LOCUS       NM_145122               1470 bp    mRNA    linear   ROD 17-DEC-2022
DEFINITION  Mus musculus peroxisomal biogenesis factor 16 (Pex16), transcript
            variant 1, mRNA.
ACCESSION   NM_145122
VERSION     NM_145122.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1470)
  AUTHORS   Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang
            X, Hsu FF, Razani B, Funai K and Lodhi IJ.
  TITLE     Peroxisome-derived lipids regulate adipose thermogenesis by
            mediating cold-induced mitochondrial fission
  JOURNAL   J Clin Invest 129 (2), 694-711 (2019)
   PUBMED   30511960
REFERENCE   2  (bases 1 to 1470)
  AUTHORS   Fratta P, Sivakumar P, Humphrey J, Lo K, Ricketts T, Oliveira H,
            Brito-Armas JM, Kalmar B, Ule A, Yu Y, Birsa N, Bodo C, Collins T,
            Conicella AE, Mejia Maza A, Marrero-Gagliardi A, Stewart M, Mianne
            J, Corrochano S, Emmett W, Codner G, Groves M, Fukumura R, Gondo Y,
            Lythgoe M, Pauws E, Peskett E, Stanier P, Teboul L, Hallegger M,
            Calvo A, Chio A, Isaacs AM, Fawzi NL, Wang E, Housman DE, Baralle
            F, Greensmith L, Buratti E, Plagnol V, Fisher EM and
            Acevedo-Arozena A.
  TITLE     Mice with endogenous TDP-43 mutations exhibit gain of splicing
            function and characteristics of amyotrophic lateral sclerosis
  JOURNAL   EMBO J 37 (11) (2018)
   PUBMED   29764981
REFERENCE   3  (bases 1 to 1470)
  AUTHORS   Kikuchi M, Hatano N, Yokota S, Shimozawa N, Imanaka T and Taniguchi
            H.
  TITLE     Proteomic analysis of rat liver peroxisome: presence of
            peroxisome-specific isozyme of Lon protease
  JOURNAL   J Biol Chem 279 (1), 421-428 (2004)
   PUBMED   14561759
REFERENCE   4  (bases 1 to 1470)
  AUTHORS   South ST and Gould SJ.
  TITLE     Peroxisome synthesis in the absence of preexisting peroxisomes
  JOURNAL   J Cell Biol 144 (2), 255-266 (1999)
   PUBMED   9922452
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL731709.19, AK143073.1 and BE690943.1.
            
            [WARNING] On May 3, 2023 this sequence was replaced by NM_145122.3.
            
            On Jul 28, 2009 this sequence version replaced NM_145122.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the functional protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143073.1, BC010822.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-278               AL731709.19        157017-157294
            279-1455            AK143073.1         281-1457
            1456-1470           BE690943.1         1-15                c
FEATURES             Location/Qualifiers
     source          1..1470
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2"
     gene            1..1470
                     /gene="Pex16"
                     /note="peroxisomal biogenesis factor 16"
                     /db_xref="GeneID:18633"
                     /db_xref="MGI:MGI:1338829"
     exon            1..437
                     /gene="Pex16"
                     /inference="alignment:Splign:2.1.0"
     CDS             326..1336
                     /gene="Pex16"
                     /note="peroxisomal membrane protein PEX16; peroxin-16"
                     /codon_start=1
                     /product="peroxisomal biogenesis factor 16"
                     /protein_id="NP_660104.2"
                     /db_xref="CCDS:CCDS16444.1"
                     /db_xref="GeneID:18633"
                     /db_xref="MGI:MGI:1338829"
