LOCUS       NM_053145               3382 bp    mRNA    linear   ROD 08-AUG-2023
DEFINITION  Mus musculus protocadherin beta 20 (Pcdhb20), mRNA.
ACCESSION   NM_053145
VERSION     NM_053145.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3382)
  AUTHORS   Mancia Leon WR, Spatazza J, Rakela B, Chatterjee A, Pande V,
            Maniatis T, Hasenstaub AR, Stryker MP and Alvarez-Buylla A.
  TITLE     Clustered gamma-protocadherins regulate cortical interneuron
            programmed cell death
  JOURNAL   Elife 9, e55374 (2020)
   PUBMED   32633719
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3382)
  AUTHORS   Elbert A, Vogt D, Watson A, Levy M, Jiang Y, Brule E, Rowland ME,
            Rubenstein J and Berube NG.
  TITLE     CTCF Governs the Identity and Migration of MGE-Derived Cortical
            Interneurons
  JOURNAL   J Neurosci 39 (1), 177-192 (2019)
   PUBMED   30377227
REFERENCE   3  (bases 1 to 3382)
  AUTHORS   Remeseiro S, Cuadrado A, Kawauchi S, Calof AL, Lander AD and Losada
            A.
  TITLE     Reduction of Nipbl impairs cohesin loading locally and affects
            transcription but not cohesion-dependent functions in a mouse model
            of Cornelia de Lange Syndrome
  JOURNAL   Biochim Biophys Acta 1832 (12), 2097-2102 (2013)
   PUBMED   23920377
REFERENCE   4  (bases 1 to 3382)
  AUTHORS   Remeseiro S, Cuadrado A, Gomez-Lopez G, Pisano DG and Losada A.
  TITLE     A unique role of cohesin-SA1 in gene regulation and development
  JOURNAL   EMBO J 31 (9), 2090-2102 (2012)
   PUBMED   22415368
REFERENCE   5  (bases 1 to 3382)
  AUTHORS   Vanhalst K, Kools P, Vanden Eynde E and van Roy F.
  TITLE     The human and murine protocadherin-beta one-exon gene families show
            high evolutionary conservation, despite the difference in gene
            number
  JOURNAL   FEBS Lett 495 (1-2), 120-125 (2001)
   PUBMED   11322959
REFERENCE   6  (bases 1 to 3382)
  AUTHORS   Wu Q, Zhang T, Cheng JF, Kim Y, Grimwood J, Schmutz J, Dickson M,
            Noonan JP, Zhang MQ, Myers RM and Maniatis T.
  TITLE     Comparative DNA sequence analysis of mouse and human protocadherin
            gene clusters
  JOURNAL   Genome Res 11 (3), 389-404 (2001)
   PUBMED   11230163
REFERENCE   7  (bases 1 to 3382)
  AUTHORS   Wu Q and Maniatis T.
  TITLE     Large exons encoding multiple ectodomains are a characteristic
            feature of protocadherin genes
  JOURNAL   Proc Natl Acad Sci U S A 97 (7), 3124-3129 (2000)
   PUBMED   10716726
REFERENCE   8  (bases 1 to 3382)
  AUTHORS   Wu Q and Maniatis T.
  TITLE     A striking organization of a large family of human neural
            cadherin-like cell adhesion genes
  JOURNAL   Cell 97 (6), 779-790 (1999)
   PUBMED   10380929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC020967.2.
