LOCUS       NM_152799               4466 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus platelet endothelial aggregation receptor 1 (Pear1),
            transcript variant 2, mRNA.
ACCESSION   NM_152799
VERSION     NM_152799.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4466)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4466)
  AUTHORS   Morrison,V., Houpert,M., Trapani,J., Brockman,A., Kingsley,P.,
            Katdare,K., Layden,H., Nguena-Jones,G., Trevisan,A.,
            Maguire-Zeiss,K., Marnett,L., Bix,G., Ihrie,R. and Carter,B.
  TITLE     Jedi-1/MEGF12-mediated phagocytosis controls the pro-neurogenic
            properties of microglia in the ventricular-subventricular zone
  JOURNAL   Cell Rep 42 (11), 113423 (2023)
   PUBMED   37952151
  REMARK    GeneRIF: Jedi-1/MEGF12-mediated phagocytosis controls the
            pro-neurogenic properties of microglia in the
            ventricular-subventricular zone.
REFERENCE   3  (bases 1 to 4466)
  AUTHORS   Elenbaas,J.S., Pudupakkam,U., Ashworth,K.J., Kang,C.J., Patel,V.,
            Santana,K., Jung,I.H., Lee,P.C., Burks,K.H., Amrute,J.M.,
            Mecham,R.P., Halabi,C.M., Alisio,A., Di Paola,J. and Stitziel,N.O.
  TITLE     SVEP1 is an endogenous ligand for the orphan receptor PEAR1
  JOURNAL   Nat Commun 14 (1), 850 (2023)
   PUBMED   36792666
  REMARK    GeneRIF: SVEP1 is an endogenous ligand for the orphan receptor
            PEAR1.
            Erratum:[Nat Commun. 2023 Mar 17;14(1):1511. doi:
            10.1038/s41467-023-37005-x.. PMID: 36932061]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4466)
  AUTHORS   Geng,Y., Li,L., Yan,J., Liu,K., Yang,A., Zhang,L., Shen,Y., Gao,H.,
            Wu,X., Noth,I., Huang,Y., Liu,J. and Fan,X.
  TITLE     PEAR1 regulates expansion of activated fibroblasts and deposition
            of extracellular matrix in pulmonary fibrosis
  JOURNAL   Nat Commun 13 (1), 7114 (2022)
   PUBMED   36402779
  REMARK    Erratum:[Nat Commun. 2022 Dec 14;13(1):7749. doi:
            10.1038/s41467-022-35543-4.. PMID: 36517493]
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4466)
  AUTHORS   Trevisan,A.J., Bauer,M.B., Brindley,R.L., Currie,K.P.M. and
            Carter,B.D.
  TITLE     Jedi-1 deficiency increases sensory neuron excitability through a
            non-cell autonomous mechanism
  JOURNAL   Sci Rep 10 (1), 1300 (2020)
   PUBMED   31992767
  REMARK    GeneRIF: These results provide new insight into the expression
            pattern of Jedi-1 in the peripheral nervous system and indicate
            that loss of Jedi-1 alters DRG neuron activity indirectly through
            an intercellular interaction between non-neuronal cells and sensory
            neurons.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4466)
  AUTHORS   Sullivan,C.S., Scheib,J.L., Ma,Z., Dang,R.P., Schafer,J.M.,
            Hickman,F.E., Brodsky,F.M., Ravichandran,K.S. and Carter,B.D.
  TITLE     The adaptor protein GULP promotes Jedi-1-mediated phagocytosis
            through a clathrin-dependent mechanism
  JOURNAL   Mol Biol Cell 25 (12), 1925-1936 (2014)
   PUBMED   24743597
  REMARK    GeneRIF: Jedi-1 signals through recruitment of GULP, which promotes
            phagocytosis through a noncanonical phosphoclathrin-dependent
            mechanism.
REFERENCE   7  (bases 1 to 4466)
  AUTHORS   Scheib,J.L., Sullivan,C.S. and Carter,B.D.
  TITLE     Jedi-1 and MEGF10 signal engulfment of apoptotic neurons through
            the tyrosine kinase Syk
  JOURNAL   J Neurosci 32 (38), 13022-13031 (2012)
   PUBMED   22993420
  REMARK    GeneRIF: These results indicated that both Jedi-1 and MEGF10 can
            mediate phagocytosis independently through the recruitment of Syk.
REFERENCE   8  (bases 1 to 4466)
  AUTHORS   Wu,H.H., Bellmunt,E., Scheib,J.L., Venegas,V., Burkert,C.,
            Reichardt,L.F., Zhou,Z., Farinas,I. and Carter,B.D.
