LOCUS       NM_011039               5288 bp    mRNA    linear   ROD 25-FEB-2025
DEFINITION  Mus musculus paired box 7 (Pax7), mRNA.
ACCESSION   NM_011039
VERSION     NM_011039.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5288)
  AUTHORS   Pryce,B.R., Oles,A., Talbert,E.E., Romeo,M.J., Vaena,S., Sharma,S.,
            Spadafora,V., Tolliver,L., Mahvi,D.A., Morgan,K.A., Lancaster,W.P.,
            Beal,E., Koren,N., Watts,B., Overstreet,M., Berto,S.,
            Subramanian,S., Calisir,K., Crawford,A., Neelon,B., Ostrowski,M.C.,
            Zimmers,T.A., Tidball,J.G., Wang,D.J. and Guttridge,D.C.
  TITLE     Muscle inflammation is regulated by NF-kappaB from multiple cells
            to control distinct states of wasting in cancer cachexia
  JOURNAL   Cell Rep 43 (11), 114925 (2024)
   PUBMED   39475511
REFERENCE   2  (bases 1 to 5288)
  AUTHORS   Lu,Y., Walji,T., Ravaux,B., Pandey,P., Yang,C., Li,B.,
            Luvsanjav,D., Lam,K.H., Zhang,R., Luo,Z., Zhou,C., Habela,C.W.,
            Snapper,S.B., Li,R., Goldhamer,D.J., Schmidtke,D.W., Pan,D.,
            Svitkina,T.M. and Chen,E.H.
  TITLE     Spatiotemporal coordination of actin regulators generates invasive
            protrusions in cell-cell fusion
  JOURNAL   Nat Cell Biol 26 (11), 1860-1877 (2024)
   PUBMED   39487253
REFERENCE   3  (bases 1 to 5288)
  AUTHORS   Dudukcu,O., Raj,D.D.A., van de Haar,L.L., Grossouw,L.M.,
            Linders,L.E., Garritsen,O., Adolfs,Y., van Kronenburg,N.C.H.,
            Broekhoven,M.H., Kapteijns,T.H.W., Meye,F.J. and Pasterkamp,R.J.
  TITLE     Molecular diversity and migration of GABAergic neurons in the
            developing ventral midbrain
  JOURNAL   iScience 27 (11), 111239 (2024)
   PUBMED   39569362
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5288)
  AUTHORS   Cai,S. and Yin,N.
  TITLE     Single-cell transcriptome and chromatin accessibility mapping of
            upper lip and primary palate fusion
  JOURNAL   J Cell Mol Med 28 (19), e70128 (2024)
   PUBMED   39392189
REFERENCE   5  (bases 1 to 5288)
  AUTHORS   Zhou,D., Shi,Y., Zhang,D., Zuo,J., Zeng,C., Mamtawla,G., Huang,L.,
            Gao,X., Zhang,L. and Wang,X.
  TITLE     Liver-secreted FGF21 induces sarcopenia by inhibiting satellite
            cell myogenesis via klotho beta in decompensated cirrhosis
  JOURNAL   Redox Biol 76, 103333 (2024)
   PUBMED   39226764
REFERENCE   6  (bases 1 to 5288)
  AUTHORS   Hill,R.E. and Hanson,I.M.
  TITLE     Molecular genetics of the Pax gene family
  JOURNAL   Curr Opin Cell Biol 4 (6), 967-972 (1992)
   PUBMED   1485966
  REMARK    Review article
REFERENCE   7  (bases 1 to 5288)
  AUTHORS   Weydert,A., Cloez-Tayarani,I., Fillion,M.P., Simon-Chazottes,D.,
            Guenet,J.L. and Fillion,G.
  TITLE     Molecular cloning of two partial serotonin 5-HT1D receptor
            sequences in mouse and one in guinea pig
  JOURNAL   C R Acad Sci III 314 (10), 429-435 (1992)
   PUBMED   1521164
REFERENCE   8  (bases 1 to 5288)
  AUTHORS   Le Roy,H., Simon-Chazottes,D., Montagutelli,X. and Guenet,J.L.
  TITLE     A set of anonymous DNA clones as markers for mouse gene mapping
  JOURNAL   Mamm Genome 3 (4), 244-246 (1992)
   PUBMED   1351769
REFERENCE   9  (bases 1 to 5288)
  AUTHORS   Walther,C., Guenet,J.L., Simon,D., Deutsch,U., Jostes,B.,
            Goulding,M.D., Plachov,D., Balling,R. and Gruss,P.
