LOCUS       NM_016688               2471 bp    mRNA    linear   ROD 20-JUN-2024
DEFINITION  Mus musculus programmed cell death 7 (Pdcd7), mRNA.
ACCESSION   NM_016688 XM_917852
VERSION     NM_016688.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2471)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2471)
  AUTHORS   Olthof,A.M., White,A.K., Mieruszynski,S., Doggett,K., Lee,M.F.,
            Chakroun,A., Abdel Aleem,A.K., Rousseau,J., Magnani,C.,
            Roifman,C.M., Campeau,P.M., Heath,J.K. and Kanadia,R.N.
  TITLE     Disruption of exon-bridging interactions between the minor and
            major spliceosomes results in alternative splicing around minor
            introns
  JOURNAL   Nucleic Acids Res 49 (6), 3524-3545 (2021)
   PUBMED   33660780
REFERENCE   3  (bases 1 to 2471)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (bases 1 to 2471)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   5  (bases 1 to 2471)
  AUTHORS   Park,E.J., Kim,J.H., Seong,R.H., Kim,C.G., Park,S.D. and Hong,S.H.
  TITLE     Characterization of a novel mouse cDNA, ES18, involved in apoptotic
            cell death of T-cells
  JOURNAL   Nucleic Acids Res 27 (6), 1524-1530 (1999)
   PUBMED   10037816
REFERENCE   6  (bases 1 to 2471)
  AUTHORS   Ritzel,M.W., Yao,S.Y., Ng,A.M., Mackey,J.R., Cass,C.E. and
            Young,J.D.
  TITLE     Molecular cloning, functional expression and chromosomal
            localization of a cDNA encoding a human Na+/nucleoside
            cotransporter (hCNT2) selective for purine nucleosides and uridine
  JOURNAL   Mol Membr Biol 15 (4), 203-211 (1998)
   PUBMED   10087507
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC114645.9, BU518553.1, DV656988.1 and BE946822.1.
            
            On May 23, 2007 this sequence version replaced NM_016688.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript from the same
            strain was available for the full length of the gene. The extent of
            this transcript is supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF083929.1, AK155050.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-586               AC114645.9         180981-181566       c
            587-1149            BU518553.1         1-563
            1150-1780           DV656988.1         163-793
            1781-2024           AC114645.9         168422-168665       c
            2025-2471           BE946822.1         1-447               c
FEATURES             Location/Qualifiers
     source          1..2471
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 35.25 cM"
     gene            1..2471
                     /gene="Pdcd7"
                     /gene_synonym="ES18"
                     /note="programmed cell death 7"
                     /db_xref="GeneID:50996"
                     /db_xref="MGI:MGI:1859170"
     exon            1..941
                     /gene="Pdcd7"
                     /gene_synonym="ES18"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..1529
                     /gene="Pdcd7"
                     /gene_synonym="ES18"
                     /codon_start=1
                     /product="programmed cell death protein 7"
                     /protein_id="NP_057897.2"
                     /db_xref="CCDS:CCDS40670.1"
                     /db_xref="GeneID:50996"
                     /db_xref="MGI:MGI:1859170"
                     /translation="MALPPFFAQSRQGPPPPQPPPSAPFGCPPPPLPSPAFPPPLPQR
                     PGPFPGASAPFLQPPLALQPRAPAEASRGGGGGGAFFPVPPPPLPPPPPQCRPFPGPD
                     AVERPRPPPPGPGPPWSPRWAEAPPPPDVLGDAALQRLRDRQWLEAVFGNPRRPGGLR
                     TPRTPAGPSLGEVRARLRSALRLVRRLRSLGQSLREAEADGAAWASLHAQAAPLRAEL
                     AERLQPLAQAAYVGEARRRLERVRRRRLRLRERARDREAEREAEAAQATEREQEIDRW
                     RVKCVQEVEEKKREQELKAAADGVLAEVRKKQSDTKRMVDILRALEKLRKLRKEAAAR
                     KGVCPPASADETFEHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERRRELEKKQ
                     RKEKEKLLLQKREIESKLFGDPDEFPLAHLLQPFRQYYLQAEHSLPALIQIRHDWDQY
                     LVPSDHPKGNSVPQGWVLPPLPSNDIWATAIQLH"
