LOCUS       NM_001164593            3956 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus PDZ domain containing RING finger 4 (Pdzrn4),
            transcript variant 1, mRNA.
ACCESSION   NM_001164593 XM_001481302 XM_992218
VERSION     NM_001164593.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3956)
  AUTHORS   Son EJ, Wu L, Yoon H, Kim S, Choi JY and Bok J.
  TITLE     Developmental gene expression profiling along the tonotopic axis of
            the mouse cochlea
  JOURNAL   PLoS One 7 (7), e40735 (2012)
   PUBMED   22808246
REFERENCE   2  (bases 1 to 3956)
  AUTHORS   Caqueret A, Boucher F and Michaud JL.
  TITLE     Laminar organization of the early developing anterior hypothalamus
  JOURNAL   Dev Biol 298 (1), 95-106 (2006)
   PUBMED   16860307
REFERENCE   3  (bases 1 to 3956)
  AUTHORS   Okazaki N, F-Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S,
            Saga Y, Seino S, Nishimura M, Kaisho T, Hoshino K, Kitamura H,
            Nagase T, Ohara O and Koga H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY708733.1, BC151034.1, AK135524.1 and AK003741.1.
            
            On or before Sep 9, 2009 this sequence version replaced
            XM_001481302.1, XM_992218.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC151034.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-71                BY708733.1         1-71
            72-1172             BC151034.1         1-1101
            1173-1173           AK135524.1         593-593
            1174-3173           BC151034.1         1103-3102
            3174-3288           AK003741.1         1-115
            3289-3956           AK003741.1         119-786
FEATURES             Location/Qualifiers
     source          1..3956
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 46.53 cM"
     gene            1..3956
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /note="PDZ domain containing RING finger 4"
                     /db_xref="GeneID:239618"
                     /db_xref="MGI:MGI:3056996"
     exon            1..696
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..3150
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="PDZ domain-containing RING finger protein 4
                     isoform 1"
                     /protein_id="NP_001158065.1"
                     /db_xref="CCDS:CCDS49709.1"
                     /db_xref="GeneID:239618"
                     /db_xref="MGI:MGI:3056996"
                     /translation="MGFALERLAEAVDPAFQCQLLCGQVLEEPACTPCGHVFCASCLL
                     PWAAGRRWCPLQCQPLAPGELYRVLPLRSLVQQLRVQCNYSGQGCGHRGDCGCWQCTS
                     SAAPSALPAAVTATAQAAAEAAGRKSTRRPRPAGVGTRVRGHPDLEVGLWLSPAVGVG
                     KTRRAQVSLLQRRYQEKLALYMAHTRNFVGNPGGRGQDGEQKPFTVVLEREDDTLGFN
                     IIGGRPYQNSQKQSAPEGIYVSKILENGPADRADGLEVHDKIIAVNGRDLSKATHEEA
                     VEAFRTAKEPIVVQVLRRTPLSRPTYGMTPEVQLTNASTQTDITFEHIMALAKLRPLT
                     PPVPDTCPFLLSDSCHSLHPMEHGFYEDHEYVSSLPADADRADDFEYEEVELCRVSSQ
                     EKLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQINGEDIQNREEAVA
                     LLSSDECKRIVLLIARPDMQLDEGWLEDERNEFLEELNSELLEEDHNEGAQRTASELQ
                     QPKKQEEEEGTTDTATSSSNNQEKDSGVGRTDESLRNDESSEQENAVEEPHSTTLKSK
