LOCUS       NM_001163794            4639 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus PDLIM1 interacting kinase 1 like (Pdik1l), transcript
            variant 2, mRNA.
ACCESSION   NM_001163794
VERSION     NM_001163794.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4639)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4639)
  AUTHORS   Timmermans,S. and Libert,C.
  TITLE     Overview of inactivating mutations in the protein-coding genome of
            the mouse reference strain C57BL/6J
  JOURNAL   JCI Insight 3 (13), 121758 (2018)
   PUBMED   29997285
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4639)
  AUTHORS   Goyal,P., Behring,A., Kumar,A. and Siess,W.
  TITLE     Identifying and characterizing a novel protein kinase STK35L1 and
            deciphering its orthologs and close-homologs in vertebrates
  JOURNAL   PLoS One 4 (9), e6981 (2009)
   PUBMED   19756140
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK141823.1, AK139413.1 and BC058514.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660821.110079.1,
                                           SRR1660815.133988.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 AK141823.1         2-5
            5-2850              AK139413.1         2-2847
            2851-4639           BC058514.1         2965-4753
FEATURES             Location/Qualifiers
     source          1..4639
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 66.53 cM"
     gene            1..4639
                     /gene="Pdik1l"
                     /gene_synonym="stk35l2"
                     /note="PDLIM1 interacting kinase 1 like"
                     /db_xref="GeneID:230809"
                     /db_xref="MGI:MGI:2385213"
     exon            1..93
                     /gene="Pdik1l"
                     /gene_synonym="stk35l2"
                     /inference="alignment:Splign:2.1.0"
     exon            94..395
                     /gene="Pdik1l"
                     /gene_synonym="stk35l2"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..1136
                     /gene="Pdik1l"
                     /gene_synonym="stk35l2"
                     /EC_number="2.7.11.1"
                     /codon_start=1
                     /product="serine/threonine-protein kinase PDIK1L"
                     /protein_id="NP_001157266.1"
                     /db_xref="CCDS:CCDS18768.1"
                     /db_xref="GeneID:230809"
                     /db_xref="MGI:MGI:2385213"
                     /translation="MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAP
                     ENVELALREFWALSSIKSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLK
                     GEIAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQI
                     IHRDLKPDNILISQSRMDTSDLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTA
                     CGTDFYMAPEVWEGHYTAKADIFALGIIIWAMLERITFIDTETKKELLGSYVKQGTEI
                     VPVGEALLENPKMELLIPVKKKSMNGRMKQLIKEMLAANPQDRPDAFELELRLVQIAF
                     KDSSWET"
     exon            396..4510
                     /gene="Pdik1l"