  TITLE     Pax: a murine multigene family of paired box-containing genes
  JOURNAL   Genomics 11 (2), 424-434 (1991)
   PUBMED   1685142
REFERENCE   10 (bases 1 to 5288)
  AUTHORS   Jostes,B., Walther,C. and Gruss,P.
  TITLE     The murine paired box gene, Pax7, is expressed specifically during
            the development of the nervous and muscular system
  JOURNAL   Mech Dev 33 (1), 27-37 (1990)
   PUBMED   1982921
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL844480.29 and AL831790.3.
            
            On Sep 13, 2022 this sequence version replaced NM_011039.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13948564.4795858.1,
                                           SRR7345562.3222161.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849375,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-120               AL844480.29        12043-12162         c
            121-356             AL844480.29        9354-9589           c
            357-486             AL844480.29        8713-8842           c
            487-615             AL844480.29        7792-7920           c
            616-815             AL831790.3         167773-167972       c
            816-981             AL831790.3         164051-164216       c
            982-1184            AL831790.3         162866-163068       c
            1185-1431           AL831790.3         132222-132468       c
            1432-5288           AL831790.3         120336-124192       c
FEATURES             Location/Qualifiers
     source          1..5288
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 70.83 cM"
     gene            1..5288
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /note="paired box 7"
                     /db_xref="GeneID:18509"
                     /db_xref="MGI:MGI:97491"
     exon            1..120
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..1547
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /note="paired box transcription factor PAX7; paired box
                     gene 7"
                     /codon_start=1
                     /product="paired box protein Pax-7"
                     /protein_id="NP_035169.1"
                     /db_xref="CCDS:CCDS18850.1"
                     /db_xref="GeneID:18509"
                     /db_xref="MGI:MGI:97491"
                     /translation="MAALPGAVPRMMRPGPGQNYPRTGFPLEVSTPLGQGRVNQLGGV
                     FINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIG
                     GSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRI
                     KFGKKEDDEEGDKKEEDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRS
                     RTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGA
                     NQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQ
                     GGLAAAAAAADTSSAYGARHSFSSYSDSFMNPGAPSNHMNPVSNGLSPQVMSILSNPS
                     AVPPQPQADFSISPLHGGLDSASSISASCSQRADSIKPGDSLPTSQSYCPPTYSTTGY
                     SVDPVAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY"
     exon            121..356
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /inference="alignment:Splign:2.1.0"
     exon            357..486
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /inference="alignment:Splign:2.1.0"
     exon            487..615
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /inference="alignment:Splign:2.1.0"
     exon            616..815
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /inference="alignment:Splign:2.1.0"
     exon            816..981
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /inference="alignment:Splign:2.1.0"
     exon            982..1184