                     RELGKSQDTLGSLEHQCSESCAGGECLDSDCASNQEVCEGFQQLLELKIRNHGDYDLY
                     YSSSTIECNRGEQDGVEHELQLLNEELRNIELECQNIMQAHRLQKVTDQYGDIWALHD
                     GGFRNYNTSLDVQRGKLDDIMEHPEKSDKDSSSAYNTAESCRSTPLTVDRSPDSSLPR
                     MINLTNKKNLRSMMTAHQSPPRQSTREYTSTKVKATDEGCSVESLEKGLESSQLLDQE
                     HTVSEHPPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSAVEYAQSQLSLVSMCKE
                     SQRGSEPKMEWKVKIRSDGTRYITKRPVRDRLLKERALKIKEERSGMTTDDDTMSEMK
                     MGRYWSKEERKQHLVRAKEQRRRREFMMRSRLESLKESPQSSGEGKKELSIIELSHKK
                     MMKKRNKKILDNWMTIQELMTHGAKSPDGTRVHNAFLSVTTV"
     exon            697..783
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /inference="alignment:Splign:2.1.0"
     exon            784..891
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1148
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /inference="alignment:Splign:2.1.0"
     exon            1149..1251
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1350
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1413
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /inference="alignment:Splign:2.1.0"
     exon            1414..1515
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /inference="alignment:Splign:2.1.0"
     exon            1516..1632
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..3956
                     /gene="Pdzrn4"
                     /gene_synonym="1110017D07Rik; LNX4; mKIAA3027; SAMCAP3L"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaagagctca gcagcggtaa gaccgctggc cctggcgcag cttgggggtg attgaaagaa
       61 gaagcgggga cacccctttt ggctctcctc cctcccacca ctagcatggg cttcgctttg
      121 gagcgtctcg cggaagccgt ggaccccgct ttccagtgcc agctactgtg tggccaggta
      181 ctggaggagc ccgcgtgcac gccttgcggg cacgtcttct gcgccagctg cctgctgccc
      241 tgggcggcgg ggagacgctg gtgcccgctg cagtgccagc cgctggcgcc gggcgagctg
      301 taccgggtgc tgccgctgcg cagcctggtc cagcaactgc gcgtgcagtg caactacagc
      361 ggacagggct gtggccacag gggcgactgc gggtgctggc agtgcacatc cagcgctgcg
      421 ccttcggccc tgccagcggc tgtgacagcc actgcccagg cggctgcgga ggcggcgggg
      481 aggaaaagca cccggcgacc aagacctgct ggagtgggga cgcgcgtgag gggccacccg
      541 gacctggagg tcggcctctg gttgtcgcct gctgtcgggg tggggaagac gcggcgggcg
      601 caggtcagct tgttgcagcg caggtatcag gagaagttgg ctctgtacat ggcgcacacg
      661 cgcaacttcg tcgggaaccc gggaggccgc ggccaggatg gagagcagaa gccgttcact
      721 gttgtgttgg aaagagaaga tgacactttg ggattcaaca taataggagg ccgcccatat
      781 cagaattccc agaagcaatc agcgcctgaa ggaatttatg tctcaaaaat tttagaaaac
      841 ggacctgcag accgagcaga tggcctggag gttcatgaca aaatcattgc ggtcaatggc
      901 agggatctct caaaggccac tcatgaagag gcagtggaag cttttcgaac tgccaaggag
      961 cccatagtgg tacaggtgtt aaggcggact cccctcagcc ggccaacata cggcatgact
     1021 ccggaagtac agctcacgaa tgccagcaca cagacggaca tcacttttga acacatcatg
     1081 gccctggcga agcttcggcc actcacccct ccggtgcctg acacctgtcc atttttgctt
     1141 tcagacagct gccactccct tcatccgatg gagcatgggt tttatgaaga ccatgagtac
     1201 gtctccagct tgcccgctga tgcagacaga gcagatgact ttgaatatga ggaggtcgag
     1261 ctgtgtcgtg ttagcagtca agagaagctg ggcctgacag tctgctaccg aaccgatgat
     1321 gaagaagaca cgggcattta tgtcagcgag gttgacccaa atagcattgc tgccaaggat
