LOCUS       NM_053136               3615 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus protocadherin beta 11 (Pcdhb11), mRNA.
ACCESSION   NM_053136
VERSION     NM_053136.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3615)
  AUTHORS   Mancia Leon WR, Spatazza J, Rakela B, Chatterjee A, Pande V,
            Maniatis T, Hasenstaub AR, Stryker MP and Alvarez-Buylla A.
  TITLE     Clustered gamma-protocadherins regulate cortical interneuron
            programmed cell death
  JOURNAL   Elife 9, e55374 (2020)
   PUBMED   32633719
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3615)
  AUTHORS   Elbert A, Vogt D, Watson A, Levy M, Jiang Y, Brule E, Rowland ME,
            Rubenstein J and Berube NG.
  TITLE     CTCF Governs the Identity and Migration of MGE-Derived Cortical
            Interneurons
  JOURNAL   J Neurosci 39 (1), 177-192 (2019)
   PUBMED   30377227
REFERENCE   3  (bases 1 to 3615)
  AUTHORS   Junghans D, Heidenreich M, Hack I, Taylor V, Frotscher M and Kemler
            R.
  TITLE     Postsynaptic and differential localization to neuronal subtypes of
            protocadherin beta16 in the mammalian central nervous system
  JOURNAL   Eur J Neurosci 27 (3), 559-571 (2008)
   PUBMED   18279309
REFERENCE   4  (bases 1 to 3615)
  AUTHORS   Vanhalst K, Kools P, Vanden Eynde E and van Roy F.
  TITLE     The human and murine protocadherin-beta one-exon gene families show
            high evolutionary conservation, despite the difference in gene
            number
  JOURNAL   FEBS Lett 495 (1-2), 120-125 (2001)
   PUBMED   11322959
REFERENCE   5  (bases 1 to 3615)
  AUTHORS   Wu Q, Zhang T, Cheng JF, Kim Y, Grimwood J, Schmutz J, Dickson M,
            Noonan JP, Zhang MQ, Myers RM and Maniatis T.
  TITLE     Comparative DNA sequence analysis of mouse and human protocadherin
            gene clusters
  JOURNAL   Genome Res 11 (3), 389-404 (2001)
   PUBMED   11230163
REFERENCE   6  (bases 1 to 3615)
  AUTHORS   Wu Q and Maniatis T.
  TITLE     Large exons encoding multiple ectodomains are a characteristic
            feature of protocadherin genes
  JOURNAL   Proc Natl Acad Sci U S A 97 (7), 3124-3129 (2000)
   PUBMED   10716726
REFERENCE   7  (bases 1 to 3615)
  AUTHORS   Wu Q and Maniatis T.
  TITLE     A striking organization of a large family of human neural
            cadherin-like cell adhesion genes
  JOURNAL   Cell 97 (6), 779-790 (1999)
   PUBMED   10380929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ058028.1, AK160803.1 and AK078189.1.
            
            On Jun 11, 2007 this sequence version replaced NM_053136.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK160803.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-411               CJ058028.1         2-412
            412-2037            AK160803.1         381-2006
            2038-3310           AK078189.1         2039-3311
            3311-3615           AK160803.1         3281-3585
FEATURES             Location/Qualifiers
     source          1..3615
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 19.49 cM"
     gene            1..3615
                     /gene="Pcdhb11"
                     /gene_synonym="Pcdhb5E; PcdhbK"
