LOCUS       NM_026027               1077 bp    mRNA    linear   ROD 29-OCT-2024
DEFINITION  Mus musculus prefoldin 1 (Pfdn1), mRNA.
ACCESSION   NM_026027
VERSION     NM_026027.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1077)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1077)
  AUTHORS   Yagi,H., Oka,Y., Komada,M., Xie,M.J., Noguchi,K. and Sato,M.
  TITLE     Filamin A interacting protein plays a role in proper positioning of
            callosal projection neurons in the cortex
  JOURNAL   Neurosci Lett 612, 18-24 (2016)
   PUBMED   26655467
REFERENCE   3  (bases 1 to 1077)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (bases 1 to 1077)
  AUTHORS   Cao,S., Carlesso,G., Osipovich,A.B., Llanes,J., Lin,Q., Hoek,K.L.,
            Khan,W.N. and Ruley,H.E.
  TITLE     Subunit 1 of the prefoldin chaperone complex is required for
            lymphocyte development and function
  JOURNAL   J Immunol 181 (1), 476-484 (2008)
   PUBMED   18566413
  REMARK    GeneRIF: Pfdn1-deficient mice displayed phenotypes characteristic
            of defects in cytoskeletal function, including manifestations of
            ciliary dyskinesia, neuronal loss, and defects in B and T cell
            development and function
REFERENCE   5  (bases 1 to 1077)
  AUTHORS   Yoshikawa,T., Piao,Y., Zhong,J., Matoba,R., Carter,M.G., Wang,Y.,
            Goldberg,I. and Ko,M.S.
  TITLE     High-throughput screen for genes predominantly expressed in the ICM
            of mouse blastocysts by whole mount in situ hybridization
  JOURNAL   Gene Expr Patterns 6 (2), 213-224 (2006)
   PUBMED   16325481
REFERENCE   6  (bases 1 to 1077)
  AUTHORS   Lin,Q., Donahue,S.L., Moore-Jarrett,T., Cao,S., Osipovich,A.B. and
            Ruley,H.E.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
REFERENCE   7  (bases 1 to 1077)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC147220.3 and
            AC130714.3.
            
            On Apr 29, 2007 this sequence version replaced NM_026027.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK012575.1, CK626698.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                AC147220.3         119736-119778       c
            44-210              AC147220.3         116363-116529       c
            211-295             AC147220.3         97589-97673         c
            296-1077            AC130714.3         4535-5316
FEATURES             Location/Qualifiers
     source          1..1077
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 19.46 cM"
     gene            1..1077
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
                     /note="prefoldin 1"
                     /db_xref="GeneID:67199"
                     /db_xref="MGI:MGI:1914449"
     exon            1..43
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             11..379
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
                     /codon_start=1
                     /product="prefoldin subunit 1"
                     /protein_id="NP_080303.1"
                     /db_xref="CCDS:CCDS29152.1"
                     /db_xref="GeneID:67199"
                     /db_xref="MGI:MGI:1914449"
                     /translation="MAASVDLELKKAFTELQAKVIDTQQKVKLADIQIEQLNRTKKHA
                     HLTDTEIMTLVDETNMYEGVGRMFILQSKEVIHNQLLEKQKIAEEKIKELEQKKSYLE
                     RSVKEAEDNIREMLMARRAQ"
     exon            44..210
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            211..295
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            296..1077
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      649..654
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
                     /note="hexamer: AATAAA"
     polyA_site      673
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
                     /note="major polyA site"
     regulatory      867..872
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
                     /note="hexamer: AACAAA"
     polyA_site      890
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
     regulatory      1059..1064
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
                     /note="hexamer: AGTAAA"
     polyA_site      1077
                     /gene="Pfdn1"
                     /gene_synonym="2700086I23Rik"
ORIGIN      
        1 gtgctccaat atggccgcct ccgtggatct ggagttgaag aaggccttca cagagcttca
       61 agccaaagtt atcgatactc aacagaaggt gaagcttgca gacatacaga ttgaacagct
      121 gaacagaacg aaaaagcacg cacaccttac ggacacggag atcatgacgc tggtagatga
      181 gactaacatg tacgaaggtg taggaagaat gtttattcta cagtccaagg aagtaattca
      241 caaccagctg ttagaaaaac agaaaatagc agaagaaaaa attaaagagc tggagcagaa
      301 gaaatcctac ctggagcgga gcgtcaagga ggctgaggac aacatccggg agatgctgat
      361 ggcgcggagg gcacagtagg agctgctggg aagcgccttc cgttctgatc cctcacatcc
      421 tgtcacggca ggggctgtgc agggtactgc cctccctctg cccagcagcc ccatctctcc
      481 atcaccctga gcccctcagg tcccaactga atgtctgcca acccctgctc aggacactct
      541 tctttcctgg ggcaagccag gagctctcaa cagagggagg actggagggc agatggagaa
      601 agctgtccaa gcctgtcact aggcatgtgg gttagaccag gttagaccaa taaaaagcta
      661 tgtctttact ttatggcatg tgcttttctc caccggagga gagagaggca agtgtctccc
      721 tcagcttgtg tccctttttt cctccccttt ctgtcctggg cctctgtgta gagcatggag
      781 gaagaagacg acaagttgat aggtgtggtg gacagaggca cagttggctt cagggttcct
      841 tccctgtttt ctccccagaa ttctaaaaca aagttcagtg gcgagcagca tctctaggct
      901 ctggtcctgt ctggccatgg tgcgcccgtg gccctgcctc ctagtgctca ggacagctca
      961 ttctctgtgc aactttcagg aactttactg caggtcagtt aaacacaact gttactgaaa
     1021 actagatgta aacttaagta tttagaacaa aaactactag taaatactca gaactcc
//
