LOCUS       NM_026701               2395 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus phenazine biosynthesis-like protein domain containing
            1 (Pbld1), transcript variant 2, mRNA.
ACCESSION   NM_026701
VERSION     NM_026701.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2395)
  AUTHORS   Platt,R.J., Zhou,Y., Slaymaker,I.M., Shetty,A.S., Weisbach,N.R.,
            Kim,J.A., Sharma,J., Desai,M., Sood,S., Kempton,H.R.,
            Crabtree,G.R., Feng,G. and Zhang,F.
  TITLE     Chd8 Mutation Leads to Autistic-like Behaviors and Impaired
            Striatal Circuits
  JOURNAL   Cell Rep 19 (2), 335-350 (2017)
   PUBMED   28402856
REFERENCE   3  (bases 1 to 2395)
  AUTHORS   Ghiasvand,N.M., Rudolph,D.D., Mashayekhi,M., Brzezinski,J.A. 4th,
            Goldman,D. and Glaser,T.
  TITLE     Deletion of a remote enhancer near ATOH7 disrupts retinal
            neurogenesis, causing NCRNA disease
  JOURNAL   Nat Neurosci 14 (5), 578-586 (2011)
   PUBMED   21441919
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK143947.1 and AC113107.15.
            
            On Jan 13, 2018 this sequence version replaced NM_026701.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143947.1, BC019997.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1265              AK143947.1         9-1273
            1266-1266           AC113107.15        186279-186279
            1267-2395           AK143947.1         1275-2403
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 32.53 cM"
     gene            1..2395
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /note="phenazine biosynthesis-like protein domain
                     containing 1"
                     /db_xref="GeneID:68371"
                     /db_xref="MGI:MGI:1915621"
     exon            1..113
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..896
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /note="isoform 1 is encoded by transcript variant 2; MAWD
                     binding protein homolog 1; phenazine biosynthesis-like
                     domain-containing protein 1"
                     /codon_start=1
                     /product="phenazine biosynthesis-like domain-containing
                     protein 1 isoform 1"
                     /protein_id="NP_080977.2"
                     /db_xref="CCDS:CCDS23895.1"
                     /db_xref="GeneID:68371"
                     /db_xref="MGI:MGI:1915621"
                     /translation="MKLPIFIADAFTATAFRGNPAAVCLLERTLEEDAHQQIAREMNL
                     SETAFIRKLQPTDSFTQSSRFGLRWFTPVSEVPLCGHATLASAAVLFHKIQNRNSTLT
                     FVTMSGELKARRAEDGIVLDFPVYPTFPQDFHEVEDLIKAAIGDTLVQDIRYSTDTRK
                     LLVRLSDSYDRSFLESLKVNTEPLPAIEKTGKVRGLILTVKGEPGGQTAPYDFYSRYF
                     APWVGIAEDPVTGSAHTVLSSYWSQQLRKKEMRAFQCSRRGGELDISLRPDGRVDIKG
                     GAVIVLEGTLTA"
     exon            114..213
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /inference="alignment:Splign:2.1.0"
     exon            214..312
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /inference="alignment:Splign:2.1.0"
     exon            313..422
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /inference="alignment:Splign:2.1.0"
     exon            423..452
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /inference="alignment:Splign:2.1.0"
     exon            453..541
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /inference="alignment:Splign:2.1.0"
     exon            542..720
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /inference="alignment:Splign:2.1.0"