  TITLE     Glial precursors clear sensory neuron corpses during development
            via Jedi-1, an engulfment receptor
  JOURNAL   Nat Neurosci 12 (12), 1534-1541 (2009)
   PUBMED   19915564
  REMARK    GeneRIF: a cellular and molecular mechanism by which neuronal
            corpses are culled during dorsal root ganglia development involves
            Jedi protein
REFERENCE   9  (bases 1 to 4466)
  AUTHORS   Krivtsov,A.V., Rozov,F.N., Zinovyeva,M.V., Hendrikx,P.J., Jiang,Y.,
            Visser,J.W. and Belyavsky,A.V.
  TITLE     Jedi--a novel transmembrane protein expressed in early
            hematopoietic cells
  JOURNAL   J Cell Biochem 101 (3), 767-784 (2007)
   PUBMED   17226770
  REMARK    GeneRIF: Jedi is involved in the fine regulation of the early
            stages of hematopoietic differentiation, presumably through the
            Notch signaling pathway.
REFERENCE   10 (bases 1 to 4466)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Kitamura,H., Nakagawa,T., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB848869.1, BY236825.1, AF440279.1 and AC122439.4.
            
            On Sep 2, 2005 this sequence version replaced NM_152799.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1, 2, 3, and 4 all encode the same isoform
            (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.7457.1,
                                           SRR13422591.256812.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-76                BB848869.1         2-77
            77-360              BY236825.1         68-351
            361-3973            AF440279.1         386-3998
            3974-4466           AC122439.4         110579-111071
FEATURES             Location/Qualifiers
     source          1..4466
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 38.5 cM"
     gene            1..4466
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /note="platelet endothelial aggregation receptor 1"
                     /db_xref="GeneID:73182"
                     /db_xref="MGI:MGI:1920432"
     exon            1..76
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            77..175
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            176..245
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            246..407
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     CDS             313..3417
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /note="isoform a precursor is encoded by transcript
                     variant 2; Jedi; mPEAR1; protein Jedi; jagged and Delta
                     protein; multiple EGF-like domains protein 12; multiple
                     epidermal growth factor-like domains protein 12"
                     /codon_start=1
                     /product="platelet endothelial aggregation receptor 1
                     isoform a precursor"
                     /protein_id="NP_690012.2"
                     /db_xref="CCDS:CCDS38474.1"
                     /db_xref="GeneID:73182"
                     /db_xref="MGI:MGI:1920432"
                     /translation="MPLCPLLLLALGLRLTGTLNSNDPNVCTFWESFTTTTKESHLRP
                     FSLLPAESCHRPWEDPHTCAQPTVVYRTVYRQVVKMDSRPRLQCCRGYYESRGACVPL
                     CAQECVHGRCVAPNQCQCAPGWRGGDCSSECAPGMWGPQCDKFCHCGNNSSCDPKSGT
                     CFCPSGLQPPNCLQPCPAGHYGPACQFDCQCYGASCDPQDGACFCPPGRAGPSCNVPC
                     SQGTDGFFCPRTYPCQNGGVPQGSQGSCSCPPGWMGVICSLPCPEGFHGPNCTQECRC
                     HNGGLCDRFTGQCHCAPGYIGDRCQEECPVGRFGQDCAETCDCAPGARCFPANGACLC
                     EHGFTGDRCTERLCPDGRYGLSCQEPCTCDPEHSLSCHPMHGECSCQPGWAGLHCNES
                     CPQDTHGPGCQEHCLCLHGGLCLADSGLCRCAPGYTGPHCANLCPPDTYGINCSSRCS
                     CENAIACSPIDGTCICKEGWQRGNCSVPCPLGTWGFNCNASCQCAHDGVCSPQTGACT
                     CTPGWHGAHCQLPCPKGQFGEGCASVCDCDHSDGCDPVHGQCRCQAGWMGTRCHLPCP
                     EGFWGANCSNTCTCKNGGTCVSENGNCVCAPGFRGPSCQRPCPPGRYGKRCVQCKCNN
                     NHSSCHPSDGTCSCLAGWTGPDCSEACPPGHWGLKCSQLCQCHHGGTCHPQDGSCICT
