LOCUS       NM_026951               2838 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus peroxisomal biogenesis factor 11 gamma (Pex11g),
            transcript variant 2, mRNA.
ACCESSION   NM_026951
VERSION     NM_026951.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2838)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2838)
  AUTHORS   Li,X., Baumgart,E., Dong,G.X., Morrell,J.C., Jimenez-Sanchez,G.,
            Valle,D., Smith,K.D. and Gould,S.J.
  TITLE     PEX11alpha is required for peroxisome proliferation in response to
            4-phenylbutyrate but is dispensable for peroxisome
            proliferator-activated receptor alpha-mediated peroxisome
            proliferation
  JOURNAL   Mol Cell Biol 22 (23), 8226-8240 (2002)
   PUBMED   12417726
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC169677.2.
            
            On Feb 9, 2019 this sequence version replaced NM_026951.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024096.1, AK007582.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-77                AC169677.2         9964-10040
            78-266              AC169677.2         11641-11829
            267-445             AC169677.2         13512-13690
            446-508             AC169677.2         17278-17340
            509-2838            AC169677.2         18178-20507
FEATURES             Location/Qualifiers
     source          1..2838
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 1.92 cM"
     gene            1..2838
                     /gene="Pex11g"
                     /gene_synonym="1810022F11Rik; 1810049N02Rik; Pex11c;
                     Pex11gamma"
                     /note="peroxisomal biogenesis factor 11 gamma"
                     /db_xref="GeneID:69129"
                     /db_xref="MGI:MGI:1920905"
     exon            1..77
                     /gene="Pex11g"
                     /gene_synonym="1810022F11Rik; 1810049N02Rik; Pex11c;
                     Pex11gamma"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..743
                     /gene="Pex11g"
                     /gene_synonym="1810022F11Rik; 1810049N02Rik; Pex11c;
                     Pex11gamma"
                     /note="isoform 2 is encoded by transcript variant 2;
                     peroxisomal biogenesis factor 11c; peroxisomal membrane
                     protein 11C; PEX11-gamma; peroxin-11C; protein PEX11
                     homolog gamma"
                     /codon_start=1
                     /product="peroxisomal membrane protein 11C isoform 2"
                     /protein_id="NP_081227.1"
                     /db_xref="CCDS:CCDS22061.1"
                     /db_xref="GeneID:69129"
                     /db_xref="MGI:MGI:1920905"
                     /translation="MALLNRLASALESHRVRDRLIRTLGYCCQLIGGVLVEQCPNRSE
                     VGRRLLVVSAQFNHCRTVLRLFDDLAMFVYTKQYGLGTKEEDIFIRWLSVLSNVTDQL
                     YYPCEHIAWAADAKVLRVDSAWWWTLNTALWTLSLLLGAVKALWTMLKLRQKLRSPTG
                     TSASQLPRSKRRAMEARICSEVLTLLSNLADLANAVHWLPRGVLWAGRFPPWLVGLMG
                     TISSILSTCQAVRAGRQAEADSP"
     exon            78..266
                     /gene="Pex11g"
                     /gene_synonym="1810022F11Rik; 1810049N02Rik; Pex11c;
                     Pex11gamma"
                     /inference="alignment:Splign:2.1.0"
     exon            267..445
                     /gene="Pex11g"
                     /gene_synonym="1810022F11Rik; 1810049N02Rik; Pex11c;
                     Pex11gamma"
                     /inference="alignment:Splign:2.1.0"
     exon            446..508
                     /gene="Pex11g"
                     /gene_synonym="1810022F11Rik; 1810049N02Rik; Pex11c;
                     Pex11gamma"
                     /inference="alignment:Splign:2.1.0"
     exon            509..2838
                     /gene="Pex11g"
                     /gene_synonym="1810022F11Rik; 1810049N02Rik; Pex11c;
                     Pex11gamma"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1106..1111
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pex11g"
                     /gene_synonym="1810022F11Rik; 1810049N02Rik; Pex11c;
                     Pex11gamma"
                     /note="hexamer: ATTAAA"
