LOCUS       NM_001163575            3307 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus poly (ADP-ribose) polymerase family, member 10
            (Parp10), transcript variant 1, mRNA.
ACCESSION   NM_001163575 XM_001476518 XM_001476537 XM_001477922 XM_001477932
VERSION     NM_001163575.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3307)
  AUTHORS   Gao,X.Q., Zhang,Y.H., Liu,F., Ponnusamy,M., Zhao,X.M., Zhou,L.Y.,
            Zhai,M., Liu,C.Y., Li,X.M., Wang,M., Shan,C., Shan,P.P., Wang,Y.,
            Dong,Y.H., Qian,L.L., Yu,T., Ju,J., Wang,T., Wang,K., Chen,X.Z.,
            Wang,Y.H., Zhang,J., Li,P.F. and Wang,K.
  TITLE     The piRNA CHAPIR regulates cardiac hypertrophy by controlling
            METTL3-dependent N6-methyladenosine methylation of Parp10 mRNA
  JOURNAL   Nat Cell Biol 22 (11), 1319-1331 (2020)
   PUBMED   33020597
  REMARK    GeneRIF: The piRNA CHAPIR regulates cardiac hypertrophy by
            controlling METTL3-dependent N(6)-methyladenosine methylation of
            Parp10 mRNA.
REFERENCE   2  (bases 1 to 3307)
  AUTHORS   Butepage,M., Krieg,S., Eckei,L., Li,J., Rossetti,G., Verheugd,P.
            and Luscher,B.
  TITLE     Assessment of Intracellular Auto-Modification Levels of ARTD10
            Using Mono-ADP-Ribose-Specific Macrodomains 2 and 3 of Murine Artd8
  JOURNAL   Methods Mol Biol 1813, 41-63 (2018)
   PUBMED   30097860
  REMARK    GeneRIF: murine Artd8 macrodomain constructs can serve as a tool to
            evaluate intracellular ARTD10 auto-modification levels using the
            described methods, while the human ARTD8 macrodomains are less
            suited because of ADPr-independent binding to ARTD10. Protocols for
            co-immunoprecipitation and co-localization experiments are
            described in detail.
REFERENCE   3  (bases 1 to 3307)
  AUTHORS   Mihailovska,E., Raith,M., Valencia,R.G., Fischer,I., Al
            Banchaabouchi,M., Herbst,R. and Wiche,G.
  TITLE     Neuromuscular synapse integrity requires linkage of acetylcholine
            receptors to postsynaptic intermediate filament networks via
            rapsyn-plectin 1f complexes
  JOURNAL   Mol Biol Cell 25 (25), 4130-4149 (2014)
   PUBMED   25318670
REFERENCE   4  (bases 1 to 3307)
  AUTHORS   Fuchs,P., Zorer,M., Reipert,S., Rezniczek,G.A., Propst,F.,
            Walko,G., Fischer,I., Bauer,J., Leschnik,M.W., Luscher,B.,
            Thalhammer,J.G., Lassmann,H. and Wiche,G.
  TITLE     Targeted inactivation of a developmentally regulated neural plectin
            isoform (plectin 1c) in mice leads to reduced motor nerve
            conduction velocity
  JOURNAL   J Biol Chem 284 (39), 26502-26509 (2009)
   PUBMED   19625254
REFERENCE   5  (bases 1 to 3307)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY742887.1, AK046755.1 and BP768925.1.
            
            On or before Jul 25, 2009 this sequence version replaced
            XM_001476518.1, XM_001476537.1, XM_001477922.1, XM_001477932.1.
