LOCUS       NM_001174154            4622 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus protocadherin alpha 4B (Pcdha4b), mRNA.
ACCESSION   NM_001174154
VERSION     NM_001174154.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4622)
  AUTHORS   Wang,X., Su,H. and Bradley,A.
  TITLE     Molecular mechanisms governing Pcdh-gamma gene expression: evidence
            for a multiple promoter and cis-alternative splicing model
  JOURNAL   Genes Dev 16 (15), 1890-1905 (2002)
   PUBMED   12154121
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC020968.3, AF464175.1 and AC129315.3.
            
            On Jul 30, 2014 this sequence version replaced NM_001174154.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN02415138
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 12936, 93717
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2289              AC020968.3         164173-166461
            2290-2594           AF464175.1         1-305
            2595-2651           AC129315.3         33611-33667
            2652-4622           AC129315.3         40217-42187
FEATURES             Location/Qualifiers
     source          1..4622
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18"
     gene            1..4622
                     /gene="Pcdha4b"
                     /gene_synonym="Cnr1; Gm37013; Pcdha4; Pcdha4-g"
                     /note="protocadherin alpha 4B"
                     /db_xref="GeneID:100384868"
                     /db_xref="MGI:MGI:5610241"
     exon            1..2503
                     /gene="Pcdha4b"
                     /gene_synonym="Cnr1; Gm37013; Pcdha4; Pcdha4-g"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..2878
                     /gene="Pcdha4b"
                     /gene_synonym="Cnr1; Gm37013; Pcdha4; Pcdha4-g"
                     /note="protocadherin alpha 4-gamma; Protocadherin alpha-4;
                     PCDH-alpha-4"
                     /codon_start=1
                     /product="protocadherin alpha 4-gamma precursor"
                     /protein_id="NP_001167625.1"
                     /db_xref="GeneID:100384868"
                     /db_xref="MGI:MGI:5610241"
                     /translation="MEFSWGSGQESQRLLLSFLLLAIWEAGNSQIHYSIPEEAKHGTF
                     VGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAEC
                     SIHLEVIVDRPLQVFHVEVEVRDINDNPPRFPTTQKNLFIAESRPLDTWFPLEGASDA
                     DIGINAVLTYRLSPNDYFSLEKPSNDERVKGLGLVLRKSLDREETPEIILVLTVTDGG
                     KPELTGSVQLLITVLDANDNAPVFDRSLYTVKLPENVPNGTLVVKVNASDLDEGVNGD
                     IMYSFSTDISPNVKYKFHIDPVSGEIIVKGYIDFEECKSYEILIEGIDKGQLPLSGHC
                     KVIVQVEDINDNVPELEFKSLSLPIRENSPVGTVIALISVSDRDTGVNGQVTCSLTSH
                     VPFKLVSTFKNYYSLVLDSALDRETTADYKVVVTARDGGSPSLWATASVSVEVADVND
                     NAPVFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYV
                     SVHAESGKVFALQPLDHEELELLRFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLL
                     EPEAGVSGGIVSRLVSRSVGAGHVVAKVRAVDADSGYNAWLSYELQSSEGNSRSLFRV
                     GLYTGEISTTRILDEADSPRQRLLVLVKDHGDPAMIVTATVLVSLVENGPVPKAPSRV
                     STSVTHSEASLVDVNVYLIIAICAVSSLLVLTLLLYTALRCSTVPSESVCGPPKPVMV
                     CSSAVGSWSYSQQRRQRVCSGEYPPKTDLMAFSPSLSDSRDREDQLQSAEDSSGKQAP
                     PNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGG
                     AGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSG
                     KKEKK"
     exon            2504..2562
                     /gene="Pcdha4b"
                     /gene_synonym="Cnr1; Gm37013; Pcdha4; Pcdha4-g"
                     /inference="alignment:Splign:2.1.0"
     exon            2563..2651
                     /gene="Pcdha4b"
                     /gene_synonym="Cnr1; Gm37013; Pcdha4; Pcdha4-g"
                     /inference="alignment:Splign:2.1.0"
     exon            2652..4622
                     /gene="Pcdha4b"
                     /gene_synonym="Cnr1; Gm37013; Pcdha4; Pcdha4-g"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4598..4603
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pcdha4b"
                     /gene_synonym="Cnr1; Gm37013; Pcdha4; Pcdha4-g"
                     /note="hexamer: AATAAA"
     polyA_site      4622
                     /gene="Pcdha4b"
                     /gene_synonym="Cnr1; Gm37013; Pcdha4; Pcdha4-g"
                     /note="major polyA site"
ORIGIN      
        1 gtatttgcta gtccgaatcg gaacaatggc ggatgcagtg gcgatggact aacggattag
       61 aagaattctc ctagctctga gagaatccct aatcagaaca aagcactgtg cacttgaaat
      121 ggaattttcc tggggaagtg gccaggaatc ccagcgcttg cttctttctt ttctgcttct
      181 tgcaatctgg gaggcaggga acagccagat ccactactcc atccctgagg aggccaaaca
      241 cggcaccttc gtgggccgca tcgcgcagga cctggggctg gagctgacgg agctggtgcc
      301 ccgcctgttc agagtggcgt ccaaggaccg cggagacctt ctggaggtaa atctgcagaa
      361 tggcattttg tttgtgaatt ctcggatcga ccgggaggag ctgtgcgggc ggagcgcgga
      421 gtgcagcatc cacctggagg tgatcgtgga caggccgttg caggttttcc acgtggaggt
      481 ggaggtgagg gacattaacg acaaccctcc caggttccca acaacacaaa agaatctgtt
      541 cattgcagaa tcaaggccac ttgacacttg gtttccacta gagggcgctt cagacgcaga
      601 tatcggaatc aatgctgtac tgacttacag actgagtcca aatgattact tttctttgga
      661 aaaaccatcc aacgacgaac gggtaaaagg tcttggactt gtattacgga aatctttaga
      721 ccgggaggaa actccagaga taattttagt gcttactgtc acggacggag gaaagccaga
      781 gctgaccggc agtgttcagt tactcatcac tgtgctggat gccaatgata atgctccagt
      841 ttttgacaga tctctgtata ccgtgaaatt accagaaaac gttccaaatg ggacattggt
      901 agtcaaagtc aatgcctcag atttagacga aggggtaaat ggggatatta tgtactcatt
      961 ttctacagat atttcaccaa atgtgaaata caaattccac atagaccctg ttagcggaga
     1021 gattattgta aagggataca ttgattttga agaatgcaaa tcctatgaaa ttctcataga
     1081 gggaattgac aagggacaac ttccactctc tgggcactgt aaagtcattg tacaagttga
     1141 agacatcaac gataatgttc cagaattgga attcaaatct ctatcacttc caatacgaga
     1201 gaattctcca gtgggcactg tcatcgcact cattagtgtg tctgatcggg acacgggtgt
     1261 caacgggcag gtgacctgct ccctgacaag tcatgtcccc ttcaagttgg tgtccacatt
     1321 caagaattac tattcgctcg tgctggacag cgccctggac agagagacaa cagcggacta
     1381 taaggtggtg gtgacagcgc gggatggggg ctctccctcg ctgtgggcca cggctagcgt
     1441 gtctgttgag gttgctgacg tgaacgacaa tgcacctgtg ttcgcgcagc ccgaatacac
     1501 ggtgttcgtg aaggagaaca acccgcctgg tgcgcacatc ttcacggtgt cagcgatgga
     1561 tgcggacgca caggagaacg cgctggtgtc ctactcgctg gtggagcgga gggtgggcga
     1621 gcgcttgctg tcgagctatg tgtctgtgca cgcggagagc ggcaaggtgt tcgcgctgca
     1681 gcctctggac catgaggagc tggagctgct gcggttccag gtgagcgcgc gggatgctgg
     1741 tgtacctgcc ctgggcagca atgtgactct gcaggtgttt gtgctggacg agaatgacaa
     1801 cgcgcccaca ctgctggaac ctgaggcagg agtctctggt ggaatcgtga gccggttggt
     1861 gtccagatca gtgggtgcag gccatgtggt ggctaaggtg cgcgcggtgg atgcagactc
