LOCUS       NM_172716               7681 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus polycomb group ring finger 3 (Pcgf3), transcript
            variant 1, mRNA.
ACCESSION   NM_172716
VERSION     NM_172716.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7681)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7681)
  AUTHORS   Cho,K.W., Andrade,M., Bae,S., Kim,S., Eyun Kim,J., Jang,E.Y.,
            Lee,S., Husain,A., Sutliff,R.L., Calvert,J.W., Park,C. and
            Yoon,Y.S.
  TITLE     Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation
            Through Modulation of the TARDBP/RBM38 Axis
  JOURNAL   Circulation 147 (24), 1823-1842 (2023)
   PUBMED   37158107
REFERENCE   3  (bases 1 to 7681)
  AUTHORS   Kanki,Y., Muramatsu,M., Miyamura,Y., Kikuchi,K., Higashijima,Y.,
            Nakaki,R., Suehiro,J.I., Sasaki,Y., Kubota,Y., Koseki,H.,
            Morioka,H., Kodama,T., Nakao,M., Kurotaki,D., Aburatani,H. and
            Minami,T.
  TITLE     Bivalent-histone-marked immediate-early gene regulation is vital
            for VEGF-responsive angiogenesis
  JOURNAL   Cell Rep 38 (6), 110332 (2022)
   PUBMED   35139389
REFERENCE   4  (bases 1 to 7681)
  AUTHORS   Liu,S., Aldinger,K.A., Cheng,C.V., Kiyama,T., Dave,M.,
            McNamara,H.K., Zhao,W., Stafford,J.M., Descostes,N., Lee,P.,
            Caraffi,S.G., Ivanovski,I., Errichiello,E., Zweier,C., Zuffardi,O.,
            Schneider,M., Papavasiliou,A.S., Perry,M.S., Humberson,J.,
            Cho,M.T., Weber,A., Swale,A., Badea,T.C., Mao,C.A., Garavelli,L.,
            Dobyns,W.B. and Reinberg,D.
  TITLE     NRF1 association with AUTS2-Polycomb mediates specific gene
            activation in the brain
  JOURNAL   Mol Cell 81 (22), 4663-4676 (2021)
   PUBMED   34637754
  REMARK    Erratum:[Mol Cell. 2021 Nov 18;81(22):4757. doi:
            10.1016/j.molcel.2021.10.023.. PMID: 34798045]
REFERENCE   5  (bases 1 to 7681)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7681)
  AUTHORS   Almeida,M., Pintacuda,G., Masui,O., Koseki,Y., Gdula,M., Cerase,A.,
            Brown,D., Mould,A., Innocent,C., Nakayama,M., Schermelleh,L.,
            Nesterova,T.B., Koseki,H. and Brockdorff,N.
  TITLE     PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome
            inactivation
  JOURNAL   Science 356 (6342), 1081-1084 (2017)
   PUBMED   28596365
  REMARK    GeneRIF: Authors conclude that RYBP/YAF2 binding to H2AK119u1
            likely underpins the transient interaction of noncanonical PRC1
            complexes with Xist RNA domains but does not account for stable
            interaction of PCGF3/5-PRC1 complexes.
REFERENCE   7  (bases 1 to 7681)
  AUTHORS   Zhao,W., Tong,H., Huang,Y., Yan,Y., Teng,H., Xia,Y., Jiang,Q. and
            Qin,J.
  TITLE     Essential Role for Polycomb Group Protein Pcgf6 in Embryonic Stem
            Cell Maintenance and a Noncanonical Polycomb Repressive Complex 1
            (PRC1) Integrity
  JOURNAL   J Biol Chem 292 (7), 2773-2784 (2017)
   PUBMED   28049731
REFERENCE   8  (bases 1 to 7681)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 7681)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   10 (bases 1 to 7681)
  AUTHORS   Powles,N., Babbs,C., Ficker,M., Schimmang,T. and Maconochie,M.
  TITLE     Identification and analysis of genes from the mouse otic vesicle
            and their association with developmental subprocesses through in
            situ hybridization
  JOURNAL   Dev Biol 268 (1), 24-38 (2004)
   PUBMED   15031102
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158912.3 and AC133896.7.
