LOCUS       NM_053142               3306 bp    mRNA    linear   ROD 08-AUG-2023
DEFINITION  Mus musculus protocadherin beta 17 (Pcdhb17), mRNA.
ACCESSION   NM_053142
VERSION     NM_053142.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3306)
  AUTHORS   Xu L, Zheng Y, Li X, Wang A, Huo D, Li Q, Wang S, Luo Z, Liu Y, Xu
            F, Wu X, Wu M and Zhou Y.
  TITLE     Abnormal neocortex arealization and Sotos-like syndrome-associated
            behavior in Setd2 mutant mice
  JOURNAL   Sci Adv 7 (1) (2021)
   PUBMED   33523829
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3306)
  AUTHORS   Mancia Leon WR, Spatazza J, Rakela B, Chatterjee A, Pande V,
            Maniatis T, Hasenstaub AR, Stryker MP and Alvarez-Buylla A.
  TITLE     Clustered gamma-protocadherins regulate cortical interneuron
            programmed cell death
  JOURNAL   Elife 9, e55374 (2020)
   PUBMED   32633719
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3306)
  AUTHORS   Elbert A, Vogt D, Watson A, Levy M, Jiang Y, Brule E, Rowland ME,
            Rubenstein J and Berube NG.
  TITLE     CTCF Governs the Identity and Migration of MGE-Derived Cortical
            Interneurons
  JOURNAL   J Neurosci 39 (1), 177-192 (2019)
   PUBMED   30377227
REFERENCE   4  (bases 1 to 3306)
  AUTHORS   Alvarez-Saavedra M, De Repentigny Y, Lagali PS, Raghu Ram EV, Yan
            K, Hashem E, Ivanochko D, Huh MS, Yang D, Mears AJ, Todd MA,
            Corcoran CP, Bassett EA, Tokarew NJ, Kokavec J, Majumder R,
            Ioshikhes I, Wallace VA, Kothary R, Meshorer E, Stopka T, Skoultchi
            AI and Picketts DJ.
  TITLE     Snf2h-mediated chromatin organization and histone H1 dynamics
            govern cerebellar morphogenesis and neural maturation
  JOURNAL   Nat Commun 5, 4181 (2014)
   PUBMED   24946904
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3306)
  AUTHORS   Remeseiro S, Cuadrado A, Kawauchi S, Calof AL, Lander AD and Losada
            A.
  TITLE     Reduction of Nipbl impairs cohesin loading locally and affects
            transcription but not cohesion-dependent functions in a mouse model
            of Cornelia de Lange Syndrome
  JOURNAL   Biochim Biophys Acta 1832 (12), 2097-2102 (2013)
   PUBMED   23920377
REFERENCE   6  (bases 1 to 3306)
  AUTHORS   Wang X, Weiner JA, Levi S, Craig AM, Bradley A and Sanes JR.
  TITLE     Gamma protocadherins are required for survival of spinal
            interneurons
  JOURNAL   Neuron 36 (5), 843-854 (2002)
   PUBMED   12467588
REFERENCE   7  (bases 1 to 3306)
  AUTHORS   Vanhalst K, Kools P, Vanden Eynde E and van Roy F.
  TITLE     The human and murine protocadherin-beta one-exon gene families show
            high evolutionary conservation, despite the difference in gene
            number
  JOURNAL   FEBS Lett 495 (1-2), 120-125 (2001)
   PUBMED   11322959
REFERENCE   8  (bases 1 to 3306)
  AUTHORS   Wu Q, Zhang T, Cheng JF, Kim Y, Grimwood J, Schmutz J, Dickson M,
            Noonan JP, Zhang MQ, Myers RM and Maniatis T.
  TITLE     Comparative DNA sequence analysis of mouse and human protocadherin
            gene clusters
  JOURNAL   Genome Res 11 (3), 389-404 (2001)
   PUBMED   11230163
REFERENCE   9  (bases 1 to 3306)
  AUTHORS   Wu Q and Maniatis T.
  TITLE     Large exons encoding multiple ectodomains are a characteristic
            feature of protocadherin genes
  JOURNAL   Proc Natl Acad Sci U S A 97 (7), 3124-3129 (2000)
   PUBMED   10716726
REFERENCE   10 (bases 1 to 3306)
  AUTHORS   Wu Q and Maniatis T.
  TITLE     A striking organization of a large family of human neural
            cadherin-like cell adhesion genes
  JOURNAL   Cell 97 (6), 779-790 (1999)
   PUBMED   10380929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC020967.2.