            
            Transcript Variant: This variant (1) represents the predominant
            transcript. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK146336.1, BC024074.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-595               BY742887.1         2-596
            596-3283            AK046755.1         681-3368
            3284-3307           BP768925.1         28-51               c
FEATURES             Location/Qualifiers
     source          1..3307
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 35.57 cM"
     gene            1..3307
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /note="poly (ADP-ribose) polymerase family, member 10"
                     /db_xref="GeneID:671535"
                     /db_xref="MGI:MGI:3712326"
     exon            1..94
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            95..273
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..2984
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /EC_number="2.4.2.30"
                     /note="poly [ADP-ribose] polymerase 10;
                     ADP-ribosyltransferase diphtheria toxin-like 10"
                     /codon_start=1
                     /product="protein mono-ADP-ribosyltransferase PARP10"
                     /protein_id="NP_001157047.1"
                     /db_xref="CCDS:CCDS49650.1"
                     /db_xref="GeneID:671535"
                     /db_xref="MGI:MGI:3712326"
                     /translation="MAEVEAGAALELRGLPPEIPDELITLYFENHRRSGGGLLLSWQR
                     LGCGGVLIFQDPADAKRVLAQAEHRLHGVRLSLRPAPPRAPERVLLQHLPPGTSPLSL
                     EQHVQALLGAAGHPVQTCHALASPRQDCALVQLSTPLSEAEVSALAEQARNLPLNGAT
                     VSLAWVPQTRAVRVVDSASPVDLLLLELYLENERRSGGGPLEGLRSLPGQLGTVISFQ
                     QWQVAERVLKQKHWLQGIELSLVPHYDVLEPEALAEGVSGRDHSATQESGVIGHAPTG
                     TGGLAGALTMAVGSGEAPQQLGTLLRAGPVGAPGQALPVDSGSIRIQGSMGSTSPVDP
                     VESSTELPEQVGPMASDSVGVQEQEGLGEVATGQEGLMGLVGTAMESVETGLESPGYG
                     EMQKQEGLVEMVMSVEPGAVRYLQLYYEDLLASLEDVALFPLEGTDVTGFRLCGARAP
                     CQAAQELLQSLLGSISCHTLNMKHPGSARFLLGVEGQHLLHRLEAQFQCVFGTEHLAS
                     ATLDIDPERTDPTEALQVLHGHITGIDQESLRLEDVRELLATLESPHGGEDRVPLEME
                     KEKPGGPGETVVEQQEEIPTLEAEEEPVALSTGARGQLEEEATLQLAIHRSLESQSQV
                     ADQQEANALRRAMALSLLEAEEALDEDTGGEAQLVVHTSFEQDVDELNQALSNALEAH
                     LREETVSLQGRMLPPELGARLERCHDVSATLRGDRVVLRGFGVQPARAARHLAALLVD
                     PWDQNLTFPLEASKPNLSEQGLKEPLGRLEALEENSQEFQDVVRAFYSTLDAVHGRIR
                     IVRVERVSHPLLQQQYQLHRERLMQSCQQRPVEQVLYHGTSESAVLDICAHGFNRSFC
                     GRNGTLYGQGVYFAKRASLSVLDRYSPPNAEGYKAVFVAQVLTGDYGQGSRGLKAPPL
                     RVSGQVLRYDSAVDCLQQPRIFVIFHDTQALPTHLITCKNILPGTP"
     exon            274..528
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            529..765
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            766..1430
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1652
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1653..1725
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..2370
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2371..2504
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2505..2679
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2680..3291
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3263..3268
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /note="hexamer: AATAAA"
     polyA_site      3284
                     /gene="Parp10"
                     /gene_synonym="ARTD10; PARP-10"
                     /note="major polyA site"
ORIGIN      
        1 agtttcactt ttgttttcct accttaggcc ttctgcctgg gaaggacagc aggcataact
       61 gactggcctg agacactggc ctgagacagc aggggactct gatggcagag gtggaggcag
      121 gggcagcctt ggagctccgg ggactgcccc cagaaatacc agatgagctc attactctgt
      181 actttgaaaa ccaccgtcgc tcgggtggag gacttctatt gagctggcag agacttggct
