LOCUS       NM_001403635            9002 bp    mRNA    linear   ROD 26-NOV-2024
DEFINITION  Mus musculus protocadherin 11 X-linked (Pcdh11x), transcript
            variant 6, mRNA.
ACCESSION   NM_001403635
VERSION     NM_001403635.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9002)
  AUTHORS   Lo Giudice,Q., Wagener,R.J., Abe,P., Frangeul,L. and Jabaudon,D.
  TITLE     Developmental emergence of first- and higher-order thalamic neuron
            molecular identities
  JOURNAL   Development 151 (18) (2024)
   PUBMED   39348458
REFERENCE   2  (bases 1 to 9002)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 9002)
  AUTHORS   Markenscoff-Papadimitriou,E., Binyameen,F., Whalen,S., Price,J.,
            Lim,K., Ypsilanti,A.R., Catta-Preta,R., Pai,E.L., Mu,X., Xu,D.,
            Pollard,K.S., Nord,A.S., State,M.W. and Rubenstein,J.L.
  TITLE     Autism risk gene POGZ promotes chromatin accessibility and
            expression of clustered synaptic genes
  JOURNAL   Cell Rep 37 (10), 110089 (2021)
   PUBMED   34879283
REFERENCE   4  (bases 1 to 9002)
  AUTHORS   Bibollet-Bahena,O., Okafuji,T., Hokamp,K., Tear,G. and
            Mitchell,K.J.
  TITLE     A dual-strategy expression screen for candidate connectivity labels
            in the developing thalamus
  JOURNAL   PLoS One 12 (5), e0177977 (2017)
   PUBMED   28558017
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 9002)
  AUTHORS   Hertel,N., Redies,C. and Medina,L.
  TITLE     Cadherin expression delineates the divisions of the postnatal and
            adult mouse amygdala
  JOURNAL   J Comp Neurol 520 (17), 3982-4012 (2012)
   PUBMED   22592879
REFERENCE   6  (bases 1 to 9002)
  AUTHORS   Hertel,N. and Redies,C.
  TITLE     Absence of layer-specific cadherin expression profiles in the
            neocortex of the reeler mutant mouse
  JOURNAL   Cereb Cortex 21 (5), 1105-1117 (2011)
   PUBMED   20847152
REFERENCE   7  (bases 1 to 9002)
  AUTHORS   Kim,S.Y., Yasuda,S., Tanaka,H., Yamagata,K. and Kim,H.
  TITLE     Non-clustered protocadherin
  JOURNAL   Cell Adh Migr 5 (2), 97-105 (2011)
   PUBMED   21173574
  REMARK    Review article
REFERENCE   8  (bases 1 to 9002)
  AUTHORS   Krishna-K,K., Hertel,N. and Redies,C.
  TITLE     Cadherin expression in the somatosensory cortex: evidence for a
            combinatorial molecular code at the single-cell level
  JOURNAL   Neuroscience 175, 37-48 (2011)
   PUBMED   21129452
REFERENCE   9  (bases 1 to 9002)
  AUTHORS   Vanhalst,K., Kools,P., Staes,K., van Roy,F. and Redies,C.
  TITLE     delta-Protocadherins: a gene family expressed differentially in the
            mouse brain
  JOURNAL   Cell Mol Life Sci 62 (11), 1247-1259 (2005)
   PUBMED   15905963
REFERENCE   10 (bases 1 to 9002)
  AUTHORS   Blanco-Arias,P., Sargent,C.A. and Affara,N.A.
  TITLE     A comparative analysis of the pig, mouse, and human PCDHX genes
  JOURNAL   Mamm Genome 15 (4), 296-306 (2004)
   PUBMED   15112107
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX005163.13, BX005446.8,
            AC115298.6, AC117258.2, BX255884.7 and BX005240.7.
            
            Summary: This gene encodes a member of the protocadherin family,
            and cadherin superfamily, of transmembrane proteins containing
            cadherin domains. The encoded protein may mediate cell-cell
            adhesion in neuronal tissues in the presence of calcium.
