LOCUS       NM_053138               3693 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus protocadherin beta 13 (Pcdhb13), mRNA.
ACCESSION   NM_053138
VERSION     NM_053138.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3693)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3693)
  AUTHORS   Mancia Leon,W.R., Spatazza,J., Rakela,B., Chatterjee,A., Pande,V.,
            Maniatis,T., Hasenstaub,A.R., Stryker,M.P. and Alvarez-Buylla,A.
  TITLE     Clustered gamma-protocadherins regulate cortical interneuron
            programmed cell death
  JOURNAL   Elife 9, e55374 (2020)
   PUBMED   32633719
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3693)
  AUTHORS   Elbert,A., Vogt,D., Watson,A., Levy,M., Jiang,Y., Brule,E.,
            Rowland,M.E., Rubenstein,J. and Berube,N.G.
  TITLE     CTCF Governs the Identity and Migration of MGE-Derived Cortical
            Interneurons
  JOURNAL   J Neurosci 39 (1), 177-192 (2019)
   PUBMED   30377227
REFERENCE   4  (bases 1 to 3693)
  AUTHORS   Junghans,D., Heidenreich,M., Hack,I., Taylor,V., Frotscher,M. and
            Kemler,R.
  TITLE     Postsynaptic and differential localization to neuronal subtypes of
            protocadherin beta16 in the mammalian central nervous system
  JOURNAL   Eur J Neurosci 27 (3), 559-571 (2008)
   PUBMED   18279309
REFERENCE   5  (bases 1 to 3693)
  AUTHORS   Vanhalst,K., Kools,P., Vanden Eynde,E. and van Roy,F.
  TITLE     The human and murine protocadherin-beta one-exon gene families show
            high evolutionary conservation, despite the difference in gene
            number
  JOURNAL   FEBS Lett 495 (1-2), 120-125 (2001)
   PUBMED   11322959
REFERENCE   6  (bases 1 to 3693)
  AUTHORS   Wu,Q., Zhang,T., Cheng,J.F., Kim,Y., Grimwood,J., Schmutz,J.,
            Dickson,M., Noonan,J.P., Zhang,M.Q., Myers,R.M. and Maniatis,T.
  TITLE     Comparative DNA sequence analysis of mouse and human protocadherin
            gene clusters
  JOURNAL   Genome Res 11 (3), 389-404 (2001)
   PUBMED   11230163
REFERENCE   7  (bases 1 to 3693)
  AUTHORS   Wu,Q. and Maniatis,T.
  TITLE     Large exons encoding multiple ectodomains are a characteristic
            feature of protocadherin genes
  JOURNAL   Proc Natl Acad Sci U S A 97 (7), 3124-3129 (2000)
   PUBMED   10716726
REFERENCE   8  (bases 1 to 3693)
  AUTHORS   Wu,Q. and Maniatis,T.
  TITLE     A striking organization of a large family of human neural
            cadherin-like cell adhesion genes
  JOURNAL   Cell 97 (6), 779-790 (1999)
   PUBMED   10380929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC020967.2, AY013774.1 and BB672005.1.
            
            On Jun 8, 2007 this sequence version replaced NM_053138.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK082435.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                AC020967.2         51783-51836
            55-2445             AY013774.1         1-2391
            2446-3659           AC020967.2         54228-55441
            3660-3693           BB672005.1         369-402
FEATURES             Location/Qualifiers
     source          1..3693
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 19.49 cM"
     gene            1..3693
                     /gene="Pcdhb13"
