LOCUS       NM_183355               7163 bp    mRNA    linear   ROD 31-JUL-2024
DEFINITION  Mus musculus pre B cell leukemia homeobox 1 (Pbx1), transcript
            variant a, mRNA.
ACCESSION   NM_183355
VERSION     NM_183355.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7163)
  AUTHORS   Wang,F.C., Zhang,X.N., Wu,S.X., He,Z., Zhang,L.Y. and Yang,Q.E.
  TITLE     Loss of PBX1 function in Leydig cells causes testicular dysgenesis
            and male sterility
  JOURNAL   Cell Mol Life Sci 81 (1), 212 (2024)
   PUBMED   38724675
  REMARK    GeneRIF: Loss of PBX1 function in Leydig cells causes testicular
            dysgenesis and male sterility.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7163)
  AUTHORS   Ning,Y., Duo,S., Lin,X., Zhang,H., Fei,J., Zhang,B., Zeng,Y.,
            Xie,D., Chen,J., Liu,X. and Han,C.
  TITLE     Transcription factor PBX4 regulates limb development and
            haematopoiesis in mice
  JOURNAL   Cell Prolif 57 (5), e13580 (2024)
   PUBMED   38230761
REFERENCE   3  (bases 1 to 7163)
  AUTHORS   Choi,S.C., Park,Y.P., Roach,T., Jimenez,D., Fisher,A., Zadeh,M.,
            Ma,L., Sobel,E.S., Ge,Y., Mohamadzadeh,M. and Morel,L.
  TITLE     Lupus susceptibility gene Pbx1 controls the development, stability,
            and function of regulatory T cells via Rtkn2 expression
  JOURNAL   Sci Adv 10 (13), eadi4310 (2024)
   PUBMED   38536923
  REMARK    GeneRIF: Lupus susceptibility gene Pbx1 controls the development,
            stability, and function of regulatory T cells via Rtkn2 expression.
REFERENCE   4  (bases 1 to 7163)
  AUTHORS   Roach,T., Park,Y.P., Choi,S.C. and Morel,L.
  TITLE     Regulation of the STAT3 pathway by lupus susceptibility gene Pbx1
            in T cells
  JOURNAL   Mol Immunol 165, 1-10 (2024)
   PUBMED   38056350
  REMARK    GeneRIF: Regulation of the STAT3 pathway by lupus susceptibility
            gene Pbx1 in T cells.
REFERENCE   5  (bases 1 to 7163)
  AUTHORS   Cuda,C.M., Li,S., Liang,S., Yin,Y., Potula,H.H., Xu,Z.,
            Sengupta,M., Chen,Y., Butfiloski,E., Baker,H., Chang,L.J.,
            Dozmorov,I., Sobel,E.S. and Morel,L.
  TITLE     Pre-B cell leukemia homeobox 1 is associated with lupus
            susceptibility in mice and humans
  JOURNAL   J Immunol 188 (2), 604-614 (2012)
   PUBMED   22180614
  REMARK    GeneRIF: Pbx1 is a novel lupus susceptibility gene that regulates T
            cell activation and tolerance.
REFERENCE   6  (bases 1 to 7163)
  AUTHORS   Knoepfler,P.S. and Kamps,M.P.
  TITLE     The pentapeptide motif of Hox proteins is required for cooperative
            DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA
            binding by Pbx1
  JOURNAL   Mol Cell Biol 15 (10), 5811-5819 (1995)
   PUBMED   7565734
REFERENCE   7  (bases 1 to 7163)
  AUTHORS   Moskow,J.J., Bullrich,F., Huebner,K., Daar,I.O. and Buchberg,A.M.
  TITLE     Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in
            BXH-2 mice
  JOURNAL   Mol Cell Biol 15 (10), 5434-5443 (1995)
   PUBMED   7565694
REFERENCE   8  (bases 1 to 7163)
  AUTHORS   Kagawa,N., Ogo,A., Takahashi,Y., Iwamatsu,A. and Waterman,M.R.
