LOCUS       NM_001033421            2215 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus prostate and testis expressed 2 (Pate2), mRNA.
ACCESSION   NM_001033421
VERSION     NM_001033421.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2215)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2215)
  AUTHORS   Noda,T., Sakurai,N., Nozawa,K., Kobayashi,S., Devlin,D.J.,
            Matzuk,M.M. and Ikawa,M.
  TITLE     Nine genes abundantly expressed in the epididymis are not essential
            for male fecundity in mice
  JOURNAL   Andrology 7 (5), 644-653 (2019)
   PUBMED   30927342
REFERENCE   3  (bases 1 to 2215)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   4  (bases 1 to 2215)
  AUTHORS   Loughner,C.L., Bruford,E.A., McAndrews,M.S., Delp,E.E.,
            Swamynathan,S. and Swamynathan,S.K.
  TITLE     Organization, evolution and functions of the human and mouse
            Ly6/uPAR family genes
  JOURNAL   Hum Genomics 10, 10 (2016)
   PUBMED   27098205
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2215)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 2215)
  AUTHORS   Levitin,F., Weiss,M., Hahn,Y., Stern,O., Papke,R.L., Matusik,R.,
            Nandana,S.R., Ziv,R., Pichinuk,E., Salame,S., Bera,T., Vincent,J.,
            Lee,B., Pastan,I. and Wreschner,D.H.
  TITLE     PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR
            proteins that are expressed in reproductive and neuron-rich tissues
            and possess neuromodulatory activity
  JOURNAL   J Biol Chem 283 (24), 16928-16939 (2008)
   PUBMED   18387948
REFERENCE   7  (bases 1 to 2215)
  AUTHORS   Kaplan,N., Morpurgo,N. and Linial,M.
  TITLE     Novel families of toxin-like peptides in insects and mammals: a
            computational approach
  JOURNAL   J Mol Biol 369 (2), 553-566 (2007)
   PUBMED   17433819
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113081.8.
            
            On Nov 5, 2009 this sequence version replaced NM_001033421.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK136651.1, BY721028.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-96                AC113081.8         176656-176751       c
            97-120              AC113081.8         176488-176511       c
            121-252             AC113081.8         175780-175911       c
            253-2215            AC113081.8         173501-175463       c
FEATURES             Location/Qualifiers
     source          1..2215
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 20.32 cM"
     gene            1..2215
                     /gene="Pate2"
                     /gene_synonym="Gm846; mANLP1; Pate-M"
                     /note="prostate and testis expressed 2"
                     /db_xref="GeneID:330921"
                     /db_xref="MGI:MGI:2685692"
     exon            1..96
                     /gene="Pate2"
                     /gene_synonym="Gm846; mANLP1; Pate-M"
                     /inference="alignment:Splign:2.1.0"
     exon            97..120
                     /gene="Pate2"
                     /gene_synonym="Gm846; mANLP1; Pate-M"
                     /inference="alignment:Splign:2.1.0"
     exon            121..252
                     /gene="Pate2"
                     /gene_synonym="Gm846; mANLP1; Pate-M"
                     /inference="alignment:Splign:2.1.0"
     exon            253..2215
                     /gene="Pate2"
                     /gene_synonym="Gm846; mANLP1; Pate-M"
                     /inference="alignment:Splign:2.1.0"