                     /gene_synonym="Pcdbh6; PcdhbM"
                     /note="protocadherin beta 13"
                     /db_xref="GeneID:93884"
                     /db_xref="MGI:MGI:2136748"
     exon            1..3693
                     /gene="Pcdhb13"
                     /gene_synonym="Pcdbh6; PcdhbM"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..2445
                     /gene="Pcdhb13"
                     /gene_synonym="Pcdbh6; PcdhbM"
                     /codon_start=1
                     /product="protocadherin beta-6 precursor"
                     /protein_id="NP_444368.1"
                     /db_xref="CCDS:CCDS29179.1"
                     /db_xref="GeneID:93884"
                     /db_xref="MGI:MGI:2136748"
                     /translation="MSHAKMWCKTRQVMVLITSMLLWEVGSGSIQYAMLEETESGTFV
                     ANLTKHLGLRVGELAARDARVVFKGNRQYLQLDPQTQDLMLNENLDREELCGSTEPCV
                     LSFRVLLKNPLQFYQAELRVIDINDHAPEFPAREMLLKISEIAPPGKIFPLKMAQDLD
                     TGSHSIQSYTVSDNPHFHVLTRNRSDGKKFPELVLDKALDREKQDQLRLKLTAVDGGS
                     PPRSGTTEIQILVLDINDNTPEFAQELYEVQVPENSPIGSLLITVSARDLDAGPFGEV
                     SYGLSQDDDVNEPFEINTKTGEIRLKSTLDFEAFQSYHVDVEALDGGGLTGKCSLVVQ
                     VLDVNDNAPEVILSSLNSPIPENLPGIIVAVFSVSDADSGNNQQVMCSIDDNLPFLLR
                     PSMENFYTLETDGALDRESRSEYNITITVTDMGTPRLTTQHNITVQVSDINDNAPAFT
                     QTSYTLFVHENNSPALHIGTISATDSDSGSNAHITYSLLLPQDKQLTLTSLVSINADN
                     GQLFALRALDYEALQAFEFRVDATDQGSPALSSQVLVRVVVLDDNDNAPFVLYPMQNA
                     SAPCTELLPRAAEPGYLVTKVVAVDRDSGQNAWLSFQLFKATEPGLFSVWAHNGEVRT
                     TRLLSERDVPKHRLLLLVKDNGEPPRSASVTLHVLLVDGFSQPYLPLPEVAQDSTEDA
                     EDALTLYLVIALASVSSLFLLSVVLFVGVRLCKKFRAASLGGYSVPEGHFPGHLVDVS
                     GAGTLSQSYQYEVCLRGDTGTGEFKLRKAINPHFPSVPSERNTEESPTLRNSFLFI"
ORIGIN      
        1 acctcggtga tgaagagctg gaagggattt ttcctctgga ttcagacaat agagatgtca
       61 cacgcaaaaa tgtggtgcaa gacaaggcaa gtgatggttt tgattacatc gatgcttttg
      121 tgggaggtgg gttcaggatc aattcagtat gccatgctgg aggagacaga aagtggcacg
      181 tttgtggcca acctgactaa gcacttgggg ctaagggtgg gagaactggc tgctcgggat
      241 gctagagtgg ttttcaaggg gaacagacag tatttgcagc ttgaccctca gacccaggat
      301 ttgatgctaa atgaaaacct ggaccgggag gaactgtgtg gctccacaga accttgtgtg
      361 ctgtctttcc gggtgttact aaaaaatcct ttgcagtttt atcaagctga actgagagtt
      421 atagatataa atgaccacgc cccagagttt cctgccagag aaatgctcct taaaatatca
      481 gaaatagctc cacctggaaa gatattccct ttgaaaatgg cacaggactt agacactggc
      541 agccacagca ttcagagcta cactgtcagt gataaccctc acttccacgt gctcactcgc
      601 aatcgcagcg atggcaagaa gttccctgag ctagtgttgg acaaggcttt ggaccgtgag
      661 aagcaagacc agctcagact aaagctcact gcggtggatg gtgggtctcc gcccaggtca
      721 gggaccacag aaattcaaat attagtctta gatataaatg acaacacgcc ggaatttgct
      781 caggagctct atgaggtcca agttcctgag aacagtccca ttggctcact gcttattaca
      841 gtctcagcaa gagatttaga tgcaggaccc tttggggagg tgtcttatgg actgtctcaa
      901 gatgatgatg ttaacgagcc ttttgaaata aacacaaaga caggagaaat tcgactgaaa
      961 agcacgttgg attttgaagc attccagtct taccatgtgg atgtcgaggc cctagatggt
     1021 ggcgggctaa caggaaaatg ctccttagtc gtccaagtat tggacgtgaa tgataacgct
     1081 ccagaagtga tcctatcctc actcaacagc cccatccctg aaaatttgcc aggtatcata