            
            On Dec 6, 2019 this sequence version replaced NM_172716.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK089091.1, AK085574.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-193               AC158912.3         11884-12076         c
            194-233             AC158912.3         1224-1263           c
            234-374             AC158912.3         818-958             c
            375-492             AC133896.7         42582-42699
            493-589             AC133896.7         43903-43999
            590-645             AC133896.7         47096-47151
            646-753             AC133896.7         54933-55040
            754-842             AC133896.7         56629-56717
            843-980             AC133896.7         64627-64764
            981-1061            AC133896.7         68420-68500
            1062-7681           AC133896.7         69150-75769
FEATURES             Location/Qualifiers
     source          1..7681
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 53.13 cM"
     gene            1..7681
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /note="polycomb group ring finger 3"
                     /db_xref="GeneID:69587"
                     /db_xref="MGI:MGI:1916837"
     exon            1..193
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /inference="alignment:Splign:2.1.0"
     exon            194..233
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /inference="alignment:Splign:2.1.0"
     exon            234..374
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /inference="alignment:Splign:2.1.0"
     exon            375..492
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /inference="alignment:Splign:2.1.0"
     CDS             384..1109
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /note="isoform 1 is encoded by transcript variant 1; ring
                     finger protein 3; polycomb group RING finger protein 3;
                     RING finger protein 3A"
                     /codon_start=1
                     /product="polycomb group RING finger protein 3 isoform 1"
                     /protein_id="NP_766304.2"
                     /db_xref="CCDS:CCDS19512.1"
                     /db_xref="GeneID:69587"
                     /db_xref="MGI:MGI:1916837"
                     /translation="MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVK
                     YLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGM
                     EVPGDIKGEACSAKQHLDPRNGETKADDNSNKETAEEKQEEDNDYHRSDEQVSICLEC
                     NSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFV
                     VVTRWRFKKAPLLLHYRPKMDLL"
     exon            493..589
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /inference="alignment:Splign:2.1.0"
     exon            590..645
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /inference="alignment:Splign:2.1.0"
     exon            646..753
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /inference="alignment:Splign:2.1.0"
     exon            754..842
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /inference="alignment:Splign:2.1.0"
     exon            843..980
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1061
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..7681
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5032..5037
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /note="hexamer: AATAAA"