            
            On Feb 17, 2023 this sequence version replaced NM_053142.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC017149.1, AK122533.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3306              AC020967.2         94253-97558
FEATURES             Location/Qualifiers
     source          1..3306
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 19.5 cM"
     gene            1..3306
                     /gene="Pcdhb17"
                     /gene_synonym="mKIAA1621; Pcdhb16; PcdhbQ"
                     /note="protocadherin beta 17"
                     /db_xref="GeneID:93888"
                     /db_xref="MGI:MGI:2136754"
     exon            1..3306
                     /gene="Pcdhb17"
                     /gene_synonym="mKIAA1621; Pcdhb16; PcdhbQ"
                     /inference="alignment:Splign:2.1.0"
     CDS             173..2572
                     /gene="Pcdhb17"
                     /gene_synonym="mKIAA1621; Pcdhb16; PcdhbQ"
                     /codon_start=1
                     /product="protocadherin beta-16 precursor"
                     /protein_id="NP_444372.2"
                     /db_xref="CCDS:CCDS29183.1"
                     /db_xref="GeneID:93888"
                     /db_xref="MGI:MGI:2136754"
                     /translation="METAWMCNLRQRQVLAFFVLLHVSGAGAELGPYSIEEETERGSF
                     VANLGKDLGVDLAEISNRRARIISQENKEHLQLNLQSGDLLINEKLDREELCGPIEPC
                     VLHFQVLMENPLEVFQAELRVMDINDYSPVFSEREMILRILENSALGDTFPLNNALDS
                     DVAINNIQTYRLSSNSHFLVVTRNRSDGRKYPELVLEKELDREEEPELRLTLTALDGG
                     APPRSGTAQVLIEVVDINDNAPKFQQPTYRVQIPENSPTGSLVLTVSANDLDSGDYGK
                     VLYALSQPSEDISKTLEVNPVTGEIRLRKEVDFETIPSYEVDIKATDGGGLSGKCTLL
                     LKVVDVNDNAPEVMLSALTSPVPENSPDEVVAVFSVKDPDSANNGKMIASIEEDLPFL
                     LKSSGKNFYTLVTKRALDREEREKYNITITVSDLGTPRLTTQHTITVQVSDTNDNAPA
                     FNQTSYTLFVRENNSPAMHIGTISATDSDAGSNSHISYSLLPSHDPQLALDSLISINA
                     DNGQLFALRALDYEALQAFEFHVGAIDQGSPALSSQALVRVVVLDDNDNAPFVLYPMQ
                     NSSAPCTELLPRAAEPGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEV
                     RTTRLLSERDVPKHRLVLLVKDNGDPPRSASVTLHVLVVDGFSQPYLPLPEVARNPAH
                     DEDALTLYLVIALASVSSLFLLSVLLFVGVRLCRRARSASLSGYSVPEGHIPGHLVDV
                     RGVGTLSQSYQYDVCLMGDSSGTSEFNFLKPVFPSSLDQCSGKEIEENSSLHNSFGFH
                     H"
ORIGIN      
        1 ctcaccacct agaatcaaag ggtgtgtctt tttcggccaa agcataggcg agtgtgaaac
       61 cttagatatt ctatttggag gcttgattct cacgttctgg actgtgagat agtgctgtca
      121 cgatcctgga catatgtgaa gctactgtga agcaaacgcc gaggaaagag ccatggagac
      181 tgcatggatg tgcaatctga gacaaaggca agtcctggct ttctttgttt tgctgcatgt
      241 gtcaggggca ggggcagaac tgggccccta ttccatagag gaagaaacag agaggggctc
      301 ctttgtggca aatcttggga aagatctggg ggtggacctg gcagagatat ccaatcgcag
      361 ggctcggatc atttcccaag aaaacaaaga gcatttgcag ctcaaccttc aatctggaga
      421 tctgctcata aatgagaaac tggaccgaga ggagctatgt ggccccattg agccgtgtgt
      481 tctacacttc caagtgttaa tggaaaaccc tttagaggta tttcaggctg aactgagggt
      541 gatggacata aatgactatt ctccggtgtt cagtgaaaga gaaatgatac tgagaatact
      601 agaaaacagt gctctgggag atacatttcc tttaaataat gctctggact cagacgtagc
      661 aatcaacaat atccagacct ataggctcag ctcaaactct catttcctgg ttgtaacccg