  TITLE     A cAMP-regulatory sequence (CRS1) of CYP17 is a cellular target for
            the homeodomain protein Pbx1
  JOURNAL   J Biol Chem 269 (29), 18716-18719 (1994)
   PUBMED   7913464
REFERENCE   9  (bases 1 to 7163)
  AUTHORS   Monica,K., Galili,N., Nourse,J., Saltman,D. and Cleary,M.L.
  TITLE     PBX2 and PBX3, new homeobox genes with extensive homology to the
            human proto-oncogene PBX1
  JOURNAL   Mol Cell Biol 11 (12), 6149-6157 (1991)
   PUBMED   1682799
REFERENCE   10 (bases 1 to 7163)
  AUTHORS   Kamps,M.P., Murre,C., Sun,X.H. and Baltimore,D.
  TITLE     A new homeobox gene contributes the DNA binding domain of the
            t(1;19) translocation protein in pre-B ALL
  JOURNAL   Cell 60 (4), 547-555 (1990)
   PUBMED   1967983
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK144346.1, BC058390.1,
            AC116129.13 and AK083616.1.
            
            On Apr 19, 2014 this sequence version replaced NM_183355.2.
            
            Summary: This gene encodes a homeobox protein that belongs to the
            three-amino-acid loop extension/Pre-B cell leukemia transcription
            factor (TALE/PBX) family of proteins. The encoded protein is
            involved in several biological processes during embryogenesis
            including steroidogenesis, sexual development and the maintenance
            of hematopoietic stem cells. This protein functions in the
            development of several organ systems and plays a role in skeletal
            patterning and programming. Alternative splicing results in
            multiple transcript variants. [provided by RefSeq, Apr 2014].
            
            Transcript Variant: This variant (a) represents the longest
            transcript and encodes the longest isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058390.1, AF020196.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-272               AK144346.1         1-272
            273-2357            BC058390.1         1-2085
            2358-5477           AC116129.13        131279-134398       c
            5478-7163           AK083616.1         4-1689
FEATURES             Location/Qualifiers
     source          1..7163
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 75.95 cM"
     gene            1..7163
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /note="pre B cell leukemia homeobox 1"
                     /db_xref="GeneID:18514"
                     /db_xref="MGI:MGI:97495"
     exon            1..856
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             666..1958
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /note="isoform a is encoded by transcript variant a;
                     pre-B-cell leukemia transcription factor 1; homeobox
                     protein PBX1"
                     /codon_start=1
                     /product="pre-B-cell leukemia transcription factor 1
                     isoform a"
                     /protein_id="NP_899198.1"
                     /db_xref="CCDS:CCDS15461.1"
                     /db_xref="GeneID:18514"
                     /db_xref="MGI:MGI:97495"
                     /translation="MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIG
                     DILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTD
                     PQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQI
                     YHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQS
                     TCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGIT
                     VSQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGS
                     SSSFNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQ
                     MYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTSN"
     exon            857..930
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1175
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1366
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..1502
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..1662
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..1775
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1776..1865
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1866..7163
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7118..7123
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /note="hexamer: AATAAA"
     polyA_site      7146
                     /gene="Pbx1"
                     /gene_synonym="2310056B04Rik; D230003C07Rik; Pbx-1"
                     /note="major polyA site"
ORIGIN      
        1 ggagtcctga gcctgggcta aacaaaagca ggaggctgac ggggctgctg gagtttgcag
       61 agacacggag gaggaaagag cttgggcttt gcctgccgcc acggctgggg gtgatctggc
      121 ttctgctaca gcccaccccc tttgagatca ctctggcccg gagtgggggt ggggggcagc
      181 ggggggtggg ggggaaagtt tgcattgcaa tccccctgcc ttcctctcct ttctcccgat
      241 caatgcatat ttgcaaaagg attaagccac agatttaagc gccgggagcc catttctgcc
      301 ttgcaaagga gatcggactg aaaaacccaa aggcggctct gatttctttt cgccaagtgg
      361 gaaggtggtt tatttttctt gcttttttgg agtcaacacc cttccccacc agcccttatc
      421 cccaccctca ccccgcaacc ccttcacgcc cccctccccc tccccatcct cccaccatcc
      481 tctaaagagg caaagagatt ttttttttcc ccttttggtc ttcttcttct ttttttaaaa
      541 ccctggtccc tgtttatcct gaaaaggatt tgaagacagc ttgaaggata aaaagcctcg
      601 gtgcttccca ggcgccgatc cgaggagccg aagaggaaga gccggggctg ccggagcctt
      661 cagagatgga cgagcagccg aggctgatgc attcccacgc tggggtcggg atggccggac
      721 accccggcct gtcccagcac ttgcaggatg gggccggagg gaccgagggg gagggcggga
      781 ggaagcagga catcggggac attttacagc aaattatgac catcacagac cagagtttgg
      841 atgaagcgca ggccagaaaa catgctttaa actgccacag aatgaagcct gccttgttta
      901 atgtgttgtg tgaaatcaaa gaaaaaacag ttttgagtat tcggggagcc caagaagagg
      961 agcccacaga cccccagctc atgcgactgg acaacatgct gctagcagaa ggggtggcgg
     1021 ggcctgagaa gggcggaggc tcggcagcgg cggcggcggc agcggcagct tctgggggtg
     1081 caggttcaga caactcagtg gagcattccg actacagagc caaactctca cagatcagac
     1141 aaatctacca cacagagctg gagaagtatg agcaggcatg caatgaattc accacccacg
     1201 tgatgaacct ccttcgagag caaagccgga ccaggcccat ctctccgaag gagatcgagc
     1261 ggatggtgag catcatccac cgcaagttca gctccatcca gatgcagctg aaacagagca
     1321 cgtgcgaggc cgtcatgatc ctgcgctccc ggttcctgga tgcgaggcgg aagagacgga
     1381 atttcaacaa gcaagccaca gaaattctga atgaatattt ctattcccat ctcagcaacc
     1441 cttaccccag tgaggaagcc aaagaggagt tagccaagaa gtgcggcatc acagtctccc
     1501 aggtatcaaa ctggtttgga aataagcgaa tccggtacaa gaagaacata ggtaaatttc
     1561 aagaggaagc caatatttat gctgccaaaa cggctgtcac agccaccaat gtgtcagccc
     1621 atggaagcca agctaactcg ccctctactc ccaactcagc gggttcttcc agttctttta
     1681 acatgtcaaa ctctggagat ttgttcatga gcgtgcagtc actcaatggg gattcttacc
     1741 aaggggccca ggttggagcc aacgtgcaat cacaggtgga tacccttcgc catgttatca
