LOCUS       NM_008809               5410 bp    mRNA    linear   ROD 04-MAR-2025
DEFINITION  Mus musculus platelet derived growth factor receptor, beta
            polypeptide (Pdgfrb), transcript variant 2, mRNA.
ACCESSION   NM_008809
VERSION     NM_008809.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5410)
  AUTHORS   Scavuzzo,M.A., Szlachcic,W.J., Hill,M.C., Ziojla,N.M., Teaw,J.,
            Carlson,J.C., Tiessen,J., Chmielowiec,J., Martin,J.F. and
            Borowiak,M.
  TITLE     Pancreatic organogenesis mapped through space and time
  JOURNAL   Exp Mol Med 57 (1), 204-220 (2025)
   PUBMED   39779976
REFERENCE   2  (bases 1 to 5410)
  AUTHORS   Hossain,M.N., Gao,Y., Li,X., Zhao,L., Liu,X., Marie de Avila,J.,
            Zhu,M.J. and Du,M.
  TITLE     Single-cell RNA transcriptomics in mice reveals embryonic origin of
            fibrosis due to maternal obesity
  JOURNAL   EBioMedicine 109, 105421 (2024)
   PUBMED   39476533
  REMARK    Erratum:[EBioMedicine. 2025 Feb;112:105573. doi:
            10.1016/j.ebiom.2025.105573. PMID: 39874704]
REFERENCE   3  (bases 1 to 5410)
  AUTHORS   Wada,T., Takeda,Y., Okekawa,A., Komatsu,G., Iwasa,Y., Onogi,Y.,
            Takasaki,I., Hamashima,T., Sasahara,M., Tsuneki,H. and Sasaoka,T.
  TITLE     Deletion of platelet-derived growth factor receptor beta suppresses
            tumorigenesis in metabolic dysfunction-associated steatohepatitis
            (MASH) mice with diabetes
  JOURNAL   Sci Rep 14 (1), 23829 (2024)
   PUBMED   39394459
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5410)
  AUTHORS   Ma,Q., He,X., Wang,X., Zhao,G., Zhang,Y., Su,C., Wei,M., Zhang,K.,
            Liu,M., Zhu,Y. and He,J.
  TITLE     PTPN14 aggravates neointimal hyperplasia via boosting PDGFRbeta
            signaling in smooth muscle cells
  JOURNAL   Nat Commun 15 (1), 7398 (2024)
   PUBMED   39191789
  REMARK    GeneRIF: PTPN14 aggravates neointimal hyperplasia via boosting
            PDGFRbeta signaling in smooth muscle cells.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5410)
  AUTHORS   Amoedo-Leite,C., Parv,K., Testini,C., Herrera-Hidalgo,C., Xu,F.,
            Giraud,A., Malaquias,M., Fasterius,E., Holl,D., Seignez,C.,
            Goritz,C., Christoffersson,G. and Phillipson,M.
  TITLE     Macrophages upregulate mural cell-like markers and support healing
            of ischemic injury by adopting functions important for vascular
            support
  JOURNAL   Nat Cardiovasc Res 3 (6), 685-700 (2024)
   PUBMED   39196227
REFERENCE   6  (bases 1 to 5410)
  AUTHORS   Justice,M.J., Gilbert,D.J., Kinzler,K.W., Vogelstein,B.,
            Buchberg,A.M., Ceci,J.D., Matsuda,Y., Chapman,V.M., Patriotis,C.,
            Makris,A. et al.
  TITLE     A molecular genetic linkage map of mouse chromosome 18 reveals
            extensive linkage conservation with human chromosomes 5 and 18
  JOURNAL   Genomics 13 (4), 1281-1288 (1992)
   PUBMED   1354644
REFERENCE   7  (bases 1 to 5410)
  AUTHORS   Johnson,K.R. and Davisson,M.T.