     polyA_site      1127
                     /gene="Pex11g"
                     /gene_synonym="1810022F11Rik; 1810049N02Rik; Pex11c;
                     Pex11gamma"
                     /note="major polyA site"
     regulatory      2817..2822
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pex11g"
                     /gene_synonym="1810022F11Rik; 1810049N02Rik; Pex11c;
                     Pex11gamma"
                     /note="hexamer: AATAAA"
     polyA_site      2838
                     /gene="Pex11g"
                     /gene_synonym="1810022F11Rik; 1810049N02Rik; Pex11c;
                     Pex11gamma"
ORIGIN      
        1 gtcacgaccg agttgccatg gctctgctga accgtctggc ttccgcgctg gagtcccacc
       61 gggtccggga ccgcctgatc cggacactgg ggtattgctg ccagctgatc ggtggggtcc
      121 tagtggaaca atgccccaac aggtccgaag tgggaaggcg cttgctggtg gtgtcagccc
      181 agttcaatca ttgcaggact gtcttgagac tctttgatga cctggccatg tttgtctaca
      241 ctaagcagta tggcctggga acaaaggagg aggacatctt catccgatgg ctgtctgtcc
      301 tgagtaatgt gactgaccaa ctgtactatc cttgtgagca tatcgcctgg gctgccgatg
      361 ccaaggtcct ccgggtggac tctgcttggt ggtggacact gaacacagcc ctctggactc
      421 tctctctact tcttggagct gtcaaggccc tgtggacaat gctgaagctt agacagaagc
      481 tgcggagccc cacaggcacc tctgcaagcc agctgcccag gagcaagcgg agggccatgg
      541 aggcaaggat atgctcagag gttttaactc tactcagcaa cctggctgac ctggcaaatg
      601 ctgtgcactg gttgccccga ggtgtcctgt gggctggccg cttccctcct tggctggtgg
      661 gtctcatggg caccatctcc tccatcctca gcacatgcca agctgtcagg gctggcagac
      721 aggccgaggc agacagccct tgatgaggcc ctgaagtggc aggtggagga cactgtggtg
      781 ctcaacagga ctcagattcc cagagtggga atcactggcc actggtgcat ccataagtgt
      841 gtactccggt gctggcccct gggcagggtg ggaaaggggc tgaaatgaga tcttctcagg
      901 ccccagccag ggtttcaggg gaagctgctt tcttgggaag aggggggcac atgagaactt
      961 caggactctc agagccaagg gcaaggtttg caaagtccca ggaggacact gctagagcct
     1021 cctacctgct ggcttgccta aaggtgagtg ggagagacac atgcctcagg tcgggcttcg
     1081 gcaaagctgg aatataggaa tgtctattaa aatctcttgg tatggtgcca gtgtgtgcat
     1141 gaggtgatta gagcagtctc actctggcct tccctcctct gggcctatgt cacaaggttt
     1201 gctctcacaa gtgcactgaa cacgagtggg aaaccactca tctctgttct accccccagc
     1261 ctactggcct cagaatctga ctgacctctg cccactgagc ccaggactag gatcacgctc
     1321 tgcacttcct gtggttctca gagggaaact gttggtcact gcctccagga aggccaccct
     1381 taaatgaggg acctcaaggg ctgcagtgtt cccatttaag ctggggccag gccatggttg
     1441 tcggcctctc tgaagatgtg tagatggatt tgtgtcctct atcaaagaga ccatggtaga
     1501 ttgtgccttt tcttcttaag cagtttgagt gtttattaca tttgtgtgtg tgtgtgtgca
     1561 cgtgtgtgtc acggctctca ccatccacgt cctagagatt gagcttggtt tgttaggctt
     1621 ggctgcaggc gccagtactc atggggcctt cacctgttca catgcatcgt ttttgatctg
     1681 aaagctaagc atgtctgcga gactctgagc ccagcctagg agacagtggc ccttgaactt
     1741 tatatgatcc aaccttttgt gtttgtcttg agacagtcct gctgcacagg caaggctcct
     1801 tcctaagtac agcaatgtct tttctttccc tttctccccc tccctactag ggatggatga
     1861 cttgtgtgct ctactgtcaa gatacaatgc cctctggccc tctccccttc tggtgttggc
     1921 caaagtccaa gaaacttttt tttttttttt ttaaatgtgg aagataggtg tttgtgggcc
     1981 accgggatgc tggacccact ggggtggagg gttagaggac cccagcaaag cattccaccc
     2041 ttttgcttat gggcacctgt gcagagctca tgagtaggcc aggatcagct cctatctctg
     2101 gtggtcccac ctgctcgaac tcttaagacc atcaggtagg agtcctggta tctgttcccc
     2161 acctaaagac tgagcccatg aggctctcag atgagtgcct tacctagtca gggtgccagg
     2221 aagacaggct gagcttgagg tccaagcctt gcacaggaag actttgacat gaacagtgta
     2281 tggtgcagac atggaaccaa aggacagata cttctagaaa aggcagccca cccgagctgt
     2341 gcagtggttc taagatctca tgtgtaccag ccaagtcctc catcagttga gctccagtcc
     2401 ccattacagc ttatttttct gtgtttgaga caaggtctta tttggttagg ttgccttgaa
     2461 tttactatgt agtcaaggac gcgtgaaact tctttttgag acatggtctc cctatgtact
     2521 ccctatgtag cctcggctgg cctcaaactc atagaggtct gtctgcctct gcctcctgag
     2581 tggtggcatt aaaggtgtgt gccgccatac ccaactaaac ttttattttt cagaaaaaga
     2641 cttacttgtg tatgtacctc acgcatgcct ggtgcctatg gaggttgggt cccctagaac
     2701 tggagttaac atgatttgga gccaccatgg gagacaaacc caggccatgt caaagagtac
     2761 ccagtgctct tcaacactga accaccacat ctccagcccc cagaccttaa acataaaata
     2821 aaaaagtaaa taactaaa
//