            Alternatively spliced transcript variants have been observed for
            this gene. [provided by RefSeq, Nov 2012].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR9219382.116767.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMN01164131, SAMN01164136 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-325               BX005163.13        143581-143905
            326-663             BX005163.13        144249-144586
            664-1247            BX005446.8         31435-32018
            1248-3743           BX005446.8         66051-68546
            3744-3824           AC115298.6         80491-80571         c
            3825-3854           AC115298.6         37652-37681         c
            3855-4053           AC117258.2         83407-83605         c
            4054-4077           BX255884.7         3035-3058
            4078-9002           BX005240.7         81657-86581
FEATURES             Location/Qualifiers
     source          1..9002
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 49.58 cM"
     gene            1..9002
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /note="protocadherin 11 X-linked"
                     /db_xref="GeneID:245578"
                     /db_xref="MGI:MGI:2442849"
     exon            1..325
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /inference="alignment:Splign:2.1.0"
     exon            326..663
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /inference="alignment:Splign:2.1.0"
     exon            664..1247
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /inference="alignment:Splign:2.1.0"
     CDS             708..4724
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /note="isoform c precursor is encoded by transcript
                     variant 6; protocadherin X-linked 11"
                     /codon_start=1
                     /product="protocadherin-11 X-linked isoform c precursor"
                     /protein_id="NP_001390564.1"
                     /db_xref="GeneID:245578"
                     /db_xref="MGI:MGI:2442849"
                     /translation="MDLLSGTYIFAVLLACVVFQSGAQEKNYTVREEMPENVLIGDLL
                     KDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVL
                     DARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSL
                     PAAIDPDIGINGVQNYQLIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMK
                     VKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDA
                     DIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGS
                     TPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEH
                     NGRVTCFTDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSS
                     MLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFD
                     APPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDN
                     SPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAVTLSILDVNDQFTIDPQSGV
                     IRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSNYSF
                     EWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCM
                     VSDLGLHRVIVKANDLGQPDSLFNVVNVNFFINESVPNATLIYELVRRSIDAPANQNT
                     ETTSASSPTTDYVKIMVAIVAGTITVVLVIFITAVVRCRQPPHLKASQKNKQNSEWVT
