LOCUS       NM_026515               2387 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus PCNA clamp associated factor (Pclaf), mRNA.
ACCESSION   NM_026515 XM_918050 XM_925450
VERSION     NM_026515.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2387)
  AUTHORS   Kim,B., Huang,Y., Ko,K.P., Zhang,S., Zou,G., Zhang,J., Kim,M.J.,
            Little,D., Ellis,L.V., Paschini,M., Jun,S., Park,K.S., Chen,J.,
            Kim,C. and Park,J.I.
  TITLE     PCLAF-DREAM drives alveolar cell plasticity for lung regeneration
  JOURNAL   Nat Commun 15 (1), 9169 (2024)
   PUBMED   39448571
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2387)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2387)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2387)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2387)
  AUTHORS   Karg,E., Smets,M., Ryan,J., Forne,I., Qin,W., Mulholland,C.B.,
            Kalideris,G., Imhof,A., Bultmann,S. and Leonhardt,H.
  TITLE     Ubiquitome Analysis Reveals PCNA-Associated Factor 15 (PAF15) as a
            Specific Ubiquitination Target of UHRF1 in Embryonic Stem Cells
  JOURNAL   J Mol Biol 429 (24), 3814-3824 (2017)
   PUBMED   29055779
  REMARK    GeneRIF: UHRF1 ubiquitinates PAF15 at Lys 15 and Lys 24 and
            promotes its binding to PCNA during late S-phase
REFERENCE   6  (bases 1 to 2387)
  AUTHORS   Turchi,L., Fareh,M., Aberdam,E., Kitajima,S., Simpson,F.,
            Wicking,C., Aberdam,D. and Virolle,T.
  TITLE     ATF3 and p15PAF are novel gatekeepers of genomic integrity upon UV
            stress
  JOURNAL   Cell Death Differ 16 (5), 728-737 (2009)
   PUBMED   19219066
REFERENCE   7  (bases 1 to 2387)
  AUTHORS   van Bueren,K.L., Bennetts,J.S., Fowles,L.F., Berkman,J.L.,
            Simpson,F. and Wicking,C.
  TITLE     Murine embryonic expression of the gene for the UV-responsive
            protein p15(PAF)
  JOURNAL   Gene Expr Patterns 7 (1-2), 47-50 (2007)
   PUBMED   16815099
  REMARK    GeneRIF: highly restricted expression of the p15(PAF) gene in a
            spatio-temporal manner during embryogenesis
REFERENCE   8  (bases 1 to 2387)
  AUTHORS   Simpson,F., Lammerts van Bueren,K., Butterfield,N., Bennetts,J.S.,
            Bowles,J., Adolphe,C., Simms,L.A., Young,J., Walsh,M.D.,
            Leggett,B., Fowles,L.F. and Wicking,C.
  TITLE     The PCNA-associated factor KIAA0101/p15(PAF) binds the potential
            tumor suppressor product p33ING1b
  JOURNAL   Exp Cell Res 312 (1), 73-85 (2006)
   PUBMED   16288740
REFERENCE   9  (bases 1 to 2387)
  AUTHORS   Powles,N., Babbs,C., Ficker,M., Schimmang,T. and Maconochie,M.
  TITLE     Identification and analysis of genes from the mouse otic vesicle
            and their association with developmental subprocesses through in
            situ hybridization
  JOURNAL   Dev Biol 268 (1), 24-38 (2004)
   PUBMED   15031102
REFERENCE   10 (bases 1 to 2387)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK011090.1, AK011835.1 and AC112676.8.