  TITLE     A multipoint genetic linkage map of mouse chromosome 18
  JOURNAL   Genomics 13 (4), 1143-1149 (1992)
   PUBMED   1354640
REFERENCE   8  (bases 1 to 5410)
  AUTHORS   Hutchins,J.B. and Jefferson,V.E.
  TITLE     Developmental distribution of platelet-derived growth factor in the
            mouse central nervous system
  JOURNAL   Brain Res Dev Brain Res 67 (2), 121-135 (1992)
   PUBMED   1324805
REFERENCE   9  (bases 1 to 5410)
  AUTHORS   Eccles,M.R.
  TITLE     Genes encoding the platelet-derived growth factor (PDGF) receptor
            and colony-stimulating factor 1 (CSF-1) receptor are physically
            associated in mice as in humans
  JOURNAL   Gene 108 (2), 285-288 (1991)
   PUBMED   1660841
REFERENCE   10 (bases 1 to 5410)
  AUTHORS   Oakey,R.J., Caron,M.G., Lefkowitz,R.J. and Seldin,M.F.
  TITLE     Genomic organization of adrenergic and serotonin receptors in the
            mouse: linkage mapping of sequence-related genes provides a method
            for examining mammalian chromosome evolution
  JOURNAL   Genomics 10 (2), 338-344 (1991)
   PUBMED   1676978
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY753644.1, X04367.1, AK143247.1 and BB291987.1.
            
            On Apr 4, 2009 this sequence version replaced NM_008809.1.
            
            Transcript Variant: This variant (2) contains an alternate in-frame
            splice site, compared to variant 1, that results in an isoform (2)
            that is one amino acid shorter than isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X04367.1, SRR10223970.20038.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-291               BY753644.1         4-294
            292-3016            X04367.1           1-2725
            3017-4570           AK143247.1         2999-4552
            4571-5402           X04367.1           4279-5110
            5403-5410           BB291987.1         268-275
FEATURES             Location/Qualifiers
     source          1..5410
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 34.41 cM"
     gene            1..5410
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /note="platelet derived growth factor receptor, beta
                     polypeptide"
                     /db_xref="GeneID:18596"
                     /db_xref="MGI:MGI:97531"
     exon            1..423
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            424..469
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             430..3726
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /EC_number="2.7.10.1"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2; beta-type platelet-derived growth factor
                     receptor; PDGF-R-beta; CD140 antigen-like family member B;
                     PDGF beta chain; PDGFR-beta; platelet-derived growth
                     factor receptor 1; beta platelet-derived growth factor
                     receptor; platelet-derived growth factor receptor beta"
                     /codon_start=1
                     /product="platelet-derived growth factor receptor beta
                     isoform 2 precursor"
                     /protein_id="NP_032835.2"
                     /db_xref="GeneID:18596"
                     /db_xref="MGI:MGI:97531"
                     /translation="MGLPGVIPALVLRGQLLLSVLWLLGPQTSRGLVITPPGPEFVLN