                     PNPENRQMIMMKKKKKKKKKHPPKNLLLNFVTIEEAKPDDGENERNSVTLDLPIELEE
                     QTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNT
                     FVGCDSISKCSSSSSDPYSVSECSYPVTTFKAPVSVHIRPTMKEVVRSHTPMKEATTV
                     EIWTHPHPQRRSDGKKAGKSQRRVTFHLPEGSQESISDGGLGDHDAGSLPSTSHALPL
                     GYPQEEYFDHAAPNNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDTCTQECLI
                     LGHSDSCWMPATLTNPSPSQIKTSAICHSPPRPRLSVRRYSPPVTQTVTICHSPPVTQ
                     AIALCHSPPPVQVTVPRHSPPPAQASAVSYSPTLVQAVVIHHSPPLPQAATHHRTQAQ
                     PPMGLQQGWVQGAGADGLYPIDQGVQGSTRAQFYTMAERFHPDDDSIKVIPLTTFTSG
                     QQARSSRGDSPIIEEHPL"
     exon            1248..3743
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /inference="alignment:Splign:2.1.0"
     exon            3744..3824
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /inference="alignment:Splign:2.1.0"
     exon            3825..3854
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /inference="alignment:Splign:2.1.0"
     exon            3855..4053
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /inference="alignment:Splign:2.1.0"
     exon            4054..4077
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /inference="alignment:Splign:2.1.0"
     exon            4078..9002
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8980..8985
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /note="hexamer: AATAAA"
     polyA_site      9002
                     /gene="Pcdh11x"
                     /gene_synonym="Pcdh11; PCDHX; PCDHX11"
                     /note="major polyA site"
ORIGIN      
        1 gcagtcgacg aactgtcagg gcgggagtag ctgtgagcca gagcagccag cagcggcccg
       61 cgcagcaaag cggaaagcta ggctaccaga gtgcaaggag tctcagtggc agaagctact
      121 caggcgacac aggcagccca gctagcccgg gccgcccgac cagcctcaca aacagcctcc
      181 aagacaaaca gctgctctgc ggactgcgag ctgtggcggt agatcccgct acagcaatcg
      241 cagtctctgt ggagcgggcg gaagcctttt tttctccttt ttcgttcccc tcttcatact
      301 actcaaagag gagtctaaac agtagcttca gcgaagctga atgaaactct gatctgggaa
      361 agtgcgggga tgcagagttg acgccccaga ccattagggg agacacctgg agcaagtcca
      421 gctgaggggc agtgtgcctc agcagtgaat ccgcggtgga ccctggaagc tggcccagct
      481 gcgctcctct ctggggtctc cgatttgagt ccaggtttga tagcgcaacc cggttgggga
      541 gcgacccttg ccgcagggct tcggaaaact gtgcgcacag cagggcgccc agcgtctact
      601 ggattggtcc tcctggtatg atcccatttc ttcctgccct gggacctagt ggatgtagag
      661 atgtatatcg tgggctgaca aacagtacct ttggtattga gactggtatg gacttgttgt
      721 ccgggacgta tatatttgcg gtcctgttag catgcgtcgt gtttcagtct ggcgcccagg
      781 agaagaatta tacagtccga gaagaaatgc cagaaaacgt cctgataggc gacttgttga
      841 aagacctcaa cttgtcgctt attcccgaca agtccttaac cactcctatg cagttcaaat
      901 tagtttacaa aaccggggat gtaccattga ttcgcattga agagggtact ggagagatct
      961 tcactactgg tgcacgcatt gatcgtgaga aattatgtgc tggaatcgtg ttggatgccc
     1021 gttgctttta cgaagtggag gttgctgttt tgccggatga aatatttcga ttggttaaga
     1081 tacgctttct gattgaagac ataaatgata atgcaccgtt attcccaaca actgtcatca
     1141 acatatcaat tccggagaac tcggctataa actctcgata ttctcttcca gcagccattg
     1201 atcctgacat tggaataaat ggagtccaaa attaccaact aattaagagt caaaatattt