            
            On or before Dec 7, 2005 this sequence version replaced
            XM_925450.1, XM_918050.1, NM_026515.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK013105.1, AK011835.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                AK011090.1         7-46
            41-881              AK011835.1         1-841
            882-2387            AC112676.8         1621-3126
FEATURES             Location/Qualifiers
     source          1..2387
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 35.58 cM"
     gene            1..2387
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
                     /note="PCNA clamp associated factor"
                     /db_xref="GeneID:68026"
                     /db_xref="MGI:MGI:1915276"
     exon            1..152
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..439
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
                     /note="p15PAF; HCV NS5A-transactivated protein 9 homolog;
                     PCNA-associated factor of 15 kDa"
                     /codon_start=1
                     /product="PCNA-associated factor"
                     /protein_id="NP_080791.2"
                     /db_xref="CCDS:CCDS23299.1"
                     /db_xref="GeneID:68026"
                     /db_xref="MGI:MGI:1915276"
                     /translation="MVRTKANYVPGAYRKAVASQAPRKVLGSSTFVTNSSSSSRKAEN
                     KYAGGNPVCVRPTPKWQKGIGEFFRLSPKESKKENQAPEEAGTSGLGKAKRKACPLQP
                     DHRDDENE"
     exon            153..230
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
                     /inference="alignment:Splign:2.1.0"
     exon            231..393
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
                     /inference="alignment:Splign:2.1.0"
     exon            394..2387
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
                     /inference="alignment:Splign:2.1.0"
     regulatory      935..940
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
                     /note="hexamer: ATTAAA"
     polyA_site      958
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
                     /note="major polyA site"
     regulatory      1991..1996
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
                     /note="hexamer: AATAAA"
     polyA_site      2013
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
     regulatory      2082..2087
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
                     /note="hexamer: ATTAAA"
     polyA_site      2105
                     /gene="Pclaf"
                     /gene_synonym="2810417H13Rik; mKIAA0101; Ns5apt9; Ns5atp9;
                     p15(PAF); Paf; PAF15"
ORIGIN      
        1 aaagagaccc atttaaacgg tggcgggaac atcattttcg ggttcttctc taattgagac
       61 atctgcagtt ggggtgacgg tgaaagttgt ctcttcttgt gtgaacatgg tgcggaccaa
      121 agcaaactac gttccaggag cctacagaaa agcggtggct tctcaagccc ctaggaaggt
      181 gcttggctcc tccacctttg tcaccaattc ttcaagttcg tcgagaaaag ctgaaaataa
      241 gtatgcagga gggaacccag tctgtgtgcg cccaactccc aagtggcaaa aaggcatcgg
      301 ggaattcttc aggctgtccc ctaaagagtc taaaaaggaa aaccaggctc ctgaagaagc
      361 aggaaccagt ggcttaggaa aagcaaagag aaaagcttgt cctttgcaac ctgatcacag
      421 agatgatgaa aacgaataga atttactcat ctgaataatg tctccggttt ttctacatta
      481 cttacatgta aatttgggta aatgagtttg tccaattggc ttgttgaggg gaaaaaaaat
      541 taggctaaaa tttagccatt caaaagaaac cagatgtaag aatggagaat ttttataatt
      601 tgtaaatttg aattgcatgc ttacacttat gccctatgct cctcctttct tacctgttaa
      661 agcttcttct taaagccaac gttccctggc actctacttg ctactctacg gtctttgctt
      721 agatttttgt actgatgcca ttttatgggc agtgattatg gaaatgacgc catattgtta
      781 tggcatgttt gctttaaaaa tttgacttag gctgggtgtg gtggcgcacg cctttaatct
      841 ttaagagtga gttccaggtc agccagggct atacagagaa accctgtctc gaaaaaccaa
      901 aaaaaaaaaa aaaaattgac ttagtctttt ttacattaaa attttcaata ttacctaagt
      961 aaaatctctt gtcatttatc agaatgggtt ggggaggcaa agataaaatg ctgaaaagct
     1021 agttgtgtat ctttttaagg aaatgttagc tgggtgttaa agggctgcac acctttggtc
     1081 tcagcactga ggaggcaaag ccaggtggat ccctgagtct caggctatag agggagttcc
     1141 agccagccag gactaggact atacagagga tctctgtctt gaaaaaacaa aaagaaagaa
     1201 aagagttaaa agaccagttt gtcttgagga cttaactagt tgacaaccat acaaagagat
     1261 aaaatactaa cagaagcagg gacaaagact ccatagatac attaaaagga tttttttgga
     1321 tatacattca gttcgttatc ataaaacagt actttttttc atgtactact ttttctttcc
     1381 tatgtacccc ctgacagctc ctctgttagc ccggcttgtc ttggaactca cttggcagtc
     1441 aggctgaggt gggattcaag gtgggcacca ccacgccctt agataaaata atgagacaaa
     1501 tcgtgctgca aatcaggttt tatatgtcag gtccttagca tttccccgtc atttctcaag
     1561 atgacttgag atcattgaac ttatagatat agtagtaact gttttgagat aggatctcat
     1621 tatatagcct cttaggtggc cttatgtaga acacgctaac cttgaattca cagagatctg
     1681 cctatctgtc tatcatctgc taggattata ggtgggaaca tgcattttta ctttttattt
     1741 tgttatattt atctcatttt cgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgcttgta
     1801 tgcacacgaa attgtgtgtt tgggtatgtg tggaggctca aggatgctat tgaatctcct
     1861 gtattcacaa cacaaggaac catgggtatg tcaaccaggg tagcctcaaa cttcctcttt
     1921 tttttttttt ttttgtaatc ctactgtctc agtctccctg ggtgctgggg ttaacggtgt
     1981 gtacccccat aataaatgat atacttgact ttctcctcat ggtttgacag actatcactt
     2041 tttcaaaatt aaccatgttt ttggcagcct atctttttta cattaaaatt ttcaatatta
     2101 cctaagtaaa atctcttgtc atttatcaga atgggttggg gaggcaaaga taaaatgctg
     2161 aaaagctagt tgtgtatctt tttaagggtt tctctgtgta gccctggctg tcctggaact
     2221 cactctgtag accaggctgg cctcaaactc agaaatccaa ctgcttagac attaagcaga
     2281 acctctttca atccaaagta ctttgaaaat catgtttctt gtttctctgt tttttgtttg
     2341 tgcttttgcc tttttaaata aacatttatt tttattttgc atacatg
//