                     ISSTFVLTCSGSAPVMWEQMSQVPWQEAAMNQDGTFSSVLTLTNVTGGDTGEYFCVYN
                     NSLGPELSERKRIYIFVPDPTMGFLPMDSEDLFIFVTDVTETTIPCRVTDPQLEVTLH
                     EKKVDIPLHVPYDHQRGFTGTFEDKTYICKTTIGDREVDSDTYYVYSLQVSSINVSVN
                     AVQTVVRQGESITIRCIVMGNDVVNFQWTYPRMKSGRLVEPVTDYLFGVPSRIGSILH
                     IPTAELSDSGTYTCNVSVSVNDHGDEKAINISVIENGYVRLLETLGDVEIAELHRSRT
                     LRVVFEAYPMPSVLWLKDNRTLGDSGAGELVLSTRNMSETRYVSELILVRVKVSEAGY
                     YTMRAFHEDDEVQLSFKLQVNVPVRVLELSESHPANGEQTIRCRGRGMPQPNVTWSTC
                     RDLKRCPRKLSPTPLGNSSKEESQLETNVTFWEEDQEYEVVSTLRLRHVDQPLSVRCM
                     LQNSMGGDSQEVTVVPHSLPFKVVVISAILALVVLTVISLIILIMLWQKKPRYEIRWK
                     VIESVSSDGHEYIYVDPVQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHS
                     QATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEY
                     CRYGDLVDYLHRNKHTFLQRHSNKHCPPSAELYSNALPVGFSLPSHLNLTGESDGGYM
                     DMSKDESIDYVPMLDMKGDIKYADIESPSYMAPYDNYVPSAPERTYRATLINDSPVLS
                     YTDLVGFSYQVANGMDFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNY
                     ISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYN
                     AIKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPFSQLVLLLERLLGEGYKKKYQQV
                     DEEFLRSDHPAILRSQARFPGIHSLRSPLDTSSVLYTAVQPNESDNDYIIPLPDPKPD
                     VADEGLPEGSPSLASSTLNEVNTSSTISCDSPLELQEEPQQAEPEAQLEQPQDSGCPG
                     PLAEAEDSFL"
     exon            470..790
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            791..1057
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1185
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1360
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1553
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1554..1669
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1670..1793
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1794..2005
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2006..2100
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2101..2233
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2234..2338
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2339..2449
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2450..2609
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2610..2770
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2771..2889
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2890..3012
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3013..3124
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3125..3224
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3225..3330
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3331..3563
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3564..5410
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5380..5385
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /note="hexamer: ATTAAA"
     polyA_site      5404
                     /gene="Pdgfrb"
                     /gene_synonym="CD140b; Pdgfr; PDGFR-1"
                     /note="major polyA site"
ORIGIN      
        1 ggggcagaga aagcccacag tggtgtgagc tctggggctg tctgtggcca cagtcccggc
       61 taccctatct gggacctagg attgctctgg gagtaacttt gagagagagg agaacagaga