     regulatory      5043..5048
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /note="hexamer: AAGAAA"
     polyA_site      5055
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /note="major polyA site"
     polyA_site      5061
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /note="major polyA site"
     regulatory      7656..7661
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
                     /note="hexamer: AATAAA"
     polyA_site      7681
                     /gene="Pcgf3"
                     /gene_synonym="2310035N15Rik; D630042K08Rik; DONG1;
                     E430039C14; Rnf3; RNF3A"
ORIGIN      
        1 acacactgcg catgctccag ccgcggcgcc cccgactccg cactcggctg ggttcgggca
       61 tttccgcctc tttgttttaa actctgcacg gcttttttct cctcctcttg ggggggaccc
      121 agagggagcg gcgccccctc cccctcccgg cgagcccccg cgtgcgcccg ctcgcccgcc
      181 gcccgagacg cagacttcac aatgtagccc cgattccaga ctgtcattca cagaaaatgg
      241 aaaaggaaca agggacagaa ggaaggtgca gaagccagcc agaactcaga gtgaggaggg
      301 atcatcgcat ccacttggtg gcctgaagcc tccatgccac cgagtgagga aggacacgca
      361 gacatccaga ggagaagcca aagatgttga ccaggaagat taaactctgg gatataaatg
      421 cccacatcac ctgccgcctg tgcagcggct acctcattga cgcaaccaca gtgactgagt
      481 gtttgcacac attctgcagg agctgcctgg tgaagtatct ggaggagaat aatacctgcc
      541 ccacctgcag gatcgtgatc catcagagcc acccattaca gtatatcggt catgacagaa
      601 ccatgcagga cattgtttac aagctggtgc caggcctcca ggaagcggaa atgaggaaac
      661 agagggaatt ctatcacaaa ctgggcatgg aggtaccagg tgacatcaag ggggaggcgt
      721 gctcagcaaa acagcactta gatccccgaa atggtgaaac caaagcagac gacaattcaa
      781 ataaagagac agcagaggag aagcaggagg aggacaatga ctaccacagg agtgacgagc
      841 aggtaagcat ctgtctggaa tgcaacagca gcaaactacg tggcctcaag cggaagtgga
      901 tcagatgctc agcccaagca actgtgctgc acctgaaaaa atttatcgcc aagaagctta
      961 acctctcctc ctttaatgag ctggacattt tatgcaatga ggagatcctg ggcaaggacc
     1021 acactctcaa gttcgtggtt gttacaagat ggagattcaa gaaggcaccc ctcctgctac
     1081 actacagacc caagatggac ttgctgtaag ttcagccaga ctcagcccac acccagcact
     1141 ctacatggca aaatgtgctg tggaacgttg cctctgggtg ccatgcggac cagatttctg
     1201 aatagagaat atttataact tttgtatgag agaatccact cccaacaaga cactaccagc
     1261 acgcgtttac agaggatgaa aacacttcgc agtttgctcg tctctgcttc aggtccacag
     1321 gccagagaag aagtgaaaca ttagcacgtc ccacaccacg tctgacacgc agcacctctg
     1381 cttgctttcc agggcttgag aatcttgagt ttcagtttag ttcatggatt aggtttcata
     1441 ataagcctca aaaatatttg tactttaagt cctttgtaag ttattgaaag tcttttcatg
     1501 gtaaatattt atgttgcttt tagcttcctg aagacttaag agatatataa aattttaatt
     1561 taaagtatac ccaaagaggc ttgcagcaat gctatgactt agccgcggtg tttaatttct
     1621 agggtactca gaagcccatc cccgaggttg agtctgagac tgtgcatcct gagatggcct
     1681 gtgttggttg ggcaagacaa gaacccttcc atcactcccc agtgtcatgt ggctgtaatc
     1741 tggctccccc agtaaggcaa actagaggtg gtgtggccag tgcagcactg gcttgttgaa
     1801 aagttcttgg aaagacagtt ttccttagag aggccatcac tgaagctcct gccttttcca
     1861 ttctgttttc cttctgctgg aaaaatgtag tggtggctgt gtttgtcact taccaaccag
     1921 cacatgccat ccagtgggga gactttataa agacacttag gaggtagcct ctagcctcca
     1981 tgttcctggt agatcatggg gttaacatgc gttctttggg tctttttcat gaaaggtaac
     2041 tgagcgacct gctcacttga ggaaacagct cgcttcagca gaagtggctt tttcagtcat
     2101 agagaggata gtatttgtta acacacacac ctttctcaca tacaatttat tgctttgtta
     2161 ggttagagaa tgaataagac actagcatat ccaacttcat tccctctgca ggggtatgag