     1261 tcggacttga tgtcattgaa acaccagaag gagacaagat gccccaactg attgttcaaa
     1321 aggagttaga tagagaagag aaggatacct atgtgatgaa agtaaaagtt gaagatggtg
     1381 gctttcctca aagatccagt acagctattt tgcaagtaag tgttgctgat acaaacgaca
     1441 atcacccaat cttcatagaa aaggaaattg aagtcagtat accagaaaat gctcctatag
     1501 gttcttcagt gacacagctc catgccacag atgcagatat aggtgagaat gccagaattc
     1561 acttttattt cagcaaccta gtctccaaca tcgctaagag actgtttcat ctaaacacca
     1621 ctactggact tatcactgtc aaagaaccac tggataggga agaatcacca agtcacaagt
     1681 tattggtttt ggcaactgat ggtggatcaa caccagcaag agcaacggtg ctggtaaatg
     1741 tcacagatat caatgataat gtcccatcaa ttgacataag atacattgtc aatccaacca
     1801 atggcactgt gcttctttca gagaatgctc cacttaacac taaaattgct ctcataactg
     1861 tgatggataa ggattctgaa cataatggta gggtgacatg cttcacagat catgaagttc
     1921 ctttcagatt gcgaccagta ttcagtaatc agtttctctt ggagactgct gcatttcttg
     1981 actttgagtc cacaagagaa tatgccataa aattactagc cgctgatgct ggcaaacctc
     2041 ctttgaatca gtcatccatg ctcctgatca aagtaaaaga tgaaaatgac aatgctccag
     2101 ttttcaccca gtctttcata agcctttctg ttcctgagaa taactctcct ggtgcacagt
     2161 tgacaaaaat cagtgcaaca gatgcagaca gtggacagaa tgctgaaata agctacatgc
     2221 taggttttga tgcaccacct gaattcaatc tggatcaacg tactggcatc ctgactgcag
     2281 tgaagaaact agatagggaa aaacaggaaa agtattactt tacagttttg gcacaggaca
     2341 atggaattcc acccttaatg tccaatgcca ctgtatttgt gactgttctt gaccagaatg
     2401 ataatagccc aattttcact cataatgaat ataacttcta tgttcctgaa agccttccaa
     2461 aacatggcac agtagggcta ataactgtga ctgatcctga ttacggagag aattctgcag
     2521 ttaccctctc catcttagat gtgaatgatc aattcactat tgatccacag tctggtgtca
     2581 tcaggccaaa tatttcattt gacagagaaa gacaagaatc ctatactttc tatgtaaaag
     2641 ctgaggatgg tggtagggta tcacgttctt caactgctag agtaaccata aatgtggttg
     2701 atgtcaatga taacaaacca atttttattg accctccttc caattactcc tttgaatggg
     2761 ttctaccatc cacaaaccct ggcacagttg tcttcaaggt tgttgcaatt gacgatgata
     2821 ttggcatgaa tgcagaggtt ctttacagca ttgttggagg aaatacaaaa ggactgttta
     2881 tgattgaaca aacatcaggt aacatcacat tgaaggagaa gtgcatggtt tcagatcttg
     2941 gtttacaccg agtcatagtc aaagctaatg atttaggaca acctgattct ctcttcaatg
     3001 ttgtaaatgt caatttcttt ataaatgagt ccgtgcccaa tgccacactg atttatgaac
     3061 tggtgcgcag aagcattgat gcacctgcca atcaaaatac tgaaacaacc agtgcatcct
     3121 caccaaccac tgactatgtc aagatcatgg ttgccattgt ggctggcacc ataactgttg
     3181 tcctagttat tttcatcact gctgtagtaa gatgccgcca accaccacat cttaaggctt
     3241 ctcagaaaaa caaacagaat tctgagtggg ttactccaaa cccagaaaac aggcagatga
     3301 ttatgatgaa gaagaagaag aaaaagaaga agaagcatcc ccccaagaac ttgctgctta
     3361 attttgtcac tattgaagaa gcaaagccag atgacggtga aaatgagaga aacagtgtca
     3421 cactagatct tccaattgag ctggaagagc aaaccatggg caaatacaac tggggcacta
     3481 cacctactac tttcaaacct gatagccctg atttggctcg acactacaaa tcggcctctc
     3541 ctcagcctgc attccagatc cagcctgaaa cgcccctgaa ctcaaagcac cacatcattc
     3601 aggaactgcc tcttgataat accttcgttg gctgtgattc catctccaag tgctcctcca
     3661 gcagttctga tccctacagt gtttctgagt gtagctatcc agtgacaact ttcaaggccc
     3721 ctgtgtctgt gcatatcaga ccgacaatga aggaggtggt aagatctcac acacccatga
     3781 aagaggcaac cactgtggaa atctggactc atccacatcc acagcggcga tctgatggga