      721 caaccgcagt gatggcagga agtacccaga gctggtgctg gagaaagaac tggatcgaga
      781 ggaggaacct gagctgaggt taactctgac agctttggat ggtggcgctc ctccccggtc
      841 tgggacggca caggttctca ttgaagtagt ggacatcaac gataatgcac ccaagtttca
      901 gcagccaaca taccgagtgc aaattcccga gaacagtccc accggttctc tggtactcac
      961 agtctcagcc aatgacttgg acagtggaga ttatggaaaa gtattgtatg cactttctca
     1021 gccttcagaa gatattagca aaacgttaga agtaaaccct gtaaccgggg agattcggct
     1081 acgaaaagag gtggattttg aaactattcc ctcttatgaa gtggatatca aggccacgga
     1141 tgggggaggt ctctcaggaa aatgcacgct gttactgaag gtggtggacg tgaatgacaa
     1201 tgccccagaa gtgatgctat ctgctcttac cagcccagtc ccagaaaact ccccggacga
     1261 ggtagttgct gttttcagtg ttaaagatcc tgattcagcg aacaatggaa aaatgattgc
     1321 ctccatcgaa gaagatcttc cctttcttct aaaatcttca gggaagaact tttacacttt
     1381 agtgaccaag agagcacttg acagggaaga aagagagaaa tacaacatca ccatcactgt
     1441 ctctgacctg ggcacaccca ggctcacaac ccagcacacc ataacagtgc aggtctctga
     1501 caccaatgac aacgcccccg ccttcaacca aacctcatac accctgttcg tccgcgagaa
     1561 caacagcccc gccatgcaca taggcaccat cagtgccaca gactctgacg ctggctccaa
     1621 ttcccacatc agctactcgc tgttgccttc ccacgacccg cagctggccc tggactcgct
     1681 catctccatc aacgcagaca atgggcagct gttcgcgctc agggcgctgg actatgaggc
     1741 cctgcaggcc tttgagttcc acgtgggtgc aatagaccaa ggctcacctg cgctcagcag
     1801 ccaagcgctg gtgcgcgtgg tggtgctgga cgacaatgac aatgcgccct tcgtgctcta
     1861 cccgatgcag aactcctctg cgccttgcac agaactgctg cccagggcgg cggaacccgg
     1921 atacctggtc accaaggtgg tggctgtgga tcgcgactct ggccagaatg cctggctgtc
     1981 attccaactt ctcaaggcta cggagcccgg gctgttcagc gtgtgggcgc acaatggcga
     2041 ggtacgcact accagactgc tgagcgagcg cgatgtgccc aagcacaggc tggtcctgct
     2101 ggtcaaggac aatggcgatc ctccgcgctc tgccagcgtc acgctgcacg tgctagtggt
     2161 ggatggcttc tctcagccct acctgcctct gccagaggtg gcgcgcaatc ccgcgcacga
     2221 tgaggacgct ctaacactgt atctggtcat agccttggca tctgtgtctt ctctcttcct
     2281 cttgtctgtg ctgctgtttg tgggggtgag gctgtgcagg agggccaggt cggcctctct
     2341 gagtggttat tccgtgcctg agggccacat tcctggccat ctggtggatg tcagaggtgt
     2401 ggggaccctg tcccagagct accagtatga tgtatgtctg atgggcgatt cttctgggac
     2461 cagtgagttt aacttcttaa agccagtttt ccctagctct ctagaccagt gctctggtaa
     2521 agaaatagag gaaaattcct cactccacaa tagttttgga tttcatcatt aacagaaagc
     2581 ttcttaacag tatttacttc ccaatattgt tgttgattag ctaatgtctg ttcacctgtg
     2641 actagcaaca attttaattt tcactttgcc tgtccttttt caggctcgga cctcatgttt
     2701 ggttttactc atatttgtag cacaggattt ttcataggct ctcagaaaac caaaaggttt
     2761 tctctgcagt taatgcattc gctgaaactt ttctagcact ttgtttttct tcctcacttg
     2821 ctctccatgt tttatgttcc tagacttctt gaattattaa aatactgtgt tgcatgctat
     2881 atacatacat aatagttggt atttctgcat ttcctttcta tactgccaga cttggtgatt
     2941 agccaccttt gatttttgtt atatatatat aatagttgtc ttaagttatg ctagtatttt
     3001 atagctttat ttttctttgt ttatatatct tgatttaaaa attaatttct gtcataagtg
     3061 atacaagtat ctagtgaacc tggaaataag aatagtattg taagatattg agttggtgta
     3121 catgtgccta aatttgtgaa aatcgaggta atttgggcat tagaaggtat caaatagaag
     3181 tatataaatt tttcttttaa ttctgcatga aagcctagaa attgacgttg agttttcaat
     3241 ggcttacaat ctagtcacac tcttttgaat aatcttttga ataaacaatg tatatttatc
     3301 atcata
//
