LOCUS       NM_053140               2795 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus protocadherin beta 15 (Pcdhb15), mRNA.
ACCESSION   NM_053140
VERSION     NM_053140.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2795)
  AUTHORS   Mancia Leon WR, Spatazza J, Rakela B, Chatterjee A, Pande V,
            Maniatis T, Hasenstaub AR, Stryker MP and Alvarez-Buylla A.
  TITLE     Clustered gamma-protocadherins regulate cortical interneuron
            programmed cell death
  JOURNAL   Elife 9, e55374 (2020)
   PUBMED   32633719
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2795)
  AUTHORS   Alvarez-Saavedra M, Yan K, De Repentigny Y, Hashem LE, Chaudary N,
            Sarwar S, Yang D, Ioshikhes I, Kothary R, Hirayama T, Yagi T and
            Picketts DJ.
  TITLE     Snf2h Drives Chromatin Remodeling to Prime Upper Layer Cortical
            Neuron Development
  JOURNAL   Front Mol Neurosci 12, 243 (2019)
   PUBMED   31680852
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2795)
  AUTHORS   Elbert A, Vogt D, Watson A, Levy M, Jiang Y, Brule E, Rowland ME,
            Rubenstein J and Berube NG.
  TITLE     CTCF Governs the Identity and Migration of MGE-Derived Cortical
            Interneurons
  JOURNAL   J Neurosci 39 (1), 177-192 (2019)
   PUBMED   30377227
REFERENCE   4  (bases 1 to 2795)
  AUTHORS   Hirano K, Kaneko R, Izawa T, Kawaguchi M, Kitsukawa T and Yagi T.
  TITLE     Single-neuron diversity generated by Protocadherin-beta cluster in
            mouse central and peripheral nervous systems
  JOURNAL   Front Mol Neurosci 5, 90 (2012)
   PUBMED   22969705
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2795)
  AUTHORS   Dallosso AR, Hancock AL, Szemes M, Moorwood K, Chilukamarri L, Tsai
            HH, Sarkar A, Barasch J, Vuononvirta R, Jones C, Pritchard-Jones K,
            Royer-Pokora B, Lee SB, Owen C, Malik S, Feng Y, Frank M, Ward A,
            Brown KW and Malik K.
  TITLE     Frequent long-range epigenetic silencing of protocadherin gene
            clusters on chromosome 5q31 in Wilms' tumor
  JOURNAL   PLoS Genet 5 (11), e1000745 (2009)
   PUBMED   19956686
  REMARK    Erratum:[PLoS Genet. 2009 Dec;5(12). doi:
            10.1371/annotation/012d5a44-8239-4057-8c3b-3dc159ea3a02]
REFERENCE   6  (bases 1 to 2795)
  AUTHORS   Vanhalst K, Kools P, Vanden Eynde E and van Roy F.
  TITLE     The human and murine protocadherin-beta one-exon gene families show
            high evolutionary conservation, despite the difference in gene
            number
  JOURNAL   FEBS Lett 495 (1-2), 120-125 (2001)
   PUBMED   11322959
REFERENCE   7  (bases 1 to 2795)
  AUTHORS   Wu Q, Zhang T, Cheng JF, Kim Y, Grimwood J, Schmutz J, Dickson M,
            Noonan JP, Zhang MQ, Myers RM and Maniatis T.
  TITLE     Comparative DNA sequence analysis of mouse and human protocadherin
            gene clusters
  JOURNAL   Genome Res 11 (3), 389-404 (2001)
   PUBMED   11230163
REFERENCE   8  (bases 1 to 2795)
  AUTHORS   Wu Q and Maniatis T.
  TITLE     Large exons encoding multiple ectodomains are a characteristic
            feature of protocadherin genes
  JOURNAL   Proc Natl Acad Sci U S A 97 (7), 3124-3129 (2000)
   PUBMED   10716726
REFERENCE   9  (bases 1 to 2795)
  AUTHORS   Wu Q and Maniatis T.
  TITLE     A striking organization of a large family of human neural
            cadherin-like cell adhesion genes
  JOURNAL   Cell 97 (6), 779-790 (1999)
   PUBMED   10380929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK038663.1.