      121 ggaaacagtc cagagccaga gcgggcccag accagtcgtc agtctcctgc ctgccagcta
      181 gacctagggc ggcccctcgg gctgctccgc tcctcccgga ggatgctttt ggagtgagga
      241 ggggccgggc tgcttctcac ccctgagcac cctctccatt cccctgattc tctcagggtt
      301 ttccgcaatc aggccagccc ttctactgct gtccgttttt tgggtccagc aaaataacag
      361 aagacagcga ggtggacttc ctggaggggg tgatagctca catcagaagc catctgtagc
      421 ccggacacca tggggcttcc aggagtgata ccagctttag tcctcagagg ccagttgttg
      481 ctgtccgtgt tatggctcct gggaccgcag acctcccggg gcctagtcat cacgccccct
      541 gggccagagt ttgttctcaa catctccagc acctttgttc tgacctgctc gggctcagct
      601 ccggtgatgt gggaacagat gtcccaggtg ccctggcaag aagcggccat gaatcaggac
      661 ggcaccttct ccagtgtgct gacactgacc aatgtcactg ggggagacac tggggaatac
      721 ttttgtgtct acaacaactc actagggccg gagctcagtg agaggaagcg tatctatatc
      781 tttgtgccag atcccaccat gggcttcctc cctatggact ccgaggacct gttcattttt
      841 gtcacggatg tcactgagac gacaattccg tgccgagtga cagaccccca gctggaggtg
      901 acgctacatg agaagaaagt ggatatcccc ctacacgtac cctacgacca ccagcgaggt
      961 ttcactggta cttttgagga caagacttac atttgcaaaa ccaccattgg ggacagggaa
     1021 gtggactccg atacttacta cgtctacagc ctccaggtgt catccatcaa cgtctctgtg
     1081 aatgccgtgc agactgtggt ccgccagggc gagagcatca ccatccggtg cattgtgatg
     1141 ggcaatgatg tggtgaactt ccaatggacg tacccccgca tgaagagtgg gcggctggtg
     1201 gagccagtga cagactacct ctttggagtg ccctcccgca ttggctccat cctgcatatc
     1261 cccacggctg agctgagtga ttcgggcacc tatacttgca acgtgtcagt gagtgtgaac
     1321 gaccatggcg atgagaaagc catcaacatc tctgtgatcg agaatggcta cgtgcggctg
     1381 ctggagacac tgggagatgt agaaattgct gagctgcacc ggagtcggac gctgcgggtg
     1441 gtgttcgagg cttatccgat gccttctgtc ctgtggctca aggacaaccg taccttgggt
     1501 gactccggcg ctggcgagtt agttttgtct actcgcaaca tgtctgagac ccggtacgtg
     1561 tcagaactga tcctggtacg tgtgaaggtg tcagaagcgg gctactatac tatgcgagcc
     1621 ttccacgagg acgatgaggt ccagctctcc ttcaagctgc aggtcaatgt ccccgtccgt
     1681 gtgctggagc tgagtgagag tcaccctgcc aatggggagc agacaatccg ctgtcgtggc
     1741 cggggcatgc ctcagccaaa tgtcacctgg tctacctgca gagacctcaa aaggtgtcca
     1801 cgaaaactgt cacccacacc cttggggaat agttccaagg aggagagcca gctagaaacg
     1861 aatgtgactt tctgggagga agatcaggaa tacgaggtgg tgagcacact gcgcctgcgc
     1921 cacgtggatc agccactgtc cgtacgctgc atgctgcaga actccatggg tggagattcg
     1981 caggaggtca ccgtggtccc acattccttg cccttcaaag tggtggtgat ctcagccatc
     2041 ctggccttag tggtccttac cgtcatctct ctcatcatcc tcatcatgct gtggcagaag
     2101 aagccacgct atgagatccg atggaaggtc attgagtctg tgagctctga cggtcatgag
     2161 tacatctacg tggaccctgt gcagttgcct tacgactcca cctgggagct gccacgggac
     2221 cagcttgttc tgggacgcac tcttggctct ggggctttcg gacaggtggt ggaggccaca
     2281 gctcacggtc tgagccattc gcaggccacc atgaaagtgg ctgtcaagat gctgaaatcg
     2341 acagccagaa gtagcgagaa gcaagcctta atgtccgagc tgaagattat gagtcatctt
     2401 ggaccccacc tgaacgtggt caacctgctg ggggcctgca ccaaaggagg gcccatctac
     2461 atcatcacgg aatactgccg atacggtgat ctggtggact acctgcaccg gaacaaacac
     2521 accttcttgc agcgacactc caacaagcat tgtccgccca gtgctgagct ctacagcaac
     2581 gccctgccag tggggttctc cctacccagc cacttgaacc tgactgggga gagtgacggt
     2641 ggctacatgg atatgagcaa ggatgaatct atagattacg tgcccatgtt ggacatgaaa
     2701 ggagacatca aatacgcaga cattgagtcc cccagctaca tggcccctta tgataactat