      241 gtgggggtgt cctcatcttt caagatcctg cagatgcaaa gagggtctta gcccaggcag
      301 agcaccgact acatggtgtc cgactgagcc tgaggccagc cccaccgcgt gccccagaac
      361 gtgtgcttct ccaacacctg ccacctggca cttcacctct gagtctggag caacatgttc
      421 aggccttgct gggtgctgca ggacaccccg tgcagacttg ccatgccctg gccagtcctc
      481 ggcaggactg tgccctggtc cagttatcca cgcccctttc tgaggcagag gtcagtgccc
      541 tggcagaaca ggcccggaat ctgcccctga atggagccac tgtgtccttg gcctgggtgc
      601 cccagacccg agcagtacgt gtggtggaca gtgcttctcc tgtggacctg ttattgttgg
      661 agctctacct ggaaaatgag cgtcgcagtg gtggcggacc cctggagggt ctgcgcagcc
      721 tgcctgggca gctaggcact gttatttcct ttcagcaatg gcaggtggct gaacgggtgc
      781 tgaagcagaa acactggcta cagggcattg agttgagcct tgtccctcac tatgatgtct
      841 tagagccaga agcgctcgct gagggcgtca gtggcaggga ccattcagct actcaagaat
      901 ctggagtcat tggtcatgcg cctacaggaa ctggaggact ggccggggct ctgaccatgg
      961 ctgtgggctc tggggaggca ccacaacaat taggaaccct tctaagggca ggtcctgtag
     1021 gagctccagg acaagccctg ccagttgact cgggatcaat taggatccag gggagtatgg
     1081 ggtctacaag cccagtcgat ccagtagaga gctctacaga gctcccagag caagtaggac
     1141 ccatggcctc agactcagtg ggtgttcagg agcaggaggg cctgggggaa gttgccacag
     1201 ggcaagaggg gctaatgggt ctagtgggga cagccatgga gtctgtagag actgggctgg
     1261 agagccctgg gtatggggag atgcagaagc aagagggcct ggtggaaatg gtgatgtcag
     1321 tggaaccagg agctgtgcgc tacctgcagc tttattatga ggacctcctc gccagcctag
     1381 aagatgttgc ccttttccca cttgaaggaa cggatgtgac tggctttcgg ctgtgtggag
     1441 ccagggcccc ctgccaggca gcccaagagt tgcttcagag tctgctgggc agcattagct
     1501 gtcacacgct gaacatgaag cacccgggca gtgccaggtt cctgctgggt gtggaggggc
     1561 agcaccttct tcacagactg gaggctcagt tccagtgtgt cttcgggaca gaacatctgg
     1621 ccagcgccac cctggacata gaccctgaaa ggacagatcc cactgaggcc ctccaagtcc
     1681 tccatggcca cattacaggc atcgatcagg agagcttgag actggaggac gtccgagagc
     1741 tactggctac cctggagagc ccacatggag gggaggacag ggtgcctctg gagatggaga
     1801 aggagaaacc tggaggacca ggagagactg ttgtagagca gcaggaggaa atccccacac
     1861 ttgaggctga ggaggagcct gtggccctta gcaccggggc acgtgggcag ttagaagaag
     1921 aagccacact tcaactggct atccaccggt ccttggagtc tcaaagccag gtggcagatc
     1981 agcaggaggc taatgcacta aggcgagcca tggccctttc cctgttagaa gcagaagagg
     2041 ccctggatga ggacactggg ggcgaggccc agctggtggt gcacacatcc tttgagcagg
     2101 atgtggatga attgaaccag gccttatcca atgccttgga ggcacacctt cgggaggaga
     2161 cagtgagtct ccaagggcgc atgctacccc cggagctggg ggctcgtctg gaaaggtgtc
     2221 atgatgtgag tgctaccctc cgtggcgacc gagttgtcct ccgtggcttt ggggtccagc
     2281 ctgcccgcgc ggctcgccac ttagctgctc tgcttgttga cccctgggac cagaatttga
     2341 cctttccttt ggaggcttca aaacccaact tgtctgagca ggggctgaag gaacccttgg
     2401 gcagactgga ggccctggaa gagaattccc aggagttcca agatgtggtg cgggcctttt
     2461 atagcaccct ggatgctgtc cacggcagga tccgcattgt tcgagtagaa cgcgtgtcac
     2521 acccattgct gcagcaacag taccagctgc accgggagcg tttaatgcag agctgccagc
     2581 aacgcccagt ggagcaggtc ctctaccatg gcacttcaga gtctgcagtg ctcgacatct
     2641 gtgcgcacgg cttcaatcgc agtttctgtg gccgaaacgg cacactctac ggacagggcg
     2701 tgtacttcgc caagcgtgcc tctctgtcgg tactggatcg ctactcgcct cccaacgcag
     2761 aaggctacaa ggcagtgttt gtggcacagg tgctgacggg tgactatgga cagggttccc
     2821 gcggtctgaa ggcacctcct ttgagggtct ccggtcaggt gcttcgctac gacagcgctg
     2881 tggactgcct tcagcagccc agaatctttg tcatctttca cgatacccaa gctttaccga
     2941 ctcatctaat cacctgcaag aacatactcc cgggtacccc ctgataactc tcttggtctc
     3001 ttggatctct ttcctggaca tttgacctaa gaggccagct tctggttccc tgctctacaa
     3061 agtccttaag tgtcagagct gcccacggga gcactcctgt ctttggctgg atagacagga
     3121 tgactgtgga ctggggaggg ccagacctaa tggttccttg gcctgctcga ccgccagggg
     3181 tcagcagaac acggcaggag ggagcaccgc cagacacacc cgtcttggtt ggaccgcgcc
     3241 ctagaggggt tctctgtctt tgaataaacc tgtacttgaa accagttaga aaaaaaaaaa
     3301 aaaaaaa
//