     1801 gccagacagg aggatacagt gacggactcg cagccagtca gatgtacagt ccgcagggca
     1861 tcagtgctaa tggaggttgg caggatgcta ctaccccttc atcagtgacc tcccctacag
     1921 aaggccctgg cagtgttcac tctgatacct ccaactgatc tcccagcaat cgcatcccgg
     1981 ctgaccctgt gccgcagttg gggcagggcc aggagggagg gtttctctcc caacgctgaa
     2041 gcggtcagac tggaggtcga agcaatcagc aaacacaata agagtctcct tctcttctct
     2101 tctttgggat gctatttcag ccaatctgga cacttcttta tactctcttc cctttttttc
     2161 tgggtagaag ccacccttcc ctgcctccag ctgtcagact ggtttctgtc atcttccctg
     2221 gcccctgctc tctgttatag acgcccggtc cctgccctct atgacttcac tgaaggattt
     2281 ttttttcttc cacaattaga ggaatttaaa aaggaaaaac aaattacaaa gaaaacaata
     2341 aacgcatttg tatgttttca tgctggtggt ttgaggaggc aaatttacct cactaggagc
     2401 cctcatccct atgttgacag gcaatccttc tgtctccctt gttactctca ctacctctta
     2461 gcaggaatac accacactgc cctactcatt ccaagccact ctgtctccat tttccccttc
     2521 tttctgggaa caatcctgat tttttcctct tctttctggc cccaggtgtt ttttggggat
     2581 ggccataact gggcttctaa aggtgccaca tatcccaatg tagttccatc aggttgagtc
     2641 ctaggcagga agtctggcag gtaagggcac aaagaacagc aaaggcagag ctcctatcag
     2701 ctttctcatc ctcttagaaa cagctcttgg tcttagaggc acagtctatg aacatccaac
     2761 cattcaatgt tcagaacctc aggcaagcca ggtctaagag aggcatcctg atgagggtgt
     2821 ctataaagag tgaaggatct catcttgaaa ggctgcactg tcccttcata gacatacaca
     2881 cacataggta acacacaggt ggacacatgc acaaccttat agttttgctt ggcaggatgc
     2941 tagtaacctt tcatcagtga cttctgctac agaaggccct ggcagcgttc actctgatac
     3001 ctcccagatg gtctcccagc aatcaaatcc tgtacattag caagcatagt gctctacctg
     3061 gtgagcccaa gagaggagca gtatgtggct aaggcttcta ggacccacta acatgtactt
     3121 accacagtag gatgtgcagg acttcattaa catgggccag gattcaagag taaactgtct
     3181 tcattcctac cacctctgaa gctctcaggg agccacacac aggacttcct atatctatga
     3241 tggatttgga tgctttgttt gtgttttttt attatattat cttttcaaaa tactatagta
     3301 aaccatggtc ttcactctgg attcttcctc cagagaagag aatcatataa gtatatggtt
     3361 aacttttact aattaatttg aagacataag aatcatggag taaggatgat gaatttgttg
     3421 ttgttgttgt tgttgttgtt gttgttgttg ttgagatatc aacagtgatc tatctataat
     3481 gccaagggat cgacagaaaa tcagttacta gaaaggtagt cttgcttttg acatgagctt
     3541 aaattctcca gatggttctg ccagccataa agatggcagc tttgccagta gattaagtgg
     3601 caagtggtca gatatctttg gggcctcatg cacttcctct gtaaaatggg aattgttatc
     3661 catggctcac caagggtctt gtaagaggcc caagaaactg atcttgcttg tatttaatct
     3721 ccaggtctga tggtcaggga aggcagtctc cctataatga acatgtcatg ctaggtcaga
     3781 ataatacatg gttttcttgt tctaatttct acttgttctc agtaccttga tgccatcacc
     3841 atcatgagag tgtttcagag gctttctgct ctgatttggt tttggtctgt ttgtcttctt
     3901 aggatagaga agagattcaa aactagagga gtagaacctg gttttattag tttcaacttg
     3961 aatccagtta tgagaccttg caagtccttg tccctatgac aactcttctg cttcagggac
     4021 tcccaggaag aagtacaaga gcttgagggc tgagagacaa gcccacagtg ccaaacacat
     4081 tccacatgca gtgataaata ggagacatgc ttcatgtgtg tttggaggag ttgggcctgt
     4141 atacctggaa cctgggggac tgagtatttg aagataatgc agaacagaat tgtttggcaa
     4201 atgtaaattt gtccagctga ccccagtcac tagaaagact gtcatctaac ctctgccatg
     4261 ctcagaacgc gtgcctagaa gggacaatac aagtgtgtgt gtgtgtgtgt gtgtgtgtgt
     4321 gtgtgtgtgt gtgtggtagt gatgagaacc ggtgattttt gtctttgtgg caggaataca
     4381 ttgaaaccac tctcagaaca atggttggac cacatcattt tccataaagc acattataag
     4441 atttgctgaa gggttctctt ggaaacaaga gtgaccccag ctctggatgg aacacatgaa