            
            On Jun 6, 2007 this sequence version replaced NM_053140.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK038663.1, BC066178.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: downstream AUG is associated
                                                with N-terminal localization
                                                signal
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2795              AK038663.1         3-2797
FEATURES             Location/Qualifiers
     source          1..2795
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 19.5 cM"
     gene            1..2795
                     /gene="Pcdhb15"
                     /gene_synonym="Pcdhb7; PcdhbO"
                     /note="protocadherin beta 15"
                     /db_xref="GeneID:93886"
                     /db_xref="MGI:MGI:2136750"
     exon            1..2795
                     /gene="Pcdhb15"
                     /gene_synonym="Pcdhb7; PcdhbO"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..2532
                     /gene="Pcdhb15"
                     /gene_synonym="Pcdhb7; PcdhbO"
                     /codon_start=1
                     /product="protocadherin beta-7"
                     /protein_id="NP_444370.1"
                     /db_xref="CCDS:CCDS29181.1"
                     /db_xref="GeneID:93886"
                     /db_xref="MGI:MGI:2136750"
                     /translation="MEARLEQAVQKRQVLFLYVFLGASWASAEQLQYSVAEETERGTF
                     LANLAKDLGLGLGELSAREARIVSDQNTRFLLLSPLTGELILNEKLDREELCGPTEPC
                     VLTFQLLLERPFQIYRAALHIKDINDNSPVFLDKEILLKISESTTPGATLLLERAQDA
                     DVGTNSLSNYTISPNDYFHIHVHDGGEGPIIPELVLDKMLDREEIPEFTLTLTALDGG
                     SPPRSGTALVQILVLDINDNSPQFVQSLYKVQSPENTPVGSLVVAVSARDLDTGSYGQ
                     IDYTFFYATERILQTFQINSTSGELYLKRELNYEAIQTYSITIQARDGGGLSGKCAVV
                     VEVMDVNDNPPEFLLSSLNSPIPENSQETVVAVFKIRDRDSGNNGKTLCSIANDLPFV
                     LKPSVENFYTLVTEKPLDRESNTEYNITITVTDMGIPRLTTQHTITVQVSDINDNAPT
                     FTQTSYTMFVRENNSPALHIGTISATDSDSGSNAHITYSLRLPHDPQLALDSLISINA
                     DNGQLFALRALDYEALQAFEFHVGAIDQGSPALSSQALVRVVILDDNDNAPFVLYPMQ
                     NASAPYTELLPRAAEPGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEV
                     RTTRLLSERDVPKHKLLVVVKDNGEPPRSASVTLHVLLVDGFSQPFLILPEVARDPAQ
                     EDDELTLYLVIALASVSSLFLVSVLLFVGVRLCRRARAASPGVCFVPEEHFPGHLVDV
                     SGAGTLSQNYQYEVCLTGGSGITSEFKFLSPIASNFLTESTGREIE"
ORIGIN      
        1 aggaaatgat atagctagcg gtagcaagcc ctggagaagg cacccctctc ttctcacagg
       61 aattgctagt gtccaggtca ttcctaagga ttccagctgc aggcattcca gggagctgct
      121 tgaggctaaa tggaaggaat ttggggtttt attttgaaag tcttggaaag aatggaggcc
      181 agattggaac aagctgtgca gaaaaggcaa gtactgtttc tttatgtgtt tcttggagcg
      241 tcttgggcta gcgccgaaca gcttcagtat tctgtggcag aggaaaccga gagagggact
      301 ttcctagcca atctagcaaa ggatttgggg ctggggctgg gggaactgtc agcccgggaa
      361 gctagaattg tttcagacca gaacacacga tttttactgc tcagtccgct tactggagaa