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1431
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..5288
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5253..5258
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /note="hexamer: ATTAAA"
     regulatory      5263..5268
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /note="hexamer: ATTAAA"
     polyA_site      5275
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /note="major polyA site"
     polyA_site      5288
                     /gene="Pax7"
                     /gene_synonym="Pax-7"
                     /note="major polyA site"
ORIGIN      
        1 agccgactct ggattcgtct ccagcgtgcg caggaatggc ggcgctgccc ggcgcggtcc
       61 ccaggatgat gagacccggc ccggggcaga actacccgcg caccggcttc cccctggaag
      121 tgtccacccc tcttggccaa ggccgggtca atcagcttgg tggggtcttc atcaacggtc
      181 gacccctgcc gaaccacatc cgtcacaaga tagtggaaat ggcccaccat ggcatccggc
      241 cctgcgtcat ctcccgtcag ctccgtgttt cccatggttg tgtctccaag attctgtgcc
      301 gatatcagga gactgggtcc atccggcccg gggctatcgg aggcagcaag cccagacagg
      361 tggcgactcc ggatgtggag aaaaagattg aggagtataa gagagagaac cccgggatgt
      421 tcagctggga aatccgggac cggctgctga aggacggtca ctgcgaccga agcacggtgc
      481 cctcagtgag ttcgattagc cgagtgctca gaatcaagtt cgggaagaaa gaggacgacg
      541 aggaaggaga caagaaagaa gaagatggcg agaagaaagc caaacacagc atcgatggca
      601 tcctgggcga caaagggaac cgtctggatg agggctcaga tgtggaatca gaacccgacc
      661 tccccctgaa gcgcaagcag cgccgcagtc ggaccacgtt cacagccgag cagctggagg
      721 agctggagaa ggccttcgag aggacccact acccggacat ctacacccgg gaggagctgg
      781 cacagaggac caagctcacg gaggcacgcg tccaggtctg gttcagtaac cggcgtgccc
      841 gctggcgtaa gcaggcagga gctaaccagc tggccgcctt caaccacctt ctgccgggag
      901 gtttcccacc caccggcatg cccacgctgc caccctacca gctgccggac tctacctacc
      961 ccaccaccac catctcccaa gatggaggca gcacagtaca caggccccag ccccttccgc
     1021 catcaaccat gcatcagggt gggctggctg cggccgctgc agcagcggac accagctctg
     1081 cctacggagc ccgccacagc ttctccagct actctgacag cttcatgaac cctggggctc
     1141 cctccaacca catgaaccct gtcagcaatg gcctgtctcc tcaggtcatg agcatcctta
     1201 gcaacccgag tgccgtgcct ccacagcccc aggccgactt ctccatctcc ccgctgcatg
     1261 gaggcctgga ctcggcttcc tccatctcag ccagctgcag ccaacgggcc gactccatca
     1321 agccaggaga cagcttgccc acgtcccagt cttactgccc acccacctac agcaccactg
     1381 gctacagtgt ggaccctgtg gctggctacc agtacagcca gtatggccaa actgctgttg
     1441 attacctggc caaaaacgtg agcctgtcca cacagcgccg tatgaagctt ggggaacact
     1501 ccgctgtgct gggacttctt cctgtggaaa cgggacaagc ctactagggt ccctggggca
     1561 acttgcccca tccagtggcc cagccaaccc ttcccaagcc ctgagtctcc tcacctcagt
     1621 ccccttatcc ccctggggtt gcaggagacc aagggaaaaa aaccctttcc cttcctacag
     1681 gaaaccctct ggagacggaa aaccagtgtg ccatctaccc atgcttagtg acccagagtg
     1741 gccccttgcc ttcccctctt tcttcagagg ggttcctagg catcctgcag tgacctccag
     1801 ctcacatcca ccttctctgt atcgtggcct cggtcctgtc tcagtgcaga gattgaggct
     1861 caatttgaac caagcaccta gttatcagaa gaaaatggtg ccaaagacaa ggccctggag
     1921 tccttgacct ctgagtcgtg ggtgccctgg ctatgggtgt aggtggagcc catgggtgtc
     1981 ctcagtcaca gagctgggag ctctctctcg ctcgcttggc atcaggactg cagcctcttt
     2041 cactggacac tgagatgagt ccccagggtg ttcccagggg agaaagcagg taacatccca
     2101 gctttaccta ggaatccaga ggactttagg actgtcccta tgcaccctgc agggcatcag
     2161 gagaccagga agggattcta gcagagggta gggggcacag aggcagagct gattgcccat
     2221 gggctatccc agaatgcctg gtcctgaatc tagcatcagg aggtgcagga ttcctaggct
     2281 gcaatctgac agaggcttgc ccactgtgtc aggcctgggc agcccacaga acctgtcact
     2341 ctcctcaatt ggtaggagaa gaggtcttga ggtgacagga ggcagaaggc aggctcagac
