LOCUS       NM_183028               5235 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus protein-L-isoaspartate (D-aspartate)
            O-methyltransferase domain containing 1 (Pcmtd1), mRNA.
ACCESSION   NM_183028 XM_984646
VERSION     NM_183028.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5235)
  AUTHORS   Knupp,D., Cooper,D.A., Saito,Y., Darnell,R.B. and Miura,P.
  TITLE     NOVA2 regulates neural circRNA biogenesis
  JOURNAL   Nucleic Acids Res 49 (12), 6849-6862 (2021)
   PUBMED   34157123
REFERENCE   2  (bases 1 to 5235)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   3  (bases 1 to 5235)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 5235)
  AUTHORS   Warden,C.H., Mehrabian,M., He,K.Y., Yoon,M.Y., Diep,A., Xia,Y.R.,
            Wen,P.Z., Svenson,K.L., Sparkes,R.S. and Lusis,A.J.
  TITLE     Linkage mapping of 40 randomly isolated liver cDNA clones in the
            mouse
  JOURNAL   Genomics 18 (2), 295-307 (1993)
   PUBMED   8288233
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY282003.1, AK168606.1, AK018402.1 and AI462192.1.
            
            On Apr 25, 2007 this sequence version replaced NM_183028.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC110360.1, SRR1660817.298126.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-249               BY282003.1         2-250
            250-4342            AK168606.1         2-4094
            4343-5183           AK018402.1         198-1038
            5184-5235           AI462192.1         1-52                c
FEATURES             Location/Qualifiers
     source          1..5235
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 2.08 cM"
     gene            1..5235
                     /gene="Pcmtd1"
                     /gene_synonym="8430411F12Rik; A030012M09Rik"
                     /note="protein-L-isoaspartate (D-aspartate)
                     O-methyltransferase domain containing 1"
                     /db_xref="GeneID:319263"
                     /db_xref="MGI:MGI:2441773"
     exon            1..297
                     /gene="Pcmtd1"
                     /gene_synonym="8430411F12Rik; A030012M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            298..719
                     /gene="Pcmtd1"
                     /gene_synonym="8430411F12Rik; A030012M09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             413..1486
                     /gene="Pcmtd1"
                     /gene_synonym="8430411F12Rik; A030012M09Rik"
                     /codon_start=1
                     /product="protein-L-isoaspartate O-methyltransferase
                     domain-containing protein 1"
                     /protein_id="NP_898849.1"
                     /db_xref="CCDS:CCDS35508.1"
                     /db_xref="GeneID:319263"
                     /db_xref="MGI:MGI:2441773"
                     /translation="MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLE
                     GYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLIL
                     GPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQY
                     DRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAP
                     LVQPSKNDNGTPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKR
                     KRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDSKEEEEKEHIEAMKREEPPQNLL
                     REKIMKLPLPESLKAYLTYFRDK"
     exon            720..822
                     /gene="Pcmtd1"
                     /gene_synonym="8430411F12Rik; A030012M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            823..994
                     /gene="Pcmtd1"
