LOCUS       NM_001142742            6303 bp    mRNA    linear   ROD 10-DEC-2024
DEFINITION  Mus musculus protocadherin 15 (Pcdh15), transcript variant I, mRNA.
ACCESSION   NM_001142742
VERSION     NM_001142742.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6303)
  AUTHORS   Shigesawa,I., Nakamura,A., Yamauchi,Y., Kawata,S., Miyazaki,A.,
            Nomoto,H., Kameda,H., Terauchi,Y. and Atsumi,T.
  TITLE     Effects of glucokinase haploinsufficiency on the pancreatic
            beta-cell mass and function of long-term high-fat, high-sucrose
            diet-fed mice
  JOURNAL   J Diabetes Investig 15 (12), 1732-1742 (2024)
   PUBMED   39305123
REFERENCE   2  (bases 1 to 6303)
  AUTHORS   Mori,D., Inami,C., Ikeda,R., Sawahata,M., Urata,S., Yamaguchi,S.T.,
            Kobayashi,Y., Fujita,K., Arioka,Y., Okumura,H., Kushima,I.,
            Kodama,A., Suzuki,T., Hirao,T., Yoshimi,A., Sobue,A., Ito,T.,
            Noda,Y., Mizoguchi,H., Nagai,T., Kaibuchi,K., Okabe,S.,
            Nishiguchi,K., Kume,K., Yamada,K. and Ozaki,N.
  TITLE     Mice with deficiency in Pcdh15, a gene associated with bipolar
            disorders, exhibit significantly elevated diurnal amplitudes of
            locomotion and body temperature
  JOURNAL   Transl Psychiatry 14 (1), 216 (2024)
   PUBMED   38806495
  REMARK    GeneRIF: Mice with deficiency in Pcdh15, a gene associated with
            bipolar disorders, exhibit significantly elevated diurnal
            amplitudes of locomotion and body temperature.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6303)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 6303)
  AUTHORS   Lee,J.H., Perez-Flores,M.C., Park,S., Kim,H.J., Chen,Y., Kang,M.,
            Kersigo,J., Choi,J., Thai,P.N., Woltz,R.L., Perez-Flores,D.C.,
            Perkins,G., Sihn,C.R., Trinh,P., Zhang,X.D., Sirish,P., Dong,Y.,
            Feng,W.W., Pessah,I.N., Dixon,R.E., Sokolowski,B., Fritzsch,B.,
            Chiamvimonvat,N. and Yamoah,E.N.
  TITLE     The Piezo channel is a mechano-sensitive complex component in the
            mammalian inner ear hair cell
  JOURNAL   Nat Commun 15 (1), 526 (2024)
   PUBMED   38228630
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6303)
  AUTHORS   Krey,J.F., Chatterjee,P., Halford,J., Cunningham,C.L., Perrin,B.J.
            and Barr-Gillespie,P.G.
  TITLE     Control of stereocilia length during development of hair bundles
  JOURNAL   PLoS Biol 21 (4), e3001964 (2023)
   PUBMED   37011103
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6303)
  AUTHORS   Raphael,Y., Kobayashi,K.N., Dootz,G.A., Beyer,L.A., Dolan,D.F. and
            Burmeister,M.
  TITLE     Severe vestibular and auditory impairment in three alleles of Ames
            waltzer (av) mice
  JOURNAL   Hear Res 151 (1-2), 237-249 (2001)
   PUBMED   11124469
REFERENCE   7  (bases 1 to 6303)
  AUTHORS   Alagramam,K.N., Zahorsky-Reeves,J., Wright,C.G., Pawlowski,K.S.,
            Erway,L.C., Stubbs,L. and Woychik,R.P.
  TITLE     Neuroepithelial defects of the inner ear in a new allele of the
            mouse mutation Ames waltzer
  JOURNAL   Hear Res 148 (1-2), 181-191 (2000)
   PUBMED   10978835
REFERENCE   8  (bases 1 to 6303)
  AUTHORS   Alagramam,K.N., Kwon,H.Y., Cacheiro,N.L., Stubbs,L., Wright,C.G.,
            Erway,L.C. and Woychik,R.P.
  TITLE     A new mouse insertional mutation that causes sensorineural deafness
            and vestibular defects
  JOURNAL   Genetics 152 (4), 1691-1699 (1999)
   PUBMED   10430593
REFERENCE   9  (bases 1 to 6303)
  AUTHORS   Zobeley,E., Sufalko,D.K., Adkins,S. and Burmeister,M.
  TITLE     Fine genetic and comparative mapping of the deafness mutation Ames
            waltzer on mouse chromosome 10
  JOURNAL   Genomics 50 (2), 260-266 (1998)
   PUBMED   9653653
REFERENCE   10 (bases 1 to 6303)
  AUTHORS   Osako,S. and Hilding,D.A.