     2401 agtcagagag caccaagctt tcaagtccgc acccctgggg ttcggcatac catcttgctg
     2461 gcagctggaa acctggttcc ctgaaagggg gcctccatcc tccagaatgt aaggctcttg
     2521 atgccaccgg atgcagagag ccttctcggg ccagacaaaa ttgctgctcc accccagaga
     2581 agatgttcca gccttcttgg catcttagag gaaggccatg tcgctgtcct tttcagagta
     2641 gcatattttt cagtgatggc tgctcagtca ggaggcttct gtcgccttac aaagcacagt
     2701 gcgctctggg cactgtttct aagccacccc atcccacccc cacccccgcc accccgggga
     2761 cagaggaaga tgctaaaagt cccagcaaag aggacaaagc acctttctta agcactccag
     2821 agtcttcctt gtaccccgcc ctctcttaga gctgggtctt ttgagggaaa cggattgctg
     2881 agccctcccc cccccccaat cctctcctct gtggagctgt ttatcatcct ctatttatca
     2941 aaatcgcatc catctttacc ctctccttcg ctatagccta cttctggatc accctcatcc
     3001 agtgctggta ccccacagca ctaaatccag gaaccctggg cttgatcacc tgttgccacc
     3061 tgtacacatg aaaccacctg ctggcccggc ccatgtctcc tgccctcagc cagcaagaca
     3121 ttcctagaga gaggaactat gggcttaaaa gccccaactg acttcctttt gcctggggac
     3181 ctgaaccgac aagacaccag ggacacttgt ctacatgaac atgtgaccaa tgtacaccga
     3241 tttctcatct ctagacctat tatctgaagc ctgtcccggg ccatgactag aatggcttgt
     3301 atctgtggtt tagagaagtc taataataac tgagggcaaa ctgactctct ggtagcatgg
     3361 agcaccaggc ggatggagct caccagctct gtccaggttt caaaggagga gactgttggg
     3421 ctcttcaagg tctggacaag aggaaagcca cattgccccc ttgggaaccc aggttctcct
     3481 tttgaacttc tcacagctgc aagcacccct ttcaaagacc aaatgcatcc tcctccacat
     3541 tccttgctcc ctggaggcct ggctctggat acacctgagt cttcgttcac ctactacact
     3601 ttaggagcag gaacttcaag caggtgacat ccacagggcc cagtcccagc caagggagca
     3661 acattccaac gcttggacca atcataatga tctgcccgtg agggtaaccg caactagaga
     3721 cctgcttggg agaaaacaaa atgacttctc attccatgcc atgcctctga atgctccccc
     3781 aagctgccat cttggtataa aatgggactt gtgttgtggg gaaccccttg accccaacag
     3841 gttttcccaa ctgtctcatg cttttgtgaa tctgtctgct ttgatctgta aaactcagcc
     3901 ttgtttgggc agcttgtaat ttcaacagtg aggcgacatc gattagatga gaggcaccag
     3961 gcctctccgc cgccgtccct ctgtggccgt ccctctgggg ttgagcagaa cctagaagaa
     4021 ggccgatttc cagtggccag actggaccag aaacagcccc caccccaatc cctgtaaata
     4081 gagtcaatag caaaataaga ggggcgccct ccatgtcacc tcaagtagct actggttctt
     4141 ctgtggaggc ccctctgaac tcattgtctg gtagttgaaa atgtgatgtt gtgctgtttg
     4201 tttatagaac attggctttt tatatataaa tctatatact taaaaacaaa aacaaaaaca
     4261 aaaaaaatgg aaagaaaccc ccacagtttg tgtcgtgcta gtgccgggga ccatctgtag
     4321 ggatctcatt gtgtgtttgg attatgtatg ccagcctttc tcgggttcct ccttcttttt
     4381 ttttttcttt gtcatttccc tactcccgat ttggtttttc tctctcgctc tgaaaatgaa
     4441 agagatggct tgaagagcca agctcctact cctttacttt ataggcgaat taactttgcc
     4501 cttcttttag gggaccagga acaagcacag gaaacagaaa ttaggaagca agagggtagg
     4561 agagaagagt gaggggagga gctagccagg gagacaggag agcagggtgg tttcgcagcc
     4621 agatgatggc tgtggcccag gacggagcct ggattagcat gctccaccag aggctggtat
     4681 tgttttgcat ggaaatggta gaatgttctc agacatggag ctaagccttg ctgagggact
     4741 ccacagtagc caactaagaa gactccttta agaggctcca attctcccca ggatcttgga
     4801 aatgtctctc cctgcaggat gcttctcttg ggtacacaag catcctcgcc ttctataaaa
     4861 gcaccaagcc aagaccaaat ggagggtatg tgggctgccg tgttgaaatg tgtcaagata
     4921 cctgtgcatt taatgtctct tctgtctgta cggacatggg cagccccctg ctgggaaaag
     4981 gccaccctgt gctgacgaac attccttctt cccagtgact gcaacattgt tgcttcagtg
     5041 tttggctcag ccatttctcc tccacgcaaa gtgagtgtgt gtgcatgagg ggtgtgagtg
     5101 ggatgtgtgc gtgtgggcgg gcgtctaaat ataaccgcac cataatttat tcagctatat
     5161 ggagtagtag actagaaaga caaactggta tttgctttaa ctacctgctg cttgtaagcg
     5221 ctgcctctgt aactcaggcg taactgttat acattaaaag aaattaaaaa catcatgaag
     5281 attctgca
//
