LOCUS       NM_175561               7254 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus pecanex homolog 2 (Pcnx2), mRNA.
ACCESSION   NM_175561 NM_172917
VERSION     NM_175561.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7254)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7254)
  AUTHORS   Frankel,W.N., Mahaffey,C.L., McGarr,T.C., Beyer,B.J. and Letts,V.A.
  TITLE     Unraveling genetic modifiers in the gria4 mouse model of absence
            epilepsy
  JOURNAL   PLoS Genet 10 (7), e1004454 (2014)
   PUBMED   25010494
  REMARK    GeneRIF: By creating new Pcnxl2 frameshift alleles using TALEN
            mutagenesis, we show that Pcnxl2 deficiency is responsible for
            mitigating the seizure phenotype - making Pcnxl2 the first known
            modifier gene for absence seizures in any species
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ111064.1, BC068235.1, AK043903.1 and AK220342.1.
            
            On Nov 2, 2013 this sequence version replaced NM_175561.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-35                CJ111064.1         2-36
            36-753              BC068235.1         12-729
            754-3355            AK043903.1         115-2716
            3356-7235           AK220342.1         918-4797
            7236-7254           BC068235.1         5303-5321
FEATURES             Location/Qualifiers
     source          1..7254
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 73.65 cM"
     gene            1..7254
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /note="pecanex homolog 2"
                     /db_xref="GeneID:270109"
                     /db_xref="MGI:MGI:2445010"
     exon            1..389
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             237..6605
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /note="pecanex homolog protein 2"
                     /codon_start=1
                     /product="pecanex-like protein 2"
                     /protein_id="NP_780770.2"
                     /db_xref="CCDS:CCDS52708.1"
                     /db_xref="GeneID:270109"
                     /db_xref="MGI:MGI:2445010"
                     /translation="MASQVLQLLRQGVWAALTGGWYHDPEHSKFTNSCHLYLWLFLLL
                     LPLALHLAFPPNVLTALFYCGSVTIFFAVIKLISYRLHLMFDKGEAIQHRSPRKRSKR
                     KPEGEASSQHTARHKNPSNNRQIHSTKKEEPRGSLTTPPLCCSSRGQSVHSQHSSGPL
                     ELPAQETVEDLKGVVLSEDQPEALASSTSPGMKSESLPASQGRTPEPTPRPACPLKPV
                     TTELFTARKGKESGGTAQRPARHRSESGLVNPGALKKLPQLSLSQYDLLETDISFQPW
                     GSEHSVLLPQPNCTQGATRAQPQNRSPQDSLSSSCCQCNTVLAKPTEEELTRTSGQVE
                     LPLNQEVVDSDGEVAVTLIDTSQPGEPLSLHEPIKIVITMSSTQNSISDLESSLHLRV
                     TSSDRTSVRSSAESAGSGGAGPADPEQVRIPLITLELTEDGGGRGVSCSEGNGGERTP
                     ERMEVMSPDRCSGSGPGDGSPTPGSTLATLTPRVDPESEGSKEGQANLDPASCKSSHE
                     KRHARVLSVDSGTDVFLSRSTKEVVSDGEKPIPTSKSDLEAKEGQIPNESNFLEFVSL
                     LESISTSKVVAPDSPAEQKGASQGPEGHASPGTKEEAVENEKPNGRDPKPGKPDLPSQ
                     DPANGSPVFTQPAKSAALFQGSRQRHIIYRVTSQQDSSVLQVISGPETSVQEEMSLDA
                     MHVFIDEHGEVRSCYLKSGNQKEGSSQHPPLNPDCVSHARGILLSSSSSTATGSPDPS
                     SGDPAVSALQQQLLLMVARRTQSETPRHVSQDLEDSSRSSAQGKFNREQFYKFIVFPG
                     KWIKVWYDRLTLLALLDRTEDVKENMVAVLLSVLVSLLGFLTLNRGFCRDLWVLLFCL
                     VMASCQYSLLKSVQPDPASPIHGHNQIIAYSRPIYFCMLCSLILLLDAGAKAKHPPSY
