="GeneID:320655"
                     /db_xref="MGI:MGI:2444461"
     exon            1..276
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..1058
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /note="per1-like domain containing 1; post-GPI attachment
                     to proteins factor 3; PER1-like domain-containing protein
                     1"
                     /codon_start=1
                     /product="post-GPI attachment to proteins factor 3
                     precursor"
                     /protein_id="NP_001028709.2"
                     /db_xref="CCDS:CCDS25348.1"
                     /db_xref="GeneID:320655"
                     /db_xref="MGI:MGI:2444461"
                     /translation="MAKRTAPLLLLTLAVGLAGGSQGDREPVYRDCVLRCEERNCSGD
                     ALKHFRSRQPIYMSLAGWTCRDDCKYECMWFTVGLYLQEGHRVPQFHGKWPFSRFLFI
                     QEPASAVASLLNGLASLVMLCRYRASVPASSPMYHTCMAFAWVSLNAWFWSTVFHTRD
                     TDLTEKMDYFCASAVILHSVYLCCVRTVGLQHPSVASAFGALLLLLLTGHISYLSLVH
                     FDYGYNMMANVAIGLVNLAWWLVWCLRNRQRLPHTRRCMVVVVLLQGLSLLELLDFPP
                     LFWVLDAHAIWHISTIPVHTLFFRFLEDDSLYLLKESGAMFKLD"
     exon            277..374
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /inference="alignment:Splign:2.1.0"
     exon            375..527
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /inference="alignment:Splign:2.1.0"
     exon            528..590
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /inference="alignment:Splign:2.1.0"
     exon            591..652
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /inference="alignment:Splign:2.1.0"
     exon            653..789
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /inference="alignment:Splign:2.1.0"
     exon            790..994
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /inference="alignment:Splign:2.1.0"
     exon            995..2424
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2394..2399
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /note="hexamer: AATAAA"
     polyA_site      2419
                     /gene="Pgap3"
                     /gene_synonym="CAB2; D430035D22Rik; Perld1"
                     /note="major polyA site"
ORIGIN      
        1 gatgcaacga tgaacacagg tacttccggt tgttacggaa gtgggacttc gtcttctccc
       61 aagctcctcc ctcagcggcc gggcacagtg acagaatggc caagcggacg gcgccgctgc
      121 tgctgctaac cttggcagtg ggactcgcgg ggggttccca gggcgaccgc gagcccgtgt
      181 accgcgactg cgtgctccga tgcgaggaac ggaactgttc gggagacgca ctgaagcact
      241 tccgctcccg ccagccaatc tacatgagcc tagctggctg gacctgtcgg gacgactgca
      301 agtatgagtg tatgtggttc actgttggcc tctaccttca ggagggccac agagtgcctc
      361 agttccatgg caagtggccc ttctcccggt tcctgttcat ccaagagcca gcttctgccg
      421 tggcctcact cctcaatggc ctggccagcc tggtgatgct ctgccgctat cgcgcctctg
      481 tgccagcctc ctcccccatg taccatacct gcatggcctt cgcttgggtg tctctcaatg
      541 cttggttctg gtccacagtc ttccatacca gggacactga cctcacagag aagatggact
      601 acttctgcgc ttcagctgtc atcctgcatt ctgtttacct gtgctgtgtc aggaccgtgg
      661 gactacagca cccgtctgtg gccagtgcct tcggtgccct gctgctgctg ctgctgacag
      721 gacacatatc ctacctgagc cttgtccatt tcgactacgg ctacaacatg atggccaacg
      781 tggctatcgg cctggtgaac ctggcgtggt ggctggtctg gtgcctacgg aaccgccagc
      841 gcctccctca cacccgcagg tgtatggtgg tggtagtgct gctgcagggg ctgtccctgc
      901 tggaattgct tgacttcccg cccctcttct gggtcctgga cgcccacgcc atctggcaca
      961 tcagcaccat cccggtccac accctctttt tcaggtttct ggaagatgac agcttgtacc
     1021 tactgaagga atctggagcc atgttcaagc tggactaaag aggctgggag agagtggctc
     1081 catccgcctc gtccctgagg cgtctcaggg catctccctt ctcccccccc ccccttgaga
     1141 tgattggctt ttcccctttt agcttcctga acttgattat gtggggtttg gacctgaaat
     1201 cctgtagcta cctggccctt gctggccttc acatggaacc tgtcttgggg gcggcctccc
     1261 cacatctggg gcagggacta ggcagctgtc cggtggctgg gcctgaacgg agaccaagtt
     1321 tagaggttca cagagaggag gagggctgcg tctatattcc ccaacccctc cctttccaca
     1381 tcactcaccc ccatagtgcc accccaagta cctccactta ccccccaaac cacacccaca
     1441 ggcctttggg gttcgttggg atctcttttt gtcagggcac actaggtggc gctggatgct
     1501 tgcttctcag ctgcccaggt ttctctccag ctctgaggaa ccgggctcct tgggtaggag
     1561 gggtttctac cctgcctccc acaacccagc caggaccccg ggaagctcag gatcagaacc
     1621 cagtctgctg ttctgactgg gagtggacac attgacacat agagggctat gggccaagcc
     1681 aggggcagag atgaccatgt ggccagtgag ctggggcact gtgggtcttc acttagagtg
     1741 tactgcagtt cagggggcag ggcgctgagg tggtttgggg aaggtatgtg taagagatga
     1801 acatgcaccg gatacgctgg taggaggcgg aagcagaact ctggaatcaa gtcatcaaca
     1861 gtcactggaa ctccaagtct gccccaggcc ccaaggccat ccagctgcta ggatatacac
     1921 atgacctgat agactttggg atgctgggtg ggagtgtggg tgcccaccca gtgccccctt
     1981 tgcactccac tcaaatcaca tacctccccc cacgtcttga gagcgccctg cagaactagc
     2041 tccccccccc ccaaggcagg gaggcggagg gggaagtacc cactcctgcc ccctggttct
     2101 ttatcttggg atggtggacc tcccactcag ttccctttgt cagagctgga ctctccccgg
     2161 ccaatcccag ggcaagcagg gcccattcag cctgtatcct gaaccaaccc atcaggaagg
     2221 ctgtctgcag ttgagccctg cctctgtcct ctaccccctc tttgcggggg aggatagcta
     2281 tgccaaggct ccagctcagg tacttaggca gcctattagg gttttggttt ttgttttgtt
     2341 ttggttttgt actaagaata attttaaggc cggaggcagg aaagggcatg cttaataaag
     2401 caactcctgg cctccctcac cctg
//