     1921 tggctataat gcatggctct cttatgagct gcaatcgtca gaaggcaatt cccgtagcct
     1981 tttccgcgta ggtttgtata cgggcgagat tagtactacg cgcatactgg atgaagcaga
     2041 ttcgccacgt cagcgccttc tggtgctggt gaaggaccat ggtgacccag caatgattgt
     2101 taccgccaca gtgttggtgt ctctggtaga gaatggcccg gtaccaaagg ctccatcgcg
     2161 agtatccacg agtgtcacac actctgaggc gtcactggtg gatgtcaacg tgtacctgat
     2221 cattgccatc tgtgcagtgt ccagcctgct agtgctcacg ctgctgctgt acacagcgct
     2281 gcgctgttcc actgtcccca gtgagagcgt gtgcgggcct ccaaaaccgg taatggtgtg
     2341 ctccagtgca gtggggagct ggtcatactc ccaacaaagg aggcaaaggg tgtgctctgg
     2401 ggagtaccca cctaagaccg acctcatggc cttcagcccc agtttatctg attcaaggga
     2461 cagagaggat caattgcagt ctgcagagga ttcctctgga aagcaagccc cgcccaacac
     2521 tgactggcgt ttctctcaag cccagagacc cggcacgagc ggatcccaaa atggtgatga
     2581 aactggcacc tggcccaaca accagtttga tacagagatg ctgcaagcca tgatcttggc
     2641 ctctgccagc gaagctgctg atgggagctc taccctggga gggggcgctg gcaccatggg
     2701 tctgagcgct cgatacggac cccagtttac cctgcagcac gtgcctgact accgccagaa
     2761 cgtgtacatc cctggcagca atgccacgct gaccaatgcc gctggcaaac gagatggcaa
     2821 ggctccagca ggtggtaatg gcaacaagaa gaaatcgggc aagaaagaga agaagtaata
     2881 tggaggccag gccttgaacc acaaggcagc ctccctcccc agccagtcca gctcgtcctt
     2941 acttgtaccc aggcctcaga atttcagggc tcaccccagg atactggtag gagccagggc
     3001 catgctcccc gttgggaaac agaaacacgt gcccaagcca acaccccctc tctataccct
     3061 agggagttga atatgcaaag agagttctgc tgggaccccc ctattcaatc agtgattgta
     3121 cccacatggg tagcagggtt tgtgtgtgtg gacatacaca cacacacaca cacacacaca
     3181 cacaaaccat gccacactcc cttagttaca gctgaactcc tccatcttcc aacccaggca
     3241 ggcttatcca tctcctgccg ccctctcccc accccaccca ctccttcagt ccctctcttt
     3301 gagcaaggta gctgggctgt tggggtgacc ggtgagctaa gccggctcct agttctgaac
     3361 ggtagggaga gtattacaat cttttggcct ctccttcagt tcagctttcc cccaaagcat
     3421 ggtttggtac cagtcttctc ttttccttcc agagcctgag accaatgctt aagttttggg
     3481 ggaacaggca ccctccctct ggtactgatg atgcttgctg gattttggga aggcattttg
     3541 ctactaagcc tcttttcaat gcctggggac aactagtctt ttgtttttca ttgtttgatg
     3601 ttcccactgc atgctgtgac ttccctacac ctcaaagaag agactccttt gcatgtctgg
     3661 agacagtagg gggtggtaaa ctaaagggaa gttgagagtg tatactgctg ggagtggggc
     3721 agtggacaaa acagcctgtt aatagggtct tgcaaggggc tctgtatgta cccaggggac
     3781 tggctcaatc ctcacattct agccatagac aaacaccagg ccagacccct ccattctggt
     3841 tcagcctggg cagcttgggc tgagccacca ggaccaatgg atttaagctg acatttcagt
     3901 ccaagacgac gacttctaag tgagtttaag accagagagg aaagaggggc ctctgtgggt
     3961 gctgggtact ccagaggtgc ccttggtggg aggaccagtg gtcttagcag gaaggggggc
     4021 ccagcaaggt cattcttgga ccctgggtct agtccagtag ctagaaaaag ggaccaagtg
     4081 gccataaagt cccagccaat gatggggctt ttccagtggg cccctgtaga cctcaagccc
     4141 ctggcctcca ccttaccagg tgccatttct tctcagaagg ccactgccca ggcccccagg
     4201 ccgccccctt gtggccagag aacggttaaa gccccccagt gcctccttgt gcatagaact
     4261 tcctctgccc tagcccttac agtagtgtag aagatccccc tcccccgctg gtgtagaata
     4321 gccaatagta tagtgtggtg tgcttttacg tgatggcgag tgggcagcgg gcggtgggct
     4381 gtacacagcc gtctgtcctt tgaatctcaa tctgcctgcg cggcccgtgc tgtgttttgt
     4441 gctgtgtcca cacgctgcgg cgacccctcc ctgtactgac ttctctataa aaagcttctc
     4501 ttcgcatagt cacgtagctc ctgcccatcc cccttccgat atctctcgca agttttatac
     4561 tctaatattt atatggcttt tttcttcgaa aattaaaaat aaaaaaatgg tttcttctga
     4621 aa
//