     3841 aaaaagcagg aaagtcccag agacgtgtca catttcacct accagaaggc tctcaggaaa
     3901 gcatcagtga tggtggattg ggagaccacg atgcaggcag ccttcccagt acatcccatg
     3961 cactgcctct tggctatcct caggaagagt attttgatca tgctgcacca aacaaccgca
     4021 ctgaagggga tggcaactct gatcctgaat ctactttcat tcctggacta aagaaagctg
     4081 cagaaataac agtgcagcca actgtggaag aagcctctga tacctgtact caagaatgcc
     4141 tcatcttggg acactctgac tcctgctgga tgccagctac tttgaccaat cctagccctt
     4201 cacagataaa gacctctgct atctgccaca gcccacccag gccccgcttg tcagttcgtc
     4261 gctacagccc tccagtgaca cagacggtca ctatttgcca cagcccccct gtgacccaag
     4321 ctattgcact gtgtcacagc cctccaccag tacaggttac tgtaccccgc catagtccac
     4381 caccagcaca ggcctctgca gtcagctaca gcccaactct agtacaggct gtggtaattc
     4441 accacagtcc tcctctgcca caggctgcca cacaccatcg cactcaggca caaccaccaa
     4501 tgggtttgca gcagggatgg gtgcagggtg ctggagcaga tggactgtat cctattgatc
     4561 agggagtaca gggcagtaca agagctcagt tttacaccat ggctgaaaga tttcatcccg
     4621 atgatgactc aattaaagtc attcccttga ccacctttac ttcaggtcaa caggccagat
     4681 cctcaagagg tgattctcca atcatagagg aacacccctt gtaaagccta tatggatact
     4741 tcacatttta aaaaagatgt atataaacat actcaaagat taacattcaa ttttaatgaa
     4801 tattccaaat tggcagattt gtaaatagct gtgtaaatag aaacagatac cagaataaga
     4861 ctagagctag acccttagtc acaagataat aaaataaatt taaaatttaa tttggtttgt
     4921 gaattttcaa aagaagtaaa tactttatat tcctttgtac agaaaggctt atcatgacag
     4981 aaattaatat gtagtatata atatttctga tgtactctga tgaattttta tttttttcca
     5041 ccatgtgcaa tattactgat ttcttctttt ctgatttttg tggattcagt aagtagttat
     5101 tgggaaattg gccaagatct gattttccaa gtttagcttt agtttgtctg actttccaag
     5161 tttaccttta gtttttgtaa atattgtttc agataaaatt agatggcaca attctatagt
     5221 atttttgttc atcttttgtt ttgtttatcc tagttgcctt tagtttcttt tttattgtct
     5281 gtatttctaa cttcaaaaat gtacagtagg gggtgtaaat aaaatctttt ccagtttttg
     5341 tctctatccc tattttttat tttttctacc tttatttcaa gtatatattg atataatttg
     5401 tatatacatg ttttcacaaa gaacatatat aaactgtaca gaactaggtt tcaacctatt
     5461 tctctactct ttagtagagt tcgagacact gaagtgcaat agctaagccc aaattaggca
     5521 actattagcc agaatgggcc tgtgcttttt tttatattta tatatttttg tagtgtagtg
     5581 tagtgtaaag tacatcagaa atactattgt atatgccatg ataagcctat ataccaataa
     5641 aaattgggta tgtatcttct ggaacttgta tataaaagtc acaaagaagg tgggtatgtt
     5701 caatgaatta ttagtacaca actattactg caaagcatta tttctaaaga taattgagat
     5761 gatttaaata tcgatttgat agctcaattg atgttattga aaatgctcag taaaaagaac
     5821 aaacaaataa aattgtacat aaaaccccat actaaggata taaggctaag ggaatatttt
     5881 tatcaatcta gctcaattta ctgaagaaaa ctactgaaaa caaggtgaaa gtcaggaaag
     5941 aacttttcaa gagacttaat tctaaatcta ccaagtgtat tacagcactg aatttcaagg
     6001 agatgtgcag agggagaatt gaggttcatg actgcatctt ggggtggata agaaataccc
     6061 cagtaacaca ctgaatgaca aaatctcaca tatgacacaa atacattata agcaaagaat
     6121 acagtagtat ccatagtaaa caacagtttc catttgttgc ctacacatta atttctgtat
     6181 tgtctatgta actggccgtt atcttttgtg tgcacatatc acaaatttag agaaacacca
     6241 caagtttatt ttaccccata acaaaatcaa caaactgtct tgtttcagta tcatactaaa
     6301 ccaagaatta attactgttt gggttggggg ggtccagaat atttcatgtt gattaaatta
     6361 gatgtagact ttgtaatgtg taacttgaag atatgtaatt tatgattaaa ttgtgtgtaa