            
            On Feb 17, 2023 this sequence version replaced NM_053145.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC031895.1, AF326313.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3382              AC020967.2         113545-116926
FEATURES             Location/Qualifiers
     source          1..3382
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 19.51 cM"
     gene            1..3382
                     /gene="Pcdhb20"
                     /gene_synonym="Pcdhb14; PcdhbT"
                     /note="protocadherin beta 20"
                     /db_xref="GeneID:93891"
                     /db_xref="MGI:MGI:2136758"
     exon            1..3382
                     /gene="Pcdhb20"
                     /gene_synonym="Pcdhb14; PcdhbT"
                     /inference="alignment:Splign:2.1.0"
     CDS             145..2544
                     /gene="Pcdhb20"
                     /gene_synonym="Pcdhb14; PcdhbT"
                     /codon_start=1
                     /product="protocadherin beta-14 precursor"
                     /protein_id="NP_444375.2"
                     /db_xref="CCDS:CCDS57120.1"
                     /db_xref="GeneID:93891"
                     /db_xref="MGI:MGI:2136758"
                     /translation="MGRRRALILQKRQVLVFFVFLGLSQASAESLRYSVAEETEIGSF
                     VANLAKDLGLGVAELSSREARVVSDDNKKHLLLNLLTGDMLLNERLDREELCGSTQPC
                     VLPFQVVLENPLQFYRAELHVRDINDHSPTFLDKEITIKISESTTIGATFLIENAQDL
                     DIGSNSLQDYSISPSSYFYVKIHDSGDGKIYPELVLDKALDHEEESELRLTLTALDGG
                     SPPRSGTTLIVIKVLDINDNAPEFAQSFYEVQVPEDMPIGSSITAISAKDLDMGIYGK
                     ISYSFLHASEDIRKTFEINPTSGEVNLRSLMDFEVIQSYSVNIQATDGGGLSAKCTLS
                     VKVLDINDNAPEVIMSSVTKAIPENASETLVALFSVRDQDSGDNGRILCSIQDDLPFI
                     LKPSFKNFFTLLSEKALDRERRAEYNITITASDMGTPRLTTQHTIRVQVSDINDNAPA
                     FTQTSYTMFIYENNSPALHIGTISATDKDSGSNAHITYSLLPAQDPELALASLISINA
                     DNGQLFALRALDYEVLQAFEFQVGATDRGSPALSSQTLVRVVVLDDNDNAPFVLYPMQ
                     NASAPCTELLPRVAEPGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEV
                     RTTRLLSERDVPKHRLVLLVKDNGDPPRSASVTLHVLVVDGFSQPYLPLPEVARDPAQ
                     EEDVLTLYLVIALASVSSLFLLSVLLFVGVRLCRRARAASLGGCSVPEGHFPGHLVDV
                     TGTGTLSQNYQYEVCFTGGTGTNEFKFLRPVMPSLQLHDPDSNMLEKENFRNSLGFNI
                     Q"
ORIGIN      
        1 agacgattcc atgagaagag aggtattaca ggagcttcac cggcagagct gccaagggac
       61 tttcaataga aatatcggac ctttacctgt aaaatttggg actgggttta aattttggag
      121 taaaagaagt cacctgaagg aaccatggga aggagaaggg ctctcatcct gcagaaaagg
      181 caagtcttgg ttttctttgt tttcctggga ttgtctcagg cgagtgctga atctttgcgc
      241 tattctgtag cagaggaaac agaaattggc tcttttgtgg ctaatctggc aaaggattta
      301 ggactggggg ttgcggagct gtcctccagg gaggccaggg tagtgtcaga tgataataaa
      361 aagcatttac tccttaattt gctgactgga gatatgctcc tgaatgagcg actggatcgt
      421 gaagagctat gtggctccac ccagccctgt gtgctgccct ttcaggtggt actggaaaac
      481 cccttacagt tctatcgagc tgagctgcac gtcagagata taaatgatca ctcccctaca
      541 ttcctagaca aggaaataac tattaaaata tcagaaagca ctactatcgg agccacattc
      601 ttaattgaga atgcacaaga tctggacata ggaagcaaca gtcttcagga ctacagcatt
      661 agccccagtt cttatttcta tgttaaaatt catgacagtg gcgatggaaa gatatacccg