      421 ttaattctaa atgagaagct ggaccgagag gaactgtgcg gccccacaga gccctgtgtg
      481 ctgactttcc agttgctgtt ggaaagacca tttcagattt atcgcgctgc actacatatc
      541 aaagatataa atgataattc tccagtattc ctagacaaag aaatactctt gaaaatatca
      601 gaaagtacca ctccaggggc gacgcttctc ttggaaaggg cacaggatgc cgatgtggga
      661 acgaacagcc tgagtaacta caccatcagc cccaatgatt atttccatat tcacgtgcat
      721 gatggagggg aggggcctat cattcctgaa ctggtactgg ataaaatgct ggaccgggaa
      781 gaaataccag aattcacttt aactctcaca gccttagatg gtggctctcc acccagatct
      841 gggacagcct tggtgcaaat cttggtgttg gacataaatg acaactcccc tcaattcgtg
      901 cagtcacttt acaaagttca gtcacctgaa aacacccctg ttggctcctt ggttgtcgct
      961 gtgtctgcca gggacttaga cacaggaagt tacggacaaa tagactacac atttttttat
     1021 gccacagaaa gaattctcca aacgtttcaa atcaattcta catctggcga actttatctt
     1081 aaacgcgaac tcaactatga agcgattcaa acttattcga taactattca ggccagagat
     1141 ggtggtggac tttctgggaa atgtgctgtg gttgtagagg taatggacgt gaatgataac
     1201 ccacctgaat ttctcttgtc gtcacttaat agcccaattc cagaaaattc acaagagaca
     1261 gttgttgctg tatttaaaat tagagacaga gattcgggga acaatggaaa aaccctgtgc
     1321 tccattgcga atgatctccc tttcgtcctg aagccatctg tggaaaattt ctatactctg
     1381 gtaacagaga agcctttaga tagagaatca aacactgaat acaacatcac catcacagtc
     1441 accgacatgg gcatacccag gctcacaacc cagcacacca taacagtgca ggtctctgac
     1501 atcaacgaca acgcccccac cttcacccaa acctcctaca ccatgttcgt ccgcgagaac
     1561 aacagccccg ccctgcacat tggcaccatc agcgccacag actcagactc aggctccaat
     1621 gcccacatca cctactcgtt gcggctgcct cacgacccgc agctggccct ggactcgctc
     1681 atctccatca atgcagacaa tgggcaactg ttcgcgctca gggctctgga ctatgaggcc
     1741 ctgcaggcct tcgagttcca cgtgggtgca atagaccaag gctcccctgc gctcagcagt
     1801 caggctctgg tgcgcgtggt gatactggac gacaatgaca atgcgccctt cgtgctctac
     1861 ccgatgcaga acgcctctgc accctacact gagctgctgc ccagggcggc agaacccgga
     1921 tacctggtca ccaaggtggt ggcagttgac cgtgattctg gccagaacgc ctggctgtca
     1981 tttcagttgc ttaaggccac agagcccgga ctgtttagtg tgtgggcgca caatggtgag
     2041 gtgcgcacca ccaggctact aagcgagcga gatgtgccca agcataagct gctagtggtg
     2101 gtcaaggata atggagagcc tccacgctct gccagtgtca cactgcatgt gttgctggtc
     2161 gatggcttct ctcagccctt cctgattctg ccagaggtgg cgcgcgaccc tgcacaagaa
     2221 gatgatgagc taacactcta cctggtcatt gccttggctt ctgtgtcttc tctcttcctg
     2281 gtatctgtgc tgctgttcgt tggagtaaga ctctgcagga gggcccgggc agcctctccg
     2341 ggtgtctgct ttgtgcctga agaacacttt cctggccacc tggtggatgt cagcggtgca
     2401 gggaccctgt cccagaacta ccagtatgag gtgtgtctga ctggaggatc agggataacc
     2461 agtgaattta agtttctaag tccaattgcc tctaacttcc taaccgaaag cacagggaga
     2521 gaaatagaat aaaagctaaa cccttctgcc catggatgaa gctctaatgt aaactatacc
     2581 cttgttgtgt aatgaagaat gatttcatgt taacatctag aagttaacta atttaggaca
     2641 gaaaagaata cctgtattta ttcccaaaaa ccttttcttt aatttatgaa atgcatgtgt
     2701 tgtgtgctat ctcaaatcta atttgatttc tctttgtttt ttaagatttg ttgaactgca
     2761 atctattaaa caacaaatct tggtagagat tgttt
//