     2761 gtcccatctg cccctgaaag gacctatcgc gccaccttaa tcaacgactc accagtgctc
     2821 agctacacag acctcgtggg cttcagctac caagtggcca acggcatgga cttcttagcc
     2881 tctaagaact gtgttcaccg agacttggcg gccaggaatg tgctcatctg cgagggcaag
     2941 ctggtcaaga tctgtgactt cggcctggct cgagacatca tgagggactc aaactacatc
     3001 tccaaaggca gcaccttcct gcctctgaag tggatggccc cagagagcat cttcaacagc
     3061 ctctacacca ctttgagtga tgtctggtct tttgggatcc tactctggga gatcttcaca
     3121 ctgggtggca ccccttaccc agagctgccc atgaacgacc agttctacaa tgccatcaag
     3181 aggggctacc gcatggccca gcctgctcat gcctccgacg agatctatga gatcatgcag
     3241 aaatgctggg aagaaaagtt tgagactcga ccccccttct cccagctggt gctgctcctg
     3301 gagaggcttc tgggtgaagg ctataaaaag aagtaccagc aggtagatga ggagttcctg
     3361 aggagtgacc atcctgccat cctgaggtcc caagcccgct ttccggggat ccacagcctc
     3421 cgatcccctc tggacaccag ctctgttctc tacactgccg tgcagcccaa tgagagtgac
     3481 aatgactaca tcatcccctt acctgacccc aagcctgacg ttgctgatga aggtctccca
     3541 gaggggtccc ccagccttgc cagttccacc ttgaatgaag tcaacacttc ctccaccatc
     3601 tcctgcgaca gtcccctgga gctccaagaa gagccacagc aagcagagcc tgaggcacaa
     3661 ctggagcagc cacaggattc aggctgccca ggacctctgg ctgaagcaga ggacagcttc
     3721 ctgtaggaac tgacatcact ccattttgcc cgaatctccc ttctgcctcc cagaacccaa
     3781 ccctcttggc ctggcctggc ctggcctggc ctcccagcag ctacactgcc acaagctgtc
     3841 ccctcgagga aagcccttgg tttgcagcac tcaaggtcca gggacccagc ttagcttagg
     3901 aggcaagaga actctgcctc gggaaggtca tgggactctg aaccagggtt cctccagggg
     3961 actcagtttc cccaaatgta agaggaagag ttgtacttgg ctacaggaca ggtctggagc
     4021 ccggattcct gcagaaatcc acgactgtac ggtggtgtgt tcatatcctc ctgtgtagca
     4081 gctgcccctc agctggattg ctctactttg atcttcctaa gaatcaggca aggacctggt
     4141 gtctggctcc tggccaaact gtaaccagcc ttggacaagg tcttttcatt cagagcccac
     4201 ctcccctggt cttagctttc ccaggcccga gctggtctgg ggccagccat gcttaatgaa
     4261 tgctgttagt ggtgaaggta ggccgagtac agaatgctct ggcctgcagc cctgcctggg
     4321 cactcagggc acacctggcc acaggaagca cccactcctt tcagccccac cagtcctaga
     4381 atagtcccca ggtcactctc agctgaccca cccaccagag tctgcagggc cattgtccac
     4441 gcctgtgata ggctaagcat ctgcctgaag tgtgtaccta ccactaggag ccctggctct
     4501 gcgctggacc tgctatgaga ccttgggggc tttccttgtt ctctctgggg accagttttc
     4561 tttccccttt gaaaagcaag ttggacacat agactctgag taccctgtca atagtacaat
     4621 tcttgtatgt tctgggagtt tgctcttgtc ccgaggaagc agggtcaagt ccttaaactg
     4681 atctttctag gggtcagctg agctcttgga agatccctga tacacttcac actctggggg
     4741 ttcaggaacc gagcctcttc ttcaagtctc caagtgcaac tgcccagacc ttgacttgga
     4801 gtgacagtga gtgtcctagg aaaccccctt acagctgtcc tgaggacaca gaagagacca
     4861 cgagaccctt ttttcatatc atgaagccag caagagtggc agagaaggca agccaggtta
     4921 cctcgggcca ctgtcaccag cagcgtgtgg acagacatga tggacagtga ggacagacgt
     4981 cccatgcagg acaagagact tgagatgggc aatgagagga agatgctgac gggattacca
     5041 cctcaactgc cagctgcccc cgtccccagg gagcacccca cagaaacagt tctaaccctg
     5101 aaccaatgaa cattgcaagt gcctggggac tagggagtgg ggggaagtca gcctttctgg
     5161 ggaccctccc tgctagctgg ttggctagct ggcatctccc cgcttggagc agcagaggct
     5221 ggggagtact gctcacaatg gtaccaaaga tagaatcacc taggtttaca agtacttgta
     5281 ggactcgaga taacccacat ttagacaccg gaagtgctat tttatatgct gttaagtttt
     5341 cctatctgta cttttttttt aaatgggaaa gattttaata ttaaacttgg tgcttctcac
     5401 tgaataaccg
//