                     VVYGLKLFTPETLQAVRDHLIVFLCCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGS
                     AVSGITSAVYSVGRSVLAAALLHAFCFSAVKEPWSTQHIPALFSAFCGLLVALSYHLS
                     RQSSDPSVLLSFIQCKLLPKCLHQNLEESATDPLPQRMKDSVKDVLRSDLVICSAAAV
                     LSFAVSASTVFLSLRPFLSIVLFALAGTVGLITHHLLPQLRKHHPWMWISHPVLRSKE
                     YQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLDAFSISNYRRLGTHWDI
                     FLMITAGMKLLRTSFCNPVHQFANLGFTVIFFHFDYKDISESFLLDFFMVSIVFTKLG
                     DLLQKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPHSAMLFFQTFATSIFSTPLSPFLG
                     SVIFITSYVRPVKFWERSYNTRRMDNSNTRLAVQMERDPGSDDNNLNSIFYEHLTRTL
                     QESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNGLVTFQLRGLEFRGTYCQ
                     QREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTWEITRTQYILEGYSIID
                     NNAATMLQVYDLRRVLIRYYVKSIIYYMVTSPKLVSWVKNESLLKSLQPFAKWHHIER
                     DLAMFNINIDDDYVPCLQGITRASYCNVFLEWIQYCAGKRQELSKTLEHVDSDEDSAL
                     VTLAFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVTARDEWVFADMDLLH
                     KVVVPAIRMSLKLHQDQFTCPDEYEDPAVLYEAIRSFAKKVVICHEGDPAWRGAMLSN
                     KEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWAGQQQELIFLRNRN
                     PERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQSVWGGPVTLNRV
                     RTWFQTRWLRMRKDCSVGQRSGGGNIEDGEGGAVPSAGGGSAPNGESRDGSTEQPRKG
                     GTQQWSSPRGEAQRAGRRKGRSQSVQAHSAISQRPPTLSSSGPILESHQAFLQTSTSV
                     HELAQRPSGSRLSLHTSAASLHSQPPPVTTTGHLSVRERAEALIRSSLGSSTSSTLSF
                     LFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAAGHAARHFSEPCEPT
                     DSPEQGQLQDGRLAEAMEENLGVLCRRASQEDMGLDDTASQQSTSDEQ"
     exon            390..595
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            596..716
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            717..753
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            754..2013
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2014..2161
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2162..2307
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2308..2401
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2402..2537
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2683
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2684..2837
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2838..2870
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..3042
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            3043..3153
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            3154..3245
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            3246..3355
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            3356..3452
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            3453..3545
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            3546..3696
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            3697..3838
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            3839..4016
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            4017..4125
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            4126..4255
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            4256..4314
