LOCUS       NM_029595               1256 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus phosphatidylethanolamine binding protein 2 (Pbp2),
            mRNA.
ACCESSION   NM_029595 XM_905825
VERSION     NM_029595.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1256)
  AUTHORS   Kazuki,Y., Kimura,M., Nishigaki,R., Kai,Y., Abe,S., Okita,C.,
            Shirayoshi,Y., Schulz,T.C., Tomizuka,K., Hanaoka,K., Inoue,T. and
            Oshimura,M.
  TITLE     Human chromosome 21q22.2-qter carries a gene(s) responsible for
            downregulation of mlc2a and PEBP in Down syndrome model mice
  JOURNAL   Biochem Biophys Res Commun 317 (2), 491-499 (2004)
   PUBMED   15063784
  REMARK    GeneRIF: Therefore, we suggest that Chr 21 gene(s) distal from the
            ETS2 locus reduce mouse mlc2a and PEBP expression in DS model mice
            and DS.
REFERENCE   2  (bases 1 to 1256)
  AUTHORS   Hickox,D.M., Gibbs,G., Morrison,J.R., Sebire,K., Edgar,K.,
            Keah,H.H., Alter,K., Loveland,K.L., Hearn,M.T., de Kretser,D.M. and
            O'Bryan,M.K.
  TITLE     Identification of a novel testis-specific member of the
            phosphatidylethanolamine binding protein family, pebp-2
  JOURNAL   Biol Reprod 67 (3), 917-927 (2002)
   PUBMED   12193403
  REMARK    GeneRIF: data show that phosphatidylethanolamine binding protein 2
            (pebp-2) is a testis-specific 21-kDa protein found within late
            meiotic and haploid germ cells and colocalizes with members of the
            MAP kinase pathway in late spermatocytes and spermatids(pebp-2)
REFERENCE   3  (bases 1 to 1256)
  AUTHORS   Simister,P.C., Banfield,M.J. and Brady,R.L.
  TITLE     The crystal structure of PEBP-2, a homologue of the PEBP/RKIP
            family
  JOURNAL   Acta Crystallogr D Biol Crystallogr 58 (Pt 6 Pt 2), 1077-1080
            (2002)
   PUBMED   12037323
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122820.4.
            
            On Mar 10, 2007 this sequence version replaced NM_029595.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK006258.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1256              AC122820.4         110253-111508
FEATURES             Location/Qualifiers
     source          1..1256
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 66.17 cM"
     gene            1..1256
                     /gene="Pbp2"
                     /gene_synonym="1700023A18Rik; Pebp-2; Pebp2"
                     /note="phosphatidylethanolamine binding protein 2"
                     /db_xref="GeneID:76400"
                     /db_xref="MGI:MGI:1923650"
     exon            1..1256
                     /gene="Pbp2"
                     /gene_synonym="1700023A18Rik; Pebp-2; Pebp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..601
                     /gene="Pbp2"
                     /gene_synonym="1700023A18Rik; Pebp-2; Pebp2"
                     /codon_start=1
                     /product="phosphatidylethanolamine-binding protein 2"
                     /protein_id="NP_083871.3"
                     /db_xref="CCDS:CCDS20646.1"
                     /db_xref="GeneID:76400"
                     /db_xref="MGI:MGI:1923650"
                     /translation="MPTDMSMWTGPLSLHEVDEQPQHLLRVTYTEAEVEELGQVLTPT
                     QVKHRPGSISWDGLDTGKLYTLILTDPDAPSRKKPVYREWHHFLVVNMKGNDISSGNV
                     LSDYVGSGPPKGTGLHRYVWLVYQQDKPLRCDEPILTNRSGDHRGKFKTAAFRKKYHL
                     GAPVAGTCYQAEWDSYVPKLYKQLSGK"
     regulatory      1229..1234
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pbp2"
                     /gene_synonym="1700023A18Rik; Pebp-2; Pebp2"
                     /note="hexamer: ATTAAA"
     polyA_site      1251
                     /gene="Pbp2"
                     /gene_synonym="1700023A18Rik; Pebp-2; Pebp2"
                     /note="major polyA site"
ORIGIN      
        1 cttcagcagc acccaaccgc cactccagcc tctcaccatg cctacagaca tgagcatgtg
       61 gaccgggccg ctgagcctcc acgaagtgga tgagcagccc cagcacctac tgcgggtcac
      121 ctacaccgag gcggaggtgg aagagctggg ccaagtgctg acgcccaccc aggttaagca
      181 cagacccgga agcatttcat gggatggcct tgacacaggg aaactctaca ccttgatcct
      241 cacagacccg gatgctccca gtaggaagaa acccgtgtac agggaatggc accattttct
      301 ggtggtcaac atgaaaggca atgacatcag cagtgggaac gtcctctcgg attacgtggg
      361 ttccggacct cccaagggca ctggcctcca tcgctatgtc tggctggtgt accagcagga
      421 caagccactg agatgtgacg aacccatcct caccaaccgg tctggagacc atcgtgggaa
      481 gttcaaaact gcagccttcc gcaagaagta tcacctggga gccccggtgg ccggcacgtg
      541 ttaccaggca gaatgggaca gctatgtacc aaagctgtac aaacagctgt ctgggaaata
      601 ggaggatctc ttgatgatca tggccactcc tgccatatta ttatcgggtt cagcaatgag
      661 tggcatgtct ttccttttcc cattcccacc tgcccaaggg attcttgagc tgttgtaggg
      721 aggtagttta ggatgacttt ttctcaccct aaagattcca aatagttgca cccagttggt
      781 tttgatcaaa cttaagctcc atctggtgga gatttggcac tgtgatggac tcgttatatt
      841 ggtaataaaa gaacagtaac tctgaaagta aagaaggcaa aatccaaggg aaaagaccag
      901 gcctacagga agaaagcaag gactggcctc tgcctctgtt ctgaatcagg agctgtgctc
      961 agtggttcca gttctcagag ttgtctgaag gtcctgtctc ccacctgcac aaccagagac
     1021 ttagtatctg ggtgatccta ggcatacagc tggacaagta tctgtgtctt atgcctccat
     1081 taaagagcag agctctgtta agaagcaatc aggaagacac ctctgctgtg tgctggcttg
     1141 gcatgagccc ggatgcagtc ctgaacaaaa atagttattc tgggagttgt ttacattaat
     1201 tctgtttgct tattgtcaaa ttaaaaaaat taaagcagaa aacaaactat atgatg
//