     1141 gtggcagtat tcagtgtttc agatgcggac tctggaaata accagcaggt tatgtgttcc
     1201 atagatgaca atcttccgtt tcttctaaga ccatctatgg agaatttcta tactctggaa
     1261 acagatgggg cactagacag agagagcaga tctgaataca atattaccat cacagtcacc
     1321 gacatgggca cacccaggct cacaacccag cacaacataa cagtgcaggt gtctgacatc
     1381 aacgacaatg cccctgcctt cacccaaacc tcctacacct tgttcgtcca cgagaacaac
     1441 agccccgccc tgcacatagg caccatcagt gccacagact cagattcagg ctccaatgcc
     1501 cacatcacct actcactgct gctgcctcag gacaagcagc tgaccctcac ctcgctggtc
     1561 tccatcaacg cagacaacgg gcaactgttt gcgctcaggg ctctggacta tgaggccctg
     1621 caggccttcg agttccgcgt agacgccaca gaccaaggtt ctccagcgct cagcagccaa
     1681 gtgctggtgc gcgtggtggt gctggacgac aatgacaatg cgcccttcgt gctctacccg
     1741 atgcagaatg cctctgcacc ctgcacagag ctgcttccca gggctgcaga gcccggatac
     1801 ctggtcacca aggtggtggc agttgaccgc gactctggcc agaatgcctg gctgtcattc
     1861 caactgttca aggccacgga gcctggactg tttagtgtgt gggcgcacaa tggcgaagtg
     1921 cgcaccacca ggctgctgag cgagcgcgat gtgcccaagc acaggctgct gctgctggtc
     1981 aaggacaatg gagaacctcc acgctctgcc agtgtcactc ttcatgtgct gctggtggat
     2041 ggcttctctc agccctacct gcctctgcca gaggtggcgc aggactccac agaggatgct
     2101 gaagatgcgc tcacgttata cctggttatt gccttagcat ctgtatcttc gctcttcctc
     2161 ttgtctgtgg tgctgtttgt gggggtgagg ctgtgcaaga agttcagagc ggcctctctc
     2221 ggtggctact ctgtgcctga gggacacttt cctggccatc tggtggatgt cagcggcgct
     2281 gggactcttt cccagagcta ccagtatgag gtgtgtctga gaggagacac tgggactggt
     2341 gagttcaaat tgcgaaaggc aattaatccc cactttcctt ctgtgccctc tgagaggaac
     2401 acagaggaaa gtcctactct tcggaatagc ttcttattca tctaaatact ttagtaagct
     2461 agtaaattct gtttaagctt agaaatatct tttaacctat atctgcacgc tatcgatgtg
     2521 cattgacaga agtttatgct cttacttttt atgatagcgc ctgggaatgg aatccagtgt
     2581 ctcatgcatg ttaggcaaac taaaccactg agttaaatca cttttctttt cctttctttt
     2641 cttttctttc ctttcctttt cttttctctg cttttctttc ttttctgtgt tttggaaaca
     2701 gggatgtttc tttttctttt ttctttctct tgcttattta tttacattcc gaattttgcc
     2761 cccttcctgg ttcaccctcc aagagttctt cactccatcc cccttctctt ttgcctctga
     2821 gaggatgctc ccccaccctc ccaccccctc attcacccac tcacctccac ctcacatccc
     2881 tctttccttg gggcatcctg gctgccctgg aactcactct gtagaccagg ctggccttga
     2941 actcatatcg atcccctgcc tctgtcttct gggtggtgga agtaaaagca tatgcccacc
     3001 acaggtttca ctgtgtagcc tgagatggtc tgaatctcac tagattgacc tggctgtctt
     3061 ggaactcaga gagacccacc tgcatctgtc accttagtac tgtgactaaa ggcttttgcc
     3121 gtcacacttg gcctgtctgt accattgcta ttattcttga gattttactt tttagaaaga
     3181 cagtttctgg agattccact agtttctcta ctatgcttca tagtttgttt tttaattagt
     3241 ggaactaacc tgtatttgac aagttaaata aaaatatttt aatagtatat gaactcaaac
     3301 aatcttttaa gtatactatc atgcaaagtc tttgagattc cgttttacac aagttattaa
     3361 attaatttta ctattagatt gaagaatttt taaatgtgaa cacttgatat tactgaattt
     3421 tgtaaattta gtctcatttt gtggtaactg gttatcaggt acatctttta atataaatgt
     3481 aaggaactct aaatgctaag acatatacct tacttatgta tgcacaatta ggaatgtctc
     3541 tgtgcattct aataatcaac acatatttct taaatgtaga ttttactgaa ctgtcaattc
     3601 attaaattat agtttgtgaa cattgtgtaa gaagagtatg atctttgagc atcaagatat
     3661 ttacaaaagt tgaataaatc tttgcttaat att
//