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            4315..4530
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            4531..4784
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            4785..5018
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            5019..5140
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            5141..5285
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            5286..5516
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            5517..5791
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            5792..5982
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            5983..6431
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     exon            6432..7236
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7218..7223
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /note="hexamer: ATTAAA"
     polyA_site      7236
                     /gene="Pcnx2"
                     /gene_synonym="A830048P05; E330039K12Rik; mKIAA0435;
                     Pcnxl2"
                     /note="major polyA site"
ORIGIN      
        1 gggaaaatcc tccttccctt ggacatggcg cgcacctgcc tggcagcccc agccggctcc
       61 agcaccgcgc tgtgccggtc cgtactgttc agcgtctacc gcggtttggg cggtggcggc
      121 gggggtggga ccgcgcctgg agcacaccgg cacgcgccga cgtactgagc tccagggtgc
      181 tgagcttagg gtgctgagcc ccagggcacg ctcggtttct gccggactct gcgggcatgg
      241 cgtcccaggt gctgcagctg ctcaggcagg gtgtgtgggc cgctctcaca gggggctggt
      301 accacgaccc ggagcatagc aaattcacca atagctgcca cctctacctg tggctgttcc
      361 tgctcttgct gccactggct ctgcacctgg cttttcctcc aaatgtcctc acagcgctgt
      421 tctactgcgg ctctgtgacc atcttctttg cagtcatcaa gcttatcagc taccgcctgc
      481 acctcatgtt cgacaaggga gaagcaatcc agcaccgatc cccaagaaag agaagcaagc
      541 ggaagccaga gggagaggcc agcagccagc acaccgccag gcacaaaaac ccaagcaata
      601 acaggcagat tcacagcacc aagaaggaag agcctcgagg gagcttgacc acaccacccc
      661 tctgctgcag ctcccgaggg cagagtgtcc actcccagca ttcctcgggg ccattggagt
      721 tgccagcaca ggagacagtg gaagacctca aaggtgtcgt tctgtcagaa gatcaacctg
      781 aggcactggc gtcatctacc tcacctggca tgaagtcaga aagtctaccc gcctctcagg
      841 ggcgtacacc agaacccact cccagaccgg catgcccact gaagccagtt accacagaac
      901 tcttcacagc aagaaaaggg aaagagtcag ggggcactgc ccagcgccca gcccgccaca
      961 ggtccgagag tggcctggtg aaccctggag ccttgaagaa gttgccacag ctgtcattgt
     1021 cccagtatga cttactagaa actgacatct ccttccagcc atggggcagt gagcactcag
     1081 ttctgcttcc acagcccaac tgtacccagg gcgccacccg ggcacagcca cagaacagat
     1141 cgcctcagga cagcctgagc agcagctgct gtcagtgcaa cacagtccta gccaaaccca
     1201 cagaggagga gctgaccagg acatccgggc aggtggaact gcccttgaac caggaagtgg
     1261 tcgactcaga cggcgaggtt gcagtgactc tcatcgacac ctcccagcct ggagagccac
     1321 ttagtcttca cgaacccatt aagatagtaa tcaccatgag cagcacccaa aactccatca
     1381 gtgacctgga gagctccctg cacctgaggg taaccagctc tgacagaacc agtgtcaggt
     1441 ccagtgcaga gtctgctggc tcaggagggg ccggtcctgc tgacccggag caggtcagaa
     1501 tccctttgat cacccttgag ttaacggagg atggaggagg aagaggcgtc tcttgttctg
     1561 aagggaatgg gggagaaagg accccagaga gaatggaggt gatgtcgcct gatcgttgtt
     1621 ctggctctgg gcctggggat ggaagtccca ccccaggctc cacgcttgcg acactcacac
     1681 ccagggtgga ccctgaatct gaggggagca aggagggcca ggcaaacctg gacccagcct
     1741 cttgtaagag cagccatgag aaaaggcatg cccgtgtgct cagtgtggac agcgggaccg
     1801 atgtctttct gagcaggagt accaaagaag tggtcagtga tggcgagaaa cccatcccaa
