LOCUS       NM_001418426            2081 bp    mRNA    linear   ROD 16-FEB-2025
DEFINITION  Mus musculus prenylcysteine oxidase 1 like (Pcyox1l), transcript
            variant 2, mRNA.
ACCESSION   NM_001418426
VERSION     NM_001418426.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2081)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2081)
  AUTHORS   Petenkova,A., Auger,S.A., Lamb,J., Quellier,D., Carter,C., To,O.T.,
            Milosevic,J., Barghout,R., Kugadas,A., Lu,X., Geddes-McAlister,J.,
            Fichorova,R., Sykes,D.B., Distefano,M.D. and Gadjeva,M.
  TITLE     Prenylcysteine oxidase 1 like protein is required for neutrophil
            bactericidal activities
  JOURNAL   Nat Commun 14 (1), 2761 (2023)
   PUBMED   37179332
  REMARK    GeneRIF: Prenylcysteine oxidase 1 like protein is required for
            neutrophil bactericidal activities.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125157.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422601.295436.1,
                                           SRR13422598.811390.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-148               AC125157.4         108926-109073
            149-355             AC125157.4         112849-113055
            356-530             AC125157.4         114197-114371
            531-587             AC125157.4         114556-114612
            588-799             AC125157.4         117063-117274
            800-940             AC125157.4         118063-118203
            941-2081            AC125157.4         118591-119731
FEATURES             Location/Qualifiers
     source          1..2081
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 34.68 cM"
     gene            1..2081
                     /gene="Pcyox1l"
                     /gene_synonym="C630049M13"
                     /note="prenylcysteine oxidase 1 like"
                     /db_xref="GeneID:240334"
                     /db_xref="MGI:MGI:3606062"
     exon            1..148
                     /gene="Pcyox1l"
                     /gene_synonym="C630049M13"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..1605
                     /gene="Pcyox1l"
                     /gene_synonym="C630049M13"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2; prenylcysteine oxidase-like"
                     /codon_start=1
                     /product="prenylcysteine oxidase 1-like isoform 2
                     precursor"
                     /protein_id="NP_001405355.1"
                     /db_xref="GeneID:240334"
                     /db_xref="MGI:MGI:3606062"
                     /translation="MARAAPLLAVLATVLTTAAAGGDAPPGKIAVIGAGIGGSAVAHF
                     LQQHFGPRVQIVVYEKGTVGGRLATISVNKQNYESGAASFHSLSLHMQDFVKLLGLRQ
                     RREVVGRSAIFGGEHFVLEETDWYLLNLFRLWWYYGISFLRLQMWVEEVMEKFMSSEA
                     LCKLRNFPRLKCDGRRIYKYQAHGYAFSGVEELLYSLGEATFVNMTQRSVAESLLQVG
                     VTQRFIDDVVSAVLRASYGQSASMPAFAGAMSLAGAQGNLWSVEGGNKLVCSGLLKLA
                     KATVIHATVTSVTLHSTEGKALYQVAYESDKGNSSDFYDIVVIATPLHLDNSSNNNIT
                     FEGFTPPIEDIQGSFQPTVVSLVHGYLNSSYFGFPDPKLFPFANILTTDFPSFFCTLD
                     NICPVNISASFRRKQPQEAAVWRVQSPKPLFRTELKTLFRSYYSVQTAEWQAHPLYGS
                     RRTLPRFALHDQLFYLNALEWAASSVEVTAVAAKNVALLAYNRWYQDLDKIDQKDLIH
                     KVKTEL"
     exon            149..355
                     /gene="Pcyox1l"
                     /gene_synonym="C630049M13"
                     /inference="alignment:Splign:2.1.0"
     exon            356..530
                     /gene="Pcyox1l"
                     /gene_synonym="C630049M13"
                     /inference="alignment:Splign:2.1.0"