  TITLE     Electron microscopic studies of capillary permeability in normal
            and ames waltzer deaf mice
  JOURNAL   Acta Otolaryngol 71 (5), 365-376 (1971)
   PUBMED   5093631
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ166718.1, DQ354405.1 and AK139154.1.
            
            Transcript Variant: This variant (I) includes an alternate in-frame
            exon in the central coding region and has a distinct 3' splice
            pattern, compared to variant A. The resulting isoform (CD2-1), also
            known as protocadherin-15-CD2 isoform 1, includes an alternate 7-aa
            segment in the central coding region and has a distinct and longer
            C-terminus, compared to isoform CD1-1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ354405.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN01164131,
                                           SAMN01164132 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-16                CJ166718.1         1-16
            17-2264             DQ354405.1         1-2248
            2265-2265           AK139154.1         2169-2169
            2266-3143           DQ354405.1         2250-3127
            3144-3144           AK139154.1         3048-3048
            3145-6303           DQ354405.1         3129-6287
FEATURES             Location/Qualifiers
     source          1..6303
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 37.43 cM"
     gene            1..6303
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /note="protocadherin 15"
                     /db_xref="GeneID:11994"
                     /db_xref="MGI:MGI:1891428"
     exon            1..393
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            394..512
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            513..527
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            528..593
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            594..754
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            755..910
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1030
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1141
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            1142..1312
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1421
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1534
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            1535..1741
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            1742..1762
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1897
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            1898..2047
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            2048..2241
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            2242..2374
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            2375..2454
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            2455..2548
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            2549..2677
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            2678..2983
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            2984..3208
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            3209..3325
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            3326..3466
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            3467..3579
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            3580..3689
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            3690..3830
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            3831..3958
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            3959..4174
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            4175..4263
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            4264..4440
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            4441..4659
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            4660..4668
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            4669..4824
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            4825..4830