     exon            942..1080
                     /gene="Pdcd7"
                     /gene_synonym="ES18"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1317
                     /gene="Pdcd7"
                     /gene_synonym="ES18"
                     /inference="alignment:Splign:2.1.0"
     exon            1318..1405
                     /gene="Pdcd7"
                     /gene_synonym="ES18"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..2455
                     /gene="Pdcd7"
                     /gene_synonym="ES18"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2426..2431
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pdcd7"
                     /gene_synonym="ES18"
                     /note="hexamer: AATAAA"
     polyA_site      2455
                     /gene="Pdcd7"
                     /gene_synonym="ES18"
                     /note="major polyA site"
ORIGIN      
        1 gtcacttcct cctggaaccc ggataaagaa gttcccagat tactgtcact gctcccaacc
       61 gctgcactac agacatggct ctgccacctt ttttcgccca gagccgtcag ggacctcccc
      121 ctccgcagcc accgccttcc gctccattcg gctgtccgcc cccgccgctg ccctctccgg
      181 ctttcccgcc gccccttccc cagcgacccg gccccttccc gggggcttcc gcccccttcc
      241 tccagcctcc gctggccctg cagccccgcg cgccagccga ggcctcccgc ggcggtggcg
      301 gtggcggcgc cttcttcccg gtgccacccc caccgctgcc gccgccgccg ccgcagtgcc
      361 ggcccttccc ggggcccgac gccgtcgagc gtccacggcc accgcctcca ggtcccgggc
      421 cgccctggag cccgcgctgg gcggaggcgc cgccgccgcc cgacgtgctc ggagacgcgg
      481 ccctgcagcg cctgcgtgat cggcagtggc tggaggcggt gttcgggaac ccccggcggc
      541 ccggtggcct ccggaccccg cgcacacccg ccgggcccag cctgggtgaa gtccgcgcgc
      601 ggttgcgttc cgctttgcgt ttggtgcggc ggctacgcag cttggggcag tccctgcgcg
      661 aggctgaggc cgacggagca gcctgggcct ccctgcacgc tcaggcggcg ccactacgag
      721 cggagctagc ggagcggctg cagccgctgg cccaggccgc ctatgtgggc gaggcgcgac
      781 ggaggctgga gagggtccgg cgccgccggc tgcggcttcg tgagagggcc cgggatcggg
      841 aggctgagcg ggaggcggag gccgcgcagg ccacggaacg ggagcaggag attgaccgct
      901 ggagggtgaa gtgcgtgcag gaagtggagg aaaagaagcg ggagcaggaa ctcaaagcag
      961 ctgctgatgg ggtcttagct gaagtaagga aaaagcaatc agacaccaaa aggatggtgg
     1021 acattctgcg tgctttagag aagctgagga aactgaggaa agaagctgca gcaaggaaag
     1081 gggtctgtcc tcctgcttca gcggatgaga ctttcgagca ccatcttcag cggctgagaa
     1141 agctcattaa aaagcgctct gaactgtatg aagctgaaga gagagccctc cgagttatgc
     1201 tagaaggaga gcaggaggag gagaggagac gagaactgga aaagaaacag agaaaagaga
     1261 aagagaaact tctactacag aaacgggaaa ttgagtccaa gttattcggg gatccagatg
     1321 agttcccact tgctcacctc ctgcagccat tccggcagta ttacctccag gctgagcact
     1381 ccttgcccgc gctcattcag ataaggcatg attgggatca gtacctggta ccatctgatc
     1441 atccgaaagg caactcggtt ccccaaggat gggtccttcc tccgctcccc agcaacgaca
     1501 tctgggcaac ggccattcag ctgcattaag atgctccagg agtgtggtcc agctggcaag
     1561 cactgcagct ctagatatta gagatgcggt tgtctcacgc tctagtcttc tacacaactt
     1621 aactctgtgt ggcattgtcc tagctggaaa gcctttttct tttgttctct gccctaggca
     1681 ggggtacctc tggagccaga ggttcataag gttcttctgg aaaggatcta gatgaactga
     1741 ggttattagc atgggctgta gccttggctc tctaaatctg cctctgtttt gagaggcttg
     1801 gttcaatgtg gcctgctcat ttgttccagg tttgttatat attggtgggt aagaacaggc
     1861 agcacacttg gctactgctt gaaggtgttc actgagtaga gttagcagct actgctcctt
     1921 atcttcccat accacctgcc ctccagctcc caggagcacc tacagtttcc agtttcagtg
     1981 cagtgtggga ggctgctact gaagatgatg gggcagtggc tgccaggatc actgatggct
     2041 tagaactgtt gtcctgtgga gagcttagaa aacttgaaga gttagcagag ccagggtggc
     2101 ttgtgctctg acagacagtg cctgttttcc tcatgaaagt gccagtgcaa gagttgtgag
     2161 ggaactagtt gtgtggggcc tccaagaata gaaacttatt tccctgtggg actgtaatct
     2221 cagtcacatg gtaggggctg gatagctcaa gcttctaaaa acatccatgt cataaaagcc
     2281 gggaaaagag caaatatgaa agataaattt tatttttata ttcattaata agtgctgttg
     2341 tatttggaca tgatcagtca tatgacatgt tatggttttt gttttgcctt attctgggtt
     2401 ttgttattta atttcctaaa agctgaataa ataccatttt tgcttttttg tttgaaaaaa
     2461 aaaaaaaaaa a
//