     4501 gggacatgag tggatcaggc cacagcagtg ccaccctcac agaatgcttc tctctaggca
     4561 gtggctgtgc tgagaggccc acctacccag cacttcatta ggcctcctga aggttcaaca
     4621 tgtagccagc agtctgttct ccatgcccac tgtcacctcc aatgtggcag ccaccagatc
     4681 tctgtggtca agcaaggcta gggaaaactg gcagcctcca gatagaagtg gaaagagtgt
     4741 gcctctaaaa acttggctcc ctatgatttc aggtcaggtc aactttctag atcccaaaaa
     4801 atctgtgccc gagaattctt catagtcttt aagtacaagt gggagttctc tgtcttccac
     4861 aatagcaatt ctctctccct gagagatggt agcagacctt ggggttgcta ccgtatagct
     4921 tgtttatcat cgcctcttcc ccttagagta gaatggactt ctgggtagct gttgagccca
     4981 caggcacctt ctctccactt ccttccctgt ggtagtagta ttaattatta ttattttttt
     5041 attattattt tgattgcttt tgcccacacc tgtcttcact tctttcttcc tcctctttat
     5101 ttttttctgc ccagaaaaac ctgacttcga taccaaaaaa agataaaact acagaaactc
     5161 aaatttaaaa aaaaaagaaa aaaactctta gaaaaaaaaa aaagaaaaaa aagaaaaaaa
     5221 acctcaattc tttcagcttt attaacattt tccattgttt cttgcgaatt gtgtctcgtt
     5281 ctttgtagta ttgatgatga acatttgata atgaatgttc ttgtatattc agataaagaa
     5341 aaaaaaaaac caaaaaagcg gtctgaattt aatagtgttt ataataaaaa aaaatttaaa
     5401 aatgaccctc atagcacgca aaacaggaag gggaagtgtc ccttctttct gtgacaatac
     5461 acatcattcc tgcatacttt ttttttttaa caccaaacta cctatgttcc tcatttctcc
     5521 cgtttttctt tttaattttc ttgcatttgt gaattagttc aagaatgcta gaaaagtgtc
     5581 aaggtgtgta catccatttc ttctctcacg atgtttaaaa gtgaccgtac ttcattttgt
     5641 aaactaagaa aaaaaaaaaa gaaaaaaaaa agaaaaaagg aaaaaaaaaa aggttggaat
     5701 agtgtgaaca taataggttc aacctaacac atgtttatta attttgagac ccagaaatga
     5761 attcttctct ttattcctgc tcttaaaaat acaaaaaaag agaaagtttt gttttgtgtt
     5821 cttttttggt tttgtttatt tgaggggggg tgctcctttt ccgctgttgg gtttgtgggt
     5881 cttgctgggt ttattcttac gtatgtatac agggtgatgt gaaaagaggt acctgggaga
     5941 gaaggctgct tccatgctct gctttgcttc agtccatgtc aaaaccatcg agaaagctca
     6001 tggcctcatg tccctgcttt cttgcatgcc cggggtgtgt ggcactctgg tagtccctga
     6061 gataacaaga cagggacttc cttccttaaa tactcatctt ttcttatatt gaaaagaaag
     6121 gcttttgttg attctgattg tcccaaccaa gggttttctt tctccctgat taacttcaac
     6181 agtccacaag tatgcttcca acaagacagg atctttctcc aggcagaaaa gcactgctgt
     6241 ggagggcacc ataacccagt agagtagatc tgtgaagcag gccctgggcc catcttcttg
     6301 ggatccagag tccccgtatt ctgtgtgcag tgtgggtaaa gtgaggagcc tgggtcaagg
     6361 ctgcaattag aatgctaaga agctatcttt caattggtgc cacttgttgc taacctctgg
     6421 tgaggttaac tctttaaatt gccaggtggg cttcatcgga aagtctgtat tggtcatagg
     6481 ggaaaagaaa gccatgtggt tggacagact ttcagtttca gacattgctc attcaaacac
     6541 tcaggtgttc agaaagcaga cagaattcca accagatatg taaagaagac aagcgtgagt
     6601 agtggagctc tgctgtagga agcagtccac ctggagacag cttagctctt gtttctgtgt
     6661 cctaagagat gaaagagatg aaaggcaccc ttttcacgtc acctttgtgg ttttcagcct
     6721 agctcaaagc tttctggaaa cttttattat tttattttat tttattttat tttatttttg
     6781 taagctactt ctttcccttt cgttaaaata aataaaacat tgaatgtttt gccctctttc
     6841 tctctctttc ttcttccctt tgggggtttc cttttgaagt gtgttccttt ggttgttggt
     6901 tttatctccc cctcactttt tctccttatt attgagagta taaacctgca aagctcagct
     6961 ctactttggt tttgaaagtt gaagcttctc tgcttccgtg cgagcacagg cctctgtccc
     7021 cttcgattgc agcggaacga acgtttgtgt tctctaatga tactaacacg atgtaggttt
     7081 tacagtctcc taatttgtac tggtaatgca gattccaaat aaatagtttc ttttgttgca
     7141 aaaaaatata tatacacact tgt
//
