LOCUS       NM_001033313            2139 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus PDGFA associated protein 1 (Pdap1), transcript variant
            1, mRNA.
ACCESSION   NM_001033313 XM_886519 XM_917344
VERSION     NM_001033313.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2139)
  AUTHORS   Delgado-Benito,V., Berruezo-Llacuna,M., Altwasser,R., Winkler,W.,
            Sundaravinayagam,D., Balasubramanian,S., Caganova,M., Graf,R.,
            Rahjouei,A., Henke,M.T., Driesner,M., Keller,L., Prigione,A.,
            Janz,M., Akalin,A. and Di Virgilio,M.
  TITLE     PDGFA-associated protein 1 protects mature B lymphocytes from
            stress-induced cell death and promotes antibody gene
            diversification
  JOURNAL   J Exp Med 217 (10) (2020)
   PUBMED   32609329
  REMARK    GeneRIF: PDGFA-associated protein 1 protects mature B lymphocytes
            from stress-induced cell death and promotes antibody gene
            diversification.
REFERENCE   2  (bases 1 to 2139)
  AUTHORS   Saba,L., Bhave,S.V., Grahame,N., Bice,P., Lapadat,R., Belknap,J.,
            Hoffman,P.L. and Tabakoff,B.
  TITLE     Candidate genes and their regulatory elements: alcohol preference
            and tolerance
  JOURNAL   Mamm Genome 17 (6), 669-688 (2006)
   PUBMED   16783646
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC110556.15.
            
            On May 19, 2018 this sequence version replaced NM_001033313.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147170.1, FO716593.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-59                AC110556.15        214116-214174       c
            60-151              AC110556.15        211051-211142       c
            152-259             AC110556.15        209214-209321       c
            260-381             AC110556.15        207008-207129       c
            382-533             AC110556.15        205514-205665       c
            534-2139            AC110556.15        202919-204524       c
FEATURES             Location/Qualifiers
     source          1..2139
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 85.04 cM"
     gene            1..2139
                     /gene="Pdap1"
                     /gene_synonym="HASPP28; PAP; PAP1"
                     /note="PDGFA associated protein 1"
                     /db_xref="GeneID:231887"
                     /db_xref="MGI:MGI:2448536"
     exon            1..59
                     /gene="Pdap1"
                     /gene_synonym="HASPP28; PAP; PAP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             47..592
                     /gene="Pdap1"
                     /gene_synonym="HASPP28; PAP; PAP1"
                     /note="PDGF-associated protein"
                     /codon_start=1
                     /product="28 kDa heat- and acid-stable phosphoprotein"
                     /protein_id="NP_001028485.1"
                     /db_xref="CCDS:CCDS39384.1"
                     /db_xref="GeneID:231887"
                     /db_xref="MGI:MGI:2448536"
                     /translation="MPKGGRKGGHKGRVRQYTSPEEIDAQLQAEKQKANEEDEQEEGG
                     DGASGDPKKEKKSLDSDESEDEDDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLD
                     GPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEE
                     RKAKDDATLSGKRMQSLSLNK"
     exon            60..151
                     /gene="Pdap1"
                     /gene_synonym="HASPP28; PAP; PAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            152..259
                     /gene="Pdap1"