     1381 ggccggattc gagaagggga tcgtatttta caaataaatg gggaagacat ccaaaaccgg
     1441 gaagaggccg tggctctgct ctccagcgat gagtgtaaga gaatcgtgct gctcatcgcc
     1501 aggcccgaca tgcagctgga tgaaggctgg ctggaagatg aaaggaacga attcttagag
     1561 gagttaaact cagagctgct ggaggaagac cataatgaag gagcacagcg cacagcctct
     1621 gagctgcagc agccaaaaaa acaggaggaa gaagaaggca caacagacac ggccacctcc
     1681 tcttccaaca accaggagaa ggacagtggc gtggggcgca cggatgagag cttgcggaat
     1741 gatgagagct cagagcagga gaacgcagtg gaggagcccc acagcaccac cctgaagagc
     1801 aagagagagc tggggaagag ccaagacacg ctagggagcc ttgagcatca atgcagtgag
     1861 agttgtgctg ggggtgagtg cttagactcc gactgtgcca gcaaccagga ggtgtgtgaa
     1921 ggcttccagc agctgttgga gcttaagatt cgaaaccacg gagattacga cctgtactac
     1981 tcaagcagta ccatcgagtg caatcgaggg gaacaggatg gggtggagca cgagctgcag
     2041 ctgcttaacg aggagctgcg aaacattgag ctagagtgcc agaacatcat gcaggcccac
     2101 aggctccaga aagtgacgga ccaatacgga gacatctggg cattgcatga tgggggattc
     2161 cgaaattaca acaccagcct ggatgtgcaa cgggggaaac tggatgacat catggaacac
     2221 ccagaaaagt cagacaagga cagctcgagt gcgtacaata cggcagagag ctgcagaagc
     2281 actccgctga ctgtagacag gtccccggac agttcccttc caagaatgat caacctcacc
     2341 aataagaaaa atctgagaag catgatgaca gcccatcagt cccctcccag acagagcacc
     2401 agggaataca catctaccaa agtcaaagcc accgatgaag gttgcagcgt cgaaagcctg
     2461 gagaagggtc tagaaagcag ccagcttctg gaccaggagc acacagtcag tgagcatcct
     2521 ccatacctct ctccttatca cagctcctcc tacagatatg ccaacattcc ggcgcatgcc
     2581 cggcattatc aaagctacat gcagttaatt caacagaaat cggctgtgga gtatgcccag
     2641 agtcagctca gcttggtgag catgtgcaag gaatcacaaa ggggctcgga gcccaagatg
     2701 gaatggaagg taaaaattag gagtgatggg acccggtaca tcaccaagag gccagtgaga
     2761 gaccgacttc tgaaggaacg tgccttaaag atcaaggagg agcggagtgg catgaccaca
     2821 gacgacgaca ccatgagtga gatgaaaatg gggcgctact ggagcaagga ggagagaaag
     2881 caacacctgg tccgggccaa ggagcaaagg cggcgccggg agttcatgat gcggagtcgg
     2941 ctggagagcc tcaaagagag cccacagagc agcggcgaag gcaagaagga gctgagcatc
     3001 atcgaactga gccacaaaaa gatgatgaaa aaaagaaaca agaaaatttt ggataactgg
     3061 atgacaatcc aagaactgat gactcatggg gccaaatccc cagatggcac tagggtccat
     3121 aatgcctttc tgtcggtgac caccgtatga ccagacacat ggggacaact ggcttagaga
     3181 gcacgctacc agtttcggta gagtatcatt gcctcgttca atgtggcatt tttatatata
     3241 ttttgtgact ttacagttca aattttttgt aagcaaaaaa aaaaaaaata cctggtactt
     3301 tttaatttgt ttttcatagg ctggtacctt ctttggctaa tatctttcct taacttgtga
     3361 tatattcata gcacacattt atagaaaaaa aaagaaaaca atgaaaaaac aaaaggaaag
     3421 aaaaaatgaa caaaaaaact aaggacctaa ttaattccct attttaatgt atctattgta
     3481 agttaaaaat ctggatttat ttctctaatt ttcttatttc ctattttaat agttcaatgc
     3541 caaaacatgt ctatgcttta cctcctggca cagtgtatgc taaatcagat ctactactaa
     3601 accacatgcc gtatcttgtc ttatacatga agcagcaccc cttgaacatc ttcctgtaca
     3661 tttaacacat aaatggcaat tgtctttgtc tcagtaaagt gtgggtggac aatcttcccg
     3721 tgatatgtag tgacactggt catgtagcta gataattgtg gtaatttgtg acaataaaaa
     3781 aaataaataa attattgatt atccttatga aaagttaacc aaggactgtt attttctttg
     3841 cccacggtgg ttaacatgtt tggttgtatg tgtactatta gaagactctt aattgtgaat
     3901 ttataaattg tgcagttttt ctatcacctt tttccttttc caataaagtt gtttcg
//
