LOCUS       NM_027943               2139 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus protein disulfide isomerase-like, testis expressed
            (Pdilt), mRNA.
ACCESSION   NM_027943 XM_133805 XM_913577
VERSION     NM_027943.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2139)
  AUTHORS   Fujihara,Y., Okabe,M. and Ikawa,M.
  TITLE     GPI-anchored protein complex, LY6K/TEX101, is required for sperm
            migration into the oviduct and male fertility in mice
  JOURNAL   Biol Reprod 90 (3), 60 (2014)
   PUBMED   24501175
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2139)
  AUTHORS   Tokuhiro,K., Ikawa,M., Benham,A.M. and Okabe,M.
  TITLE     Protein disulfide isomerase homolog PDILT is required for quality
            control of sperm membrane protein ADAM3 and male fertility
            [corrected]
  JOURNAL   Proc Natl Acad Sci U S A 109 (10), 3850-3855 (2012)
   PUBMED   22357757
  REMARK    GeneRIF: Protein disulfide isomerase homolog PDILT is required for
            quality control of sperm membrane protein ADAM3 and male
            infertility
            Erratum:[Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5905]
REFERENCE   3  (bases 1 to 2139)
  AUTHORS   van Lith,M., Karala,A.R., Bown,D., Gatehouse,J.A., Ruddock,L.W.,
            Saunders,P.T. and Benham,A.M.
  TITLE     A developmentally regulated chaperone complex for the endoplasmic
            reticulum of male haploid germ cells
  JOURNAL   Mol Biol Cell 18 (8), 2795-2804 (2007)
   PUBMED   17507649
REFERENCE   4  (bases 1 to 2139)
  AUTHORS   van Lith,M., Hartigan,N., Hatch,J. and Benham,A.M.
  TITLE     PDILT, a divergent testis-specific protein disulfide isomerase with
            a non-classical SXXC motif that engages in disulfide-dependent
            interactions in the endoplasmic reticulum
  JOURNAL   J Biol Chem 280 (2), 1376-1383 (2005)
   PUBMED   15475357
  REMARK    GeneRIF: The expression of PDILT, in addition to PDI in the testis,
            suggests that PDILT performs a specialized chaperone function in
            testicular cells. [PDILT]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK005692.1.
            
            On or before Jul 12, 2009 this sequence version replaced
            XM_913577.2, XM_133805.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005692.1, SRR5189685.107222.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2139
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 63.9 cM"
     gene            1..2139
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /note="protein disulfide isomerase-like, testis expressed"
                     /db_xref="GeneID:71830"
                     /db_xref="MGI:MGI:1919080"
     exon            1..228
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            229..428
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             236..2002
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /note="protein disulfide-isomerase-like protein of the
                     testis"
                     /codon_start=1
                     /product="protein disulfide-isomerase-like protein of the
                     testis precursor"
                     /protein_id="NP_082219.1"
                     /db_xref="CCDS:CCDS52378.1"
                     /db_xref="GeneID:71830"
                     /db_xref="MGI:MGI:1919080"
                     /translation="MELLWTPLLLVAACLSEVLGSPEIDTGINISQPLHILEDHNLMV
                     LTPAGLTQTLNETRFLMVIFHNPSLKQSRKLAKELGKAAEIFGKGKNGLGFGKVDITK
                     ETELQQEFDITHAPELKLFFEGNRLKPISCKDVVESTALVVWLRRQISKKALLFNNSD
                     EVADFVKSRPLVIVGFFQDLEEEVAELFYDTIKDFPELTFGAIQIKNSFGRFHVILDS
                     VLVFKKGKIVKRQELINDSTNKDHLNQVIKQQLTGFVIELNPENKDLIYELNILNHML
                     LFISKSSEPYSTISRHYRQIAKEFQNKILFVLVNADEPKNKRIFEYFQISRVNVPSVQ
                     ILNLSSDGRYKMPTDDINFESLKKFCNSFLSKTAKKHKASEEIPKYWDQGPVKKLVGK