     2221 ggcaagagta aggagaacgg gtcctgacct ggggtcccag ggacctctca gcctgggtgc
     2281 ccttccaggt ccagtgagaa ttgtaggatc ctataatccc agcagtacct ctgctcttgg
     2341 tgagcatatg agatcttagt gtatccctgg gggtcaggct ttctgagtct tcaccttagc
     2401 aactggaata ttttcttgag tttgctttga cagttggaat tgagtttatc aacacccact
     2461 ttttcttcta cttcctcttt cacatacaca gtgtcagaag cagcgattag tgagacttaa
     2521 tgttggtaag taagaaaaaa aacatccaaa ttaactcaat ctttaatgtc tgaccttcta
     2581 aaacaaaagc aagctctttt tgttttgaat taatcaaaat tcacctttct atgtaagcca
     2641 gtttggatta ttcagtttcc tgagtttgct gtccattcaa atcatttcta gagttactat
     2701 acaagggttt atgcgtaaat attacctttc tacctcagaa cacacgtgct gctgaagcat
     2761 tctgcaagac cgtgttctca caatgcagtt acattagaac ttaggtattt tcccatgtgg
     2821 tgaaattaag cagttacaaa cctccaaatt caagtaaagt taatttacag atcagatcaa
     2881 acttagtatg gctgtataat ctcatgatat atatttgtaa ctttgtagct acttttagaa
     2941 tcacttgact ctgctatggt gctaagttga tagatctaag tattcagcga ggtggacatt
     3001 gcaaccgatg tcttagctgg gcgccaccgc cccaacagcc ctgcttctgt caccacgtta
     3061 acctgttaaa cctcagcagc aaaataccta tttttctaag attccatccc cgcctgtgtg
     3121 cactgcagac ggtctcctga tgcccttctg ccctttggtc tgacctgtag ccttacctcg
     3181 ctcagagatg aagcagagtg agctggcgtc cgatggaagc ttccgggcgc cttatttcac
     3241 tcctgccaag ctccacgtga catccaaggc cgaattttat ttttccagca tgaacactag
     3301 gatcagttag cgattggtcc tgtcaagctt tctcagcagg cggagctcct gcgaagttgt
     3361 tttcatagct gccgatgcta gaaatcgggt gcggccggcc ggcagctctg agaccagcct
     3421 cccagcacgt ggtctcgctc aacaccattt tcacaaaaat agaaaactca gatagaatat
     3481 ataatattga atttaagatt tggggggtta aaaaaaagaa aacttaactt tataaaatta
     3541 tttattctat tttaagcctt ctatcatatt ttcccatcca attgtttggt ttccgtggtc
     3601 cagctttatt tacaggcata taagataaaa ttgtgagatg ttttgcaagc ttcttttact
     3661 ttttgtagcc tttggtttgt atgtttttat agggatgaag aggcattttt atgcttttgt
     3721 gcaataggtt ccaacatgcg tttattagtg tttaaattgt gatctagcat ctactaaatt
     3781 gaaagggaat ataggtggaa tttcaaaatc tgtgcgttca gctatttggt tttgcctttt
     3841 tcactgttat tataagaatg ctgttaccgg gattatgtgc gtgcaagagt gagtgtgtgt
     3901 gtgtttgcgt gtgtgtgtgt ttgcgtttgt gtgtgtgtgt gtgtgtacgt actttctatc
     3961 aatattaaaa gataaacagc caggcaggaa gtgacgaggt tagcaccatc ttaggcttgc
     4021 atctctgtgg gtgcacccaa gtcctcgagc taaatctgtg actaagccac cctgggtgtt
     4081 ggggtttcac tgtccccacc tggtagtgct accctccact ggcctgcagc tcctgacacc
     4141 tgccctggcc agcagagact tggaggctgg tgtgtttcct ttctaagggc atacagggtg
     4201 gtgtattaca gtgctctgaa atgtatcatt agatttaatg ttccagtaat gagccaactg
     4261 agttctactt tgtatatgga tatgttccta aaacattgac agtaaattga gtgcagatag
     4321 tgaaattccc acacacacac ctacacacac acacacacac acacacacac acacaacaca
     4381 cgtgtctgtt tcctcaggaa atcatttaag ccccaacaca tcacatgtga ccttaacatg
     4441 aaaacaaaag ttttctctgc cttgatatta aatacactaa gtaaataaac tgagatgcgt
     4501 agattaggaa atcacttaat tgtaccacag tctgcatatc tttgcattcc tgcaggcagg
     4561 gattagacca tggtctcaca cccagtgttc ctgttgtcat ttacttccat ccaagagcac
     4621 atttggagaa agaactaagg tgtgcctgtg agatggaact gaggtgtgcc tgtgtgtcac
     4681 tttagccagt gactcacact cactgtttag ttccagctct caacttgtgc cagacacggt
     4741 tttcccaagc gaaggtaaca tcaggttacg gacagcagcg ccacctgagc tctcacgctg
     4801 gagcgcagcc acagctagca acggtcacgg tgtatgaaat gctgcagata cagagttttt
     4861 gactgtttaa tttgaaagtt tacatttttt atgattgcgt tagtgtgtaa tttttgtacc
     4921 atcagtggct agtttttgtc taaaatcttt tttggaatat tgcttaatgt tttgatttta