     regulatory      722..727
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pate2"
                     /gene_synonym="Gm846; mANLP1; Pate-M"
                     /note="hexamer: AATATA"
     polyA_site      746
                     /gene="Pate2"
                     /gene_synonym="Gm846; mANLP1; Pate-M"
                     /note="major polyA site"
     regulatory      929..934
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pate2"
                     /gene_synonym="Gm846; mANLP1; Pate-M"
                     /note="hexamer: ATTAAA"
     polyA_site      949
                     /gene="Pate2"
                     /gene_synonym="Gm846; mANLP1; Pate-M"
ORIGIN      
        1 gagaaaagag ccagtacctt cctcagaaag ctgctgaaga caagggttgc aggatgtttg
       61 tgctggtgat gatctgtctg ttctgccaat attggggtgt ccttaatgag cttgaagaag
      121 aagatcgtgg actactgtgt tataaatgta agaaatatca tcttgggtta tgctatggaa
      181 tcatgacatc ctgcgtacca aatcatagac agacctgcgc tgctgagaac ttttacatac
      241 tcacaaaaaa agggcagagt atgtatcatt attcaagact gtcatgtatg accaactgtg
      301 aggacatcaa cttcctgagt tttgaaagga ggacagagct catttgttgt aagcacagta
      361 actattgcaa cctcccaatg ggactctagt tctgaattta ttatggattt ggtatcattc
      421 ttcaacttac taccaactct ctttcctcca aagtttgtat ttactctccc ctcctaactt
      481 actaaaaatt ggaaaatcat ttgtcagtga aaagagaagc agtcatatga gaaactggct
      541 gggagctcag cctcattgct aagcaaatct ttgcaaattc tttttgtcat atctagcagg
      601 gcattttgat ctgtggacaa tactgcccat catgagtagg tccagaattg atcatctcat
      661 ataccaagcc acaagatttt ggctcaaaat gacatcccaa ctttgtacag ggaaatctgt
      721 aaatatactg tgttggtctg caccaagtct tctgagttaa gattttgttt ggactagctc
      781 tgagaattct tggcacagta cttatggatt caggaggtaa gagagtgtta atcccagctt
      841 cccaatttgc taatgatctg agactttttt tttggcaaat ctcatgggag aaatatgaga
      901 ggtgagaaaa atctggataa gcacagatat taaacaacaa aattagaaat gtatggaaat
      961 tttcattgat gcagagacag tgtgatgcat ctggatctga ttgtattgag gctgtggttc
     1021 aatcaggtga ttggattagg ggttcaggcc ttgttcaaaa gtgattactc aatattctga
     1081 tgaacgtgaa gaaaaaaaac tggatttcta tagtagttaa aggtaacaga atatgtaaag
     1141 atagcatgag ctatcatgta ctagtttcct ttatgttgct gtgataaaac actttgacca
     1201 ataccaactg agggtaggaa agggtttatc tagtttatac ttctagataa cagttcatca
     1261 tggagtgcag tcaggacagg aactcaaggt aggaacctgg aggcaggact catagaggga
     1321 caatgcttgt cacaggctta tgcttagctt gctttctcat acaatacagg accaactgtc
     1381 ttgaaatggt actatcaaca gtggtctgga ccctcttatg tcaataagaa taatcaagat
     1441 tgttctccac agacacgtcc acgaggcaat ttgatctaga caacttcttt tttgttttta
     1501 tttatttata tttatttggt tttattaatt tactttatat cctgactata gttcctggcc
     1561 ttccagttcc ccctcccccc attcactcct cctccattta tcttcagaaa atatgtatct
     1621 accacttatg aagttgtagt aagactttgc acatcctctc ttattgaggc caagacaaga
     1681 caggcagtag gagaaaaggg tcccaaaggc aggtgacaga atcagagata tctctaggca
     1741 actttttaat tgaggtcata tccctgtagg ttgtgtcaag tagacaaggt taacatggtg
     1801 acatgatatg gtgtttgggt aatactgtgt gccacagtag ttaaagttat gaagagcaga
     1861 aagtgtgaca gaatagaaag gtaacattag taagagggga aacatacagt tattacatga
     1921 tcaagtacca aggtataaac aaaaccagaa cagcacagac actggagcat cacatattgg
     1981 ggcaagatag gcagacggta accacgtttc tctggtttgg aagcctattg caattcctgt
     2041 ttctggattc ctatgatcat tctcaactat attaagccac ataagattct ccaatgaaca
     2101 aactacttct ctatttgaag agttaaatga acttccatct ttgtcttgta tctgagaatg
     2161 tcatttttac ttctttttga ggaattccca atttggactc ttagaaccgg gatgg
//
