LOCUS       NM_025557               1575 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus Purkinje cell protein 4-like 1 (Pcp4l1), mRNA.
ACCESSION   NM_025557 XM_484933 XM_917594
VERSION     NM_025557.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1575)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1575)
  AUTHORS   Martinez,M.E., Pinz,I., Preda,M., Norton,C.R., Gridley,T. and
            Hernandez,A.
  TITLE     DIO3 protects against thyrotoxicosis-derived cranio-encephalic and
            cardiac congenital abnormalities
  JOURNAL   JCI Insight 7 (21), e161214 (2022)
   PUBMED   36166296
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1575)
  AUTHORS   Ye,Q., Bhojwani,A. and Hu,J.K.
  TITLE     Understanding the development of oral epithelial organs through
            single cell transcriptomic analysis
  JOURNAL   Development 149 (16) (2022)
   PUBMED   35831953
REFERENCE   4  (bases 1 to 1575)
  AUTHORS   Kurz,J., Weiss,A.C., Thiesler,H., Qasrawi,F., Deuper,L., Kaur,J.,
            Rudat,C., Ludtke,T.H., Wojahn,I., Hildebrandt,H., Trowe,M.O. and
            Kispert,A.
  TITLE     Notch signaling is a novel regulator of visceral smooth muscle cell
            differentiation in the murine ureter
  JOURNAL   Development 149 (4) (2022)
   PUBMED   35103284
REFERENCE   5  (bases 1 to 1575)
  AUTHORS   Martynova,E., Zhao,Y., Xie,Q., Zheng,D. and Cvekl,A.
  TITLE     Transcriptomic analysis and novel insights into lens fibre cell
            differentiation regulated by Gata3
  JOURNAL   Open Biol 9 (12), 190220 (2019)
   PUBMED   31847788
REFERENCE   6  (bases 1 to 1575)
  AUTHORS   Miller,J.A., Nathanson,J., Franjic,D., Shim,S., Dalley,R.A.,
            Shapouri,S., Smith,K.A., Sunkin,S.M., Bernard,A., Bennett,J.L.,
            Lee,C.K., Hawrylycz,M.J., Jones,A.R., Amaral,D.G., Sestan,N.,
            Gage,F.H. and Lein,E.S.
  TITLE     Conserved molecular signatures of neurogenesis in the hippocampal
            subgranular zone of rodents and primates
  JOURNAL   Development 140 (22), 4633-4644 (2013)
   PUBMED   24154525
REFERENCE   7  (bases 1 to 1575)
  AUTHORS   Morgan,M.A. and Morgan,J.I.
  TITLE     Pcp4l1 contains an auto-inhibitory element that prevents its IQ
            motif from binding to calmodulin
  JOURNAL   J Neurochem 121 (6), 843-851 (2012)
   PUBMED   22458599
  REMARK    GeneRIF: We speculate Pcp4l1 may be a latent calmodulin inhibitor
            regulated by post-translational modification and/or co-factor
            interactions
REFERENCE   8  (bases 1 to 1575)
  AUTHORS   Tripathi,P., Wang,Y., Casey,A.M. and Chen,F.
  TITLE     Absence of canonical Smad signaling in ureteral and bladder
            mesenchyme causes ureteropelvic junction obstruction
  JOURNAL   J Am Soc Nephrol 23 (4), 618-628 (2012)
   PUBMED   22282597
REFERENCE   9  (bases 1 to 1575)
  AUTHORS   Arlotta,P., Molyneaux,B.J., Jabaudon,D., Yoshida,Y. and
            Macklis,J.D.
  TITLE     Ctip2 controls the differentiation of medium spiny neurons and the
            establishment of the cellular architecture of the striatum
  JOURNAL   J Neurosci 28 (3), 622-632 (2008)
   PUBMED   18199763
REFERENCE   10 (bases 1 to 1575)
  AUTHORS   Bulfone,A., Caccioppoli,C., Pardini,C., Faedo,A., Martinez,S. and
            Banfi,S.
  TITLE     Pcp4l1, a novel gene encoding a Pcp4-like polypeptide, is expressed
            in specific domains of the developing brain
  JOURNAL   Gene Expr Patterns 4 (3), 297-301 (2004)
   PUBMED   15053978
  REMARK    GeneRIF: Pcp4l1 encodes a polypeptide with significant sequence
            similarity to the Purkinje cell protein 4 gene (Pcp40;it is
            expressed during mouse development.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY238909.1 and AY304481.1.