                     /note="protocadherin beta 11"
                     /db_xref="GeneID:93882"
                     /db_xref="MGI:MGI:2136746"
     exon            1..3615
                     /gene="Pcdhb11"
                     /gene_synonym="Pcdhb5E; PcdhbK"
                     /inference="alignment:Splign:2.1.0"
     CDS             202..2595
                     /gene="Pcdhb11"
                     /gene_synonym="Pcdhb5E; PcdhbK"
                     /codon_start=1
                     /product="protocadherin beta 11 precursor"
                     /protein_id="NP_444366.3"
                     /db_xref="CCDS:CCDS29178.1"
                     /db_xref="GeneID:93882"
                     /db_xref="MGI:MGI:2136746"
                     /translation="METALAKMPEQRQVFFLTILLLLWKSGSGATRYSMPEEKESGYL
                     VANVAKDLGLRVGELATRGAQIHYKGNKELLQMDAETGNLFLKEKLDREALCGATEPC
                     VLHFQVILENPVQFFQTELQLTDINDHSPEFPDREMLLKIPENAQPGTVFPLKAAQDS
                     DIGSNAVQNYTVSPNIHFHVITHSRSDGRKYPELVLDRALDREEQPELTLILTALDGG
                     APPRSGTTIVHIEVVDINDNAPQFIQSLYEVQILENSPIDTLVVTVSARDLDSGIYGN
                     VAYSLFQGDGLSQPFVIDEVTGEIRLSKELDFEGISHYNIEIAATDGGDLLGKCTVVI
                     QVLDVNDNAPELMIRKLTVPVPENSAETVVAVFSVSDSDSGDNGRIVCSIQNNIPFLL
                     KPTFENYYTLVTEGPLDRESRAEYNITITVWDLGTPRLTTQHTITVQVSDINDNAPAF
                     TQTSYTLFVQENNSPALQIGTISATDSDSGSNAHITYSLLLPQDPQLALASLISINPD
                     NGQLFVLRALDYESLQAFEFRVGATDQGSPALSSQTLVRVVVLDDNDNAPFVLYPMQN
                     ASAPCTELLPREAESGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEVR
                     TTRLLSERDVPKHRLLLLVKDNGEPQLSASVTLQVLLVNSFSQPYLSLPEVAQDPIQE
                     DGEMLTLYLVIALASVSSLFLLSVLMFVGMRLCRRAREASLGVCSVPEGHFPGHLMDV
                     SGTGTLSHSYQYDVCLSGDSRTGEFKFLKPMIPNVMVQEAGREVKENPPCRDSFVFS"
ORIGIN      
        1 agacacccag gaagccatct cattaagtcg agacagaacg atggcagctg cttgaagaag
       61 aaggtaataa gttagggttt atagaagaat ctaagaagac ggcgtcttcc tagtcggatt
      121 tactccaata tctccgcgga cactcagcag tggactgtaa tcaaccagaa gcagcagcac
      181 cctctggact gaatctgcac aatggagaca gcgctagcaa aaatgccaga gcaaaggcaa
      241 gtcttttttc ttactatctt gttgctgttg tggaagtctg gctctggggc aactagatat
      301 tccatgccag aagaaaagga gagtggctat ttggtggcaa acgtggcaaa agatctgggg
      361 ctcagggttg gagaactggc cactagagga gctcaaatcc attacaaagg aaacaaagag
      421 ctcttgcaga tggatgcaga gactgggaat ttgttcttaa aggaaaaact agaccgggag
      481 gcactgtgtg gggcgacaga accctgtgtg ctgcacttcc aggtcatact ggaaaaccct
      541 gtgcagttct tccaaactga actgcagctc actgatataa acgaccactc tccagagttc
      601 cctgacaggg aaatgcttct aaaaatccct gagaacgccc agccaggaac tgtgtttcct
      661 ctgaaggcag cccaggactc tgacataggg agcaatgccg ttcagaacta cacagtcagt
      721 cccaacatcc atttccacgt cattactcac agtcgctcag atggcaggaa atacccagag
      781 ctggtgctgg acagagccct ggacagggag gagcagcctg agctcacttt aatcctcacc
      841 gctctggatg ggggtgctcc gcctcggtca ggaaccacta tagttcacat tgaagtcgtg
      901 gacatcaatg ataacgcccc ccagtttata cagtcactct atgaggtgca gattctcgaa
      961 aatagcccca ttgatacctt agttgttaca gtctctgcca gggatttaga ttctgggata
     1021 tatggcaatg tagcctattc tctgtttcag ggtgatggat tatctcaacc atttgtaata
