LOCUS       NM_001024622            2300 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus PEST proteolytic signal containing nuclear protein
            (Pcnp), transcript variant 4, mRNA.
ACCESSION   NM_001024622 XM_132579 XM_358858
VERSION     NM_001024622.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2300)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2300)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2300)
  AUTHORS   Halle,M., Liu,Y.C., Hardy,S., Theberge,J.F., Blanchetot,C.,
            Bourdeau,A., Meng,T.C. and Tremblay,M.L.
  TITLE     Caspase-3 regulates catalytic activity and scaffolding functions of
            the protein tyrosine phosphatase PEST, a novel modulator of the
            apoptotic response
  JOURNAL   Mol Cell Biol 27 (3), 1172-1190 (2007)
   PUBMED   17130234
REFERENCE   4  (bases 1 to 2300)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY287179.1, BC061235.1 and BC106192.1.
            
            On Mar 18, 2006 this sequence version replaced NM_001024622.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC023320.1, AK152279.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                BY287179.1         1-36
            37-761              BC061235.1         1-725
            762-2300            BC106192.1         671-2209
FEATURES             Location/Qualifiers
     source          1..2300
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 33.77 cM"
     gene            1..2300
                     /gene="Pcnp"
                     /gene_synonym="1110018D06Rik"
                     /note="PEST proteolytic signal containing nuclear protein"
                     /db_xref="GeneID:76302"
                     /db_xref="MGI:MGI:1923552"
     exon            1..115
                     /gene="Pcnp"
                     /gene_synonym="1110018D06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..588
                     /gene="Pcnp"
                     /gene_synonym="1110018D06Rik"
                     /note="isoform 4 is encoded by transcript variant 4;
                     PEST-containing nuclear protein"
                     /codon_start=1
                     /product="PEST proteolytic signal-containing nuclear
                     protein isoform 4"
                     /protein_id="NP_001019793.1"
                     /db_xref="CCDS:CCDS37357.1"
                     /db_xref="GeneID:76302"
                     /db_xref="MGI:MGI:1923552"
                     /translation="MADGKAGEEKPEKPQRAGAAGGPEEEAEKPVKTKTVSSSNGGES
                     SSRSAEKRSAEDEAADLPTKPTKMSKFGFAIGSQTARKASAISIRLGASKPKETVPTL
                     APKTLSVAAAFNEDEDSEPEEMPPEAKMRMKNIGRDTPTSAGPNSFNKGKHGFSDNQK
                     LWERNIKSHLGNVHDQDN"
     exon            116..330
                     /gene="Pcnp"
                     /gene_synonym="1110018D06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            331..405
                     /gene="Pcnp"
                     /gene_synonym="1110018D06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            406..461
                     /gene="Pcnp"
                     /gene_synonym="1110018D06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            462..2271
                     /gene="Pcnp"
                     /gene_synonym="1110018D06Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggccgtga cgttcttgcc cgggctgcag ggggaggccg cggcgaggaa gatggcggac
       61 gggaaggcgg gagaggagaa gccagagaag ccgcagcgag ccggagccgc cggaggacct
      121 gaagaagaag cagaaaaacc tgtgaaaact aagactgttt cttccagtaa tggaggggaa
      181 agttccagtc gcagcgctga aaagcgatca gctgaagacg aagctgcaga cctcccaaca
      241 aagcctacaa agatgtccaa gtttggattt gccataggta gtcagacggc acggaaagcg
      301 tccgccatct ccattagact cggagcaagt aagcctaagg aaacagttcc aactcttgct
      361 ccaaaaactc tgtcggtagc agcagctttc aatgaagatg aagatagtga gccagaagaa
      421 atgcctccag aagcaaagat gaggatgaag aacattggaa gggacacacc aacatcagcg
      481 ggaccaaact cctttaataa agggaagcat ggcttttccg ataaccagaa gctgtgggag
      541 cgaaatataa aatctcatct tggaaacgtc cacgaccaag acaattaagt gaagtgtctg
      601 agactggggt gtgggtgggt gcagttagaa ggagcagtct cctttttgta aagaatggtg
      661 taagactagc tttggagccg tttttctttc ttcttttttt cttttccttt tttctttttt
      721 tttttttttt tttaagattg agtggtacac taataaatga gagtttgcaa ttagaggtaa
      781 tttatgtttt atatacagat ttcaagacat ttgctaattt tgtagtttca catgattagt
      841 ttccaagggt tacagataat aaagaaatca caagtggtac ctttctaaga attgcatatt
      901 tttttagaca caactattag cacattaaga gggaagccaa aagttattgt ctgcttcaaa
      961 ctggaagcag ttcctctcct gacttctccc tcgttacccg actgtccggc tccctgcagc
     1021 agccttaccg agagggagat tggcttgaga agccagtgtt actgttgtga ctgttggctg
     1081 agaggaagtt tagatgaggt tcaagtaaac cctttcctgc gggcatttcg ttttgtttcg
     1141 ggccattcta gctagtactg cttcgctctc agtgggtacc gatgcttgct ctgtaaaaat
     1201 aaattttttt cgttaaaaat tcttatatga agaattgagt attatgacta gcccactcta
     1261 acggagtgtg tctccgttga ggaccttcag aggacactat ttgctaccaa agtgaaccag
     1321 tattctgaat gtgcttctct tggtttctgt tctagttcct agaagcattt ccaccagaac
     1381 ttgaggcaaa acataaggaa gctgtttctt ttaaagtaca aacaccacca aaaatatcag
     1441 tgtacatagt gctttatgta tttggctggc ttttattttt taaaaggttt aaataacaaa
     1501 aaaggaaaaa aaggtatagc attgtatgaa ggcagatgag gcgacacacc tgtgacattt
     1561 gaagcatttg tgttactaac ttactagatc cggtttgaat tgaattcaca aggtttctta
     1621 cttgtccaac tccaggctta ttttacgtac atacaacctg accagtggtt tcaaaagcac
     1681 atttagtgac tgcaatagga cagaaatgct tctctagaca catcttcatt gcgagcgtct
     1741 catcgcatat gctcttagag ttctgaatgt aggatgtttg ttttgtattt ttgtattgta
     1801 tatgggcttt ttaaatgtga cagttaaatg catctttaat agtcacagac aaaagagatg
     1861 ataaaatgtc ctttgaaaat ggcaatgttg agtttggagg cagcttcggg gagtttcctg
     1921 ggtggcgatg attcactggg cagtttttaa tgtagtgact tcaagaagca gcctgcggat
     1981 attcctaaca cttggttcac tacagtttag tttacttcat aagccccaag taaaacgatg
     2041 gaaatgtaca tagcactatt agttcataca tgatttaagt atatcaagat acataaattt
     2101 aacatttatg tctgcaaact gtccatttgt ccattttact gtttgttgaa ataacacctc
     2161 tcctacatat tctttacttg actcgaataa caaattaacc tgacgtcaag atggagagag
     2221 acgactgagc tgaatgtctt tactaaaatt acaataaatt ttgtcaaact taaaaaaaaa
     2281 aaaaaaaaaa aaaaaaaaaa
//