                     /gene_synonym="stk35l2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4487..4492
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pdik1l"
                     /gene_synonym="stk35l2"
                     /note="hexamer: AATAAA"
     polyA_site      4510
                     /gene="Pdik1l"
                     /gene_synonym="stk35l2"
                     /note="major polyA site"
ORIGIN      
        1 gactggaggc cgccgcggcc gagggcgcga gctgcgcgat aatggcggcc tgcagagctc
       61 atgagaggga gaagcggcgg cggctgccct gagaaacctc gaccttgaag atggtgagta
      121 gccagccaaa gtacgatcta atacgggagg taggccgagg tagttacggt gttgtgtatg
      181 aagcagtcat cagaaagacc tctgcgagag tagccgtgaa gaaaattcga tgccacgcgc
      241 ctgaaaatgt tgaactagct cttcgagagt tctgggcact aagcagtatc aagagccaac
      301 acccaaatgt gattcacttg gaagagtgca tcctacagaa ggatgggatg gtgcaaaaga
      361 tgtcccacgg ctctaattct tccctttatt tacagcttgt agagacttca ttaaaaggag
      421 aaattgcctt tgatcccaga agcgcctatt atttgtggtt tgtgatggat ttttgtgacg
      481 gaggagatat gaatgagtac ctgttgtcca ggaaacccaa tcgaaagact aacaccagct
      541 tcatgcttca gctcagcagt gctctggcct tcttgcacaa aaaccagata atccaccgag
      601 acctgaagcc tgataacatc ctcatttccc agagcaggat ggacaccagt gacttggaac
      661 ccacactcaa agtggctgat ttcggcctaa gtaaagtttg ctcagcatct gggcagaacc
      721 cagaagaacc tgtcagtgta aacaagtgtt tcctttccac ggcatgcggg acggacttct
      781 acatggctcc cgaagtgtgg gaaggacact acaccgccaa agctgacatt tttgctctgg
      841 gaattatcat ctgggcaatg ctggagagga tcaccttcat agacacggag acaaagaagg
      901 agctcttggg gagttacgta aagcagggga ctgaaattgt gcctgttggg gaggcacttc
      961 tggaaaaccc caaaatggaa cttctcatcc ctgtgaagaa aaagtctatg aatgggcgaa
     1021 tgaaacaact gataaaggaa atgctggccg caaaccctca ggatcgccct gatgcttttg
     1081 aactagaact cagattagtc caaattgcat ttaaagacag cagctgggag acgtgaccta
     1141 ctgcttgcaa gcatcttaga cggtgctgct tcagagtcga tggaaataca tcacatggcc
     1201 gaaaagaaga cggaagttag attccacttt ctaagggttt aggttttatt gtggggtagt
     1261 tttattttct ctctcatttt tcttaatcca tgcaggccat tttattgtat gttttgaatg
     1321 tgtattacca atgtggctgt aaaaaaattt tatttaatga tcattggtaa aaggttggca
     1381 gaaaaaaatt ctcttaggag ccaagcagag aagaaagtcc cattttctag aaatatcttt
     1441 aagtatttta gacattcctt gtcagtatta ggcatttcca tggaagaaga ggtttgcgtg
     1501 ctggtaatgc aaccttcgaa gctttgtaaa ggaaacatat atgtatatat ttatgtatat
     1561 gtcagtatgt gaatgtgtgc attttgcatt ccacatgaag aaaatgccac gtctgtttaa
     1621 attatttgat acaggtttgg gtttttgaga tttgctgatg aaattggtga taaaaaccac
     1681 acaaaccatc cctcatcttc gtccctactc cttctgctac tggaaacata ctaagggtat
     1741 ttttgttgtt gtttttgttg ttttcccagt atacatctct tttttaaagg catcattttg
     1801 gagggtcaga atggctgatg aacgataact gaagctaagc aggtgtaagc cgcagggtgc
     1861 gttagagctc tgcagggcct gtagctcttc caagttgaat cagtcatgga gtctcacggc
     1921 tcgtgcctac cttcaggtgg ctgagcattt gtttgagtaa ttaaaccact gcactgggcc
     1981 atgcgggcac ttgagcatct gctgtaaccc gaggacgtgt tcttctgttc tgaaaacatt
     2041 gcgttacaca actgtaatac ttgattatta attttgagtt ttaagacttt ttctaaatct
     2101 cagcataaag tcgaagaaac caaatgagct caccctggag ttgctggccc tggtgtggct