     exon            531..587
                     /gene="Pcyox1l"
                     /gene_synonym="C630049M13"
                     /inference="alignment:Splign:2.1.0"
     exon            588..799
                     /gene="Pcyox1l"
                     /gene_synonym="C630049M13"
                     /inference="alignment:Splign:2.1.0"
     exon            800..940
                     /gene="Pcyox1l"
                     /gene_synonym="C630049M13"
                     /inference="alignment:Splign:2.1.0"
     exon            941..2081
                     /gene="Pcyox1l"
                     /gene_synonym="C630049M13"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2060..2065
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pcyox1l"
                     /gene_synonym="C630049M13"
                     /note="hexamer: TATAAA"
     polyA_site      2081
                     /gene="Pcyox1l"
                     /gene_synonym="C630049M13"
                     /note="major polyA site"
ORIGIN      
        1 acagtcgagc gccaaccgct agaggccgat ccggagcgtg ctgcccggtc accacccgcc
       61 atggcccgcg ctgccccgct gctcgccgtg ctggccacag tcctcaccac cgccgctgca
      121 ggcggagacg caccgccggg gaaaatcgct gttatcggag ctgggatcgg gggctctgct
      181 gtggcccatt tccttcagca acacttcgga ccccgagtgc aaattgtcgt ctatgagaaa
      241 gggactgtgg gtggccgcct ggccaccatc tccgtcaaca agcagaacta cgagagcggg
      301 gcggcctcct ttcactctct gagcctccac atgcaggact tcgtcaagct gctgggactg
      361 agacagcggc gcgaggtggt gggcagaagc gccatctttg gcggcgaaca tttcgtgctg
      421 gaggaaaccg actggtacct gctgaatctc ttccgcctct ggtggtacta cggcatcagc
      481 ttcctgaggc tgcagatgtg ggtagaggaa gtcatggaga agttcatgag ttctgaagca
      541 ctttgcaaac tcaggaactt tccaaggctg aagtgtgacg ggcgtaggat ctacaagtac
      601 caggctcacg gctatgcctt ctcgggggta gaagagctac tctactcact gggggaagcc
      661 acctttgtca acatgaccca gcggtccgtg gccgagtccc tgctccaggt gggcgtcaca
      721 cagcgcttta ttgatgatgt cgtctctgcg gtcctacggg ccagctatgg ccagtcggca
      781 tcaatgcccg cctttgctgg agccatgtcc ctagctgggg ctcagggcaa cctgtggtcc
      841 gtggaagggg gcaacaagct ggtttgttct ggtttgctga agctcgccaa ggccaccgtg
      901 atccacgcca cggtgacctc tgtgaccctg cacagtacag aagggaaagc cctgtaccaa
      961 gtggcgtacg agagtgacaa gggcaacagc tctgacttct acgacatcgt ggtcatcgcc
     1021 acgcccctgc acctggacaa cagcagcaac aacaacatca cctttgaagg ctttactccg
     1081 cccattgagg acattcaggg ctccttccag cccaccgtgg tctccctggt ccatggctac
     1141 ctcaactctt cctacttcgg tttcccggac cctaagcttt tccccttcgc caacatcctc
     1201 accacggact tcccgagctt cttctgcact ctggacaaca tctgtcccgt caacatctcg
     1261 gccagcttcc ggcggaagca accccaggag gccgccgtgt ggcgagtgca gtccccgaag
     1321 cccctcttcc gcacggagct gaagaccctc ttccgttcct attactcagt ccagacggcg
     1381 gagtggcagg cccaccccct ctacggctcc cgccgcaccc tcccgaggtt cgccctgcac
     1441 gatcagctct tctacctcaa tgccttggag tgggcggcca gctccgtgga ggtgacggct
     1501 gtagctgcta agaatgtggc tctgttggct tataaccgct ggtaccagga cctggataag
     1561 attgaccaga aggacctaat ccataaggtc aagactgaac tgtgagggct cccaggagag
     1621 cccagggact ctgcgccaca ctgaagataa ctgagatgga gcgcactcca gccgcgcagg
     1681 actgacgagg ccacacccat gggctctgtg gctttctctg ctctcatgga ttgaacaggg
     1741 tcccccatgt gggcccgggc gatctgctgt ctgcttatct aaggatcctc ttagaggctg
     1801 cctttttttt tttttttttt aaggagcgat taagaaaagg gaaggaaatt caagtcagtg
     1861 ttttggctgt ttttgttttt tgtttgtttg tttttgtttg ttttttgtgg tgttgggttt
     1921 tgaggttttt tgtttggttg gtttggtttt gggatcgtgt gtttatttta ttgtttttgt
     1981 tttggggggt tggtcgtttg ttgttttggg gggttgtttt gttttgtttg tttgttggtt
     2041 actgtttttc aagaagaaat ataaattcat cctccaagct a
//