     4981 tgatagtgaa gcttgtattc agtgttttgc caattaatat tatatgcttg taataaaagc
     5041 agaagaaaaa cttaactaaa atctcccagt ctggcaatgt ttttacctaa ggtatatgtt
     5101 aagagtttga cagataatgt gttacagaac atgatcagcc ccctccagct tccaggctca
     5161 gccatctggg gatagaaagt atccaggaaa accaaccaac caaccaaaat cctccaaaca
     5221 aggttttgtt tgttttattt ttctgttcat agtccctaac tatagtataa taattgcttc
     5281 tatagcattt gctttgtttt cattggtttt ggtttttgag attgagtctc tgtgtagtct
     5341 tgatatcttg gaactcactt tgtagaccag acaagcctta aactctagat ctgcctgact
     5401 ctgcctcctg agtgctggga tgaaaggtgt atgccaccat gtttggccac actgtataat
     5461 ttactataag tcatctagag ataatttcaa aggattcagg aatggtgtac tattaaaaaa
     5521 aaaaaaaagc tgttttatta aagggcttga gcatcctcag attctgatgt ctacaggaga
     5581 tctgacctca aggacactaa ggagcctgtg cagtgaactg ctctagatgc tctccactga
     5641 gtcaggcctc actctctcag gaacacatgc ccactgtgtc acagtcatgg aagtgggtgg
     5701 agtggggggt gcctgctgga aaaaccccct tatcaacccc atccccacct aacactagca
     5761 tttcctctta agtttgatct ctggaagcag ccttccccca cgcccctttg tggcttaaaa
     5821 gaatacctgg actttcagac aggatagcaa taaattcaca gttacagaaa gcccacattt
     5881 ccccaagaca aaagaagttg tttctcttga ggtcttcctg aagttttgtc tgttctttgg
     5941 gcagaggctg tgtgtggctc atgcttttgt tgtatgtgag tatgtagaaa aatccactga
     6001 tttccatact gaatctggca ggcattttct ggatttccgt ggaaacctct aagccctggc
     6061 tgaagagcag gagtgagcaa gatagcaagt aggttgtaga gtctcagagt tcgtgattga
     6121 aagattttgt tttaagcatg attcaggttg tagtgttttg ataaatacta tttgccaagt
     6181 caagaacttc tttcctgata ctgcttataa aaaagtatga tcagaaattt gtactattga
     6241 gcaaaaaaca aaaacaaaca aacaaacccc acaaaattaa caattttgct tttttatttg
     6301 aacatttaac atgtacagat ttatatgaac ttcactctaa tcaaaaggca gtgagtacct
     6361 caaggaactc tttaatgcaa accaactgtt gtagctggac tttggctact ttgtggttct
     6421 tctttcttcc accctttcaa ctcactaaca ctagatagga gagggaaaag gataaggggg
     6481 gcaactatat cattatacta cttcctgctg actagaggca cttcttgggg caagtttgct
     6541 gtcagcatat ctaatttctt ctttttgtct cttcacacat gactacttga caaactgcag
     6601 ccaacaacat ctagtcacca actggccaac cgaccagcag ctcctctccg ggtatttgca
     6661 tatcatctga aaagtcccca gaaatccata catcacacac tggaagaaac tatccgcagc
     6721 tggcaaaatc acaaccctgc tagagcacaa ggcaaatcac agctgctgtg ggcagtctga
     6781 agcagcccca tactccacac ctgagattaa aacgaagact attcttataa tagttatgtg
     6841 tttctaaaga aaccaaagtt ctcaccgcac acttatcaca tcctaagtta tattgttgag
     6901 aagtcattaa tagaattggc catatataat cttcacaatt gtattgagta tctttgagat
     6961 tcatcctgtt gattgcgtca gtactccttg tttaaatact gaatattatt tccctgtgtg
     7021 aacaaaacag tttacttgta atgtgatgat acattttatt tcagttgttt taattgtttt
     7081 taggtttatc ttatgtgtat gagtgtttta tttgcatgtg tgtgaggtgc ccacagaggc
     7141 cagaagaagg cactggatgc ccctacaagt ggagttgctg agaactgagc ctgggtcctc
     7201 tgcaagagca gccagtattc ttcttaacca ctgagccatc gctctctggc ttccagagca
     7261 tcatttttgc ccatttaaca tatggctttg tcttgtatgc aatgtctgtg catatccctc
     7321 ccaccttcga gttacttttt gggggagaga gcaagttgag actaggtttc actagggtta
     7381 gagttagggt taagagccct ggctgtccta gaactcactt tatagaccag gctgtccttg
     7441 aacttggaga tctgcctgcc tctacctccc caagtcctgg gattaaaggc ctgtgccacc
     7501 actacccggt gagttacttg ttttcttaac tactgagttt taagaaatct ttgcattttc
     7561 tgaagccagt tgggtaagtg atttgctaat attattttct cctcatctct acttgtcttc
     7621 cccccaccct tgacttttct aatagatctt tctctaataa agtcacattt ataagaacat
     7681 a
//