                     /gene_synonym="HASPP28; PAP; PAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            260..381
                     /gene="Pdap1"
                     /gene_synonym="HASPP28; PAP; PAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            382..533
                     /gene="Pdap1"
                     /gene_synonym="HASPP28; PAP; PAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            534..2139
                     /gene="Pdap1"
                     /gene_synonym="HASPP28; PAP; PAP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1236..1241
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pdap1"
                     /gene_synonym="HASPP28; PAP; PAP1"
                     /note="hexamer: ATTAAA"
     polyA_site      1255
                     /gene="Pdap1"
                     /gene_synonym="HASPP28; PAP; PAP1"
                     /note="major polyA site"
ORIGIN      
        1 gtcagttcga ggcgccgccg ccgccgctgc agccgccgga gccgagatgc ctaaaggagg
       61 tagaaaggga ggccacaaag gccgagtgag gcagtatacg agcccggagg agatcgatgc
      121 ccagctacag gctgagaagc agaaggccaa cgaagaagat gaacaagaag aaggtggaga
      181 tggggcttca ggtgacccaa aaaaggaaaa gaaatctcta gactcagatg aaagtgaaga
      241 tgaagatgat gactaccagc aaaagcgaaa aggcgtggag gggctcattg acattgagaa
      301 ccccaaccgc gtggcacaga caactaagaa ggtcacgcaa ctggatctgg acgggccaaa
      361 ggagctttca aggagagaaa gagaagaaat agagaagcaa aaagcaaaag aacgctacat
      421 gaagatgcat ttggctggga agacagagca ggccaaggct gatctcgccc ggctggcaat
      481 catccggaaa cagcgggagg aggcagcaag aaagaaagag gaagaaagga aagcaaaaga
      541 tgacgcaact ttgtcaggaa aacgaatgca gtcgctgtcc ctgaataagt aagctggcct
      601 gtgggaggag atgccgggga actgggccgt gccgccagga cctctgccat gtctcaccca
      661 ccctgtgccc tggcgccgct gcagcagccc ctatggccag gggcccctac ggcctggggc
      721 ctcctcttca tcttggcaca gaaattgttc aggggatgtg ggggggctgg gggaggggca
      781 gctgctatct ttgagacaga aagatgcagg acagcatttc atacgtaacc atttgaatgt
      841 ttctgctgtt tttagaattt ggaaccctgg tttgggaggg ggggtgcctg ggaagtgggg
      901 tgaggagatt ccatttgtcc agtagattgc acgctagcgt gggagggggg gtgccagcag
      961 gcagctgctg tgggaattga tgacaaccag cccagattgt ctgggtgctc actcagaggg
     1021 gctccaggag cctgtgccgt gaaagggcca aggtttgtgc ctggccagtt ccgtccgatg
     1081 aggcctctcc tctctgttct gtccccttcc cacccacctg gtctgggcta gtgcccgttt
     1141 ttaaccctac ccattgatca tttcaagaaa cctctggtta ccatgcgtca cccagacaag
     1201 acatgctcct caaattcaac ttgtatattt ggcagattaa acgacaacat cgtaattcct
     1261 tgtttggcag tttctctatc agctatctct atctttgctc atggcagtac cagcagggtt
     1321 taggcacaca cctacctggg aagacactgt caggcttttg cacaaagtaa ggatcagggc
     1381 ctagatgtcc gtgacgtaat agagacctgg gaggtttctg agggccagtc ctgaacctac
     1441 agcagactgg agcagtgctg agctgcccct gtggtgccct ggcgctgcct gcctggtcat
     1501 atcctagtct tctgctggag gaaggctccc aggactcccc acagcagtcc ttggcactgt
     1561 gacagggagg aagcaggcct gttgctagcc agtgagttac ttgtacattc aggcccagtg
     1621 aaaggctcct gtcctggccc catctgagtg agatactgca actgaatgac attgtccttt
     1681 gtgctttcta agttggaggg acgtaagggt ctggatgtct cagggtcaga tatgggtgtg
     1741 gctgccagag actcaagcat aacttaatgg cagagatgac atttgagtcc atttttagtg
     1801 accactacca catgcctttg ggcttgactc tgattgatgg cctctggaga ggatcctgca
     1861 gctacccaga ttcaaggttg gctccaaaat gaggaaggtg atagcctttt aacaacgccc
     1921 taatgccctg ttgctagctg taggacagag tagtaaaaag gtttgtaaga ggtctgtggg
     1981 tggggttcca acaccaaatt aaagcgtgct gcttggcttg ggtgcagaag ggtgggtgtg
     2041 gcttttgccc acttgaagga gaccatggat gtggtggcct tcagcgtagg gcctgtcaaa
     2101 cctgaggcct aggctgaatt aaagaactaa tgggcactt
//