                     PGWTGPNCLEGCPPRMFGVNCSQLCQCDLGEMCHPETGACVCPPGHSGADCKMGSQES
                     FTIMPTSPVTHNSLGAVIGIAVLGTLVVALIALFIGYRQWQKGKEHEHLAVAYSTGRL
                     DGSDYVMPDVSPSYSHYYSNPSYHTLSQCSPNPPPPNKVPGSQLFVSSQAPERPSRAH
                     GRENHVTLPADWKHRREPHERGASHLDRSYSCSYSHRNGPGPFCHKGPISEEGLGASV
                     MSLSSENPYATIRDLPSLPGEPRESGYVEMKGPPSVSPPRQSLHLRDRQQRQLQPQRD
                     SGTYEQPSPLSHNEESLGSTPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPSPPSR
                     RQDR"
     exon            408..512
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            513..613
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            614..706
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            707..950
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1071
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1208
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1421
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1596
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1717
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..1881
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            1882..1984
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2131
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            2132..2260
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            2261..2389
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            2390..2518
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            2519..2731
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            2732..2820
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            2821..2944
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            2945..3019
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            3020..3265
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     exon            3266..4466
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4443..4448
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /note="hexamer: AATAAA"
     polyA_site      4461
                     /gene="Pear1"
                     /gene_synonym="3110045G13Rik; Jedi-1; Megf12"
                     /note="major polyA site"
ORIGIN      
        1 agccagctct gtcggccagc aggacccgtc ggtacaacac gccgctctga gctccgagct
       61 ccgagccccg aggcaggtct ctgctgaccc catcttggct tctagccctg agcagggcag
      121 ctgaggactc ctccgcagtg cagccccacc ctgaaggccg tcggaaggag ggcagaatct
      181 agatcttgag cactgggatc cacagaacat cacctggctg cctaggccca tgctggccat
      241 cactgatgtg tccttccggc tgctggctgc agtgctgttt tgttaccgtg tgccctatcg
      301 caggcctctg caatgccact ttgtcccctc ctcctcctgg ccctaggcct gcgtctgact
      361 gggacactca actccaatga tcccaatgtc tgtacctttt gggaaagctt caccacgacc
      421 actaaggagt cccacctgcg ccccttcagc ctgctcccag ctgagtcctg ccacaggccc
      481 tgggaggacc cccacacctg tgcccagcct acggttgtct accggactgt gtaccgtcag
      541 gtggtgaaga tggactcccg cccacgcctg cagtgctgta ggggttacta cgagagcaga
      601 ggggcctgtg tcccactctg tgcccaggag tgtgtccatg gtcgctgtgt ggctccgaat
      661 cagtgccagt gtgcaccagg ctggcggggt ggcgactgct ccagcgagtg tgccccggga
      721 atgtggggac cacagtgtga caagttctgc cactgtggca acaacagttc ctgtgatccc
      781 aagagtggga cgtgcttttg cccctctggc ctgcagcccc ccaactgcct tcagccctgc
      841 cctgccggcc actatggtcc tgcctgccag tttgattgcc agtgctatgg ggcatcctgt
      901 gacccccagg atggagcctg tttctgccct ccagggagag caggacccag ctgtaatgtg
      961 ccctgttcac agggcactga tggcttcttc tgccccagaa cctatccttg ccaaaatgga
     1021 ggtgttcctc agggctccca aggctcctgc agctgcccac cgggctggat gggtgtcatt
     1081 tgttccctgc catgcccaga gggtttccat ggacccaact gtactcagga atgtcgctgc
     1141 cacaacggtg gcctctgtga caggtttact gggcagtgcc actgtgctcc tggctatatc
     1201 ggggatcggt gccaagaaga gtgccccgtg ggccgcttcg gtcaagactg tgctgagacc
     1261 tgtgactgtg ctcctggcgc ccgttgcttt cctgctaatg gcgcgtgtct gtgtgaacat