     exon            721..783
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /inference="alignment:Splign:2.1.0"
     exon            784..2395
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2324..2329
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /note="hexamer: AATAAT"
     polyA_site      2350
                     /gene="Pbld1"
                     /gene_synonym="0610038K03Rik; Mawbp; Pbld"
                     /note="major polyA site"
ORIGIN      
        1 ggagccctca gacaaagcca gcgaggaaaa tgaagctccc aatcttcata gcagatgcgt
       61 tcactgcgac agctttccgg ggcaatcctg ccgcagtctg cctcctggag cgcacattgg
      121 aggaagacgc ccatcagcaa attgcgaggg agatgaacct ctcagaaacg gctttcatca
      181 ggaaactgca gccgactgac agcttcacac aaagctctcg ctttggactg agatggttta
      241 cgccagtgag tgaagtcccc ttgtgcggcc acgccacact ggcctctgcg gctgtgctgt
      301 ttcacaaaat acagaacagg aacagcaccc tgacctttgt cacaatgagc ggggagctaa
      361 aggccagaag agcagaagat gggatagtcc tggactttcc tgtctaccca acctttcccc
      421 aggacttcca tgaagttgaa gacttgataa aggcagccat aggtgacacc ctggtccagg
      481 acatccggta ctctacagat accagaaaac tcctggtccg gctcagcgat tcttatgaca
      541 ggtcctttct agagagcctg aaggtgaaca cagagcctct gcctgcaatt gagaagacag
      601 ggaaggtgag aggcctcatc ctcactgtca aaggagagcc tggggggcag acggccccgt
      661 atgacttcta ctccagatac ttcgcgccgt gggttggtat tgctgaagac ccggtgacag
      721 gatctgcaca caccgttctc agcagttact ggtcccagca gctcaggaag aaagagatgc
      781 gagcctttca gtgttcccgc cgaggagggg agctggacat ttccctgcga cctgatgggc
      841 gcgttgacat aaagggcgga gctgttattg tcttggaggg cacgctgacc gcctagagat
      901 gctcctgctg ggcttggggc cactgttcca caagtgtctt ctctagagcc cagaacccga
      961 cccaacccaa ctcaacagca gatgcacaga gcttggttca gtcgtcgtgt gaacccaaaa
     1021 gggaagacac ctgatggagg tgcggtagtg tctccagaat cctttcccga tggtgggctc
     1081 tgaactctgc ctgtgtgtgc atcttcagtc cccacagcag atagggatgc tgccccttct
     1141 tttgatcatg actgccaatc aaagtgagag gtgcactgat aaggagccag agaatgccat
     1201 ttcaattgag gtatgggtac cttagggcat ttcacagccc tttagaagaa taaataggtg
     1261 tgtagaatgt tgtgttgcca aaaaacattt tctctccgcc ccctaaggtt ccaaagacca
     1321 accaaggcac accaccacca aagctcccct agggcaccaa tgagttatca gacttcttta
     1381 cagagcagag gtgaaggttt ccttacagcg gtgtgggttc catcccctaa aatgtggcac
     1441 cagaagggct tttacatagc atcaatggtg accttcctat agtggcacag atggagccca
     1501 gctcccctaa tctctgctgg cctgtgtcct ccagcctctt tgaggccatg tgcaattagg
     1561 gcaatgttgc atacatagga ggtagtgagt ggctgggttc tcagaggagg ccccgtgatc
     1621 tccccatccc tctatgagga gatgtaaaca gtcgccagac ccagctggca tgatctttgg
     1681 caagtgcgca cagctgaact cctgaagatg gaagttgctt ggctcagggt atggtcctga
     1741 gcaacatgca aaagtccatc tcctgatgta ataatactag gaaagatgag ggggctggtg
     1801 agatggctca gtgggtaaga gcacccgact gctcttccga aggtccgaag ttcaaatccc
     1861 agcaaccaca tggtggctca caaccatctg taacatgatc tgactccctc ttctggagtg
     1921 tctgaagaca gctacagtgt acttacatat aataaataaa taaatcttta aaaaaaaaaa
     1981 tactaggaaa gatgagtaga ctgaaaactg ttggaggctg tgctgcaggg ctggggtacg
     2041 taggaccgta tgggctgtga ggtcagcaaa atgaaacagt tcatgctggg ggacaacgta
     2101 gagtaatttc aatgagctaa aaaaaaaaga gttgggggct tgctgagtgg ctgaaacgct
     2161 tgctgccaag gctgacaccc tgagttcgaa tcctgggacc catatggtag aagcagagat
     2221 ccaactccta catgctgtcc tctgacctac gtacacatag gtgctatagc atgcacacat
     2281 ccacacctat acatgcatac cccaaacaaa taaatgtaat aaaaataatt ttcttttttt
     2341 tttcacttta tatgttggat gtcatctgtt gtaattatta aaaaacaatc tactc
//