     2161 tcctgttgga tcactggagt ctctgtcact ttgacagtga tgctgttttc tcttgtcttg
     2221 tgatgcagta atgggactgg taatcactgt cacaaatact ggtcgctctc ttccaaagtg
     2281 agagacgatg caaatggata aaattctatg ccctcaactg cttttcaagt agaaaagttg
     2341 tcgttttcat atggtcacct ggcatctgtc agaaagcaag agactcaact cctgaaggga
     2401 aagtctaact gcatggttgc ctccagattg ttcttgctaa tccaggaaca ttaaggaaag
     2461 gattctttct taaaccagaa caccagtctt taggatgaat tagaagctac cattatatcc
     2521 aggtgaggct ttataaggca ctagctgccc acctccggtg ctggggtaga accttgggcc
     2581 ttaggtgtga gggaagtagc ctaccactaa ccccacgggg atctttttaa gcgttaagat
     2641 gcaaaaggca atagactatc aggatattgc cgttatcagc aactctcctt gtcccctcag
     2701 tgcttgaacc gccataccgt cacattaggt ctggctgtgg ttcagtgaag agcgcttgcc
     2761 tggcatgtac aaggctctgg attcaatccc tgccatcaca aaatcaacag atccattagt
     2821 gtgttcagaa ggtgataaaa gataaacctc acaaaaaaaa tgaaatatgt aaaacgccta
     2881 gactgaatta atctggaagt gtaaaaacgt gaaccgaaag gctttagtta acaaaaaaaa
     2941 tcttatcaaa tgaaaaagtc acatacacat aatatcactt gcagacttag ctaaaagaat
     3001 tctttcagaa ataagaggta gaaatgtcct ggatcttcat ggtaattgac cctgtgggtc
     3061 accaagttga cacagatctg acccgtggat tgagttacaa gaaattagaa aaagtctcat
     3121 tataatggat taccattgac ttggccctca tcagattgat atgtgatgtg tgccaacagt
     3181 tcttggctct acaaatacct gtgcacttga agctgtggtg tcctgagcac atagcttttg
     3241 atcctgcctc cttgaaaata atgagtaatt atcttttgtt ttcgttggtg ctgggatcat
     3301 acccagggcc ttgcttgtgc tacacaaagg tgttagcact gagctaaatg tctagcccca
     3361 gttataattt attttgaaag atttttatct gtgaattaga attctttatt atcggtaagg
     3421 gtgtgaggtg atcaagaaat ttcttccaga acattaagtc cttgtcttct gaaatagctt
     3481 gtgatatcaa caaaaggaca gggatttgtc tttgttcgtt cagtcagggg tatttattaa
     3541 gtacctactg tgtgctcagc acttaagttt agttgatacg acaaccattt aagatttgca
     3601 gttgtagggg ctggagagag gattctacca ttaagaggac ttaatgctct tgcacagaac
     3661 tggaactcag ttcccagcac ccatgttgag tggctcacag ccacctaact ccagctccca
     3721 gggacctaat accctcttgc ttccatgtgc acttgcgcat gcacactcat gcacatacac
     3781 acacacacaa tttaaagaat aaagacaaac cattttttaa aaatggcatt tagtcatgca
     3841 ctttcttcag acgcatataa gacataaaag acgagtgata cttgggaatt ttggataatt
     3901 gctaaaggaa aaaatgcaat caagaaattg tgcacagtgc cttgcccata ataggtactc
     3961 aataaacagt tatccctcat agtctgttgc catggtttct agtgttttat gaaatttgtc
     4021 ttaattgaaa aaaaaaaaga ccaaatattt ccactaaagc ttataggcag ctgtgtccag
     4081 tcactgtagg gttgtacagt tagttcctag gctattaatt tgcacctgtt gtcacttaga
     4141 aacatggggt tctgtagatt cttggtgcta agggatactt tgtcattctg atgaagtaag
     4201 tgttaagtgt cagaaaaata gcacagaata gttctttctg caggtctggg tttttgtttt
     4261 taattgtaaa atgttaccaa tcaaactatt gtagcagcta caaaataatt caccagcatg
     4321 acaaaatagt caaaaaaaaa aaaaaaaaga tgtcatcagc acatcagaaa agaaggcaac
     4381 tttaaaactt ttcttttaaa attgtcaaat atattttatg aagaatttat aaagggggaa
     4441 agtattgtaa tttattgttc atgaggtttt tggttttttt ttttttaata aagtgaattt
     4501 caacaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     4561 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     4621 aaaaaaaaaa aaaaaaaaa
//