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            4831..4939
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
     exon            4940..6303
                     /gene="Pcdh15"
                     /gene_synonym="av; Gm9815; nmf19; roda; Ush1f"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttttcagcca gctgatcaac gtgctgcgct aatagccaca gatagagggc ctgcggatgc
       61 ctgctagcag cttggggtta gtttctcctg gtacctgagg cagttggcaa gcacctccga
      121 acacggaggg ggcagatagg atgcctcctc ggttagtacg ttaagggatt ctgtttatgc
      181 atctccagta atttttattt ttttaatgtg tgtggtgaaa cgaaagtgga taataatgct
      241 tcatcagaaa caagagcata atttgtgaat gaatcagtca tcttcagact taagagagcg
      301 agcgctggtg gtttgtaaag agatgtgcag aagcgatctt ggcacaggga cctactgcct
      361 ggactcgtgt cgactaaaga tgaaacttta aagatcagcc tcaagtgaaa tttgacagaa
      421 gatgttccta cagtttgctg tctggaagtg tttaccccat gggatcctca ttgcctctct
      481 cttggtagtc agctggggcc agtatgacga tgactggcaa tacgaggatt gcaaactagc
      541 taggggagga ccaccagcta ctatcgtggc cattgatgaa gagagtcgaa acggtacaat
      601 tctggtggat aacatgttga ttaaggggac tgccggagga ccagacccca ccatagagct
      661 ctctttaaag gacaacgtgg actactgggt gttgctggac cccgttaaac agatgctttt
      721 cctgaacagt accggaagag ttctggatag agacccacca atgaacatac actccattgt
      781 ggtgcaagtc cagtgtgtca acaagaaggt tggcacagtt atctatcatg aagtacgcat
      841 cgtggtgcga gatcggaatg acaactcccc cacattcaag catgaaagct actatgccac
      901 cgtgaatgag ctcactccag ttggcaccac gatattcacg gggttctcgg gagacaatgg
      961 agctacagac atagacgatg gccctaatgg acagatagaa tacgtgattc agtacaaccc
     1021 agaagatccg acatccaacg acacctttga aattccactc atgctgactg gcaacgtggt
     1081 actgaggaaa agactcaact atgaggataa gactcgctac tatgtcatca tccaagcaaa
     1141 tgaccgtgca caaaatctga atgagaggcg aacaaccacc accaccctca cagtagatgt
     1201 tctagatgga gatgacctgg gacctatgtt tctgccttgt gttcttgtgc caaacacacg
     1261 tgactgtcgt ccactcacct accaagctgc cattcctgaa ctgaggactc cggaagaact
     1321 gaaccctatt ttggtgacac cacctatcca agccattgat caggaccgaa acatccaacc
     1381 accatctgat cgacctggca tcctctactc catccttgtc ggcacccctg aggattaccc
     1441 ccgcttcttc catatgcatc ccaggactgc agaactcact ctcctggagc cagtaaacag
     1501 agacttccat caaaaatttg atttggttat taaggctgag caggacaatg gccacccact
     1561 tcctgccttt gctagtctgc acatcgaaat actagacgaa aacaatcaga gtccatactt
     1621 cacaatgccc agctatcaag gatacatcct ggaatccgcc ccagtgggag ccaccatttc
     1681 tgagagccta aacttaacca ctcctctgag aattgtagct ctggacaaag acatagaaga
     1741 cgtgccacct ggtggagttc ctacaaaaga tccagagctc cacctcttcc tgaatgacta
     1801 cacctcggtc ttcactgtga cacccactgg tatcacccgc tacctcaccc tgcttcaacc
     1861 tgtggacagg gaggaacagc aaacctacac ctttctgata acagcgtttg atggcgtgca
     1921 agaaagtgag ccagtcgtgg tcaatatccg agtgatggat gcaaatgata acacgcccac
     1981 cttccctgaa atctcctatg atgtctatgt ttacacagac atgagtcctg gggacagcgt
     2041 cattcagctg acagcggtag atgctgatga aggctctaat ggggagatct cctatgaaat
     2101 actggtgggg ggcaagggag acttcgtgat caacaagacc acagggctgg tgagcattgc
     2161 accaggcgtg gagctgatcg tgggacagac gtatgcgctc acagtgcagg cttcggacaa
     2221 cgccccgcct gcagaaagaa ggcactccat ctgcacagtg tacatcgagg tgcttcctcc
     2281 taacaaccag agccctcccc gcttcccgca gctgatgtac agtctggaag tcagcgaggc
     2341 catgaggatc ggtgctattt tattaaatct acaggcaact gatcgagagg gagatccaat
     2401 cacatatgcc atcgagaatg gagaccctca gagagttttt aatctttcag aaaccacagg
     2461 gattctcagc ctagggaagg ctctagaccg cgagagcaca gaccgctaca tcctcatcgt
     2521 cacagcctca gatggcagac cggatggaac ctcaactgcc actgtgaaca tagtggtgac
     2581 ggacgtcaat gacaacgctc ccgtgttcga tccctatctg cccaggaacc tctctgtggt
     2641 ggaggaagaa gccaatgcct ttgtgggtca agtccgggca acagacccag atgctgggat
     2701 aaacggccaa gttcactaca gcctggggaa cttcaacaac ctcttccgca tcacatccaa
     2761 cgggagcatt tacacagccg tgaagctgaa cagggaagcc agggaccact atgaactggt
     2821 tgtcgtggca acagatggag cagtccaccc tcgacattca actctgacac tgtacatcaa
     2881 ggtgttggac attgatgata acagtcctgt ttttaccaat tcaacgtaca cagttgtcgt
     2941 tgaagagaat ctgccagccg ggacctcctt tcttcaaata gaggccaagg atgttgacct
     3001 tggagccaat gtgtcatatc ggatcagaag cccagaagtg aaacaccttt ttgcactgca