                     /translation="MEKLRLLSLRYQEYVTRHPAATAQLETAVRGLSYLLAGRFSDSH
                     ELSELVYSASNLLVLLNDGILRKELRKKLPVSLSQQKLLTWLSVLECVEVFMEMGAAK
                     VWGEVGRWLVIALIQLAKAVLRMLLLIWFKAGIQTSPPIVPLDRETQAQPLDGDHNPG
                     SQEPSYVGKRSHRVVRTLQNSPSLHSRYWGAPQQREIRQKQQQEELSTPPTPLGLQET
                     IAESLYIARPLLHLLSLGLWGQRSWTPWLLSGVVDMTSLSLLSDRKNLTRRERLELRR
                     RTILLLYYLLRSPFYDRFSEAKILFLLQLLTDHIPGVGLVARPLMDYLPSWQKIYFYS
                     WG"
     exon            438..473
                     /gene="Pex16"
                     /inference="alignment:Splign:2.1.0"
     exon            474..550
                     /gene="Pex16"
                     /inference="alignment:Splign:2.1.0"
     exon            551..684
                     /gene="Pex16"
                     /inference="alignment:Splign:2.1.0"
     exon            685..785
                     /gene="Pex16"
                     /inference="alignment:Splign:2.1.0"
     exon            786..866
                     /gene="Pex16"
                     /inference="alignment:Splign:2.1.0"
     exon            867..1019
                     /gene="Pex16"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1092
                     /gene="Pex16"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1212
                     /gene="Pex16"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1277
                     /gene="Pex16"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1462
                     /gene="Pex16"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagttgtaac tacgcaggcg ccaagacagc caaccaagga ggctgcagat cgggtgccag
       61 aagctctaga gagcttcagg gcggagagag aaggagccaa tggctggaag gagggagggt
      121 gggagctccc ggtctcgggg aggaggcgct agagatgggg tgaaggggcg ttcaggggct
      181 ccgcgggtct aagtcctcct gggctgcgga agttgagcaa ccgggaggcg ggcttagggc
      241 cggaagcagg aaggagggct caggacgcag ggcgccgctg ccagccttgc tgtcggccgg
      301 tgggactgtc agtggccaga gcaggatgga gaagctacgg ctcctgagcc tccgctacca
      361 ggagtatgtg actcgtcatc cagccgccac ggcccagttg gagacggctg tgcggggcct
      421 cagttacctg ctggcaggtc gcttctccga ttcacacgag ctgtctgaac tggtgtactc
      481 tgcctcgaac ctgctggtgc tgctcaatga cgggatcctg aggaaggagc ttcgaaaaaa
      541 gttgcctgtg tcgctgtccc agcagaagtt gctgacatgg ctgagtgtac tggagtgtgt
      601 ggaggtgttc atggagatgg gggctgccaa ggtgtggggc gaagtaggcc gttggctcgt
      661 cattgctctc atccagttgg ccaaggccgt cctgcgcatg ctcctgttga tctggttcaa
      721 ggctggcatt cagacatcac cccccattgt tccactggac agggaaactc aggcacagcc
      781 cttggatggt gaccacaatc cgggcagcca ggagccatca tatgtgggga aacggtcaca
      841 cagagtggtg cgaaccctcc agaacagccc atccctgcac tcacggtact ggggagcccc
      901 tcagcagcgg gaaattcggc agaaacagca gcaggaggaa ctgagcacac ccccaacacc
      961 tctggggttg caggagacca ttgcagagtc tttgtacatc gcccggcccc tgctgcactt
     1021 gctcagcctg ggcttatggg gtcagcgatc gtggacaccc tggctactgt ctggtgtggt
     1081 agatatgact agcctgagtc tcctgagtga caggaagaac ttgacccgga gggagcggct
     1141 agaactgagg cgtcgcacaa tcctgctgct atactacctg ctacgctcac cgttctatga
     1201 ccgcttctct gaagccaaga tcctcttcct gctccagctg cttacagacc acatccctgg
     1261 cgtgggtctg gtggcaaggc cgctcatgga ctacttgccc tcctggcaga aaatctattt
     1321 ctacagttgg ggctgacagc catgagggag ctggggcaga gggccatgtg ctgtgctctg
     1381 ctgctctggg cagggcccct cagccctcca gttcccccag gcccctcttc tctaataaac
     1441 ctgactctgg tagtgtccag caaaaaaaaa
//