      721 gagctggttc tggacaaagc tttagatcat gaggaggaat ctgagcttag attgacactt
      781 acagcattag atggtgggtc tccacccagg tctgggacaa cactgattgt cataaaagtc
      841 ttggacatca acgataatgc tccagagttc gctcagagtt tctatgaggt gcaggtccca
      901 gaggacatgc ctattggctc cagtattact gccatctctg ctaaagattt agatatggga
      961 atttatggga aaatttcata ttcatttttg catgcatcag aagatattag aaaaaccttt
     1021 gaaatcaacc caacatctgg ggaagtcaat ttgagatcac taatggattt tgaagtaata
     1081 cagtcctatt ctgtaaatat ccaagcaaca gatggtggag gtctttctgc aaaatgcact
     1141 ctttcggtta aagtattaga tataaatgac aatgcaccag aagtgatcat gtcgtcggtt
     1201 acaaaggcaa ttccagaaaa tgcttcagag accctggtcg ctctattcag tgtccgagat
     1261 caagactctg gagacaacgg aaggatcctt tgctctattc aggatgacct tccatttatt
     1321 ctgaaaccaa gcttcaagaa ttttttcact ctactttctg aaaaagcact agacagagaa
     1381 aggagagctg agtacaacat caccatcact gcctccgaca tgggcacacc caggctcaca
     1441 acccagcaca ccataagagt acaggtatct gacatcaatg acaatgcccc ggccttcacc
     1501 caaacctcct acaccatgtt catctacgag aacaacagcc ctgccctgca cataggcacc
     1561 atcagtgcca cagacaaaga ctcaggctcc aatgcccaca tcacctactc gctgctaccg
     1621 gctcaggacc cagagctggc cctcgcctcg ctcatctcca ttaacgctga caacgggcag
     1681 ctatttgcgc tcagggcgct ggactatgag gtcctgcagg ccttcgagtt ccaagtgggt
     1741 gcgacagacc gaggctcgcc cgcactcagc agccagactc tggtgcgcgt ggtagtgctg
     1801 gacgacaatg acaatgcgcc cttcgtgctc tacccgatgc agaacgcctc tgcgccttgc
     1861 actgagctgc tgcccagggt ggcagaacct ggctacctgg tcaccaaagt agtggctgtg
     1921 gatcgcgact ctggccagaa tgcctggctg tcgttccagc tgctcaaggc tacagagcca
     1981 gggctgttca gcgtgtgggc gcacaatggc gaggtacgca ctaccaggct gctgagcgag
     2041 cgcgatgtgc ccaagcacag gctggtactg ctagtcaagg acaatggcga tcctccgcgc
     2101 tctgccagcg tcacgctgca cgtgctagtg gtggatggct tctctcagcc ctacctgcct
     2161 ctgccagagg tggcgcgcga ccctgcacaa gaagaagatg tactaacact ctacctggtc
     2221 atagccttgg catctgtgtc ttctctcttc ctcttgtctg tgctgctgtt tgtgggggtg
     2281 aggctgtgca ggagggccag ggctgcctct ctgggtggct gctctgtgcc tgagggacac
     2341 tttcctggcc atctggtgga cgttactggc actggaaccc tgtcccagaa ctaccaatat
     2401 gaggtgtgtt tcacaggagg tactggaacg aatgagttca aattccttag gccggtcatg
     2461 cccagtcttc agctccatga ccctgattct aatatgctgg aaaaggagaa ctttcgcaat
     2521 agccttggtt ttaatattca ataaaatttt cctttaaact taatattttc tattaacaaa
     2581 ttgcaaatgc ttgttttact taatctgtat tgaatttaag gttttactga tgatgcatgc
     2641 atttttgttt cacgtgtttt tctcacaatt actttgaaaa tctttactgg gtttatagtg
     2701 atgcaaagaa actatctgca cgttttgttt tgtttatttt gccgaggtgt tatgttaacg
     2761 gttctgctgt ttcttatata agacacagca atggaaatgc tgatttaagt atttagagtc
     2821 gatgtgttga gctgctgact aatataatac tgggtggagt ccataagcag gcagccccgg
     2881 atggatctac aacaaaagac atggagggag ggaaggaagg aaataaaaag ggacaagtgt
     2941 tatcatatat gggagtttcc ccagcatgct actaacagag agtctaaatg ttgttgtacc
     3001 tgggtagaaa ctgtactgga tcatttgtag tattctctgt tagattattt gatcagaaaa
     3061 aaaaatacta tttaaatgct tcccttccat attcagtaga agaagccttt gttttataat
     3121 gttttcaaga attaatttct tagtaagttt tccttctctg ttttctaatg atgctttcta
     3181 actattaaaa tattctaggt catgatattg ctgctttgtt gtctttaaat ccacatgttt
     3241 tcttgactaa aatttgtggt actctatacc acttattgct aaagcagata atcttgtctt
     3301 aagtaaaata gtcttgtacc agaaaacaac aggataaaac cttactagga tttaaaataa
     3361 agataaagat ttttaaattt aa
//