     1321 ggcttcacag gcgaccgctg cactgagcgc ctctgtccgg atggccgcta tggtctgagc
     1381 tgccaggagc cctgcacctg cgacccagaa cacagtctca gctgccaccc gatgcacggc
     1441 gagtgctcct gccagccagg ttgggcgggc ctccactgca acgagagctg ccctcaggac
     1501 acgcatggcc cgggctgcca ggagcactgc ctctgtctgc acggagggct ctgccttgcc
     1561 gacagcggcc tctgccggtg cgcgccggga tacacgggac ctcactgcgc taacctatgt
     1621 ccaccggaca cttacgggat caactgttcc tcccgctgct cctgtgaaaa tgccattgcc
     1681 tgctctccca tcgacggcac gtgcatctgc aaggaaggtt ggcagcgtgg taactgctct
     1741 gttccctgtc cccttggcac ctggggcttc aattgcaatg ccagttgcca gtgtgcccac
     1801 gacggagtct gcagccccca aactggagcc tgtacttgca cccctgggtg gcatggtgct
     1861 cactgccagc ttccctgccc gaagggacag tttggtgaag gctgtgccag tgtctgtgac
     1921 tgtgaccact ctgatggctg tgaccctgtt catggacagt gccgatgtca ggctggttgg
     1981 atgggcacac gctgccacct gccttgcccg gagggctttt ggggagccaa ctgcagtaac
     2041 acctgtacct gcaagaatgg tggtacctgt gtgtctgaga atggcaactg cgtgtgcgca
     2101 ccagggttcc gaggcccctc ctgccagagg ccctgcccgc ctggtcgcta tggcaaacgc
     2161 tgtgtgcaat gcaagtgtaa caacaaccat tcttcctgcc acccatcgga cgggacctgc
     2221 tcctgcctgg cgggctggac aggccctgac tgctccgagg catgtccccc aggccactgg
     2281 ggactcaaat gctcccaact ctgccagtgt catcatggtg ggacctgcca cccccaggat
     2341 gggagctgta tctgcacgcc aggctggact ggacccaact gcttggaagg ctgcccacca
     2401 agaatgtttg gtgtcaactg ctcccagcta tgtcagtgtg atctcggaga gatgtgccac
     2461 ccagagactg gggcttgtgt ctgtccccca ggacacagtg gtgcagactg caaaatggga
     2521 agccaggagt ccttcaccat aatgcccacc tctcccgtga cccataactc actgggtgca
     2581 gtgattggca ttgcagtact gggaaccctc gtggtggccc tgatagcact gttcattggc
     2641 taccgccagt ggcaaaaggg caaggaacat gagcacttgg cagtggctta cagcactggg
     2701 cggctggatg gctctgatta cgtcatgcca gatgtctctc cgagctatag tcactactac
     2761 tccaacccca gctaccacac actgtctcag tgttctccta accccccacc ccctaacaag
     2821 gtcccaggca gtcagctctt tgtcagctcc caggcccctg agcggccaag cagagcccac
     2881 gggcgtgaga accatgtcac actgcccgct gactggaagc accgccggga gccccatgaa
     2941 agaggcgcca gccacctgga ccgaagctat agctgtagct atagccacag gaatggcccg
     3001 ggaccattct gtcataaagg tcccatctct gaagagggac taggggcaag cgttatgtcc
     3061 ctgagcagtg agaaccccta tgctaccatc cgagacctgc ccagcctgcc tggggaaccc
     3121 cgagaaagcg gctatgtgga gatgaaagga cctccatcag tgtcccctcc caggcagtct
     3181 cttcatctcc gggacaggca gcagcggcaa ctgcagccac agagggacag tggcacctat
     3241 gagcagccca gccccttgag ccataatgaa gagtctttgg gctccacgcc cccgcttcct
     3301 ccaggcctgc ctcctggtca ctacgactcc cccaagaaca gccatatccc tggacactat
     3361 gacttgcctc cagtacggca tcctccatcc cctccatccc ggcgccagga ccgctgaaga
     3421 gccggcatgg tatgggagcg tgcctatgta ccctgccagg agcagggact ggaccagcag
     3481 gccacgaaca gaaacacttg gtgaagtgaa cagagacgga ctgtggccct gtgcttccac
     3541 cgagggagac actagttgac aaagtgtcta accctctttt cccacccact gctcaagtcc
     3601 ctgtggacat aagctggtgg gcagaatgtt gttgtacaag tgtgatttta gatcgatttt
     3661 ttttaaaagt atgtgttggg taccttttct gtgtgtatgc tcaggcaggc tgtgtgtgtc
     3721 tctagttggc tttagaggga gtcaggtata ggttctgcct tctgcacttt ccatcttatc
     3781 tagtagtcag cttccaagct taactagtta gagctccacc agcagcaggc cctaactacc
     3841 tgcctgccct tcacccagta atcctccatg tctttgctca gaggattgct ccccgactct
     3901 ggtgtttgtc ctcctggtac gccttgacgg tcctgcagtc tccctttccc gtctcgcttc
     3961 attctttccc agaatgaagg ctgtctgcca ccctacttcc cagcccagga attggcacat
     4021 ctaagttcag ccttcctaag ttacccgttg agtcctgctt gcccttcaca tattccacag
     4081 aacacccacc ccacatctgc ttcatagcta ctctcttctc cacgtaccca cagaaggcag
     4141 aagtggtacc aggcaagaag atgggattgt tgcattttgt tttgtttttg agactctgtc
     4201 tcactatgta gtcctggctg gcctggaact caagagctct gcttgcctct gcctcttgag
     4261 tgctgggttt aacggctcag ggtcacatgc acagctcaag ctgcactccg atgtgctttc
     4321 ccctgttgct agattagcgt ctgcctcccc ctagtggaga ggctgatcgc cagctctctg
     4381 atgcaggact ctggtgttta ggctcactca ctattggttt ccttggcaca gggtagtcac
     4441 tcaataaatg ttcctctaaa agctga
//