     1861 cctccaagtc agacctggag gccaaggaag gacagattcc aaatgaatcc aatttcctgg
     1921 agtttgtctc cctgttggaa tccatcagta catctaaggt ggtggcgccc gactccccag
     1981 ctgagcagaa aggagcaagt cagggccctg aaggtcatgc ctccccaggg accaaggagg
     2041 aagctgtgga gaatgaaaaa cccaacggac gtgatcccaa gccaggaaaa ccagacttgc
     2101 caagccaaga ccctgcaaat ggtagcccgg tgttcacaca gcctgccaag tccgcagcac
     2161 ttttccaggg tagccggcaa aggcacatca tctaccgagt gacttcccaa caagacagct
     2221 cggtgctgca ggtcatcagt gggccagaaa cgtctgtgca ggaggagatg tccctggacg
     2281 ctatgcatgt tttcatcgat gaacacgggg aagtcagatc ctgttactta aagtctggaa
     2341 atcagaaaga aggctcctct cagcatccac ccttgaaccc cgactgtgtg tctcatgcca
     2401 gagggattct tctcagctcc tccagcagca ccgctacagg aagtccagat ccatcctcag
     2461 gggaccctgc agtcagcgcc cttcaacagc agctgttact catggtagct cggaggacgc
     2521 agtcagaaac accacggcac gtcagtcagg atctggaaga ctcatcacgc tcctcggcac
     2581 aagggaagtt taaccgagag cagttttaca agttcatcgt cttccctggg aagtggatta
     2641 aagtctggta cgaccgactc actttgttgg cgttgctgga tcgaactgaa gatgtgaagg
     2701 agaacatggt agcagttctg cttagtgttc tggtttctct cctgggcttt ctgacactga
     2761 atcgtggctt ctgcagagac ttatgggtcc tgcttttctg cttggtcatg gccagctgcc
     2821 agtactccct gctcaagagc gtccagcctg accctgcctc accaatacac ggtcacaacc
     2881 aaatcatcgc ctatagcaga cccatctatt tctgtatgct gtgcagcctt attttgcttc
     2941 ttgatgcagg ggccaaagcc aaacaccctc ccagctatgt cgtgtatggc ctgaagctct
     3001 ttacaccaga gaccctgcaa gcagtcaggg accacttaat agtatttttg tgttgcttcc
     3061 ctgctatctc cctcctcggg ctcttcccac agatcaacac cttctgtacg taccttctgg
     3121 aacaaatcga catgctgctc tttggaggtt ctgctgtttc tgggatcaca tcggctgtgt
     3181 acagcgtggg ccggagtgtc ctggcagcag ccctgctcca tgctttctgc ttcagtgctg
     3241 tgaaggaacc atggagcaca cagcacatcc cagcactgtt ctcggccttc tgcggcctcc
     3301 tggtcgccct gtcctaccat ctgagccggc agagcagtga tccttccgtg ctcctgtcct
     3361 tcattcagtg taaattgctt cctaaatgtt tacatcagaa cctggaagag tcagctacag
     3421 accctctccc tcagaggatg aaggattcag tgaaggatgt cctgagatca gaccttgtca
     3481 tctgctcagc cgctgctgtg ctctcctttg cagtcagtgc cagcactgtc ttcctgtcct
     3541 tacggccttt tctcagcatc gtgctctttg ccctggcggg caccgtgggg ctcatcaccc
     3601 accatctgct ccctcagcta cggaagcacc acccctggat gtggatctca catcctgtgc
     3661 tcaggagcaa ggagtaccag cagcgggagg caagagatat tgctcactta atgtggtttg
     3721 agagactcta cgtgtggctt cagtgtttcg aaaagtatct cttgtacccg gccatagtcc
     3781 tgaacgccct cactcttgat gctttctcta taagcaacta caggagactc ggcacccact
     3841 gggacatttt tctgatgatc accgcgggca tgaagctgct gaggacgtca ttctgtaacc
     3901 ccgttcacca gtttgccaac ttgggtttca cggtcatctt tttccacttt gactacaagg
     3961 acatctctga gagcttcctc ctggattttt tcatggtgtc cattgtcttc acaaagcttg
     4021 gggatctgct tcagaagctg cagtttgtcc tggcctacgt ggccccttgg cagatggcct
     4081 ggggctcttc cttccacgtg tttgcccagc tcttcgccat ccctcactcc gccatgcttt
     4141 tcttccagac attcgccacc tcaatcttct ccacgcccct gagtccgttc cttgggagcg
     4201 tcatattcat cacgtcctac gtcaggccgg tgaagttctg ggagagaagc tataatacaa
     4261 ggcgcatgga taattccaac acaaggctgg ctgtgcaaat ggaaagagac ccagggagtg
     4321 atgacaacaa cctcaactcc atcttctacg agcacctgac tcggaccctg caggagtcgc
     4381 tctgtggaga cctggtgctt ggccgctggg gcaactacag ttctggtgac tgcttcattt
     4441 tggcctcgga tgacctcaac gccttcgtcc acctgattga aatcggaaac ggtctcgtca
     4501 cctttcagct tcggggactg gagttccgag gaacctattg ccagcagagg gaggtggagg