     3061 tccattcact ggagaattgt ctcttctgag gagtttggat tatgaggcct ttccggacca
     3121 ggaggcaagc atcacattct tggtggaggc ctttgacatt tatgggacta tgccacctgg
     3181 tatagcaaca gtcacggtaa ttgtgaagga catgaatgac taccctccag tgtttagcaa
     3241 acgcatctac aaggggatgg tggctccaga tgcagtcaag gggacaccaa tcaccaccgt
     3301 ttatgctgaa gatgcggacc cacctgggat gcctgcaagt agggtgaggt atcgagtgga
     3361 cgacgtgcag tttccatacc cagccagtat ttttgatgta gaggaagatt ctggaagagt
     3421 agtaacccgc gtcaatctta atgaagagcc tactacgatt ttcaagctgg tggttgtggc
     3481 ttttgatgac ggcgaacctg tgatgtccag cagtgccacg gtgagaattc ttgtcttaca
     3541 tcctggagag atcccacgct tcacccaaga ggaatacaga cctcctcctg taagtgagct
     3601 tgcggccaga gggactgtag ttggtgtcat ttctgctgct gccattaatc agagcatcgt
     3661 gtactccatt gtggcaggaa atgaggaaga caagtttgga atcaacaatg tcactggggt
     3721 catctatgtg aattcaccat tggattacga gacaaggacc agctatgtgc tccgggtaca
     3781 agcagattct ctggaagtgg tccttgccaa tctccgagtc ccttcaaaaa gcaatacagc
     3841 taaggtgtac attgagattc aggatgaaaa cgatcacccc ccagtgttcc agaagaaatt
     3901 ctacattgga ggtgtgtctg aagacgcaag gatgttcgca tctgtgctca gagtgaaggc
     3961 caccgacagg gacacgggta attacagtgc catggcctac cggctcatca taccgccgat
     4021 taaagagggc aaagaggggt ttgtggtgga aacatacaca ggtctcatca agacagccat
     4081 gctcttccac aatatgagaa gatcctactt caagtttcaa gtgattgcaa ctgacgacta
     4141 cgggaagggg ttgagcggga aagcagacgt actggtctcc gtggtcaatc aactggatat
     4201 gcaggtcatt gtctccaatg tgccccctac actagtggaa aagaagatag aagaccttac
     4261 agagattttg gatcgctacg ttcaggagca aattcctggt gccaaggttg tggtggagtc
     4321 cataggtgcc cgtcgccatg gagacgccta ctccctagaa gactatagca agtgcgacct
     4381 gactgtctat gccatcgacc cgcagaccaa cagagccatc gacagaaatg agctttttaa
     4441 gttcctggac ggcaaactgc tcgatatcaa taaagacttc cagccgtatt acggggaagg
     4501 agggcgcatt ctggagattc ggacacctga ggcagtgacg agcatcaaga agcgaggaga
     4561 aagcttgggg tacacagaag gggccttgct ggccttggcc ttcatcatca tcctctgttg
     4621 catcccagcc atcttggtcg tcttagtaag ctaccgacag tttaaagtac gccaggctga
     4681 gtgcacgaag accgcaagaa ttcagtctgc tatgcctgca gccaagcctg cagctcctgt
     4741 accagctgcg cctgcgccgc ccccgccccc gccaccacca ccaccaggag cacatctcta
     4801 tgaagaactg ggagagagcg caatgcataa gtatgagatg ccccagtatg gaagtcgccg
     4861 tcgactgctg ccacctgctg gacaggagga atacggcgaa gtcattggtg aagctgaaga
     4921 ggaatatgaa gaagaagagg tagagccaga gaaagttaaa aaacccaaag ttgaaattag
     4981 agagcctagt gaggaggagg tggtagtcac cgttgagaag ccaccagcgg ctgagcccac
     5041 atacccaacg tggaagagag ccaggatatt cccgatgatt tttaagaaag tcagaggtct
     5101 cgctgagaaa agaggcattg accttgaggg cgaggagtgg aggaggcgcc ttgatgaaga
     5161 agacaaagac tatcttcaac tgactctaga ccaggaggaa gctaccgaaa gcaccgtgga
     5221 gtcagaggag gagtccagcg actacacaga atacacagaa acggagtccg agttcagcga
     5281 gtccgagaca actgaagaat cagagtcgga gaccccatct gaggaagcgg aggagagctc
     5341 taccccggag tcagaggagt ctgagtccac tgagtcagag ggagagaaag caagaaaaaa
     5401 catcgtgcta gctagaagaa ggcctgtggt cgaggaaatc caggaggtga aaggtaagag
     5461 agaggagccc ccggtggaag aggaagaaga gcccccacta gaggaggaag aacgggcaga
     5521 ggaaggagaa gaaagcgaag cagctcccat ggatgagtcc acagacctgg aggctcagga
     5581 tgtcccagag gagggcagtg cagaatcagt ctccatggag aggggcgtgg aaagtgagga
     5641 gtcagagtca gaactgagca gcagcagcag taccagtgag agtctctccg gaggcccctg
     5701 gggctttcag gtgccagaat atgacagaag gaaggatgaa gagcccaaga aatctccagg
     5761 cgcaaactcc gaaggttaca acacagccct ttagaagaga gttcacagta ggtgggggtt
     5821 tgcagtgaca tgtgctcctg tgtgcggtgc cttctgtgtg gtctctgaaa cggctcctga
     5881 cagggtgggg acttagcatg atttgtctct ctgactcatg gttagaagta agataagaaa
     5941 atgatcacct atgctaccta cgtagacgtg cttgctgaga tatggtagat caaacctgtc
     6001 taactctctc ttctactagc aaacagggaa acatcaatac tgactataaa gtggcattat
     6061 cagtgacact tgtctatagc aatggaacat acacacatat gtgataaata gtctttgcag
     6121 agtagatact aacaaacaga aacaaataat gtgagtaact gtttctgatt atttctgctc
     6181 cctgagaagg tgaccagtca aagataccct gtatcaactc ccaccttcaa attctaggag
     6241 ttaaatgaaa ccgtatcttg aaagttaaaa ccctttaggt tgtgtttaaa atctaacagt
     6301 cac
//