            
            On or before Sep 15, 2007 this sequence version replaced
            XM_917594.3, XM_484933.5.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY304481.1, AK002772.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                BY238909.1         1-29
            30-1575             AY304481.1         1-1546
FEATURES             Location/Qualifiers
     source          1..1575
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 79.11 cM"
     gene            1..1575
                     /gene="Pcp4l1"
                     /gene_synonym="1500036F01Rik"
                     /note="Purkinje cell protein 4-like 1"
                     /db_xref="GeneID:66425"
                     /db_xref="MGI:MGI:1913675"
     exon            1..258
                     /gene="Pcp4l1"
                     /gene_synonym="1500036F01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             250..456
                     /gene="Pcp4l1"
                     /gene_synonym="1500036F01Rik"
                     /note="PCP4-like protein 1"
                     /codon_start=1
                     /product="Purkinje cell protein 4-like protein 1"
                     /protein_id="NP_079833.1"
                     /db_xref="CCDS:CCDS48441.1"
                     /db_xref="GeneID:66425"
                     /db_xref="MGI:MGI:1913675"
                     /translation="MSELNTKTPPAANQASDPEEKGKPGSIKKAEEEEEIDIDLTAPE
                     TEKAALAIQGKFRRFQKRKKDSSS"
     exon            259..313
                     /gene="Pcp4l1"
                     /gene_synonym="1500036F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            314..1575
                     /gene="Pcp4l1"
                     /gene_synonym="1500036F01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1540..1545
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pcp4l1"
                     /gene_synonym="1500036F01Rik"
ORIGIN      
        1 tataaaaggt ggagccggtc aaggcgcccg gagctgctga caggaccagg tcagaagggg
       61 ctccctgagc agcgctgcag ccggagcatt tggggcagca ttaagcaaca gctcgcagcg
      121 tgcactctcc cctccgagcc ctccagggcc cctgccccgg agcccagcaa ctctcggccg
      181 cggttcacgc acgcatctcc gaggacccct tgcctcacct gcgcctgcca cgcccgtccg
      241 gccgccggga tgagcgagct taacaccaaa acacctccag cagccaacca ggcatctgac
      301 cctgaggaaa aagggaagcc tggcagcatc aagaaggccg aggaggagga agaaattgac
      361 attgacctga cagcgccaga gacagagaag gccgcccttg caatccaggg caagttccgg
      421 cgattccaga agaggaaaaa ggattccagc tcctgaatgg ccaggcctcc ccttaaccct
      481 tctacttcct ctctcccctc cacagctctg actctcacgt atctcattcc ttcatccctc
      541 tagcctctcc ccaaggcaag cttaaccttt atatattctt gtctcaggct ctcttaagcc
      601 atcacagtag tagaggcaca aggatgcgaa ggtgaagact ctagctggta gtcactaggc
      661 taagggtgga tcagtccatt taggagaaca aaaggttttg agatgtgaaa ttctcccctt
      721 tgcctaatgc taagggcagg agggggcaag ccctcagagt gcagagcctc aaggtggggc
      781 acatgtaggc ttctgccagt tgcaccatta acacttcagg caacactttc agctccctct
      841 gcacaactcc tcccatctcc cgtgtttcag ccctagtgca gctgcacttt ctcccgggct
      901 gacctaaatc caggagcttg caaaatgtgg ggtgcatgcc tttagtccca gaccttggaa
      961 ggcagaggca ggtggatctc tgtatgttcg agccagcctg gttgacatca tgagtcccag
     1021 gttagccaag gctacagaga ccctgtctca aaacagaaca aaacaaaaac caaaaaaacc
     1081 tacccatgca aaaataaata taaataaata aataaataag gcggcttact acactagtgc
     1141 atgctgagta gattcctccc aaggaaagag aactggggct ggtagaggca agggaggaag
     1201 agcttccttc accatccaga ctgaggtcag aagagccagt gatggcagaa ggttcaggga
     1261 cgacaggccg ggaaatgaaa actgagaaac gtttaggaag gaaagcagaa cgagatggtc
     1321 aagatgtctg aagctacaca ctattgttgt taacctaata ctccacgagg ggctctctgg
     1381 cctttgctaa cctgcctacc tctttacccg cccccatctc tagtcatccc tagagccatg
     1441 tgaaccaagt gacaccccta tagctctcag ccaccccact gtggagtcag ggcaaacatc
     1501 gccactgtat gtgactttag catgtttaat aatgatgaca ataaaaaaag ccctcaaatg
     1561 ggggcattga acctc
//