     4561 ccatcatgga gggtgatgag gatgacagag gctgctgctg ctgcaaaccc ggccacctgc
     4621 cacacctgct gtcctgcaat gctgccttcc acctacgctg gctcacctgg gagatcacgc
     4681 gcacacagta catcctggag ggctatagca tcatcgataa caacgcagcc actatgctgc
     4741 aggtgtacga cctccgcagg gtgctcatcc gctactacgt caagagcata atatactaca
     4801 tggtcacttc tcccaaactc gtctcgtggg tcaagaatga atccctgctg aagtccctgc
     4861 agccctttgc caagtggcat cacatcgagc gtgaccttgc catgttcaac atcaacatcg
     4921 atgatgacta cgtcccgtgt ctccagggga tcacccgggc gagttactgc aacgtgttcc
     4981 tggagtggat tcagtactgc gcagggaaaa gacaggagct ctccaagacc ctggagcacg
     5041 tggacagtga cgaagactcg gctctggtga cacttgcctt tgccctgtgc atcctgggaa
     5101 ggcgagctct gggaacagct gcacataaca tggccatgag cctagactca ttcctctacg
     5161 gcctgcacgc cctcttcaaa ggtgacttcc gggtcacggc tcgagacgag tgggtatttg
     5221 ctgacatgga cctgctacac aaagttgttg ttccagccat ccgaatgtcc ctgaaactgc
     5281 accaggacca gttcacctgc cccgatgagt acgaagaccc cgcggttctc tatgaggcca
     5341 tccggtcctt cgcgaagaag gtggtgatct gccacgaggg agacccggcc tggcgaggag
     5401 ccatgctgtc caacaaggag gagctgctga ctctgaggca cgtggtggac gagggcgccg
     5461 atgagtacaa ggtcatcatg ctccacaggg gcttcctgag cttcaaggtc atcaaggtga
     5521 acaaggagtg cgtccgagga ctctgggcgg ggcagcagca ggagctcatc ttcctgcgca
     5581 accgcaaccc cgagcgcgga agcatccaga acaacaagca ggtcctgcga aacctcatca
     5641 actcgtcctg tgaccagccg ctgggctacc ccatgtatgt ctccccgctg accacgtcct
     5701 acctgggcac ccacaagcag ctgcagagtg tctggggcgg acctgtcaca ctgaaccgtg
     5761 tgaggacgtg gtttcagacg aggtggctga gaatgagaaa ggactgcagt gtgggccagc
     5821 ggagtggtgg tggcaacatt gaagatggag agggtggagc tgtaccatca gcgggtggcg
     5881 gtagcgcccc taatggcgag agccgggacg gcagcacaga acaacccagg aaaggaggca
     5941 cccagcagtg gtcctcaccc cgtggagagg ctcagagggc aggcagaagg aagggcagaa
     6001 gccagtccgt ccaggcacat tcagcgataa gccagaggcc acctactctg agctcctcgg
     6061 gtcccatcct agagagccac caggccttcc ttcagacttc cacatctgtg catgagctag
     6121 cgcagagacc ctcaggcagc cggctctcct tgcacacctc agctgcatct ctgcactccc
     6181 agccgcctcc cgtcaccacc acgggccacc tgagtgtccg agagcgggcc gaggcactca
     6241 ttcggtctag cctgggctcg tcaaccagtt ctactctcag cttcctcttt gggaaaagga
     6301 gcttctccag cgcactcgtc atatctggac tctctgctgc agaggggggc aacaccagcg
     6361 acacccagtc atccagcagc gtcaacattg tgatgggtcc ctccgcgagg gccgcgggcc
     6421 atgctgctcg gcacttctca gaaccatgtg aacccactga cagcccagag caggggcagc
     6481 ttcaagatgg acgcctggca gaggctatgg aggagaacct gggggtgttg tgccggagag
     6541 caagccagga ggacatgggc ctggatgata cggcttctca gcagagtacc tccgatgagc
     6601 agtagtagaa cacacgtctg gtgtgagaga gatggcgact cttccccctg ctccaaagcc
     6661 acattggttc ttcccagggg gggaaaggca gagctgttct agaaaaacgt taaggttaac
     6721 tcaggttttg aaaacactcc cacaccatgg gggctgggga gaagacattt tacctcctcc
     6781 ctccagcacc gctcaaaagt tggacatttc tcacaaaagc catgttatat ctcaaaacaa
     6841 ctagagtgcg tagtagggcc cgtgactagc agctccttcc tgcgctggtt aaattagaac
     6901 agctgcatgc taagttattg gcactttaca cgttactgtc accatgtgag agcaccggag
     6961 tcgcggctcc taggccagca gtgggaggtc agaggccttc gagcctcgtt ctttatcaca
     7021 gctgtgagtg caagtcacta gcaacagcct ggtggttcat gggtcccagg tgagaggtta
     7081 gaggtgacat gctcttctct ctcaagttct gggccacctg ggacccctgc gggcttcccg
     7141 gaaacgcatg ctctgtcttc caagctgatt aagctctact gtacgtgagc acatttgcac
     7201 agacctttgt tttagggatt aaaatgttta cagttaaaaa aaaaaaaaaa aaaa
//