                     NFNVVVLDKEKDVFVMFYAPWSEKCRVLLPLLEELGIKYQNHSTVIIAKIDITANDIQ
                     LANPEQYPFFRLFPTDSQEAVMYKGEHTMKGFCDFLESHVKVRIEEEDELLYIEQNEE
                     EEVLAEPEIQLIEKLPENPLLKIEDTSKQDRPVKESPVLDSIRKPEEPERRKETAERE
                     AAAAQPKEQPKPERKLEVKEEL"
     exon            429..635
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            636..769
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            770..907
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1018
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1144
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1342
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..1463
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1464..1642
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1732
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1733..2139
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2116..2121
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /note="putative"
     polyA_site      2139
                     /gene="Pdilt"
                     /gene_synonym="1700007B13Rik"
                     /note="putative"
ORIGIN      
        1 agaacatagt ttcagaggca gctgtgacct ccatgtgctc aagcaggaac tccctttctg
       61 ctcctgggtt tcttgggctc actcattagc agacaggtcc tgctctcaac acaagaggaa
      121 acttaaagcc ttctcctcag acttctgcac cctccctgat tgccacaggg ctgactgccc
      181 cagctccatg tggcctgaca gccccgaaag taatccagct gcttgcaggc catccatgga
      241 actgctttgg acacctttgc tgctggtggc tgcttgcctc tcagaggtcc ttggctcacc
      301 agagatagac acgggcatca acatttccca gcctttgcac atcctggagg atcataactt
      361 aatggtgctg actcccgcag gcttgacgca gacgctgaat gaaacccgct tcctaatggt
      421 gattttccac aacccatcct taaaacagtc caggaagctg gccaaggagc tgggcaaagc
      481 cgcagagatc ttcgggaagg gcaagaatgg cttgggcttt ggcaaagtgg acatcaccaa
      541 ggagacggaa cttcagcagg agtttgacat cacccatgcc ccggaattga agctgttctt
      601 tgagggcaac aggttaaagc ccatcagctg caaagatgtg gttgaatcaa cagctttggt
      661 tgtttggttg agaagacaaa ttagcaagaa agcacttttg ttcaacaaca gcgatgaagt
      721 ggccgatttt gtgaaatcca ggcccttggt catcgttggc ttcttccagg atttagagga
      781 agaagtggca gaattattct atgacaccat caaggacttc ccagaactaa cgtttggagc
      841 gatacaaata aaaaattctt tcgggcgatt ccatgtgatc cttgacagtg tcctggtgtt
      901 taaaaaggga aaaatcgtga aacgtcaaga gcttattaat gacagtacaa acaaagacca
      961 tctcaatcaa gtcataaagc aacagctcac aggctttgtg attgagttaa accctgagaa
     1021 taaggacctg atttatgagc tgaacatctt gaaccacatg ctgctcttta tctccaaaag
     1081 ctcagagccg tacagcacca taagccggca ttacagacaa attgcaaagg aattccagaa
     1141 caagattctt ttcgtcctgg tgaatgcgga tgaacctaaa aacaaacgca tctttgagta
     1201 cttccagatc tcaagagtca atgtcccatc tgttcaaatc ctgaacttaa gctctgacgg
     1261 caggtacaaa atgcccaccg acgacataaa ctttgaaagc ctcaaaaagt tctgcaacag
     1321 cttcctcagc aaaactgcca agaaacacaa agccagtgaa gagattccaa aatattggga
     1381 ccaagggcca gtgaagaagc tcgtggggaa gaacttcaat gtggtcgtcc ttgataagga
     1441 aaaggacgtg tttgtgatgt tctatgctcc ctggtctgag aaatgcaggg tgctgttacc
     1501 actgctggaa gagttgggca taaagtatca aaaccactcc acagtcatca ttgctaagat
     1561 tgacataacg gcaaatgaca ttcagctggc aaacccagaa cagtacccat tcttcaggct
     1621 tttccctact gactcacaag aggctgtcat gtataaagga gaacacacca tgaagggctt
     1681 ttgtgacttc ctggaaagcc atgtcaaggt taggattgag gaagaagatg agctattgta
     1741 cattgagcaa aatgaagagg aggaggtgtt agctgagcca gagattcagc tcatagagaa
     1801 gttgcctgag aatccactgc tcaaaataga ggacacaagc aaacaagaca ggccagtgaa
     1861 agagtctcct gtgctggaca gtataagaaa gccagaagag ccggagagaa ggaaggaaac
     1921 agctgagagg gaggcggcgg cagctcagcc gaaggaacag ccaaaaccag agagaaaact
     1981 ggaagtcaaa gaagaacttt agcttctccg aagccaggga gcaaggatcc cagttccagg
     2041 tcctgacatc agtttctgag tggatctact ctaacaatgc catatatcga atggtagagt
     2101 gggtgggggt tagacaataa agccttgtga gtgtctttc
//