     1081 gatgaagtca caggagaaat ccgtcttagc aaagagctgg atttcgaggg aattagccat
     1141 tataacatag aaatcgcagc cactgatggg ggagaccttt taggaaaatg cactgtggtt
     1201 atacaggtgt tggatgtgaa tgacaacgct ccagagttga tgatcaggaa gctcacagtc
     1261 cctgtcccgg aaaattccgc cgagactgta gttgctgttt ttagtgtttc tgattctgat
     1321 tcgggggaca acggaaggat agtgtgttct atccagaaca atattccatt tctcctgaaa
     1381 cccacgtttg agaattacta caccttagtg accgaggggc cacttgatag agagagcaga
     1441 gctgagtaca atatcaccat cactgtctgg gatttgggca cacccaggct cacaacccag
     1501 cacaccataa cagtgcaggt gtctgacatc aacgacaacg cccctgcctt cacacaaacc
     1561 tcctataccc tgtttgtgca agagaacaac agtcccgccc tgcagatagg caccatcagc
     1621 gccacagact cagactcagg ctccaatgcc cacatcacct actcgctgct gctgccccaa
     1681 gacccacagc tggcccttgc ctcgctaatc tccattaacc ccgacaacgg gcagctgttc
     1741 gtactcaggg cactggacta tgaatccctg caggccttcg agttccgcgt aggcgccaca
     1801 gaccaaggct ctcctgcact cagcagccag actctggtgc gcgtggtggt gctggatgac
     1861 aatgacaatg cgcccttcgt gctctacccg atgcagaacg cctctgcgcc ttgcacagag
     1921 ctgctgccca gggaggcgga gtctggctac ctggtcacca aggtggtggc tgtggatcgc
     1981 gactctggcc agaatgcttg gctgtcgttc cagttgctca aggccacgga gcccgggctg
     2041 ttcagcgtgt gggcgcacaa tggcgaggtg cgcaccacca ggctgctgag cgagcgcgat
     2101 gtgcccaagc acaggctgct gctgctggtc aaggacaatg gcgagcctca gctctctgcc
     2161 agtgtcacac ttcaagtgct actggtgaat agtttttctc agccctacct ttctctgcct
     2221 gaggtggcac aggaccccat tcaggaggat ggagagatgc tcactctgta cctggtcatt
     2281 gccttggctt ccgtgtcttc gctcttcctc ttgtctgtcc ttatgtttgt gggaatgagg
     2341 ttgtgcagga gggccaggga ggcttctctg ggtgtctgct ctgtgcctga gggccacttc
     2401 cctggccacc tgatggatgt tagcggaact gggactctgt cccacagcta tcagtatgat
     2461 gtgtgtctat caggagactc taggactggt gagtttaaat tcctcaaacc catgattccc
     2521 aatgtaatgg tccaggaggc tgggagagaa gtgaaggaaa atcccccctg cagggatagc
     2581 tttgtattca gttaactgtt gtatttgttt cggtgaattt gtttttggca aatctattgc
     2641 aataaggatc ttctaggaaa gtgaatcatt ttctgagtac tgacactgta atcaaagttt
     2701 ctagggctaa ggtgtttgca tctttttcac ttcatgtttt gctattgata tcaaatgtaa
     2761 gaactcttat atgctaacta tacattctat tagtgagctt cactcccagc tgaaatccct
     2821 tttactctga gtatctatga ccatatttgt cttctgaact ataagccatc actgaattaa
     2881 gatatttgag ttgtgaactt tttattctta taagaaccat atatgctata ggttatctgc
     2941 attattttgc tcaccacata tctatcccat tggtctatga attatattaa aatttaaaat
     3001 ctcatttgta aacattaaag aggaaacata taatttttca tctctgtcac taaataaagg
     3061 tgttaagact ctaagagtat aatcagtggt agatcatgca tgtctgccag gcatttccaa
     3121 gtaacaaaaa gatacaagca atccaacata gtcaaattct attaaataat tgcttgacac
     3181 aatcttgttt taaaaactaa tctgaataac ataattaagt tcctccaaag aatcaagact
     3241 taattgtctc attttattga acaatcattt tttgtttatc cttgtatttc agaaataaaa
     3301 gtgtaaatgt agcttttgtg ggtcttgtgt taatctcagt tgtcaacttg agatctagaa
     3361 cttctgggca cacctacgat gcatcatctt gcttagttaa ctgaggcggg aagttcagcc
     3421 atggaagacc attgtgggta gcataggatc cctgtgctgg gatcctggac tgtatgaagt
     3481 gttactatga gcacaagtgt tcattgcttt cttcttcttg cttgagatgc agtgttacca
     3541 gttgcttcaa gctcctgtac tgcaccttac ctaccatgat gtaattttga actgagagcc
     3601 aaaacagacc tttcc
//