     6421 atgttgtaat ataaactgtg gtaaatgtat aatttcatga gtaatgtttt ccaatgaatg
     6481 ttgataaaag ttttcctgtg tgtgactggc aggttaagta gcattttgag aatatattgt
     6541 tgttcccctt gtgaagctca ctaaattgta tatgatttgg tgtatagaat agcttaactt
     6601 ttaacatcta gagtctaatt agtgaaattt caaattaatt agtataattg tttttttttc
     6661 ctctttgtat ttgttagtgg ttccagggat ttgaggcatg ctggttttcc agatgcacaa
     6721 aaccctcaaa atattgatgg tggttgaaac tttattgaaa taagatcatg tatatgtatt
     6781 gatattgttg ttattattgt tgttaataaa aactctaaac ctggggaaga taaagaaacc
     6841 cagaatgaca aaatcagtgc ttccagtaga gttagactgc tgtttttcct ctaaacacac
     6901 gtattcaaaa tagaaaaaga aaagaaaaaa aaaagaattg tgaaagtgag aattgtttta
     6961 attatttatt cattttcttc cataactagt atagttatat tcatactcat acatacaaac
     7021 ttgaaaggag attaaaatcg agagttaatt tttcaaataa agaatgcatc agaaaactgg
     7081 atacttattt tattaatgga aatacaaact ctgaaattga gatctttttc tgataacaga
     7141 attactaggg aagcttatat ccttatgttt aataatttgt gaagtattga taccttccta
     7201 gaaatatagg aatgaacaga tatgcttttt tgccctttct aaatctggtt ttataatcag
     7261 acttagacag tgtttaggaa attaaatgac tgggcactct cttctggttt tataccacag
     7321 agatgttgaa tggaagcagg ctgagcaaag ccaaagaggc aaggggtgtg agcccagttc
     7381 ttctccccta tgcattccct ttcttagctt ccattaggta tagccttgga aaccagaaac
     7441 ttccatggct atagatttgg tgagatattt ctcatcacat tctaaattct ttctttgaat
     7501 ggatgggcag aactataggt ttataaagct catatgtgat tcttctgaaa agcaaaatat
     7561 gtcctcctag aactgcaaga tatctgtccc gatttatcat cagtcaaaaa tttttccctc
     7621 agaaaaagaa agatttgatt ttatttgaac ttatacagtg atatggcatt ttcatatgtt
     7681 tgccagactg gttattttat attgtggcca tattctgtta aaaggtgact attaattttc
     7741 tagctatagc tttaatatac acacttgtaa ttgtattcaa acactgtgta tctcatttgc
     7801 taaatacata tacattcatt tctcaaactt tttctccaag ttttaactaa tactgtgtca
     7861 gtgtattaaa gctaactttt acatatgata caaacaatgt aaacaattta gaggataaat
     7921 tttatgtagt ctcatttagt aatttaacat tttattttta gttacacaaa tttggttaga
     7981 aaatatattg ttaaatgatg agtggtattg tgcaatggtg acagtatgaa gagcttctgc
     8041 cttctcaaat taatgtttgt cacacacttt cattgaaatg gtaaaatagt agactaaata
     8101 gatcctatgt tgggcagtcc ttaaaattca atcatctcat atacaaaaga taactttcac
     8161 tcctgagtaa attacatgac atttacccct aagcatattc aaaattttct tgaaattttt
     8221 attaaggctt aatatagata tatataatat acatttataa agttgtgatt tcctttgtat
     8281 tcttctgatt tatgattcgt tatagttata gttgggtttt tttctttttg tttttgtaag
     8341 ccgggttctc attacattga agtgaaaatt tttctcacaa atgtagggta atatttttgg
     8401 tatttccaag tggcccaatt ggccaacata ctatgggagc agagcaagtg actatataca
     8461 gacagcgaca tttttataac atgtgccaat tatctcacta cagaatcttc gacaggaaag
     8521 ttaatatatt cgtccacagt agctttctta cagtaaccac caatgtgctt tccataaata
     8581 tgattgttat aagcactgca agtttacaac agtaagactg gaaaagaaaa ggctgctcat
     8641 aaaaatgtgt gtgcacaaat tataaaaaga aggcaattgt tttgtgattg tatatgataa
     8701 ttttaagaat aaaaattgtg aaatttatgc tgtccctgct taaaatattt gaaaaatttg
     8761 aactgtgtat ttatgtttgt attggggaag actcctcctc tgtgacatca tacagcttct
     8821 aaaagttaac agtatcccaa agtatgggat gctttggaag tgaaggactg gataattttt
     8881 ggaccagtat ggcagtatgt agtccagtgg caactgtgta ttaattgttc tatttcaggt
     8941 tctgtattgc atgttttctt attcataaat atagatatta ataaagtagt tatgagaaat
     9001 aa
//