                     /gene_synonym="8430411F12Rik; A030012M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1118
                     /gene="Pcmtd1"
                     /gene_synonym="8430411F12Rik; A030012M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..5232
                     /gene="Pcmtd1"
                     /gene_synonym="8430411F12Rik; A030012M09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4323..4328
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pcmtd1"
                     /gene_synonym="8430411F12Rik; A030012M09Rik"
                     /note="hexamer: AACAAA"
     polyA_site      4349
                     /gene="Pcmtd1"
                     /gene_synonym="8430411F12Rik; A030012M09Rik"
ORIGIN      
        1 ggcatctttc ttcggagggc gccccgcgca cgcgcagctc ccaggaggcg gtggcgacta
       61 gggcagtcca gctgcccggg tcccgggttg cgggtcgggc tccgccctcc cgcgtcggcg
      121 ctggcggacg ctgtgccggg ccagtcggct gtctctgcgg cgctccgccc gccgccggtc
      181 cgccgctgct ttggcctgga gggctcccgc ctacgcaggc tcgtgacgcg ggggctggga
      241 cggggcttca gggactgagc gggcgctgcc gctgtgtgag cgtcttctgc gccttcggtt
      301 taatttattt ttggaaatca agttcaatat taaaaagaaa gagcacacat tattggaagc
      361 catttctact aattcgttac attttaactt atgatttgat ttgaatactg tcatgggagg
      421 agctgtgagt gctggggaag ataatgatga cttaattgat aaccttaaag aagctcagta
      481 catccgaact gaaagagtag agcaagcctt cagagccatt gaccgcggag attactatct
      541 ggaaggctac cgagacaatg cttacaaaga cttagcctgg aagcacggga acatacactt
      601 gtcagcacct tgcatttatt ctgaagttat ggaagctttg aaacttcaac caggattatc
      661 ttttcttaac ctgggaagtg gaaccggata tttaagtaca atggtgggct taattttagg
      721 tccttttgga ataaatcatg ggattgaact tcattcagat gtggtggagt atgccaagga
      781 aaaactggag agcttcatca aaaatagtga tagctttgat aaatttgaat tctgtgaacc
      841 cgcatttgtg gtgggtaatt gccttcagat agcttctgac agtcatcagt atgatcgaat
      901 ttactgtgga gctggagtcc agaaagacca cgaaaactac atgaagatct tactcaaagt
      961 tgggggcata ttggtcatgc ctatagagga tcagttgaca cagattatgc ggactggaca
     1021 aaacacttgg gaaagtaaaa atatccttgc ggtttccttt gcaccactag tacagcctag
     1081 taagaatgat aatggcacac cggactctgt ggggctccct ccatgtgctg tcaggaatct
     1141 ccaagacttg gctcgcattt acattcgacg tacacttaga aacttcataa atgatgagat
     1201 gcaggccaag gggattccac aaagggctcc acccaagagg aaaagaaaga gagttaaaca
     1261 gagaattaat acttacgtat ttgtgggtaa tcagcttatc cctcagcctc tagacagtga
     1321 agaggatgaa aaaatggaag aagacagcaa agaagaagag gagaaagagc acatcgaagc
     1381 catgaagcgc gaggaaccac ctcagaacct actgagggaa aagataatga agctgccact
     1441 cccagagtct ttaaaggctt acttgacata ttttcgagac aaataactta aacaaggaag
     1501 aatgcctact gataaactcc cttactcttg taaatgtagt attaattagg acttagagaa
     1561 ttacttcatt agaatgaatt attgcagaaa aaagtctaag ttatttcttt taataacaga
     1621 aatgatgtat tcagtgattt aaaagagtct ctttcctaag atctattttt cttaaatctt
     1681 gaagaattac tgttttgatc tcaaagtggg atgggtcaat agtaagaact ttgtatacag
     1741 tactctttct ggttcttcat ggatttgtag tgttggcaat tgaatttcat tctataagag
     1801 gttgatacac atattgtcac acatataggc ttatttaaat tgccgtttgc atttctgtta
     1861 cttgagcttg cttatctaat aaggaaagca aatgcttgta gacctactta ccttacttat
     1921 gttctagaca tattccgggc aacgtatgag tgcaatacta attcaagata ctgagtaatt
     1981 tagctttaaa aaccacagac ttcatgaaat tttacagacc cgaaacttaa gcttttgaat
     2041 ctattgccaa aaggcatggg gaaaatttct gcttctctca tagagatttt taagagctag
     2101 tgaatgttaa agtaggaagt ggctacttga cacaactagt ttgtatgggc cctttgtgtt
     2161 ctcagtattt aaagataatg aggttatctt aactatagaa ttttaagcgg tagtatattt
     2221 aggattgctt ttctataaat aactataaag tattagattt ggaaagtcat tcactgtccc
     2281 atttgcttct aaatgcagac tgtgaataag tcacattaag tgatcagcac tgcttaggga
     2341 cctccagcag cagggggaat gatatgatca gtagagacat tttagcagtg gaacttttca
     2401 ttaagtagat atttatcttt gacaaggtag gccacactgg cctcatctgc tctgaatctt
     2461 tctaatataa atagtcatgg gagttgtatg tagatgcgtt tgtgttaaaa cttgcttcag
     2521 aatcagagtg ggatctctgg gacctatacc aaactcatta tccttcattc tgtattttgt
     2581 ttctttgata gaatgatgat gattttcact ttttgcttaa tactacattc ttaagctact
     2641 tacatagggt atcagtgata caccaggcag tgcatgtcat tactagttct ttcttcctgg
     2701 tagggcctgc acagttattc ctggttaaga agctgtggga tgtgacctac ttactgctta
     2761 ccatcacacg gaagggaaga tttcaagtgt ctcacttatt cccaccacat cactgtcaga
     2821 gcaccctctc ggatttacat aaggaagtac aatcatgatg attcaaatag tttataactc
     2881 aggtccaata attctgtgta ggtgatcagt taaaacagtt taaagatgaa attgacccaa
     2941 ataattgata atgttttaat aatgtgaaca acagtgttat ggaaaggatt cgtttgactc
     3001 ttgtgaaatg ggcctgtatg atttttctta atgtaattag taaacaaact attattaaga
     3061 tatgctctat cctgtttctg tccaaaaaag aaaaaagaca tctccctctc tctgacgtgg
     3121 tactgggggt taaacccagg accaggacct cttgcatgct aggcaagcac tctacaaatg
     3181 agatatatcc ctagaccaac atactctttt attcttttta aaattttgtt taagaagttt
     3241 aatcttgaac tcctgatacc cacatagtct tatctgggaa gagttgtcat ttattttcca
     3301 ttctgtcacc cacatctctt tacttttctc ttaagagctt gatgtacaga aaactgaaaa
     3361 tatgtaatgc tcagtgatct tattatttag gagtgttttg actgatatat ttaaagatag
     3421 attatattca tgctgtcttc tgttgacttt gagaaattgt acagtagatt gtcttgatca
     3481 ttgcatttgt tgtctttgaa atgtatattt tgtcatttta aattcattta cttttcaggt
     3541 gtgactttat ggttgacttt taaaggtagg gatagatgaa aatttaagga aagctatctt
     3601 atctatcaac tcggatgcat tagattaaga atatttgggt tcgggcttat ttttatttga
     3661 gtgtggaaag ttatgcttta taagtaaaga agtagcaaat acagatgaaa taaaaataaa
     3721 tggaagaata taaagaagaa aaaactaaga aaataaacaa aaatgtaagt gaaagtaagc
     3781 catatgtgat ggctactgcc tgtggtcagg gcttgagaag ctgaggcagg aggattacaa
     3841 atttaaggca tctgtggttt cagagggact ttgaagccca tctggaccac agagtaagac
     3901 cggcttttgt tcttcagaga acataaacaa aagaaagtat atgataatta tggggaatag
     3961 tctcgtggat ttaaatatag acaaaaatac atttaagttt atcttttgaa gacaacaaag
     4021 agggcttgaa tggatgtgtg tggggcttaa gtcatgctgc agattggaga cagggcctga
     4081 aggaacatcg accatcactg aaatccccag gatctgggag caacaccata gctgccaagg
     4141 gtctaattta aatctgtcct actcactggt caacatattg gactctggtg ttaatataat
     4201 gttaaaatag ctgcttacat ggttaaaaga aaagaaaaga aaatgtgctg attgtttgag
     4261 atgaaagtaa aagaaaacct gctaaatcat tggggaactt gggaggaaaa tcattttaaa
     4321 taaacaaatc acatcattac acagcattat ccagtggcct gcctctttta tttttctctt
     4381 atttttgtga tcaataatca ctgtacatat agatatttag ccactttttt tagctccatc
     4441 gacttcagtg gttaggtcag tccccatcga gacaccggac ttaaagaact gagcattgat
     4501 aagaactcag tatggctgca taggagacaa gaacaagcag tgatctagtg attcacacct
     4561 gtcttgcctt tactgtattc acaggagctt tggattgaga agaattcagt caaggagcag
     4621 gaggtaggct taaggcaggc ctggataaag tatggtcctg gaagatgtcc caaagaaatt
     4681 caaagatgat tatttcttta gtttttgcct tgtcctcacc agtaattgct cccatctagg
     4741 gagagggagg gatattgatg tctctctttt aaacatatgt ttactcttcc aaggtgactt
     4801 atgggactaa gaaaggaagc aaagcttttt accaaaagta gacttaaact ttgagttttt
     4861 acgttgctgt ttatatctct aattcagcac tcttattgct gtagctaagc cttttcgatt
     4921 ctatattaag tagagttgaa agtggagatc tttcttgagt tcttagtagt ggaaatgctg
     4981 agctctccca taaaaatgat gtgcctgaat ggtttgccat atatagcctt tattatgtga
     5041 tgatatgatc cttttattct gaatttcttc aggactttta acataagggg atgttaaatt
     5101 ttgtccaaag ccattttttt ttgcatttat aaagatgatc atgttattct gtctttgagc
     5161 ccatttatgt aatttctaat acacacacac acatccctgt atctggaata aagccaatgt
     5221 agttgtggtg aaaaa
//
